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開結舒經湯(개결서경탕) 투여를 포함한 동결견 환자 한방복합치료 치험례 1례
최기원,이유진,권민진,박한빈,장원석,김호,배인수,윤준흠,Choi, Ki-won,Lee, Yu-jin,Kwon, Min-jin,Park, Han-bin,Jang, Won-suk,Kim, Ho,Bae, In-su,Youn, Jun-heum 대한한방내과학회 2021 大韓韓方內科學會誌 Vol.42 No.5
Background: This case study suggests the potential usefulness of Korean medicine treatment with herbal medicines for shoulder pain and improving the quality of life of patients with frozen shoulder. Case Summary: A patient had shoulder pain and decreased daily living function due to frozen shoulder. Korean medicine treatments, including herbal medicine; acupuncture at points TE14, HT1, BL11, SI10, and LI15; and pharma-acupuncture containing Sinbaro, were applied for 31 days. The Numeric Rating Scale scores for shoulder pain decreased from 7 to 4, and the Shoulder Pain and Disability Index scores decreased from 71.54 to 66.15, with an increase in range of motion from 30° flexion, 60° abduction, and 10° external rotation to around the normal range of motion. Conclusion: Korean medicine treatment can be considered an effective conservative management option for pain and decreased daily living function in patients with frozen shoulder.
최기원(Ki Won Choi),황우진(Woo Jin Hwang),원종서(Jong-Seo Won) 대한설비공학회 2017 대한설비공학회 학술발표대회논문집 Vol.2017 No.6
본 연구는 개정된 건축물의 에너지절약 설계기준을 만족하기 위한 AL커튼월에 대해 연구하였다. 고사양 유리와 단열 강화 프레임을 사용하여 AL커튼월의 열성능을 향상하였다. 프레임 열관류율 3.0 W/㎡・K 이하를 만족하는 디테일을 구현하기 위해서 크게 두 가지 요소 기술이 적용이 되었다. 열교차단재인 Polyamide를 적용하여 공간에서의 열전달을 차단하는 기술과 Vent창 유리 하부에 유리를 지지하는 부위를 기존 알루미늄 프로파일의 단일재료 구조에서 Polyamide와 결합하여 구성함으로써 외기에 직접 면하는 부위에서의 열전달을 최소화하였다. 이를 통해 Fix기준으로 프레임 열관류율이 약 13%의 성능이 향상되었고, Vent기준으로는 약 24%의 성능이 향상되었다. 커튼월 시스템의 시뮬레이션 결과를 보면, Fix 타입은 커튼월 시스템 열관류율 1.410~1.472 W/㎡・K로 분석되었고, Fix+Vent 타입은 커튼월 시스템 열관류율 1.438~1.482 W/㎡・K로 분석되어 상향된 법규 기준 1.5 W/㎡・K 이하를 충족하는 것으로 나타났다.
최기원 ( Ki Won Choi ),윤세진 ( Sei Jin Youn ),한정호 ( Joung Ho Han ),전원중 ( Won Joong Jeon ),채희복 ( Hee Bok Chae ),박선미 ( Seon Mee Park ) 대한소화기기능성질환·운동학회 2005 Journal of Neurogastroenterology and Motility (JNM Vol.11 No.2
목적: Peptide YY (PYY)는 장관에서 작용이 다양하며 운동에 미치는 기전은 명확하지 않다. 관류가 유지되고 혈관 및 신경이 보존된 상태의 흰쥐 결장을 이용하여, PYY가 결장운동에 미치는 영향을 관찰하여 위치에 따른 차이 및 그 작용기전을 알아보고자 하였다. 대상 및 방법: 상장간막동맥을 포함하여 분리한 흰쥐 결장에서 PYY를 12 pM, 60 pM, 240pM을 단계적으로 동맥을 통해 투여하여 근위부와 원위부 결장 내압을 측정하였다. 운동성은 각 농도별 약물투여 시 운동지수를 계산하여 백분율 변화로 표시하였다. 억제 실험은 근위부는 240 pM의 PYY 투여 때와 비교하였고, 먼저 phentolamine, propranolol, hexamethonium, atropine, tetrodotoxin 각각을 관류시킨 후 PYY를 같이 투여하면서 운동성 변화를 측정하였다. 결과: PYY를 12, 60, 240 pM 농도로 순서대로 투여할 때 근위부 결장에서 수축지수는 각각 22.53±6.12, 27.31±6.07, 33.93±8.55%이었고, 원위부 결장에서 수축지수는 각각 6.74±4.45, 37.79±11.53, 52.77±11.36%로 기저치에 비해 근위부와 원위부 결장에서 모두 수축지수가 유의하게 증가하였다(p<0.05). 결장 수축지수의 증가 정도는 근위부와 원위부 결장 사이에 유의한 차이가 없었으나 원위부에서는 주입된 PYY의 용량이 증가함에 따라 수축지수가 용량 의존적으로 증가하였다(p<0.05). PYY (240 pM)에 의해 증가되는 결장운동은 atropine, propranolol, tetrodotoxin 전처치에 의해 통계적으로 유의하게 억제되었지만(p<0.05), phentolamine과 hexamethonium 전처치에는 억제되지 않았다. 결론: PYY는 흰쥐 결장운동을 촉진시키는 작용이 있으며, 이러한 결장 평활근 수축 촉진 작용은 무스카린수용체를 통한 콜린성 신경 또는 베타 아드레날린성 신경의 국지적인 영향 하에 있음을 확인하였다. Background/Aims: The mechanism by which peptide YY (PYY) stimulates colonic motility has not yet been fully elucidated. The aim of this study was to investigate PYY`s mechanism of action on isolated rat colon. Methods: An isolated rat colon was perfused with Krebs solution via the superior mesenteric artery. After a basal period, PYY was administered at concentrations of 12, 60 and 240 pM, respectively, and the intraluminal pressures were then monitored. After a pre-infusion of phentolamine, propranolol, hexamethonium, atropine, and tetrodotoxin, PYY was infused at a concentration of 240 pM and the pressures were then monitored. The contractile response was expressed as the % changes of the motility indices over the basal rates. Results: The colonic motility increased significantly at the concentration of PYY of 12, 60 and 240 pM at the proximal colon (22.53±6.12%, 27.31±6.07%, and 33.93±8.55%, respectively) and the distal colon (6.74±4.45%, 37.79±11.53%, and 52.77±11.36%, respectively). PYY displayed a dose-dependent increment on distal colonic motility. The stimulatory effect of PYY was almost completely abolished by a pre-treatment with atropine, propranolol, and tetrodotoxin; However, the effect of PYY was not inhibited by hexamethonium and phentolamine. Conclusions: PYY increased the colonic motility, and the stimulatory action of PYY requires local cholinergic input via the muscarinic receptors or adrenergic input via the beta-receptors. (Kor J Neurogastroenterol Motil 2005;11:142-151)
만성 폐쇄성 폐질환 환자에서 수면중 저산소혈증의 예측지표
최기원(Ki Won Choi),김혜영(Hye Young Kim),박남규(Nam Gyu Park),곽남주(Nam Ju Kwak),오태근(Tae Geun Oh),김동운(Dong Woon Kim),김승택(Seung Taik Kim),이상도(Sang Do Lee) 대한내과학회 1996 대한내과학회지 Vol.51 No.4
N/A Objectives: In chronic obstructive pulmonary disease, nocturnal hypoxemia is associated with pulmonary hypertension, arrhythmia and increased mortality during sleep. So a noninvasive, inexpensive method of predicting significant sleep-associated nocturnal hypoxemia would be desirable for patients being investigated and treated for chronic obstructive pulmonary disease. This study was performed to identify the incidence and accurate predictive indicators for nocturnal hypoxemia in these patients. Methods: We measured nocturnal SaO2 during sleep and overnight change of urinary uric acid/creatinine ratio and performed daytime arterial blood gas analysis and pulmonary function test in twenty-eight patients with chronic obstructive pulmonary disease. Results: 1) Nocturnal hypoxemia occurred in 12 of 28 COPD patients (43%), 9 of 13 blue-bloaters (70%) and 3 of 15 pink-puffers (20%). The incidence of nocturnal hypoxemia was higher in blue-bloaters than pink-puffers (p<0.05). 2) Daytime PaO2 was lower and PaCO2 was higher in hypoxemia group than those of normoxemia group (p<0.05). 3) There was significant correlation between daytime PaO2 and nocturnal lowest SaO2 in hypoxemia group (r=0.72, p<0.05). 4) There were no correlations between daytime PaO2 and nocturnal mean SaO2 and between daytime PaCO2 and lowest or mean nocturnal SaO2 in hypoxemia group. 5) Overnight change of urinary uric acid/creatinine ratio was not significantly different between hypoxemic and normoxemic group. 6) There was no significant difference in pulmonary function test values between hypoxemic and normoxemic group. Conclusion: These data indicate that daytime PaO2 is an useful indicator to predict nocturnal hypoxemia in chronic obstructive pulmonary disease but overnight change of urinary uric acid excretion is not.
만성 족관절 불안정증에서 건이식을 이용한 외측 인대 재건술의 적응증
박재용,최기원,조재호,강찬,최경진,정진화,김학준,배서영,차승도,김기천,한승환,2015 대한족부족관절학회 보험장애판정위원회,Park, Jae Yong,Choi, Gi-Won,Cho, Jae-ho,Kang, Chan,Choi, Kyungjin,Chung, Jin-Wha,Kim, Hak Jun,Bae, Su-Young,Cha, Seung-Do,Kim, Ki Ch 대한족부족관절학회 2016 대한족부족관절학회지 Vol.20 No.1
Purpose: The purpose of this study is to review the indications of ankle lateral complex reconstruction using tendon graft. Materials and Methods: We searched PubMed using the index, "ankle, instability, lateral ligament, reconstruction" from 1990 to present (September 30, 2015). We excluded 1) modified Brőstrom operation (MBO), 2) conventional tenodesis surgery, 3) review article, 4) technical note, and 5) articles written in another foreign language. We reviewed 24 papers through the publication events, operational method, the indications of surgery, and the specific features of the patient group. Results: There were the indications of 1) previous ligament surgery failure, 2) situation when ligament repair is impossible due to the ligament defect, 3) severe instability (preoperative talar tilt >$15^{\circ}$, anterior draw >10 mm or the difference of contralateral side talar tilt >$5^{\circ}$, anterior draw >3 mm), and 4) overweight (body mass index >$30kg/m^2$). Other considerations included 1) generalized joint laxity and 2) workers, highly-demanded or athlete highly-affected by instability. Conclusion: The ankle lateral complex reconstruction using tendon graft could be indicated in patients with the possibility of MBO failure with several considerations.