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리파오돌 화학색전이 정상 간에 미치는 영향에 관한 실험적 연구
주인욱 대한영상의학회 1991 대한영상의학회지 Vol.27 No.1
The hepatic artery chemoembolization with Lipiodol, doxorubicin, Gelfoam was performed in 14 mongrel dogs to evaluate embolic effect of these materials to normal liver parenchyma. Fourteen dogs were divided into four experimental groups according to the kinds of embolic materials, 3 dogs with 0.1ml/kg of Lipiodol(Group 1), 4 dogs with 0.1ml/kg of Lipiodol and 0.5mg/kg of doxorubicin(Gruop 2), 4 dogs with Lipidol, doxorubicin and 150-300 pieces of 0.5x0.5cm sized Gelfoam(Group 3), 3 days, 1 week, 2 weeks and 3 weeks after embolization. Pathologic examination was performed 3 weeks after embolization. Lipiodol densities in group 1 were cleared 2 weeks after embolization, and in group 2, patch and nodular Lipiodol densities were changed to mottled and streaky densities 3 weeks after chemoembolization. In group 3, patch and nodular Lipiodol densities were still remained 3 weeks after chemoembolization. Histopathologic examination showed nonspecific pathologic changes such as fatty change of hepatocyte or intravascular congestion in group 1 and 2. However, in group 3 and 4, there were significant pathologic damages of the liver such as hepatocellular necrosis and interstitial hemorrhage. In conclusion, Lipiodol-CT for the diagnosis of hepatic tumors is recommended to be performed 2 weeks after Lipiodol infusion, and in case of chemoembolization with Lipiodol and Gelfoam, superselection of supplying vessels of tumors is necessary to avoid the possible parenchymal damage of the normal liver.
경피경간담배액술 후 혈중 빌리루빈치 상승예에 관한 분석
주인욱 대한영상의학회 1986 대한영상의학회지 Vol.22 No.6
The aim of percutaneous transhepatic biliary drainage IPTBD) is to decrease serum bilirubgin level and promote liver function in patient with biliary tract disease, especially obstruction by malignant disease. But some patients showed persistient high serum bilirubin level or higher than pre-PTBD level. Percutaneous transhepatic biliary drainage was performed in 341 patients of obstructive jaundice for 5 years from July, 1981 to July , 1986 at department of radiology, Seoul National University Hospital. Follow up check the serum bilibrubin level was possible in 188 patients. Among them the authors analysed 32 patients who showed persistent high serum bilirubin level after PTBD. The results were as follows : 1. The male to female ratio was 3.4 : 1 and the age ranged from 33 to 75. 2. The causes of obstructive jaundice included 30 malignant diseases and 2 benign diseases. Malignant disease were 16 cases of bile duct cardinoma, 7 cases of pancreatic cancer and 7 cases of matasta is from stomach, colon and uterine cervix. Benign diseases were 1 cases of common hepatic duct stone and 1 case of intrahepatic duct stones. 3. The most common level of obstruction was trifurcation in 17 cases. 4. The most common indication of PTBD was palliative drainage of obstruction secondary to malighant tumor in 28 cases. 5. Change of serum bilirubin level ratio (post-PTBD level/pre-PTBD level) was 1.28, 1.22, 1.38, 1.51 in serial period of 1-3 days, 4-6 cays, 1-2 week 2-3 week after PTBD. 6. Causes of persistent high serum bilirubin level after PTBD were 12 cases of partial drainage of intrahepatic bile, 13 cases of hepatic dysfunction including 9 cases of metastatic nodule, 2 cases of biliary cirrhosis, 2 cases of multiple liver abscess, and 7 cases of poor function of catheter including 4 cases of hemolibilia, 1 cases of multiple intrahepatic stones, pyobilia and intrahepatic Clonorchis sinensis.
재래식 혈관조영 카테타를 사용한 뇌 동정맥기형의 경피적 동맥색전술
주인욱 대한영상의학회 1988 대한영상의학회지 Vol.24 No.6
Non-surgical transfermoral embolization of centrally located huge intracerebral arteriovenous malformation (AVM) was successfully performed by using conventional 6.5F DAVIS II Catheter in the department of Radiology Kangdong Sacred Heart Hospital May 17 1988. The large A.V.M. was located in left basal ganglia and thalamus on brain C. T. and was supplied by multiple dilated lateral lenticulostriate arteries from left middle cerebral artery and posterior thalamoperforating artery posterior choroidal artery from left posterior cerebral artery angiographically. The AVM (Palyvinyl Alcohol ivalon)using conventional 6.5F DAVIS II angiographic catheter. There was no complication which was related to those embolization procedures except transient drowsy consciousness after embolization but it is completely recovered to the level of preembolization state after 10 hours.
서승근,어환,주인욱,송준호,박세혁,정봉섭,권병덕,이규호 대한신경외과학회 1988 Journal of Korean neurosurgical society Vol.17 No.5
Selective arterial embolization can reduce the size and pressure within the nidus of the arteriovenous malformations (AVMS) and diminish the number of feeding pedicles, making subsequent surgical excision technically easier and safer, especially in those AVM patients whose lesions are judged to be inoperable or resectable with major risk. Authors have successfully and repeatedly performed selective arterial embolizations with polyvinly alcoholfoam(PVA foam) and isobuty1-2-cyanoacrylate (IBCA) to a large AVM at the left basal ganglia, thalamus and lateral ventricles, and a large cortical AVM near right motor strip.