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후두 및 기관협착증의 유발 인자로서의 위산 및 펩신의 역할에 관한 실험적 연구
조재식,유영채,김승현,이종원 대한기관식도과학회 1995 大韓氣管食道科學會誌 Vol.1 No.1
Gastroesophageal reflux is thought to be an important etiology of the various upper aerodigestive tract disease. To investigate the role of gastric acid and pepsin as an etiologic factor of laryngotracheal stenosis, and the difference of injury by synthetic gastric juice between in ciliated respiratory epithelium and in squamous epithelium, experimental study was carried out using rabbits. Mucociliary transport affected by synthetic gastric juice was also studied in dogs. Synthetic gastric juice of low pH caused serious damage and Impairment of mucociliary transport in the epithelium of the larynx and trachea. Gastric acid played major role in the mucosal damage. Squamous epithelium of vocal folds and pharynx was more resistant to synthetic gastric juice than respiratory epitheium. In conclusion, gastroesophageal reflux may be an etiologic factor in the developement of laryngotracheal stenosis, so the adequate management is necessory In patients of laryngotracheal stenosis.
비강 및 부비동의 반전성 유두종에서 인형유두종 및 Ebstein-Barr 바이러스의 검출
조재식,임상철,백준,정형수,신명석,Cho, Jae-Shik,Lim, Sang-Chul,Baik, Jun,Jeong, Hyoung-Soo,Shin, Myoung-Seok 대한기관식도과학회 1999 大韓氣管食道科學會誌 Vol.5 No.1
The etiology of inverted papilloma(IP) remains unknown, but several studies have reported that Human Papillomavirus(HPV) may play a role in the pathogensis of sinonasal inverted papilloma(IP). And recent reports demonstrate the possible etiologic role of Epstein-Barr virus (EBV) in sinonasal IP. The aim of this study is to detect HPV and EBV in sinonasal IP, to examine the relationship between HPV subtype and sinonasal IP, to investigate the relation between HPV and EBV. We reviewed 30 cases of sinonasal IP(simple IP 19 cases, IP with dysplasia 8 cases, IP with squamous cell carcinoma 3 cases). Paraffin embedded archival tissue was used in this study. Detection of HPV, EBV were examined by in situ hybridization(ISH) using HPV type 6/11, 16/18, 31/33/35 DNA probe and EBER probe. The HPV was detected in 6(20%) out of 30 cases. The HPV 6/11 was dectected in 4 out of 19 cases of simple IP, HPV 16/18 in 1, HPV 31/33/35 in 1 out of 8 cases of IP with dysplasia respectively. The EBV was not detected in 30 cases. HPV may play a role in the pathogensis of sinonasal inverted papilloma. But EBV is not a etiopathologic factor to be considered in the development of sinonasal IP.
조재식,이상철,임상철,김종식,박종부,심우진 대한기관식도과학회 1997 大韓氣管食道科學會誌 Vol.3 No.1
최근 5년간 전남대학교 병원에서 두경부암으로 치료받은 52명의 환자를 대상으로 시행한 갑상선기능 검사를 분석하여 다음과 같은 결과를 얻었다. 1. 두경부암 환자에서 방사선 치료와 수술을 병행하여 치료한 경우에서 갑상선기능저하증 발생빈도가 높았고, 특히 후두적출술을 시행한 경우는 위험성이 증가되었다. 2. 종양의 임상병기가 높을수록, 원발병소가 설골 하부인 경우에서 병합요법을 시행할수록 갑상선기능저하증 발생빈도가 높았다. 3. 연령, 성, 방사선 조사량, 치료후 갑상선 검사까지의 기간 사이에는 갑상선기능저하증 발생에 통계학적으로 의의 있는 인자는 없었다. 따라서, 위험군에서는 추적관찰 도중 갑상선기능 저하증의 임상적 증후를 주의 깊게 관찰하고, 정기적인 갑상선 기능 검사를 통해 조기 발견해서 levothyroxine 보충치료로 임상적 갑상선기능저하증으로의 진행을 예방하여야 한다. Hypothyroidism is not uncommon complication of therapy for head and neck cancer. A series of 52 patients treated with either radiotherapy alone or combined with surgery was retrospectively studied. Diagnostic procedure included total T3, T4 and TSH measured by radioimmunoassay. The rate of hypothyroidism was 25% (subclinical 15.4%, clinical 9.6%). The incidence of hypothyroidism increased to 40% when radiotherapy was combined with surgery. Risk factors influenced a high incidence of hypothyroidism were : tumor stage, primary tumor site, combination of radiotherapy and surgery (especially combined with laryngectomy). We advocate routine monitoring of head md neck cancer patients for hypothyroidism after treatment and recommend levothyroxine replacement therapy for subclinical hypothyroidism.
조재식,김정현,윤제환,문석진 대한이비인후과학회 2002 대한이비인후과학회지 두경부외과학 Vol.45 No.7
Thornwaldts cyst is a rare benign developmental lesion induced by persistent notocord remnants within the midline nasop-harynx. Although most patients with the cyst are symptom-free, inflamation or an absces can develop. Treatment involves rette, scissors, and so on. But recently by introduction of nasal endoscopy and its extended application, transnasal approach using nasal endoscopy becomes useful surgical approach to nasopharynx. We report a case of Thornwaldts cyst which was successfuly removed with nasal endoscopy in a 30-year-old man. (Korean J Otolaryngol 2002;45:722-4)
LoRa Netwrok 환경에서 Assisted GPS를 활용한 위치측위 성능 개선 방안
조재식,황동엽,김기형 한국정보통신설비학회 2018 한국정보통신설비학회 학술대회 Vol.2018 No.08
LoRa, one of the low power wide area (LPWA) communications technologies, enables low cost chip module design and cost savings due to low power, high receiver sensitivity and license-exempt bandwidth. In particular, smart metering and GPS tracking are attempting to construct a network using LoRa technology because the amount of transmission is relatively smaller than the frequency of data transmission. Especially in the field of GPS tracking, location positioning may fail or slow down because of various environmental variables. In this paper, we propose to construct an Assisted GPS system when constructing GPS tracking environment using LoRa to increase the range and speed of positioning in harsh environment.