유리피판 시대의 두경부 재건수술에 사용한 광배근유경피판 6예

정현정,최익준,김광현,하정훈 대한이비인후과학회 2011 대한이비인후과학회지 두경부외과학 Vol.54 No.2

Reconstruction with free flaps has become the choice of reconstruction for most patients with head and neck defects. However, pedicled flaps, such as pectoralis major pedicled flap and latissimus dorsi pedicled flap (LDPF), can also be used instead in selected patients. We performed LDPFs in 6 patients from November 2007 to September 2009. Five of the patients were females with either vascular diseases or large skin defects, or they were highrisk old patients. One male patient received LDPF as a salvage after tongue reconstruction with a free flap failed. Various types of head and neck defects were effectively managed with LDPF without complications. LDPF can be one option for head and neck reconstruction especially in patients who may hve high risk in undergoing free flap reconstruction.

새터민 아동의 문화적응 스트레스 감소를 위한 음악심리치료 적용 연구

정현정,Chung, Hyun Chung 한국음악치료교육학회 2009 음악치료교육연구 Vol.6 No.1

본 연구의 목적은 최근 수적인 증가와 더불어 문화적응에 따른 스트레스를 경험하고 있는 새터민 아동들에게 음악심리치료 프로그램을 실시하여 참여자들의 문화적응 스트레스에 어떠한 효과를 미치는지 알아보는 데 있다. 이를 위하여 새터민 아동 4명을 대상으로 하여 약 40분씩 총 14회기에 걸쳐 개인 세션으로 진행하였다. 본 연구에서는 단일집단 사전사후 검사 설계에 기초하여 14회 활동의 사전과 사후에 문화적응 스트레스 검사를 실시하여 점수를 비교분석한 결과 대상자들의 문화적응 스트레스 점수가 사전검사 평균 32.75점에서 사후검사 평균 23점으로 9.75점 감소하였으며, 각 회기별 주제에 대한 대상자들의 언어적 반응을 분석한 결과 언어적 자기표현에 있어서 부정적 사고가 긍정적 자기인식으로 변화하였음을 알 수 있었다. 이러한 결과는 음악심리치료 프로그램이 새터민 아동에게 음악을 통한 일관된 지지감을 제공하며 긍정적 자아 지각을 통해 내적 자원을 강화하도록 하여 문화적응 스트레스의 감소에 효과적인 중재가 될 수 있음을 시사한다. This study aims to conduct a music psychotherapy program on North Korean child defectors, who are experiencing acculturative stress, and to discover the effects of the program on the participants' acculturative stress. This study targeted four North Korean child defectors, who belonged to an H afterschool class in Seoul and performed the program in individual sessions for about 40 minutes per session, totaling 14 sessions. The research results include the following. First, after comparing the results of acculturative stress score that measured before and after the execution of the music psychotherapy program, the mean of the score was significantly decreased from 32.75 to 23 average. Furthermore, as a result of conducting a qualitative analysis of the lingual responses that the participants demonstrated in musical activity, in relation to acculturative stress, the participants were found to experience a positive change. These results imply that the music psychotherapy program offers consistent support through music to North Korean Child Defectors, who are cowering psychologically and experiencing difficulty in adaptation, and reinforces inner resources through their positive self-perception, which indicates that it can be an effective mediation in reducing their acculturative stress.

나노복합체를 함유한 XLPE의 전류밀도에 미치는 온도의 영향

정현정,양이슬,남진호,남기준,김동욱,Jung, Hyun-Jung,Yang, Yi-Seul,Nam, Jin-Ho,Nam, Gi-Joon,Kim, Dong-Wook 한국전기전자재료학회 2019 전기전자재료학회논문지 Vol.32 No.5

In this study, the volume resistivity of XLPE materials with various voltage ratings was discussed. The volume resistivity of the developed XPLE nanocomposite was measured, and the conductivity mechanism of the material was also examined. The ASTM D 257 and IEC 60093 measurement methods were used for these tests. The equipment was designed to measure up to a temperature of $200^{\circ}C$, and the electrode structure was designed to maintain the thickness and temperature uniformity of the sample. The conductivity of the sample decreased with temperature, and the samples reached saturation within 500s, after which the conductivity leveled off. By analyzing the current density and the electric field, we can well explain the electric conductivity behavior of our sample with the Schottky mechanism.

급성췌장염 후 발생한 후복막강 농양 환자에서 십이지장 누공을 통한 내시경배액술

정현정,정석,이돈행,최윤아,김형길,신용운,김영수,박병도 대한소화기내시경학회 2009 Clinical Endoscopy Vol.38 No.2

The incidence of retroperitoneal abscess with fistula formation after acute pancreatitis is rare, but the mortality rate for patients with this condition is very high. The standard treatment for this condition has been surgical removal and drainage. However, recent studies have shown that percutaneous catheter drainage or noninvasive endoscopic abscess drainage with using endoscopic ultrasonography is effective and safe for the treatment of pancreatic and peripancreatic abscess. A retroperitoneal abscess with duodenal fistula that developed after acute pancreas and its endoscopic treatment has never been reported on in Korea. We experienced a 45-year-old man who had been treated for acute pancreatitis at other hospital, and he was then referred to our hospital and diagnosed as having a retroperitoneal abscess with fistula, which communicated with the third portion of duodenum, as assessed by abdominal CT and duodenoscopy. So we treated him with endoscopic double-pigtailed stent insertion through the fistulous tract and we drained the abscess. Endoscopic drainage may be a suitable alternative for the management of the retroperitoneal abscess with fistula that develops after acute pancreatitis. 급성 췌장염 후 후복막강 농양이 발생하고 이 농양이 소화관과 누공을 형성하는 경우는 빈도가 드물지만 신속한 치료가 이루어지지 않을 경우 사망률이 매우 높은 심각한 합병증이다. 급성 췌장염 후 발생한 췌장 또는 췌장주위 농양은 그 동안 수술이 일차적인 치료방법이었으나, 최근 경피도관배액술이나 내시경초음파를 이용한 경벽배액술 등의 비수술적 치료가 좋은 성적을 보이고 있다. 십이지장 누공이 동반된 후복막강 농양에서 내시경치료에 대한 국내 보고는 아직 없다. 저자들은 43세 남자가 음주 후 발생한 급성 췌장염으로 타 병원에서 치료 도중 후복막강 농양이 발생하여 본원으로 전원 된 후 시행한 십이지장경검사에서 후복막강 농양과 십이지장 제3부사이의 누공을 관찰하고, 내시경으로 누공을 통해 이중 돼지꼬리형 플라스틱 스텐트를 유치시켜 치험한 1예를 경험하여 보고한다.

장애인 부모를 가진 비장애 성인자녀의 성숙 변화 과정에 관한 연구 : 원가족 환경 경험을 중심으로

정현정 보건의료산업학회 2012 보건의료산업학회지 Vol.6 No.1

[경상남도주민자치회] “주민자치 제대로 해 보자” 열기 후끈

정현정 한국자치학회 2015 월간 주민자치 Vol.47 No.-

속삭임게임을 활용한 체계적 환자사정 및 보고 교육프로그램의 개발 및 학습자 경험탐색

정현정 한국엔터테인먼트산업학회 2019 한국엔터테인먼트산업학회논문지 Vol.13 No.6

환자의 악화되는 변화를 인지하여 생명을 구하기위해서는 환자사정과 보고가 초석이 되어야 하지만이 업무는 주로 간호학생 혹은 경험이 부족한 간호사에게 위임되고 있다. 그러나 현재 국내의 교육과정에서는 환자사정 및 보고에 대한 체계적 교육이 이루어지고 있지 않다. 속삭임게임은 첫 번째 사람이선택한 단어나 구 혹은 문장을 팀원에게 속삭여 전달한 후 최종적으로 원본 메시지가 전달과정에서 얼마나 많은 변화가 있었는지를 확인하는 게임이다. 본연구에서는 소아전문소생술과정에서 사용하는 DVD 에 포함된 환아의 정보를 전달하는 속삭임게임프로그램을 개발하고 이를 4학년 간호학생 31명을 대상으로 4회 적용 후 성찰일지 내용분석으로 학습자의경험을 탐색하였다. 연구결과 학습동기 유발, 메타인지능력, 상황맥락학습이라는 3개의 주제가 도출되었다. 속삭임게임을 통한 반복 연습은 간호학생들이 상황과 맥락 속에서 환자를 사정하고 정보를 전달하는과정을 메타인지하게 하는 신선하고 흥미로운 학습방법으로 확인되었으므로 널리 활용되기를 기대한다 In order to save lives by recognizing the deteriorating changes of the patients, patient’s assessment and reporting should be foundation, but this task is mainly delegated to nursing students or inexperienced nurses. A whisper game is a game in which the first person whisper selects a word, phrase or sentence and delivers it to the team member and finally confirms how many original message have changed during the transmit process. The purpose of this study was to develop a whisper game program to transmit the information of the children included in the DVD using in the pediatric advanced life support process. After four times of games, the experiences of 31 nursing students in the fourth grade were explored by analyzing the reflective journal. The results of the study showed three themes: learning motivation, metacognitive ability, and situated contextual learning. Repeated practice through a whisper game is expected to be widely used because it has been identified as a fresh and interesting learning method that enables nursing students to metacognize the process of assessing patients and conveying information in the contextual situation.

전대뇌동맥 경색으로 인한 뇌량 분리 증후군 환자의 치험 1례

정현정,황주원,조은영,최동준,한창호,정승현,신길조,이원철,Jung, Hyun-Jung,Hwang, Joo-Won,Jo, Eun-Young,Choi, Dong-Jun,Han, Chang-Ho,Jung, Seung-Hyun,Sin, Gil-Jo,Lee, Won-Chul 대한한방내과학회 2006 大韓韓方內科學會誌 Vol.27 No.3

A callosal disconnection syndrome results in the functional independence of each hemisphere caused by ACA infarction, head injury or callosal operation for epilepsy. Clinical features are characterized by left unilateral tactile anomia, left unilateral agraphia, left unilateral apraxia, difficulty in copying drawings, dyscalculia and alien hand syndrome. Taeumchowe-tang(太陰調胃湯) is used to treat Taeumin(太陰人) Wewansuhanpyohanbyung(胃脘受寒表寒病). A 47 year-old man, following callosal infarction, was detected on MRI with left agraphia, dyscalculia and alien hand syndrome, but no left ideomotor apraxia or left apraxia. He was treated with Taeumchowe-tang. Significant improvement of clinical symptoms was seen, so it is here reported.

The Ketogenic Diet Suppresses the Cathepsin E Expression Induced by Kainic Acid in the Rat Brain

정현정,김호정,김윤경,박상규,강동원,윤도준 연세대학교의과대학 2010 Yonsei medical journal Vol.51 No.5

Purpose: The ketogenic diet has long been used to treat epilepsy, but its mechanism is not yet clearly understood. To explore the potential mechanism, we analyzed the changes in gene expression induced by the ketogenic diet in the rat kainic acid (KA)epilepsy model. Materials and Methods: KA-administered rats were fed the ketogenic diet or a normal diet for 4 weeks, and microarray analysis was performed with their brain tissues. The effects of the ketogenic diet on cathepsin E messenger ribonucleic acid (mRNA) expression were analyzed in KA-administered and normal saline-administered groups with semi-quantitative and real-time reverse transcription polymerase chain reaction (RT-PCR). Brain tissues were dissected into 8 regions to compare differential effects of the ketogenic diet on cathepsin E mRNA expression. Immunohistochemistry with an anti-cathepsin E antibody was performed on slides of hippocampus obtained from whole brain paraffin blocks. Results: The microarray data and subsequent RT-PCR experiments showed that KA increased the mRNA expression of cathepsin E, known to be related to neuronal cell death, in most brain areas except the brain stem, and these increases of cathepsin E mRNA expression were suppressed by the ketogenic diet. The expression of cathepsin E mRNA in the control group, however, was not significantly affected by the ketogenic diet. The change in cathepsin E mRNA expression was greatest in the hippocampus. The protein level of cathepsin E in the hippocampus of KA-administered rat was elevated in immunohistochemistry and the ketogenic diet suppressed this increase. Conclusion: Our results showed that KA administration increased cathepsin E expression in the rat brain and its increase was suppressed by the ketogenic diet.

Nanoparticulate Systems for Disease Diagnosis and Therapy

정현정 한국공업화학회 2019 한국공업화학회 연구논문 초록집 Vol.2019 No.1

The application of nano- and micro-technology for healthcare has been of great interest due to its unique features as biomedical materials for therapy and diagnostics. Nanoparticle systems based on magnetic or fluorescence detection can be engineered to achieve excellent sensitivity and specificity by maximizing signal-to-noise ratios and reducing off-target binding. We introduce the application of nanoparticle systems as a rapid and simple diagnostic platform for detecting bacterial pathogens and multidrug-resistance. Secondly, we also developed a nonviral genome editing therapeutic based on nano-delivery of the CRISPR/Cas9 system. These approaches can be potentially applied in the clinic either as a rapid diagnostic platform in the bedside, or as a therapeutic that can overcome safety issues of conventional virusbased strategies.