군 방호시설에 자철석 콘크리트 적용 시 감마선 차폐효과 분석

이상규,이호찬,이건우,한다희,박영준,Lee, Sang-Kyu,Lee, Ho-Chan,Lee, Gun-Woo,Han, Da-Hee,Park, Young-Jun 한국건축시공학회 2020 한국건축시공학회지 Vol.20 No.2

핵 및 방사능전 상황에서 방사선에 의한 인명피해를 줄이기 위한 방안으로서 유개호에 자철석이 포함된 중량 콘크리트의 적용 가능성을 확인해보았다. 이에 본 연구에서는 자철광 콘크리트의 방사선 차폐효과를 분석하기 위하여 감마선원을 사용하여 차폐실험을 진행하였고 실험조건과 동일한 몬테칼로 모델링도 하였다. 그 결과 자철광의 함량이 증가할수록 감마선에 대한 차폐효과가 향상됨을 확인할 수 있었다. 향후 자철광 콘크리트가 군사적 목적의 시설물에 적용될 경우 방사선 차폐 측면에서 효과를 얻을 수 있을 것이라 기대한다. The purpose of this research is to analyze the gamma ray shielding effect of heavy concrete containing magnetic aggregate and to confirm the applicability to the military protective facilities. In general, a military concrete structure protects combatants from bullets, and also it provides some radiation shielding. In this research, experiments were conducted using a Cs-137 source to check the gamma ray shielding effect. In addition, the Monte Carlo N-Particle(MCNP) modeling was applied to evaluate the gamma ray shielding effect of a military structure. As a result, as the concrete thickness increased, the shielding performance improved according th the linear attenuation law. With that, as the ratio of magnetic aggregate was increased, gamma ray shielding performance was also improved. Therefore, this research verified that the application of magnetic aggregate concrete to military facilities for radiation shielding purposes would be useful.

논단 - 최근 우리 경제의 회복과 출구전략의 방향

이상규,Lee, Sang-Gyu 한국시멘트협회 2009 시멘트 Vol.184 No.-

흡연과 음주가 남성 암 사망에 미치는 영향: 강화 코호트 연구

이상규,남정모,이상욱,오희철,Lee, Sang-Gyu,Nam, Chung-Mo,Yi, Sang-Wook,Ohrr, Hee-Chul 대한예방의학회 2002 예방의학회지 Vol.35 No.2

Objective : To examine the relationship between cigarette smoking, alcohol and cancer mortality in men in the Kangwha cohort after 12 years and 10 months of follow up. Methods : The subjects consisted of 2,681 men in the Kangwha cohort aged over 55 in 1985. Number of deaths and the time to death front all cancers and other cause were measured and the data for the smoking and drinking habits were obtained from the baseline survey data in 1985. All subjects were categorized into four groups according to their smoking habits: non-smokers, ex-smokers, mode(ate-smokers (1-19 cigarettes per day), heavy-smokers ($\geq$20 cigarettes per day). In addition, they were also categorized according to their drinking habits: non-drinkers, light-drinkers ($\leq$1 drink per week), moderate-drinkers (<3 drinks per day), heavy-drinkers ($\geq$3 drinks per day). The cancer specific death rates were calculated according to their smoking and drinking status. The adjusted risk ratio for all cancer deaths according to their smoking and drinking status were estimated using the Cox's proportional hazard regression model. Results : Using nonsmokers as the reference category, the adjusted risk ratio for all cancer deaths were 1.573(95% CI=1.003-2.468) for heavy-smokers. For lung cancer deaths, the adjusted risk ratios were 3.540(95% CI=1.251-10.018) for moderate-smoker and 4.114(95% CI=1.275-13.271) for heavy-smokers. Compared to non-drinkers, the adjusted risk ratio for stomach cancer was 2.204(95% CI=1.114-4.361) for light-drinkers. Conclusion : Smoking is the most significant risk factor for cancer deaths particularly lung cancer.

Yucca잎의 성숙도와 알칼리 처리 농도에 따른 섬유의 수색 및 물성에 관한 연구

이상규,유덕환,이인우,Lee, Sang-Gyu,Yu, Deok-Hwan,Lee, In-U 한국섬유공학회 1991 한국섬유공학회지 Vol.28 No.7

The test samples prepared from Yucca leaf of filamentosa species, which was divided into 5 different stages of growth, was prepared by boiling and dipping treatment of the sample in thin purpose to investigate the possible utilization of Yucca cellulosics as a textile fiber. The fiber yield structure and various physical properties of the fiber treated with 6 different concetrations of NaOH (4%, 8%, 12%, 15%, 17%, 20%) after eliminating cuticle and chlorophyl, were investigated and revealed in the followings. 1. It was indicated that cellulose yield was increased with increasing stage of growth of Yucca leaf. 1 2. When fiber bundle after boiling and dipping treatment was contacted with different concentsration of alkali, the amount of cellulose yield, lignin and pentosan were decreasing, especially decreased residual pentosan was peculiar. 3. Microscopic structure showed that the single fiber of alkali treated was closely adjacent comparing to that of untreated fiber, and also showed the plain surface of it. Cellulosic fiber bundle treated with high concentration of alkali was substancially divided into single fiber. 4. X-ray diffraction showed that Yucca cellulose from Yucca cellulosics is exactly the same cellulose as the ordinary fiber cellulose. Crystallinity of cellulose, size and orientation of the crystallite were increased with increasing stage of growth of Yucca cellulosics, and reversely they were decreased with increasing concentration of alkali treatment.

거짓비늘증후군에서 안압 상승의 위험인자

이상규,백남호,Sang Kyu Lee,Nam Ho Baek 대한안과학회 2009 대한안과학회지 Vol.50 No.1

Purpose: We evaluated the short and long-term changes of intraocular pressure (IOP) and studied its risk factors in pseudoexfoliation (PEX). Methods: A total of 40 eyes that had been newly diagnosed with PEX from January 1, 1995 to December 31, 2007 were included in this study. Age, gender and accompanying systemic disease were recorded. In addition, the age, gender, number of antiglaucoma eye drops, history of cataract operation, and history of systemic disease were evaluated as risk factors for IOP elevation during the follow-up periods. Pre and post cataract operation IOP was checked to evaluate the effect of the cataract operation on IOP. Results: The risk factors for IOP elevation in patients newly diagnosed with PEX were old age and female gender. After treatment, a long follow-up period and number of eyedrops were risk factors for IOP elevation. The cataract operation had a one year IOP control effect, especially in cases where the pre operative IOP was greater than 21 mmHg. Over the long term, however, the IOP control effect of cataract surgery could not be determined. Conclusions: IOP increased as result of increased patient age. Phacoemulsification was a protective factor for IOP elevation and may be a good method for short-term IOP control.

Hepatotoxic Effect of 1-Bromopropane and its Conjugation with Glutathione in Male ICR Mice

이상규,Sang Wook Jo,Tae Won Jeon,In Hye Jun,Chun Hua Jin,Ghee Hwan Kim,Dong Ju Lee,Tae-Oh Kim,이응석,정태천 대한약학회 2005 Archives of Pharmacal Research Vol.28 No.10

The hepatotoxic effects of 1-bromopropane (1-BP) and its conjugation with glutathione were investigated in male ICR mice. A single dose (1000 mg/kg, po) of 1-BP in corn oil to mice significantly increased serum activities of alanine aminotransferase and aspartate aminotransferase. Glutathione (GSH) content was dose-dependently reduced in liver homogenates 12 h after 1-BP treatment. In addition, 1-BP treatment dose-dependently increased levels of S-propyl GSH conjugate at 12 h after treatment, as measured by liquid chromatography-electrospray ionization tandem mass spectrometry. The GSH conjugate was maximally increased in liver at 6 h after 1-BP treatment (1000 mg/kg), with a parallel depletion of hepatic GSH content. Finally, 1-BP induced the production of malondialdehyde in liver. The present results suggest that 1-BP might cause hepatotoxicity, including lipid peroxidation via the depletion of GSH, due to the formation of GSH conjugates in male ICR mice.

창간사-국제수준의 우수한 방화제품 생산을 유도

이상규,Lee, Sang-Gyu 한국화재보험협회 1987 방재기술 Vol.1 No.-

소양인(少陽人) 망음증(亡陰證) 치료(治療) 임상례(臨床例)

이상규,이의주,고병희,송일병,Lee, Sang-gyu,Lee, Eui-ju,Koh, Byung-hee,Song, Il-byung 사상체질의학회 2001 사상체질의학회지 Vol.13 No.3

Mangeum-disease is important syndrome in soyangin's pathology taking urgent diarrhea. In this case study, we diagnose one patient as mangeum-disease. She had a cold before and took a medical treatment with antibiotics. During the treatment she had a diarrhea, palpitation, arrhythmia and edema. We diagnose it as mangeum-disease. So we dose her with hyungbangjihwangtang and we had a good result-all symptoms are disappeared in two months.

웹 서비스 코레오그라피를 이용한 자동 웹 서비스 컴포지션 시스템

이상규,한상용,Lee, Sang-Kyu,Han, Sang-Yong 한국정보처리학회 2008 정보처리학회논문지D Vol.15 No.1

웹 서비스와 SOA(Service Oriented Architecture)의 확산으로 웹 서비스 컴포지션의 대한 관심도 점차 커져가고 있다. 최근에는 보다 동적이고 지능적인 SOA 환경의 구축을 위해서 자동 웹 서비스 컴포지션에 대한 연구가 활발하게 진행되고 있다. 하지만, 아직까지 자동 웹 서비스 컴포지션에 관한 완전한 해결책은 제시되지 못하고 있으며, 기존의 연구에서는 여러 가지 문제점을 드러내고 있다. 문법적인 정보 기반의 자동 컴포지션은 잘못된 의미 연결로 인하여 컴포지션의 정확성을 떨어뜨린다. 또한 대부분의 연구에서는 추상적인 컴포지션 결과를 만들어내기 때문에, 실제로 실행하기는 어려움이 있다. 본 논문에서는 이러한 문제점들을 개선하기 위하여 웹 서비스 코레오그라피 기반의 자동 웹 서비스 컴포지션 시스템을 제안하고 있다. 제안하는 시스템에서는 컴포지션의 정확성을 향상시켰고, 보다 구체적인 컴포지션 결과를 만들어낼 수 있다. Web Services composition has gained a considerable attention because of the widespread use of the Web Services and SOA. Recently, various researches on automatic Web Services composition are on going to realize more dynamic and intelligent SOA environments. However, there is no complete solution for automatic Web Services composition now and previous researches have several problems. Automatic composition based on syntactic information has low correctness through incorrect semantic linking. Moreover, many researches make an process as the result of composition which is hard for actual execution. In this paper, improved automatic Web Services composition based on Web Services choreography is proposed. In this system, the correctness is improved and the result of composition is more concrete process.

Identification of Glutathione Conjugates of 2, 3-Dibromopropene in Male ICR Mice

이상규,백서연,전태원,전인혜,김기환,진전화,Dong Ju Lee,김준규,염영나,정태천 대한약학회 2006 Archives of Pharmacal Research Vol.29 No.2

Hepatotoxic potential of 2, 3-dibromopropene (2, 3-DBPE) and its conjugation with glutathione (GSH) were investigated in male ICR mice. Treatment of mice with 20, 50, and 100 mg/kg of 2, 3-DBPE for 24 h caused elevation of serum alanine aminotransferase and aspartate aminotransferase activities. The hepatic content of GSH was not changed by 2, 3-DBPE. Meanwhile, the GSH content was slightly reduced when mice were treated with 2, 3-DBPE for 6 h and significantly increased 12 h after the treatment. Subsequently, a possible formation of GSH conjugate of 2, 3-DBPE was investigated in vivo. After the animals were treated orally with 20, 50, and 100 mg/kg of 2, 3-DBPE, the animals were subjected to necropsy 6, 12, and 24 h later. A conjugate of S-2-bromopropenyl GSH was identified in liver and serum treated with 100 mg/kg of 2, 3-DBPE by using liquid chromatography-electrospray ionization tandem mass spectrometry. The protonated molecular ions [M+H]+ of S-2-bromopropenyl GSH were observed at m/z 425.9 and 428.1 in the positive ESI spectrum with a retention time of 6.35 and 6.39 min, respectively. In a time-course study in livers following an oral treatment of mice with 100 mg/kg of 2, 3-DBPE for 6, 12, and 24 h, the 2, 3-DBPE GSH conjugate was detected maximally 6 h after the treatment. The present results suggested that 2, 3-DBPE-induced hepatotoxicity might be related with the production of its GSH conjugate.