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      • 몰입(Flow)이론을 적용한 진로상담에 관한 연구

        윤영란 ( Young Ran Yoon ) 상명대학교 인문과학연구소 2006 人文科學硏究 Vol.18 No.-

        The purpose of this study is to purpose a career counseling model based on the theory of ``Flow``. The study was originally developed from various research about the unique experience of creative people. However. many researchers apply this theory to research and practice regarding sports psychology, adolescents` development, and counseling/psychotherapy. The study explores a way to apply ``Flow`` theory to career counseling theory and practice. This study describes uniqueness of career counseling from the perspective of ``Flow`` theory: ① work could be a source of joy, ② the goal of career counseling should be expanded from adaptation to a job to the development of people`s potential and talent, ③ career problem is a lack of ``everyday Flow experience``, ④ the task of career counseling is not limited to career choice but to help experience ``flow`` and integrate it to personal life goal.

      • 진로집단상담이 대학생들의 진로결정 자기효능감에 미치는 영향

        윤영란 ( Yoon Young-ran ) 인하대학교 교육연구소 2008 교육문화연구 Vol.14 No.2

        본 연구는 대학 내 진로지도를 활성화하려는 목적으로 진로집단상담을 활용하여 집단상담의 효과를 검증하고 검증된 결과들을 바탕으로 대학생 진로지도의 방안을 제시하고자 한다. 연구의 대상은 서울 소재 S 대학교 1-4학년 학생 22명으로 집단상담은 두 집단으로 나누어 각각 10명과 12명이다. 진로지도의 효과는 진로결정 자기효능감을 선정해 사용하였다. 그리고 이러한 효과 검증으로 밝혀진 결과들로 대학생 진로지도의 방안을 제시해 보았다. 연구의 주요 결과는 다음과 같다. 대학 내 진로 집단상담으로 진로지도를 받은 학생들의 진로결정 자기효능감이 향상되었다. 진로집단상담으로 진로지도를 받은 학생들은 자신을 더 잘 이해하게 되었고 직업에 대해서도 더 잘 알게 되었다. 그리고 진로 전반에 대한 자신감도 향상되었다. 이러한 결과들을 바탕으로 대학생 진로지도의 방안을 제시하면 다음과 같다. 진로는 매우 개별적인 문제이므로, 개인이 가지고 있는 진로문제와 진로 이외의 문제들로의 접근은 상담으로 도움을 줄 수 있어야 할 것이다. 자신을 더 정확하게 이해하고자 하는 학생들이나 전공과 적성이 불일치하다고 생각하는 학생, 의사결정능력이나 취업과 관련하여 불안과 스트레스를 받는 학생들에게는 개인상담이나 집단상담으로 도움을 줄 수 있어야 하겠다. The purpose of this research is to utilize the career group counselling approach to revitalize the career guidance in college. The subjects of this particular study were make up total population of 22 people. The measuring instruments used that career decision-making self-efficacy short form developed by Betz(l983), Through the career group counselling, as career-guidance plan of the college students, I studied the possibility to build the career plans, the management ability, understanding and search of the job, and self-understanding. Based upon proven outcome of this research, I laid out the plans and the models of the career-guidance for college students. The study results are as follows. Students who took 'career group counselling' class were remarkably improved in the career decision-making self-efficacys. All the career-guidance process should be planned and then managed only after oneself deeply understand about him/herself and his/her job. The personal or group counselling method should be applied to help the student group, who wants to learn and understand more about themselves and who feel insecure about irrelevancy in between their major and aptitude result and lastly who were experiencing the instability and under lots of stress in regards to decision making ability and employment.

      • KCI등재

        한국인의 Cytochrome P450 2C19 유전형 분석

        윤영란,이준호,김문경,손지홍,이상섭,김종신,이순용,차인준,신재국,Yoon, Young-Ran,Lee, Jun-Ho,Kim, Moon-Kyung,Shon, Ji-Hong,Lee, Sang-Seop,Kim, Jong-Shin,Lee, Soon-Yong,Cha, In-June,Shin, Jae-Gook 대한임상약리학회 2002 臨床藥理學會誌 Vol.10 No.1

        배경 : 간 cytochrome P450 2C19 (CYP2C19) 효소군은 유전적 다형성을 나타내는 대표적인 약물대사효소의 하나로, 본 연구에서는 다수의 한국인에서 CYP2C19 유전자 변이를 분석하고, 이들 변이 allele들의 출현빈도를 타 종족에서의 결과와 비교 분석하였다. 방법 : 282 명의 건강한 한국인 피험자에서 CYP2C19 (*2와 *3) allele 변이를 polymerase chain reaction restriction fragment length polymorphism (PCR­RFLP) 방법을 이용하여 분석하였다. 결 과 : 282명의 한국인 피험자 CYP2C19*1/*1 (41.8%), CYP2C19*1/*2 (35.5%), 및 CYP2C19*1/*3 (8.5%) allele 변이를 가지는 extensive metabolizer(EM)는 총 242명으로 나타났다. 40명 (14.2%)은 CYP2C19 의 poor metabolizer(PM)로 밝혀졌는데, 이들의 allele 빈도는 CYP2C19*2/*2, CYP2C19&2/*3, 및 CYP2C19*3/*3 가 각각 8.9%, 3.9%, 1.4% 로 나타 났다. 또한, 총 564개 allele에서 각 allele의 출현빈도는 CYP2C19*1, CYP2C19*2, 및 CYP2C19*3가 각각 63.8%, 28.6% 및 7.6%로 나타났다. 결 론 : 한국인의 CYP2C19 PM 유전형의 빈도는 중국인, 일본인 등의 동아시아인보다 다소 낮았으나, 이는 서양인에 비해서는 유의하게 높은 것으로 나타났다. Background : The cytochrome P450 2C19 (CYP2C19) is a well known microsomal oxidizing enzyme showing genetic polymorphism. We extensively evaluated the frequency distribution of the CYP2C19 allelic variants in a Korean population and compared to those of other ethnics. Methods : Genotyping of CYP2C19 (*2 and *3) was carried out in a total of 282 unrelated Korean subjects. CYP2C19 genotypes were determined using polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP). Results : Two hundred forty two of 282 Korean subjects, carried extensive metabolizer(EM) genotypes including CYP2C19*1/*1 (41.8%), CYP2C19*1/*2 (35.5%), and CYP2C19*1/*3 (8.5%), respectively. Forty subjects (14.2%) were identified to have CYP2C19 poor metabolizer(PM) genotype, and the frequencies of CYP2C19*2/*2, CYP2C19&2/*3, and CYP2C19*3/*3 were 8.9%, 3.9%, 1.4% respectively. The allele frequencies of CYP2C19*1, CYP2C19*2, and CYP2C19*3 among 564 alleles evaluated were 63.8%, 28.6% and 7.6%, respectively. Conclusions : These results suggest that frequency of CYP2C19 PM genotypes is slightly lower than that of other East Asians including Chinese and Japanese, but significantly higher than Caucasian.

      • 친환경 건축 자재에서의 온도 변화에 따른 곰팡이 발아 및 성장에 관한 실험 연구

        윤영란(Yoon Young-Ran),문현준(Moon Hyeun-Jun),박진우(Park Jin-Woo) 대한건축학회 2007 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.27 No.1

        Recently, new building materials have been developed to response Sick Building Syndrome(SBS). These new materials are recognized as environment-friendly building materials, since they are able to reduce emission of harmful chemical gases, such as Volatile Organic Compounds and Formaldehyde by using natural/organic materials. However, the risk of mold growth on these materials may increases due to nutrients in the new materials. In order to understand mold phenomenon correctly, the relationship between mold germination (or mold growth rate) and components of building materials should be established. This study shows the relationships among temperature, mold germination, and growth on wall papers and building materials. The experimental study reveals that environmental-friendly building materials can facilitate mold germination and growth.

      • KCI등재

        클러스터링 기반 건물 용도별 에너지 소비 패턴 분석

        윤영란(Young-Ran Yoon),신상헌(Sang-Heon Shin),문현준(Hyeun-Jun Moon) 한국생활환경학회 2017 한국생활환경학회지 Vol.24 No.2

        The analysis of energy use patterns is considered to be one of the important building energy performance evaluation, because it can improve the understanding of energy consumption characteristics of building. Pattern analysis can also be used for benchmarking with other buildings. In this study, we analyzed the building energy consumption patterns based on the energy consumption data from building energy management system(BEMS) using machine learning techniques, especially k-means clustering. Energy consumption data were collected from 8 buildings with different building usage for one year. As a result, the office type buildings (A, B, D, E) showed different characteristics in seasons, weekday and holiday, etc according to the number k. The residential building (C) showed no significant difference in the weekday and weekday, but was more sensitive to seasonal changes. The buildings that operate 24 hours, such as F(Police station), G(Fire station), showed similar energy use patterns on weekdays and weekends. The school building (H) was divided into 11 clusters according to weekdays and holidays. Clustering based on building energy consumption could reveal different energy patterns and characteristics according to building operation, and the results were not always match to the nominal building usage.

      • KCI등재

        입주세대별 에너지 사용 요인 기반 가우시안 프로세스 예측 모델 개발

        윤영란(Yoon, Young Ran),문현준(Moon, Hyeun Jun) 한국건축친환경설비학회 2016 한국건축친환경설비학회 논문집 Vol.10 No.2

        Forecasting of energy consumption in buildings is crucial for energy efficient control in the operation stage. By using multi-variate approach in energy performance prediction, we can characterize building energy usage with a few available variables. The selection of variables in the prediction model is important for an accurate evaluation. However, very few studies have applied the variables related to building operation for prediction of energy consumption in buildings. So, in this study we propose a prediction model using energy use factors: occupant schedule data, operation data, equipment data to remove the impact of other variables on building performance; climate, usage and building envelope. This study reports the prediction model to estimated in January electricity consumption of each tenant in office buildings by using Gaussian process (GP) model. Analyses were performed with 26 variables related on building operation for 1,027 tenants in 13 offices in Seoul. The results show that the GP model using variables related to operation provides an accurate prediction and a low error. This study also established a method to identify a combination of variables that could make a more accurate estimation of energy consumption.

      • KCI등재

        시간 단위의 M&V 베이스라인 구축을 위한 머신러닝 알고리즘 기반 건물에너지 예측 모델의 성능 비교

        윤영란(Young Ran Yoon),이명훈(Myeung Hun Lee),문현준(Hyeun Jun Moon) 한국생활환경학회 2018 한국생활환경학회지 Vol.25 No.5

        As an alternative to existing simple regression monthly baseline method, we developed an hourly baseline model for M&V based on prediction models with machine learning techniques. This paper evaluated three data-driven energy models used to predict building electricity energy consumption: K-nearest neighbor (KNN) model, Random Forest (RF) model, and Artificial Neural Network (ANN) Model. As a result, CVRMSE is about 10% in all three models. In addition, it was confirmed that the ANN is superior to the KNN or RF in terms of the prediction accuracy of the energy consumption pattern in which the energy consumption is rapidly fluctuated with time.

      • KCI등재후보

        상부 위장관 증세가 있는 소아의 위십이지장병변 및 Helicobacter pylori 감염

        윤영란,김미령,임재영,최명범,박찬후,우향옥,희상,고경혁,강형련,백승철,이우곤,조명제,이광호,Yoon, Young-Ran,Kim, Mi-Ryeung,Lim, Jae-Young,Choi, Myoung-Bum,Park, Chan-Hoo,Woo, Hyang-Ok,Youn, Hee-Shang,Ko, Gyung-Hyuck,Kang, Hyung-Lyun,Baik, S 대한소아소화기영양학회 2003 Pediatric gastroenterology, hepatology & nutrition Vol.6 No.2

        목 적: 만성 반복성 복통, 식사 후 상복부 불쾌감, 잦은 구토나 구역질이 있는 소아를 대상으로 위내시경을 시행하여 위십이지장 병변을 확인하고, 생검체를 이용한 위십이지장 조직학적 검사와 H. pylori 검출 그리고 면역블롯팅을 통해 혈청 내에 H. pylori 특이 항체 존재를 확인하여 한국에서 관찰되는 소아의 위장관 증세와 위십이지장병변 및 H. pylori 감염과의 관계를 조사하고자 하였다. 방 법: 1990년 6월부터 1991년 4월까지 경상대학교병원 소아과에서 상부 위장관 증상으로 위내시경을 시행 받은 184명 중 위 전정부에서 생검이되었고, 요소분해효소 검사, Warthin-Starry 은염색 혹은 Hematoxylin-Eosin 염색으로 조직학적에서 H. pylori의 존재유무를 확인할 수 있었던 107명을 대상으로 위십이지장 조직학적 검사와 IgG 면역블롯팅에 의한 항-H. pylori 항체 보유 유무를 확인하였다. 결 과: 1) 대상 환아 107명 중 남아가 61명(57%), 여아가 46명(43%)이었으며, 연령은 2세부터 15세까지 분포하였고 평균연령은 10.7세로서 10세에서 15세 사이가 가장 많았다. 2) 내시경상 15%에서 위출혈 반점, 위궤양, 십이지장궤양, 십이지장 미란, 출혈성 십이지장염 등이 관찰되었고 대부분은 다양한 정도의 위점막 발적이 관찰되었다. 3) 107명 중 94명(88%)에서 경도 이상의 조직학적 만성위염이 있었으며, 십이지장 조직이 검사 가능하였던 99명 전원에서 만성십이지장염이 있었다. 4) 요소분해효소 검사는 위에서는 45%, 십이지장에서는 25.6%에서 양성으로 판정되었다. H&E 염색 검사에서 38.7%, Warthin-Starry 은염색 검사에서는 40%에서 HPLO 양성이었다. 이 세가지 검사 중 1개 검사에서 양성인 경우인 조직학적 H. pylori 양성은 57%이었다. 5) IgG 면역블롯팅 양성은 96%이었다. 6) 연령군별 조직학적 H. pylori 양성은 0∼4세 군에서는 29%, 5∼9세 군에서는 41%, 10∼15세 군에서는 68%로 연령이 증가할수록 양성률이 증가하였으나, 조직학적 만성위염 및 만성십이지장염 빈도와 면역블롯 양성 빈도는 연령군별 차이가 없이 높은 양성률을 유지하였다. 결 론: 상부 위장관 증세가 있는 소아의 대부분은 조직학적 만성위염 및 만성십이지장염과 동시에 H. pylori에 대한 특이 IgG 항체를 보유하고 있었다. Purpose: This study was undertaken to evaluate the gastroduodenal pathology and Helicobacter pylori infection in children with upper gastrointestinal symptoms. Methods: One hundred and seven pediatric patients with upper gastrointestinal symptoms were undergone endoscopy at the Gyeongsang National University Hospital from June 1990 to April 1991. Histopathologic examination was done by H & E staining of gastric antral biopsy specimen and gastritis was defined according to the Sydney System. Tissue H. pylori status was evaluated with the urease test using Christensen's urea broth and H & E or Warthin-Starry silver staining of gastric antral biopsy specimen. IgG Immunoblotting were also performed to detect specific anti-H. pylori antibody in these patients. Results: The reasons for endoscopy were recurrent abdominal pain, acute abdominal pain, sallow face, hunger pain, and frequent nausea. Variable degrees of gastric mucosal hyperemia were found in most of the patients. Gastric hemorrhagic spots, gastric ulcer, duodenal ulcer, duodenal erosion, and hemorrhagic duodenitis were rare endoscopic findings. Histologic chronic gastritis was found in 88% of 107 patients. Histologic chronic duodenitis was observed in all 99 patients whose tissue were available. Gastric tissue H. pylori was positive in 57% of 107 patients by one of the ureasetest, H & E staining and Warthin-Starry silver staining. However, gastric tissue H. pylori detection rate was lower in the younger age groups. Anti-H. pylori IgG antibodies were detectable in 96% of 107 patients. Conclusion: Chronic gastroduodenitis and anti-H. pylori IgG antibody were ubiquitous in children with upper gastrointestinal symptoms.

      • KCI등재

        적정약물요법을 위한 TDM의 임상적 응용

        윤영란,임영채,Yoon, Young-Ran,Lim, Young-Chai 대한임상약리학회 2000 臨床藥理學會誌 Vol.8 No.1

        Therapeutic drug monitoring (TDM) among various fields of clinical pharmacology plays the vital role in order to achieve the indivisualization of optimal drug therapy, which is the process of maximizing therapeutic effects and minimizing side effecs, simultaneously. Variable drug responses are largely due to the individual pharmacokinetic variations. Therefore in TDM it is very important to keep optimal drug concentrations, which makes it possible to optimize the clinical outcomes of each patient. In recent, the introduction of clinical pharmacokinetic principles and development of assay methods makes TDM more prevalent. This article describes the clinical significance, functions, and applications of TDM in several aspects. TDM indications, concepts and examples of therapeutic range are also described. The features which should be strived for in each step of TDM process (the decision to request a drug level, blood sampling, laboratory measurement, clinical interpretation of drug concentration, and production of individualized dosage regimen and dosage adjustment) are discussed.

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