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유영조(Yoo, Young-Jo),김명호(Kim, Myung Ho) 한국산학기술학회 2014 한국산학기술학회논문지 Vol.15 No.1
본 논문에서는 3가지 음원의 a지수가 피험자에게 미치는 영향과 피험자의 안정성, 집중력 및 생산성을 향상 시킬 수 있는 최적의 음원의 a지수를 찾기 위한 연구를 하였다. 피험자는 건강상태를 점검하여 남자 5명과 여자 5명의 대학생 10명 으로 선별하였고 실험기간은 약 2달간 진행되었다. 뇌파(EEG), 심박동변이(HRV) 및 진동이미지를 측정하여 안정성, 집중력, 스트레스 및 심장박동의 변화를 분석하였다. 온도 25[℃], 상대습도 50[%], 조도 1.000[lux] 및 기류속도 0.02[m/sec]의 인공기후 실 에서 음원의 a지수 a=1.106, a=1.749 및 a=2.227의 음원을 이용하여 측정하였다. 연구결과 a=1.106에서 음원에 노출되기 전 에 비하여 상대 Sα파, 상대 ??및 상대 활성화 되었으며 비대칭지수, 스트레스지수 및 심박변이도는 감소하였다. 따라서 변동리듬 a=1.106의 음원이 안정성, 집중력 및 생산성 향상과 스트레스 감소에 가장 효과적인 것을 알 수 있었다. In this study, have researched ‘a' index from three sound sources, effects on subject and finding optimal ‘a' index, which can improve subject's stability, concentration and productivity. Check the health status of subjects who were selected 5 male and 5 female university students, and the period of this experiment was about two months. It were measured each subject's EEG, HRV and vibra image to analyze transition of stability, concentration, stress and heart beat. The results was measured in an environmental test room of temperature 25 [℃], the relative humidity 50 [%], illuminance 1,000 [lux] and air current speed 0.02[m/sec] with 'a' index of three sound sources which are a=1.106, a=1.749 and a=2.227. Results in a = 1.106 compared to before exposure, relative Sα wave, relative ??wave and relative 桃?wave have been revitalized, asymmetry index, stress and HRV have been decreased. Thus, to increase stability, concentration and productivity, also to decrease stress, changes in sound source of a=1.106 was found to be the most effective.
유영조(Young-Jo Yoo),김정민(Jung-Min Kim),김명호(Myung-Ho Kim),김종민(Jong-Min Kim) 한국산학기술학회 2014 한국산학기술학회 학술대회 Vol.- No.-
본 논문에서는 3가지 음원의 a지수가 피험자에게 미치는 영향과 피험자의 안정성, 집중력 및 생산성을 향상 시킬 수 있는 최적의 음원의 a지수를 찾기 위한 연구를 하였다. 피험자는 건강상태를 점검하여 남자 5명과 여자 5명의 대학생 10명으로 선별하였고 실험기간은 약 2달간 진행되었다. 뇌파(EEG), 심박동변이(HRV) 및 진동이미지를 측정하여 안정성, 집중력, 스트레스 및 심장박동의 변화를 분석하였다. 온도 25[℃], 상대습도 50[%], 조도 1.000[lux] 및 기류속도 0.02[m/sec]의 인공기후실 에서 음원의 a지수 a=1.106, a=1.749 및 a=2.227 의 음원을 이용하여 측정하였다. 연구결과 a=1.106에서 음원에 노출되기 전에 비하여 상대 Sα파, 상대 및 상대 파가 활성화 되었으며 비대칭지수, 스트레스지수 및 심박변이도는 감소하였다. 따라서 변동리듬 a=1.106의 음원이 안정성, 집중력 및 생산성 향상과 스트레스 감소에 가장 효과적인 것을 알 수 있었다.
만성 간 질환에서 Thallium-201 간 스캔의 단락지수(Shunt Index)와 간 조직 검사 소견에 대한 연구
유영조(Young Jo Yoo),정진웅(Jin Woong Jung),최춘식(Choon Sik Choi),전대원(Dae Won Jeon),이오영(Oh Young Lee),최호순(Ho Soon Choi),윤병철(Byung Chul Yoon),함준수(Joon Soo Hahm),이민호(Min Ho Lee),최윤영(Yun Young Choi),홍은경(Eun Kyun 대한내과학회 2000 대한내과학회지 Vol.58 No.2
N/A Background : The disturbances of portal circulation in chronic liver disease may cause hepatic failure, hepatic encephalopathy and variceal bleeding. The measure of porto-systemic shunt plays a significant role in the management and prognosis of the patients. So we have evaluated the relationship between the shunt index of thallium-201 liver scan and the histological grade and stage of chronic liver disease. Methods : The thallium-201 scintigraphy per rectum was evaluated in 159 patients with chronic liver disease, which were proven with percutaneous liver biopsy. We used the heart to liver activity ratio at 20 minute as shunt index, representing portal-systemic shunt. The two pathologists scored independently hepatitis activity (lobular and porto-periportal activity) and stage (fibrosis). Results : A significant difference was noted between the shunt index and the scores of fibrosis (p<0.001) although this correlation was statistically weak (r=0.26, p=0.008). In cumulative logistic regression test, the shunt index had a effect on the fibrosis (p<0.001) but not on the lobular and porto-periportal activity. Fibrosis was predicted as less than 2 if shunt index was less than 0.24, 3 if more than 0.24 but less than 0.46, 4 if more than 0.46. Conclusion : The shunt index of thallium-201 liver scintigraphy correlated only with fibrosis not with lobular and porto-periportal activity. As the fibrosis progresses in chronic liver disease, portal hypertension becomes more severe and the shunt index increases. Thallium-201 liver scan may be useful for evaluation of hepatic fibrosis instead of invasive liver biopsy in predicting the histological stage (fibrosis) of advanced chronic liver disease.(Korean J Med 58:152-160, 2000)
키토산분해효소를 생산 분비하는 Bacillus sp . P16의 선발 및 특성
박노동,정미라,조유영,지연태 ( Ro Dong Park,Mi Ra Jung,Yoo Young Jo,Yeon Tae Chi ) 한국응용생명화학회 1997 Applied Biological Chemistry (Appl Biol Chem) Vol.40 No.5
An endochitosanase-producing bacterium was isolated from soil and identified as a strain of Bacillus sp. The isolate was gram positive, rod shape (0.4-0.6×1.6-2.2 ㎛), endospore-forming, catalase positive, and mobility positive, and grown at pH 4.5-11.0 and upto 42℃ in the medium containing 2% NaCl. RAPD analysis of the DNA purified from the strain was also performed, and the chitosanase-producing strain was named as Bacillus sp. P16. The culture supernatant of the strain showed strong liquefaction activity and rapidly decreased viscosity of chitosan solution. By TLC and HPLC, chitooligosaccharides of DP 2-7 were separated and identified from the enzyme hydrolyzates of chitosan. The chitosanase from Bacillus sp. P16 was thus regarded as an endo-splitting type.
Trimethoprim / Sulfamethoxazole ( TMP / SMX ) 을 복용 중인 외래 환자에서 발생하는 경구 칼륨 투여 후 칼륨 대사 장애
최춘식(Chun Sik Choi),유영조(Young Jo Yoo),김태영(Tae Young Kim),민경환(Kyung Hwan Min),한상웅(Sang Woong Han),노광호(Kwang Ho Roh),양성규(Seong Kyu Yang),유준호(Jun Ho Yoo),오석중(Suk Joong Oh),문중돈(Jung Don Mun),김호중(Ho Jung Ki 대한내과학회 1999 대한내과학회지 Vol.57 No.1
N/A TMP/SMX has been shown to cause hyperkalemia in a few outpatients on standard-dose. This prospective study was aimed at investigating other associated factors inducing clinically important hyperkalemia in outpatients on standard-dose of TMP/SMX. Methods : Age-matched diabetic(n=22) and non-diabetic (n=20) patients with UTI on standard dose of TMP/SMX for 5 days were given acute oral intake of 40 mEq of potassium chloride(KCl). Results : Before the intake of TMP/SMX, basal levels of serum potassium(K), serum BUN and creatinine, plasma renin activity(PRA), aldosterone(PA), and transtubular potassium gradient(TTKG) were comparable between diabetic and non-diabetic subjects. Also after TMP/SMX was taken, all parameters didnt reveal any overt changes except a slightly increased serum K but not significantly (from 4.20±0.15 to 4.14±0.21mEq/L in non-diabetics; from 4.13±0.18 to 4.25±0.13mEq/L in diabetics). Following acute oral KCl load, however, the peak increases of serum K changes were significantly higher in diabetics compared to non-diabetics(0.34 0.06 vs 0.62 0.09mEq/L, p<0.01). Furthermore, 8 out of 22 diabetics but none of non-diabetics after acute KCl load developed hyperkalemia(> 5.0 mEq/L). After KCl load, PRA did not show any significant changes, whereas PA was increased simultaneously with the increments of serum K in both diabetic subgroups hyperkalemic(n=8) and normokalemic (n=14) diabetics. But increment was blunted in hyperkalemic diabetic subgroup. TTKG was increased prominently in normokalemic diabetic subgroup(9.20 from 4.50), while it was slightly increased in hyperkalemic diabetic subgroup(4.63 from 3.79mEq/L). There was statistical difference between two subgroups(p < 0.05). In conclusion, Besides the known effect of blocking sodium channels in distal K secreting cells by TMP/SMX, insulinopenia(DM). Hypoaldosteronism with its decreased tubular bioactivity, and increased exogenous K intake in concert could cause clinically overt hyperkalemia on standard-dose of TMP/SMX. When standard- dose of TMP/SMX is administered to patients with deranged K homeostasis, especially to diabetics with hypoaldosteronism, blood K level should be monitored meticulously to avoid hyperkalemia.
김정민(Jong-Min Kim),김종민(Jong-Min Kim),유영조(Young-Jo Yoo),김명호(Myung-Ho Kim) 대한설비공학회 2013 대한설비공학회 학술발표대회논문집 Vol.2013 No.6
In this study, the three type of scent and sound effects on subjects due to EEG type, and it researched to find optimal scent and sound to increase their amenity and productivity. The result of this study,SEF50 was revitalized and α wave asymmetry index has come close to "0" at U type sound and Jasmine scent. Also stress index and HRT were decreased at Z type sound and Jasmine scent. Therefore U type sound and Jasmine scent are very effective to increase amenity, productivity and concentration, and Z type sound and Jasmine scent are very effective to decrease stress.
정미라,조유영,지연태,박노동 한국키틴키토산학회 1998 한국키틴키토산학회지 Vol.3 No.1
In order to obtain microbial endochitosanases for enzymatic production of high dp chitooligosaccharides from chitosan we screended 9 microbes which showed high chitinolytic activities. We tested the chitosanase activities of total 32 enzymes including 23 commercial enzymes and 9 crude enzymes produced by the microbes, in terms of the decreases in turbidity and viscosity of chitosan solution, the amount of pecipitation after neutralization, and reducing sugar-producing activity, after incubation with each enzyme. We selected Bacillus spp. P20, P21, and P30 as potential sources for production of endochitosanases to produce high dp chitooligosaccharides. Among them, enzyme produced by P2l was most potent and comparable to commercial enzyme E7. The culture supernatant of the strain P2l showed strong liquefaction activity and rapid decrease in viscosity of chitosan solution. By TLC and HPLC, chitooligosaccharides of dp 2-7 were separated and identified from the enzyme hydrolyzates of chitosn. The chitosanase from Bacillus sp. P2l was thus regarded as an endo-splitting and applicable to enzymatic production of high dp chitooligasaccharides from chitosan.