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      • 성폭력 피해아동 어머니들의 심리적 특성

        오수정(Su-Jung Oh) 대한사회정신의학회 2012 사회정신의학 Vol.17 No.1

        목 적 : 성폭력 피해 아동 어머니 중, 본인의 과거 성폭력 피해와 자녀의 친족 성폭력 피해 경험 유무에 따라 어떠한 심리적 특성을 보이 는지 MMPI-2를 통해 살펴보고자 한다. 방 법 : 성폭력 피해가 확인된 여아를 둔 어머니 67명을 대상으로, MMPI-2를 시행하였으며, 본인의 과거 성폭력 피해와 자녀의 친족 성폭력 경험 유무에 대한 차이검증을 하였다. 결 과 : 성폭력 유경험 어머니 집단은 무경험 집단에 비해 MMPI-2의 임상척도에서 Hy(히스테리), Pa(편집증), Pt(강박증), Sc(정신분열증), Hs(건강염려증), Pd(반사회성), Si(내향성)척도가 유의하게 높은 점수를 나타냈다(p<.01, p<.05). 자녀의 가해자가 친족인 어머니 집단은 가해자가 비친족인 어머니 집단에 비해 MMPI-2의 임상척도에서 Pa(편집증), Si(사회적 내향성)척도가 유의하게 높은 점수를 보였다(p<.01, p<.05). 결 론 : 어머니가 과거 성폭력 피해 경험이 있을수록, 자녀의 가해자가 친족일수록 불안, 공포, 적대감 등 정서적 불안정과 피해의식, 불신이 유의하게 높은 것으로 나타났다. Objectives : This study was conducted to investigate psychological characteristics of mothers who had sexually abused children by MMPI-2. Methods : The research packet was administerd to 67 mothers who had sexually abused children: MMPI-2. We divided groups based on the fact whether the mothers had been sexually abused or not (Group 1, Group 2), and sex offender who sexually abuse children is incest or not (Group3, Group4). T-test was performed to find differences of groups. Results : Group 1 (Mothers who had been sexually abused) was significantly higher Hy (Hysteria), Pa (Paranoia), Pt (Psychas-thenia), Sc (Schizophrenia), Hs (Hypochondriasis), Pd (Psychopathic Deviate), Si (Social Introversion) scale than Group 2, which means that Group1 experienced more anxiety, fear, hostility, and victim mentality than Group 2. Group 3 (Mothers whose child was sexually abused by incest) showed significantly higher Pa (Paranoia), Si (Social Introversion) scale than Group4, which means that Group3 had more distrust, irritability, and avoidance than Group 4. Conclusion : Mothers who had been sexually abused and Mothers whose child was sexually abused by incest have more psychological symptoms.

      • KCI등재

        조선 초기 제주 통치 체제 고찰

        오수정(Oh Su-jung) 제주학회 2018 濟州島硏究 Vol.50 No.-

        Chosun s degree of recognition in incorporating Jeju to the nation s system of counties and prefectures was in placating the faction of Horse supervision and Local supervision. The first thing the dispatched regional administrator did was to manage and dismantle Toghan(土官), who was the top custodian and the regional powerhouse. The process of altering and dissolving the title of Sungju-Prince, pay cuts, supervision and management by the KyungJaeso(京在所) was done over 50 years. Redistribution of people who made their living killing horses and cows and selling their hides to Pyongan province also served as a cause in weakening the influence of Toghan(土官) In the context of the military, the management of horses and the overhaul of defense policies served as the basis for national defense capabilities. The incorporation of horse rearing centered around Toghan into the hands of the Local government dispatched from the federal government served to solidify a structured governance which included, for instance, taxing the horse rearing. The geographical importance of Jeju was emphasized during the period of frequent invasions by Waegu(倭寇) in the King Sejong the Great era, which In response, fueled the formation of a military registry, the maintenance of Field Wall(밭담), and the reshuffling of Toghan as military personnel. Socially, this caused the incorporation of the citizens of Jeju to Confucianism evident by the establishment of schools and people paying respects to the god of Halla Mountain. Measurement of lands and plans for taxes were established as well. In conclusion, Jeju became a part of Chosun through the weakening power of Toghan, management of horse rearing by a local administrator(守令) as a mean of offering the federal government a local product during the 59 years stretched from the founding of Chosun and the era of the King Sejong the Great era. 조선의 군현제도에 편입하기 위해 제주를 인식했던 주요 요인은 馬政과 土官세력 懷柔였다. 제주에 수령을 파견하여 가장 먼저 시행한 것은 마정의 최고 관리인이자 지역의 토착세력이었던 토관에 대한 관리방안과 해체방안으로서 星主·王子職을 변경·해체하고 奉足삭감, 京在所 규찰 등 50여년에 걸쳐 이루어졌다. 또한 제주도민 중 牛馬 盜殺과 牛馬皮를 팔아 생계를 유지했던 사람들을 대거 평안도로 분치시키고 있어 이 역시 토관세력들의 지휘권을 약화 시기는 요인이 되었다. 군사적으로는 마정과 군사적 제도개편을 통해 關防시설이 구축된다. 토관 중심의 마장 관리를 牧使의 관리 하에 편입되면서 養馬를 공부의 대상으로 산정하는 등 체계적인 통치구조가 갖추어진다. 특히 세종대에는 왜구의 침입이 빈번해짐에 따라 제주가 지정학적 중요성이 부각되었고, 왜구 침입에 대비한 軍籍 작성, 밭담 정비, 토관들에 대한 軍丁의 改定 등이 이루어졌다. 사회적으로는 鄕校 설치와 漢拏山神祭 거행 등 제주도민들을 유교적 정치질서 속에 편입시키고 있다. 그 외에 조세제도 개편과 함께 토지측량작업, 조세징수에 대한 계획이 세워진다. 이런 결과를 볼 때, 조선건국에서 세종대까지 59년 동안 제주는 토관세력의 쇠퇴와 약화, 마정을 수령에 의한 진상 국마로서 관리되면서 제주는 조선의 군현체제 안에 포함되었다.

      • 일상생활기술척도-16의 타당화 연구

        배안(An Bae),오수정(Su-Jung Oh),신정(Jeong Shin) 대한사회정신의학회 2011 사회정신의학 Vol.16 No.1

        목 적 : 지역사회 내에서의 생존과 적응에 영향을 미치는, 기능적인 측면을 측정하는 일상생활기술척도 단축형의 타당화 연구이다. 방 법 : 16개 문항으로 구성된 원저의 문항을 번역-역번역의 과정을 거쳐 한국어판으로 제작하였다. 정신과 환자 205명을 대상으로, 일상생활기술척도 단축형(LSP-16), 간이정신평가척도(BPRS)를 함께 시행하였으며, 자료분석은 척도의 내적 일관성 계수 및 문항-총점간 상관, 검사-재검사, 평가자간 신뢰도를 산출하고, 탐색적 요인분석을 하였다. 결 과 : LSP-16 문항 전체의 신뢰도 계수 및 원저에 따른 하위요인별 내적 일치도, 문항과 총점간의 상관 분석 등에서 안정적인 내적 일관성을 볼 수 있었다. 또한 검사-재검사 신뢰도 및 평정자간 신뢰도도 높은 일치도를 보였다. 탐색적 요인분석 결과, LSP-16은 4개의 하위 요인으로 구성되었으며, BPRS의 문항과 유의한 상관을 보였다. 결 론 : 일상생활기술척도 단축형의 신뢰도와 타당도가 입증되었으며, 본 연구의 의의와 제한점, 앞으로의 연구과제 등이 논의되었다. Objective : This study was conducted to verify the reliability and validity for LSP-16 focused on aspect of functioning affect to surviving and adaptation in community.. Method : The original scale composed by 16 items has produced Korean version with translated-reverse translated process. The research packet was administerd to 205 psychiatric patients: LSP-16, BPRS. LSP-16's reliability was tested by internal consistency, item-total correlation, test-retest, and inter-rater. Its validity was tested by factor analysis. Results : We found that there are stable internal consistency of whole LSP-16 items and significant correlations between each items and total score. And test-retest reliability was statistically significant, and inter-rater reliability was highly consistency for 15 cases by 4 raters. The exploratory factor analysis revealed that LSP-16 had 4 factors. In the correlations between subscales of LSP-16 and each items of BPRS is significant. Conclusions : These results offer the reliability and validity for LSP-16. The implications and limitations of this study were discussed, and future directions of study were suggested.

      • KCI등재

        세안교육 프로그램이 여중생의 피부관리실천행위에 미치는 효과

        이은숙 ( Eun Suk Lee ),오수정 ( Su Jung Oh ),강수경 ( Su Kyung Kang ) 한국미용학회 2009 한국미용학회지 Vol.15 No.3

        This study was attempted to find out effects of cleansing education program applied to middle school students on skin care practice behavior, cleansing related knowledge. Objects of the study were 38 girl students of W middle school located in Gwangju metropolitan city and it was carried out between June 21, 2008 and July 16, 2008. cleansing education program was conducted one time per week and three times by education program designed for increasing attitude of cleansing habit and level of practices, which are the most important and also can be practiced most easily among practice behaviors of skin care by the youth exposed to acne during the period of adolescence. For analysis of the study, frequency analysis and technical statistics were conducted and for level of confidence of the questionnaire, Cronbach`s α and skin care and analysis of factor regarding practice behavior were conducted. In addition, effects of cleansing education program was conducted t-test. changes of cleansing habits used Mc Nemar-test. As the result, cleansing education program provided positive attitudes of changes of cleansing habits and correction of cleansing behavior on skin conditions. Practice behaviors of skin care were divided into skin care habit, skin life habit, and skin sanitation habit factors and skin care habit factor and skin life habit factor showed positive effect with high level of practices(p<0.001). As effects on cleansing habit, it brought changes in rinsing frequency and cleansing substances and it was investigated that rinsing frequency was practiced over five times of rinsing(p<0.001) and the use of form cleanser was increased(p<0.01).

      • KCI등재

        연령과 성별에 따른 비침습적 방법을 이용한 피부측정값의 비교

        박경순 ( Kyoung Soon Park ),오수정 ( Su Jung Oh ),강수경 ( Su Kyung Kang ) 한국미용학회 2009 한국미용학회지 Vol.15 No.2

        This study was to compare the measurements of skin moisture, elasticity and even grain between men and women depending upon their age. Focusing on total 203 residents (male and female; age ranging from 10 to 49) living in Gwangju metropolitan city and Jeonnam province, used ARAMO-TS. It was found that all our subjects hereof scored the following mean points in each skin measurement item: 40.56±4.71 (in moisture), 42.90±11.62 (skin elasticity), and 31.81±7.37 (even grain). Depending upon sex, it was found that women scored higher mean points in the moisture and even grain of skin surface than men (p<0.05). Depending on age, it was found that 10`s group scored highest mean point (42.22±4.33) in the content of moisture among others, and the older age was in significant correlations with the lower moisture content of skin. And it was found that 10`s group scored the highest points in skin elasticity and even grain among others, which was followed by 20`s, 40`s and 30`s group respectively. Here, it is found that 30`s group has worst conditions of skin elasticity and even grain among others (p<0.01). Depending on age and sex, it was found that female group in 10`s and 20`s had significantly better skin elasticity than male group at same age, while female group in 30`s and 40`s had significantly lower skin roughness than male group at same age (p<0.01).

      • KCI등재

        항종양 면역반응 유도를 위한 수지상세포의 최적 활성화 조건

        남병혁,조월순,이기원,오수정,강은영,최유진,도은주,홍숙희,임영진,김기욱,정민호,Nam, Byung-Hyouk,Jo, Wool-Soon,Lee, Ki-Won,Oh, Su-Jung,Kang, Eun-Young,Choi, Yu-Jin,Do, Eun-Ju,Hong, Sook-Hee,Lim, Young-Jin,Kim, Ki-Uk,Jeong, Min-Ho 한국생명과학회 2006 생명과학회지 Vol.16 No.6

        수지상세포는 종양면역에서 필수적인 강력한 CTL 반응을 개시할 수 있는 유일한 세포이다 . 특히 외인성 종양항원에 대한 CTL 반응 유도는 활성화된 수지상세포의 IL-12 분비를 통한 CD4+ helper T세포의 cross-priming을 필요로 한다. 그러나 최근에 활성화된 수지상세포는 $Th_1$ 면역반응을 유도하지만 활성화 시간이 경과함에 따라 오히려 $Th_2$반응을 유도 할 수 있다. 따라서 본 연구에서는 OVA를 종양항원 모델로 설정하여 종양특이적인 CTL 반응을 형성하기 위한 최적의 수지상세포 활성화 조건을 조사하였다. 마우스 골수세포에 서 수지상세포로의 분화는 항원제시 기능을 위한 표면분자의 발현 측면에서 볼 때 배양 6일-7일 정도가 적합하였다. 수지상세포의 IL-12 생성능은 배양 6일 이상, OVA 항원 탑재 8시간 이상의 경우에 연이은 LPS 성숙자극으로 오히려 감소하는 경향을 보였다. 즉 배양 6일의 수지상세포에 OVA 항원 탑재를 8시간 수행한 경우(8-h DC)가 in vitro에서의 IL-12생성능, ex vivo에서의 세포내 $IFN-{\gamma}$를 발현하는 CD8+ T세포의 증가 및 OVA 특이적인 세포독성효과 등에서 가장 좋은 결과를 보였다. 또한 in vivo에서 종양 치료 및 예방효과에서도 8-h DC로 면역한 경우에 가장 우수한 종양형성 억제 효과와 생존기간 연장효과를 보였다. 현재 대부분의 수지상 세포를 이용한 항종양 백신에서 항원 탑재반응을 24시간 동안 수행하고 있으나, 본 실험의 결과로 볼 때, 8시간의 in vitro 항원 탑재가 보다 효과적인 종양특이적 CTL 반응과 항종양 면역반응을 유도함을 알 수 있다. 결론적으로 본 연구를 통하여 8시간 이상의 항원접촉은 수지상세포의 기능적 활성능력을 오히려 고갈시킬 수 있음을 제시한다. Dendritic cells (DCs) are the only antigen presenting cells (APCs) capable of initiating immune responses, which is crucial for priming the specific cytotoxic T lymphocyte (CTL) response and tumor immunity. Upon activation by DCs, CD4+ helper T cells can cross-prime CD8+ CTLs via IL-12. However, recently activated DCs were described to prime in vitro strong T helper cell type 1 $(Th_1)$ responses, whereas at later time points, they preferentially prime $Th_2$ cells. Therfore, we examined in this study the optimum kinetic state of DCs activation impacted on in vivo priming of tumor-specific CTLs by using ovalbumin (OVA) tumor antigen model. Bone-marrow-derived DCs showed an appropriate expression of surface MHC and costimulatory molecules after 6 or 7-day differentiation. The 6-day differentiated DCs pulsed with OVA antigen for 8 h (8-h DC) and followed by restimulation with LPS for 24 h maintained high interleukin (IL)-12 production potential, accompanying the decreased level in their secretion by delayed re-exposure time to LPS. Furthermore, immunization with 8-h DC induced higher intracellular $interferon(IFN)-{\gamma}+/CD8+T$ cells and elicited more powerful cytotoxicity of splenocytes to EG7 cells, a clone of EL4 cells transfected with an OVA cDNA, than immunization with 24-h DC. In the animal study for the evaluation of therapeutic or protective antitumor immunity, immunization with 8-h DC induced an effective antitumor immunity against tumor of EG7 cells and completely protected mice from tumor formation and prolonged survival, respectively. The most commonly used and clinically applied DC-based vaccine is based on in vitro antigen loading for 24 h. However, our data indicated that antigen stimulation over 8 h decreased antitumor immunity with functional exhaustion of DCs, and that the 8-h DC would be an optimum activation state impacted on in vivo priming of tumor-specific CTLs and subsequently lead to induction of strong antitumor immunity.

      • KCI등재

        굼벵이 유래 밀리타리스 동충하초 열수 추출물의 유전독성평가

        조월순(Wol Soon Jo),남병혁(Byung Hyouk Nam),최유진(Yoo Jin Choi),오수정(Su Jung Oh),강은영(Eun-Young Kang),이상호(Sang Ho Lee),정민호(Min Ho Jeong) 한국독성학회 2007 Toxicological Research Vol.23 No.3

        Water extract of Cordyceps militaris grown upon Protuetja dreujtarsis (CMPD) was examined for the genetic toxicity-bacterial mutagenicity, chromosome aberration, and micronucleus formation. For mutagenicity assay, bacterial reversion test with Salmonella typhimurium TA98, TA100, TA1535, TA 1537, and E. coli WP2uvrA were performed. The extract at the concentrations of 50~5,000 ㎍/plate did not induce mutagenicity at all. Chromosome aberration test was performed by using Chinese lung (CHL) cells. There was no significant chromosome aberration in CHL cells with S-9 mixture at the concentrations of 312.5~1,250 ㎍/㎖ of the extract and without S-9 mixture at the concentrations of 1.2~19.5 ㎍/㎖ of the extract. For micronucleus test, ICR mice were treated with the extract at the dose of 0.5, 1, and 2 g/㎏. The frequencies of the micronucleated polychromatic erythrocytes (MNPCE) in bone marrow preparations of the extract-treated group were not increased compared to the untreated control group. Taken together, our results show that water extract of CMPD did not induce any harmful genotoxicity.

      • SCOPUSKCI등재

        굼벵이 유래 밀리타리스 동충하초 열수추출물의 간기능개선 효과 및 단회독성 평가

        조월순(Wol-Soon Jo),남병혁(Byung-Hyouk Nam),오수정(Su-Jung Oh),최유진(Yoo-Jin Choi),강은영(Eun-Young Kang),홍숙희(Sook-Hee Hong),이상호(Sang-Ho Lee),정민호(Min-Ho Jeong) 한국식품과학회 2008 한국식품과학회지 Vol.40 No.1

        굼벵이 유래 밀리타리스 동충하초 열수추출물(CMPD extract)의 안전성 자료를 확보하기 위하여 단회경구투여 독성시험을 실시하였으며, CCl₄의 경구투여로 유도된 간손상 실험동물모델로부터 시험물질(CMPD extract)의 간보호효과를 확인하였다. 단회경구투여 독성시험결과, 시험물질(CMPD extract)의 최고농도(2,000 mg/kg body weight)에서 독성을 나타내지 않아 LD<SUB>50</SUB> 값을 그 이상으로 결정하였다. 또한 독성물질(CCl₄)로부터 간손상이 유발된 SD rat에 시험물질(CMPD extract)을 투여한 후 혈청으로부터 간손상과 관련한 지표물질인 GOT, GPT, TG, TC, LDL 및 HDL 활성도를 측정하였으며, 이와 함께 병리조직학적 소견을 확인하였다. 혈청 GOT는 손상군(G2)에 비해 G4, G5 시험물질투여군에서 유의한 감소를 나타내었으며, GPT의 경우 고용량 시험물질 투여군(G4)에서 유의한 감소를 나타내었다(p < 0.05). 또한 LDL 및 HDL 활성도는 손상군(G2)에 비해 유의하지는 않지만 시험 물질투여군(G4, G5, G6)에서 어느 정도 회복기미를 보였다. 병리조직학적 소견에서도 손상군(G2)의 경우 심각한 세포독성을 보였으나, 시험물질 고용량 투여군(G4)에서는 손상된 세포가 감소하였음을 확인하였다. 이상의 결과들은 굼벵이 유래 밀리타리스 동충하초 열수추출물(CMPD extract)이 CCl₄ 투여에 의해 유발된 급성간 손상에 대하여 간조직의 보호와 간세포의 기능유지에 유효한 물질임을 제시 하고 있다. This study was designed to evaluate the single dose toxicity and the protective effect of water extract of Cordyceps militaris grown upon Protaetia dreujtarsis (CMPD extract) on liver damage on carbon tetrachloride (CCl₄)-induced acute hepatotoxicity in Sprague-Dawley (SD) rats. The CMPD extract was once administered orally to both sexes of rats at dose of 2,000, 1,000 and 500 mg/kg body weight, the recommended maximum limit dose for acute toxicity. Neither significant toxic signs nor death was observed during the observation period. These results indicate that LD<SUB>50</SUB> (lethal dose of 50%) of CMPD extract is greater than 2,000 mg/kg body weight in SD rats. To investigate also the effect of hepatoprotection of CMPD extract, SD rats were orally treated with CMPD extract (50, 25 and 12.5 mg/kg body weight) or silymarin (25 mg/kg body weight) before and after administration of CCl₄ (2 mL/kg body weight, 20% CCl₄ in olive oil). Treatment with CMPD extract or silymarin could decrease the GPT (glutamic-pyruvic transaminase) and GOT (glutamic-oxaloacetic transaminase) levels in serum when compared with CCl₄-treated group. Therefore, the results of this study show that CMPD extract can be proposed to protect the liver against CCl₄-induced hepatic damage in rats.

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