Increased procalcitonin level is a risk factor for prolonged fever in children with Mycoplasma pneumonia

정지은,소지은,곽지희,정혜림,심재원,김덕수,박문수,심정연 대한소아청소년과학회 2018 Clinical and Experimental Pediatrics (CEP) Vol.61 No.8

Purpose: Macrolide-resistant Mycoplasma pneumoniae pneumonia (MPP) is characterized by prolonged fever and radiological progression despite macrolide treatment. Few studies have examined serum procalcitonin (PCT) level in children with MPP. We aimed to investigate the association of acute inflammation markers including PCT with clinical parameters in children with MPP. Methods: A total of 147 children were recruited. The diagnosis of MPP relied on serial measurement of IgM antibody against mycoplasma and/or polymerase chain reaction. We evaluated the relationships between C-reactive protein (CRP), PCT, and lactate dehydrogenase (LDH) levels and white blood cell (WBC) counts, and clinical severity of the disease. We used multivariate logistic regression analysis to estimate the odds ratio for prolonged fever (>3 days after admission) and hospital stay (> 6 days), comparing quintiles 2–5 of the PCT levels with the lowest quintile. Results: The serum PCT and CRP levels were higher in children with fever and hospital stay than in those with fever lasting ≤ 3 days after admission and hospital stay ≤ 6 days. CRP level was higher in segmental/lobar pneumonia than in bronchopneumonia. The LDH level and WBC counts were higher in children with fever lasting for >3 days before compared to those with fever lasting for ≤ 3 days. The highest quintile of PCT levels was associated with a significantly higher risk of prolonged fever and/or hospital stay than the lowest quintile. Conclusion: Serum PCT and CRP levels on admission day were associated with persistent fever and longer hospitalization in children with MPP.

Digital-HF를 이용한 선박 안전 시스템

최성철,소지은 한국항해항만학회 2019 한국항해항만학회 학술대회논문집 Vol.2019 No.춘계

해상 HF대역 디지털 데이터 교환을 위한 통신시스템 분석 및 제안

최성철,소지은,박형철,Choi, Sung-Cheol,So, Ji-Eun,Park, Hyung-Chul 한국정보통신학회 2017 한국정보통신학회논문지 Vol.21 No.12

IMO (International Maritime Organization) has been providing GMDSS (Global Maritime Distress and Safety System) and mandating to install distress and safety systems according to SOLAS. Digital-HF(High-Frequency) coast station communication system maintains interoperability between ship and coast station and digital data exchange in maritime mobile service by digitizing existing analog base voice communication. In this paper, we analyze ITU-R M. 1798-1 established by ITU for digital HF communications and propose Advanced annex2 and new Annex 5 to improve the problems of the existing Annex 2 and Annex 4. The proposed OFDM protocol basically adopts ARQ (Automatic Retransmission Request) which retransmits when an error occurs in a half-duplex manner between an information transmitting side (ISS) and an information receiving side (IRS) and we propose a digital HF communication system and its operational concept which is more reliable and superior than the existing ITU-R M. 1798 by implementing technical development on implementation and performance improvement. 해상통신은 국제해사기구(International Maritime Organization, IMO)에서 세계 해상 조난 및 안전제도(Global Maritime Distress and Safety System, GMDSS)를 마련하고, SOLAS 규약에 따라 조난 및 안전 시스템을 탑재하도록 의무화하고 있다. Digital-HF(High-Frequency) 해안국 통신 시스템은 선박과 해안기지국 사이에 상호 운용성을 유지하며, 기존 아날로그 기반의 음성통신을 디지털화하여 해상이동업무에서 디지털 데이터 교환을 하기 위한 시스템이다. 본 논문은 디지털 HF통신을 위해 ITU에서 제정한 ITU-R M.1798-1을 분석하고, 기존 Annex 2와 Annex4의 문제점을 개선하여 Advanced annex2와 새로운 부속서인 Annex 5를 제안하고자 한다. 제안된 OFDM 프로토콜은 기본적으로 정보 송신측(ISS)과 정보 수신측(IRS)간의 반이중화 방식으로 에러발생시 재전송을 하는 ARQ(Automatic Retransmission Request)방식을 취하고 있으며, 이에 상응하는 구현 및 성능향상에 관한 기술적 개발을 하여 기존에 제시된 ITU-R M.1798-1보다 안정성과 우수성을 확보한 디지털 HF 통신시스템을 제안하고자 한다.

유명 연예인 자살보도가 일반인의 자살시도에 미치는 영향

신미영,소지은,김진숙,박미미,박지원,Shin, Mi-Young,So, Ji-Eun,Kim, Jin-Sook,Park, Mi-Mi,Park, Jee-Won 한국가정간호학회 2010 가정간호학회지 Vol.17 No.2

Purpose: The study explored the influence of the suicide of two famous entertainers on the suicide attempts of the public. Method: The subjects of the descriptive study were 888 suicide attempt patients recruited from October 2007 to September 2009 in an emergency centre located in S-city. The research tools were developed at the Centre for Disease Control. Results: The frequency of suicide attempts during the 6 months and 12 months preceding and following the gas-related suicide of celebrity A were ${\chi}^2$=18.14 and ${\chi}^2$=25.97, respectively, and both were significant(both p<.001). The frequency of suicide attempts of the 6 and 12months before and after the release of report of celebrity B's hanging suicide were ${\chi}^2$=3.85 and ${\chi}^2$=3.47, respectively, and both were significant (both p<.05). Conclusion: These results showed that reports of suicide of celebrities influences suicide attempts of the public. Multiple factors that can influence suicide attempts should be further identified and researched.

소아 비염 환자에서 혈청 비타민 D 및 interleukin-31 수치와 알레르기비염 및 비알레르기비염과의 관계

박성준,소지은,박문수,정혜림,심재원,김덕수,심정연 대한 소아알레르기 호흡기학회 2018 Allergy Asthma & Respiratory Disease Vol.6 No.1

Purpose: Serum vitamin D (25-hydroxyvitamin D, 25[OH] D) and interleukin-31 (IL-31) are related to atopic dermatitis, but their relationship with allergic rhinitis is unclear. The purpose of this study was to compare the levels of serum IL-31 and 25 (OH) D between the allergic rhinitis (AR), nonallergic rhinitis (NAR), and control groups and to investigate the relationship between IL-31 and 25 (OH) D. Methods: We recruited 59 children with only rhinitis and 33 controls without any allergic diseases. Serum IL-31 and 25(OH) D levels were assayed using an enzyme-linked immunosorbent assay and high-performance liquid chromatography, respectively. The patients were considered to have atopic sensitization if the levels of serum specific IgE to inhalant allergens as assessed using immunoCAP were ≥0.35 IU/mL or if they tested positive for one or more allergens by the skin prick test. Results: Of children with rhinitis, 25 had nonatopy (NAR), and 34 children had atopy (AR). Serum 25(OH) D levels were significantly lower in the rhinitis group than in the control group, while there was no significant difference serum 25(OH) D levels between the AR and NAR groups. Children with rhinitis demonstrated higher serum IL-31 levels than controls; however, there was no difference in serum IL-31 levels between the AR and NAR groups. Serum 25(OH) D levels were inversely correlated with serum IL-31 levels and blood eosinophil counts. On the other hand, serum 25(OH) D levels were not correlated with total serum IgE levels. Conclusion: Serum 25(OH) D and IL-31 may play a role in the pathogenesis of rhinitis via mechanisms other than IgE-related pathway.

특실 입원환자의 만족도 향상

한진이,임오례,공민송,소지은 한국의료QA학회 2008 가을학술대회 Vol.2008 No.3

일개 대학병원의 간호관리료 등급변화에 따른 간호사의 간호활동시간 비교

박정옥,김혜용,노경식,노영덕,박명분,소지은,박미미,방경숙 병원간호사회 2010 임상간호연구 Vol.16 No.1

Purpose: The purpose of this study was to examine the difference between direct and indirect nursing activity times according to the grade of nursing management fee. Methods: The subjects of this study were 324 working nurses at the time of 3rd grade and 319 working nurses at the 2nd grade of nursing management fee in one university hospital. Nursing activity time was measured in April and May, and in September and October of 2008 for comparison. The data were analyzed by SPSS win using frequency and t-test. Results: Direct nursing care activity time per one patient was significantly higher at 2nd grade than 3rd grade in day shift (t=-2.55, p=.012). Direct nursing care workload per one nurse was significantly lower at 2nd grade than 3rd grade in evening shift (t=2.21, /?=.030), whereas indirect nursing care workload was lower at 2nd level in night shift (t=2.43 p=.016). Conclusion: The findings from this study showed that higher nurse-to-patient ratio can provide greater amount of direct nursing care activity for the patient. Also, it decreased workload of nurses. The higher nurse-to-patient ratio will be beneficial for promoting quality of nursing care as well as decreasing nurse's heavy workload.