시_박철

박철 새얼문화재단 2007 황해문화 Vol.57 No.-

개의 Ethylene Glycol 중독에 대한 에탄올의 경구투여 효과

박철만,한홍률,Part Cheol-Man,Han Hong-Ryul 한국임상수의학회 1987 한국임상수의학회지 Vol.4 No.1

The present studies were undertaken in attempt to investigate the therapeutic effect of ethanol in dogs intoxicated with ethylene glycol Three dogs treated with ethylene glycol and other three dogs with ethylene glycol plus 20% ethanol orally were examined on clinical signs, endoscopic views, histopathological findings, and autopsy findings respectively. The results obtained were summarized as fellows : 1. The clinical sings and their severity of dogs intoxicated with ethylene glycol were time related and progressed from vomiting, depression, thirsty, tachycardia, tachypnea, convulsiot ataxia, melena, uremia and coma, but clinical signs of dogs treated with ethylene glycol and ethanol simultaneously only stowed vomiting and thirsty. 2. In the gastroscopic view, the dogs intoxicated with ethyelne glycol showed edematous, hyperemia, errosive and ulcerative lesions in the fundus and body area but the dogs treated with ethylene glycol and ethanol simultanously showed edematous and hyperemic lesions. 3. Oral treatment of ethanol with ethylene glycol simultaneously have reduced the signs of EG intoxications in dogs.

Association between Childhood Trauma and Suicidal Behavior in the General Population

박철,박인후,유태영,김하늬,유승형,이주연,김재민,김성완 전남대학교 의과학연구소 2021 전남의대학술지 Vol.57 No.2

This study aimed to investigate the associations between various types of childhood trauma and suicidal behavior in the general population in South Korea. This mental health survey included a total of 1,490 general citizens living in a metropolitan South Korean city who completed a questionnaire that assessed respondents’ histories of childhood trauma before the age of 12 years, including bullying victimization, emotional abuse, sexual abuse, and physical abuse, as well as suicidal behavior, including current suicidal ideation and histories of suicide planning and attempts. The following psychiatric scales were administered: Hospital Anxiety and Depression Scale (HADS), Rosenberg Self-Esteem Scale (R-SES), Connor-Davidson Resilience Scale (CD-RISC), Perceived Stress Scale (PSS), and visual analogue scale of EuroQol 5D (EQ-5D). Participants who experienced any childhood trauma had significantly higher HADS and PSS scores, and significantly lower EQ-5D scores. Additionally, participants with any type of childhood trauma were significantly more likely to have current suicidal ideation and histories of planned and attempted suicide. Multivariate analyses adjusted for confounding variables indicated that bullying victimization and sexual abuse were associated significantly with all types of suicidal behavior. Physical abuse was associated significantly with histories of suicide planning and attempts. The present findings showed that any type of childhood trauma was associated with higher levels of suicidality, anxiety, depression, and perceived stress, as well as lower health-related quality of life, in the general population. In particular, associations between childhood trauma and suicidality were identified after adjustment for confounding variables.

지역정당 대체역할로서의 주민자치주체기구의 중요성

박철 한국자치학회 2017 월간 주민자치 Vol.69 No.-

사용자 중심의 SLA 지표 선정 방법론

박철한 ( Chul-han Park ),김상수 ( Sangsoo Kim ),인호 ( Hoh In ) 한국정보처리학회 2006 한국정보처리학회 학술대회논문집 Vol.13 No.2

IT 서비스의 안정적인 공급과 IT 서비스 품질 개선을 이루고자 하는 SLA (Service Level Agreement)에 대해 많은 연구와 시도가 지금까지 진행되어 왔다. SLA 시행에 있어서 측정 지표와 그 평가 기준 선정은 매우 중요하나, 대부분 SLA 측정 지표들은 기술관점의 항목들로 구성되어 있기 때문에, SLA 시행 결과가 사용자 중심이 아닌 서비스 제공자 중심으로 나타나고 있다. 이는 사용자의 불만족을 초래하고 서비스 제공자와의 의사 소통을 어렵게 만들고, 결국 SLA 도입 실패로 이어지는 원인이 되고 있다. 본 연구에서는 기존의 SLA 측정 지표들에서, 사용자 중심의 SLA 측정 지표로 활용할 수 있는 항목들을 BSC 의 인과관계모델을 통해 추출하고, AHP 기법을 통해 SLA 평가 기준들과 측정 지표들에 대한 가중치를 도출하였다. 이를 통하여 사용자 관점의 SLA 지표 선정 방법에 대한 명확한 기준을 제시하였다.

연명치료 중단의 허용기준

박철 민사판례연구회 2010 民事判例硏究 Vol.- No.32

A 76-aged woman suffered serious brain damage caused by hypoxia during pulmonary tumors biopsy in a general hospital. She didn't recover consciousness for several months in PVS. Her family requested the hospital for the withholding of life-sustaining treatment, but the hospital refused. They filed a civil action against the hospital for the removal of artificial respiration system. 2009. 5. 21. the Supreme Court of Korea decided for the plaintiffs. It was the first case in Korea for the withholding of life-sustaining treatment for a PVS patient. By Court's opinion, the withholding of life-sustaining treatment for a PVS patient is lawful only when the case meets the following requirements. First, the patient is in a reversible step to death. The reversible step to death must be decided only when her or his unconsciousness is unrecoverabl, she or he is incurable and hopeless, and she or he is expected to die in short term. Second, the patient indicated the advance directives for the withholding of life-sustaining treatment. Otherwise, at least, the patient's will would be presumed through her or his words, writings, character, religious faith, responses to other PVS cases, ages, side effects and sufferings caused by the treatment. The Court's decision removed the unstableness of law about the withholding of life-sustaining treatment for a PVS patient. But I think that the requirement of the expectation of death in short term in the Court's opinion is too rigid.

Tracheobronchial Foreign Body in a Shih-tzu Dog; Diagnostic and Therapeutic Trial Using Bronchoscopy

박철,유종현,박희명 한국임상수의학회 2009 한국임상수의학회지 Vol.26 No.4

A 4-year-old, neutered male Shih-tzu dog weighing 5.4 kg was referred due to anorexia and chronic coughing. Based on history, physical examination, laboratory tests, radiographic findings, echocardiography, and bronchoscopic examination, the dog was diagnosed as tracheobronchial foreign body. The foreign body was steamed rice debris, which was removed by bronchoalveolar lavage (BAL) with vacuum suction of bronchoscopy. Bacterial and fungal culture of collected BAL fluid was negative. Baermann test for lungs parasites also was negative. The dog was treated with bronchodilator, antibiotics, anti-inflammatory agent, and mucolytics for 7 days. Appetite increased and coughing sign was clearly improved after removal of foreign body and medical therapy. This case report describes that bronchoscopic techniques are available for the evaluation and management of airway foreign bodies.

Comparison of Metabolic Risk Factors in Urolithiasis Patients according to Family History

박철,하윤석,김용준,윤석중,이상철,김원재 대한비뇨의학회 2010 Investigative and Clinical Urology Vol.51 No.1

Purpose: Urolithiasis develops more frequently in patients with a family history (FHx). However, little is known about risk factors in stone formers with a FHx. The aim of this study was to examine the clinico-metabolic characteristics of urinary stone formers according to FHx. Materials and Methods: A database of 1,068 stone formers who underwent a complete metabolic evaluation was reviewed. The patients were divided into two groups on the basis of the presence of a FHx. Clinical factors and metabolic parameters were compared between the two groups. Results: There were no significant differences in clinical characteristics, such as gender, age, body mass index, stone episodes, or multiple stones, between the two groups (p>0.05, respectively). Compared with stone formers without a FHx, however, serum calcium concentrations were more elevated in stone formers with a FHx. Also, the urinary excretion of calcium was higher in stone formers with a FHx than in those without a FHx. Other urinary metabolites showed no significant differences between the two groups (p>0.05, respectively). Conclusions: Our study revealed that stone formers with a FHx had increased urinary calcium excretion as well as elevated concentrations of serum calcium. This finding suggests that urolithiasis in stone formers with a FHx may be associated with calcium metabolic abnormalities. Purpose: Urolithiasis develops more frequently in patients with a family history (FHx). However, little is known about risk factors in stone formers with a FHx. The aim of this study was to examine the clinico-metabolic characteristics of urinary stone formers according to FHx. Materials and Methods: A database of 1,068 stone formers who underwent a complete metabolic evaluation was reviewed. The patients were divided into two groups on the basis of the presence of a FHx. Clinical factors and metabolic parameters were compared between the two groups. Results: There were no significant differences in clinical characteristics, such as gender, age, body mass index, stone episodes, or multiple stones, between the two groups (p>0.05, respectively). Compared with stone formers without a FHx, however, serum calcium concentrations were more elevated in stone formers with a FHx. Also, the urinary excretion of calcium was higher in stone formers with a FHx than in those without a FHx. Other urinary metabolites showed no significant differences between the two groups (p>0.05, respectively). Conclusions: Our study revealed that stone formers with a FHx had increased urinary calcium excretion as well as elevated concentrations of serum calcium. This finding suggests that urolithiasis in stone formers with a FHx may be associated with calcium metabolic abnormalities.

Spontaneously Occurring Chemodectoma in a Yorkshire Terrier Dog

박철,유종현,김대영,박희명 한국임상수의학회 2008 한국임상수의학회지 Vol.25 No.3

A 7-year-old, intact female Yorkshire terrier dog was presented for coughing, anorexia, chest pain and dyspnea. Right lateral thoracic radiograph demonstrated a large mass shape on the heart base with decreased cardiac silhouette and severe right deviation of the trachea with the heart shifted to the left thoracic wall was observed on the ventrodorsal thoracic projection. Echocardiographic examination revealed a large rounded mass compressing left atrium around the heart base without signs of pericardial effusion. On computed tomographic (CT) findings, sagittal CT images depicted the possibility of cranial vena caval invasion and heart base involvement of the mass associated with biatrial compression. Dorsal CT image revealed the right deviation of trachea due to the heart base mass and markedly shrunk lung space was detected on the transverse CT image. Because the dog suddenly had died during the recovery from anesthesia after finishing CT scan, necropsy was performed. On gross findings, a large and lobulated mass was located at the base of the heart. A poorly-demarcated, infiltrative, multilobulated tumor composed of polyhedral cells in solid cellular sheets was confirmed based on histopathologic examination. This dog was diagnosed as a chemodectoma. This case report describes the clinical findings, diagnostic consistency of thoracic radiography, echocardiography and CT, and histopathologic confirmation in a spontaneously occurring chemodectoma with a Yorkshire terrier dog.

Induction of Apoptosis by Curcumin in Human Leukemic U937 Cells Through Activation of Caspases and Upregulation of Fas/FasL Expression

박철,이원호,최병태,최영현 한국유전학회 2007 Genes & Genomics Vol.29 No.2

meric, the dried rhizome of Curcuma longa L, has emerged as one of the most powerful chemopreventive and anticancer agent. Its biological efects range from anti-oxidant and anti-inflamatory to inhibition of angiogenesis and is also shown to possess specific antitumoral activity. In this stu d y , w e i n v e s t i g a t e d t h e e f e c t s o f s showed that curcumin inhibits the growth of U937 cels by inducing apoptosis, as evidenced by the formation of apoptotic bodies, DNA fragmentation and the acumulation of the sub-G1 phase. Western blot analyses showed that treating the cells with curcumin did not afect the levels of Bcl-2 family members such as Bax, Bad, Bcl-2 and ch as c-IAP1 and c-IAP2 were slightly down-regulated in a concentration-dependent manner. The apoptosis of U937 cels by curcumin was found to be associated with an elevated Fas and FasL proteins expression. Furthermore, a marked proteolytic activation of caspase-3 and caspase-8, and degradation/cleavage of poly (ADP- ribose) lts indicate that the Fas/FasL pathway might be involved in curcumin-induced apoptosis of U937 cels.