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김효린,유화승,백동기,박인해,장철용,김효영,하예진,문구,Kim, Hyo-rin,Yoo, Hwa-seung,Baek, Dong-gi,Park, In-hae,Jang, Chul-yong,Kim, Hyo-young,Ha, Ye-jin,Moon, Goo 대한한방내과학회 2016 大韓韓方內科學會誌 Vol.37 No.1
Objectives: The purpose of this study was to present the clinical guidelines and traditional Korean medicines for gastric cancer.Results: Gastric cancer is the second most common cancer in Korea. Recent studies have reported that applying integrative Oriental and Western medicine can suppress the tumor, improve the survival, the immune system, and the quality of life in gastric cancer. However, there still is no unified protocol for gastric cancer treatment, which produces difficulty in clinical applications. In Korea, a “Synopsis on the Clinical Practice Guidelines of Gastric Cancer” was published by the Korean Journal of Gastroenterology in 2014. In China, Oriental medicine clinical practice guidelines were published for the first time in 2014. The present author proposed “Clinical Practice Guidelines of Korean Medicine for Gastric Cancer” in 2014, but there is a need for more advanced guidelines with reference to the aforementioned Oriental and Western guidelines. This study will be helpful for understanding and building systems for integrative gastric cancer treatment.Conclusions: Further studies on integrative gastric cancer treatment are needed to improve the survival of gastric cancer patients and build the clinical practice guidelines for gastric cancer.
김효린,정혜련,백동기,원진희,문구,Kim, Hyo-Rin,Jeong, Hye-Ryon,Baek, Dong-Gi,Won, Jin-Hee,Moon, Goo 대한암한의학회 2014 大韓癌韓醫學會誌 Vol.19 No.1
Objectives : The purpose of this study was to present the clinical guidelines for gastric cancer. Methods : The literature on Western and Oriental medical treatment of gastric cancer were collected, analyzed and summarized from the Google Scholar, KIOM OASIS and PUBMED from 1993 to 2014. Results : Gastric cancer is the second most common cancer in Korea. In recent studies, applying integrative oriental and western medicine can suppress the tumor, improve the survival, the immune system, and the quality of life in gastric cancer. But there isn't still a unified protocol for gastric cancer treatment, so we have difficulty in clinical application. This study will be helpful for understanding and building systems for integrative gastric cancer treatment. Conclusion : Further studies on integrative gastric cancer treatment are needed to improve the survival of gastric cancer patients and build the clinical practice guidelines of gastric cancer.
간세포암의 부분 간절제술 후 한방치료로 복수를 동반한 간경변 증상이 호전된 환자 증례보고
김효린,정혜련,장철용,우찬,하예진,문구,백동기,Kim, Hyo-rin,Jeong, Hye-ryon,Jang, Chul-yong,Woo, Chan,Ha, Ye-jin,Moon, Goo,Baek, Dong-gi 대한한방내과학회 2015 大韓韓方內科學會誌 Vol.36 No.3
Objectives The purpose of this study is to report the possibility of treatment of liver cirrhosis with traditional Korean medical treatment. Methods A 57-year-old man diagnosed with hepatocellular carcinoma and liver cirrhosis was admitted to Wonkwang University Oriental Medical Hospital in August 2014. He underwent liver lobectomy and later experienced abdominal pain, anorexia, and insomnia. To control cirrhotic ascites and prevent relapses, he opted to receive HangAmDan-B (HAD-B) and cultivated wild ginseng herbal acupuncture therapy. Results After treatment, the volume of ascites decreased and the patient&’s symptoms such as abdominal pain and anorexia improved. Conclusions This report suggests that HAD-B and cultivated wild ginseng herbal acupuncture therapy may play a therapeutic role in liver cirrhosis occurring after liver lobectomy.
뇌졸중 환자에게 유치도뇨관 삽입 이후 발생한 다제내성 녹농균 요로감염 한방치험 1례
장철용,김효린,황규상,유근정,이수영,김준현,김민수,신용진,신선호,Jang, Chul-yong,Kim, Hyo-rin,Hwang, Gyu-sang,Yu, Keun-jeong,Lee, Su-yeong,Kim, June-hyun,Kim, Min-soo,Shin, Yong-jeen,Shin, Sun-ho 대한한방내과학회 2016 大韓韓方內科學會誌 Vol.37 No.6
This case study reports on the effect of Korean medicine on a catheter-associated urinary tract infection (CAUTI) caused by multidrug-resistant Pseudomonas aeruginosa. An 83-year-old man diagnosed with stroke had dysuria, and it was found that an indwelling urinary catheter led to CAUTI. From laboratory tests, we identified multidrug-resistant Pseudomonas aeruginosa and applied Korean medicine to him. After herbal medication with acupuncture and moxibustion, we studied a urinalysis and urine culture again for follow-up. We found meaningful improvement in bacteriuria and bacterial identification. This case suggests that Korean medicine could have a beneficial effect on urinary tract infections caused by multidrug-resistant Pseudomonas aeruginosa.
지실과 자초 전탕액 외치법을 병행한 간경변 환자의 노인성 가려움증 치험 1례
박인해,문구,김효린,김준현,홍석훈,Park, In-Hae,Moon, Goo,Kim, Hyo-Rin,Kim, June-Hyun,Hong, Seok-Hoon 대한한방안이비인후피부과학회 2016 한방안이비인후피부과학회지 Vol.29 No.3
Objectives : Pruritus is a skin disorder that usually occurs in the elderly. The purpose of this study is to report the effect of external preparation containing Ponciri fructus and Radix lithospermi on senile pruritus and xeroderma with liver cirrhosis.Methods : We treated 85-years-old liver cirrhosis patient suffered from itching sensation on the whole body with external preparation containing Ponciri fructus and Radix lithospermi and oral administration of Sodalgeonbitang for 37 days.Results : Despite discontinuing western medical treatment of topical steroids and oral antihistamine, pruritus and erythema of the patient were significantly improved.Conclusions : As for external application, decoction of Ponciri fructus and Radix lithospermi might be effective used for treatment senile pruritus and xeroderma.
십자절개침법을 이용한 멜라닌 세포성 모반 치료의 치험 1례
김혜윤,박인해,홍석훈,신선호,김효린,박승구,Kim, Hye-Yoon,Park, In-Hae,Hong, Seok Hoon,Shin, Sun-Ho,Kim, Hyo-Rin,Park, Sung-Gu 대한한방안이비인후피부과학회 2016 한방안이비인후피부과학회지 Vol.29 No.2
Objectives : The objective of this study was to report the efficacy of the Crucial Incision Acupuncture Therapy(CIAT) for removing melanocytic nevi. Methods : CIAT is penetration acupuncture to remove a lesion by sticking needles like cross-shape. We used the CIAT for treating one patient with melanocytic nevi, and then we investigated efficacy and side effect for about 5 months. Results : In 16 melanocytic nevuses treated with CIAT, one of the nevuses recurred after about 3 months. And hyperpigmentation lasted for about 2-5 months was caused after the CIAT. Conclusions : In Korean medicine, the CIAT might be used for treating melanocytic nevi. But additional studies might be needed for improvement of treatment effect.
사람 신경모세포종 SH-SY5Y 세포주의 파킨슨 모델에 대한 소속명탕(小續命湯)의 보호효과
우찬,유주연,장철용,김효린,신용진,문아지,신선호,Woo, Chan,You, Ju-Yeon,Jang, Chul-Yong,Kim, Hyo-Rin,Shin, Yong-Jeen,Moon, A-Ji,Shin, Sun-Ho 대한한방내과학회 2014 大韓韓方內科學會誌 Vol.35 No.3
Objectives: In this study we made an effort to investigate the protective effect of SSMT on the N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) -induced cytotoxicity of SH-SY5Y cells. Methods: The cell viability was assessed by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MMT) assay. The fluorescence intensity was measured by using a dye and then with propidium iodide (PI) DNA flow cytometry analysis of the effects on the cell cycle of the SH-SY5Y cells and were used to measure the fluorescence of intracellular reactive oxygen species generation by MPTP. Results: Pretreatment of SSMT significantly suppressed MPTP-induced cytotoxicity, which was revealed as apoptosis characterized by the reduction of cell viability, the increase of ROS production, and the loss of mitochondrial membrane potential in SH-SY5Y cells. Conclusions: These findings suggest that SSMT exerts neuroprotective effects on human neuroblastoma SH-SY5Y cells by MPTP-induced dopaminergic neurodegeneration.