골프 클럽 별 볼 위치 선정 시 재고해야 할 이슈: 바운스 각의 중요성에 대한 이론적 고찰

강상범(Kang, Sang Bum),양명환(Yang, Myung-Hwan) 한국코칭능력개발원 2023 코칭능력개발지 Vol.25 No.3

입원한 남성과 여성 알코올 의존 환자간의 임상적 특징 및 기질 성격 특성의 차이

이상백(Sang Baek Lee),이정식(Jung Sik Lee),송진우(Jin Woo Song),강상범(Sang Bum Kang),김응조(Eung Jo Kim),홍계현(Kye Hyun Hong),조성민(Sung Min Cho),이석진(Suk-Jin Lee),장순우(Soon Woo Chang) 한국중독정신의학회 2010 중독정신의학 Vol.14 No.1

Objective:Although researchers have performed many stu-dies attempting to understand alcoholics’ characteristics, few have conducted direct comparative studies between male and female alcoholics. This study examined the differences in Temperament and Character Inventory (TCI) scores and in clinical characteristics between male and female alcoholics, to discern new treatment possibilities for both groups. Method:Study participants were 55 male and 49 female patients with alcohol dependence. We obtained their demographic data and TCI scores. Additionally, we identified each group’s clinical characteristics from information on their drinking habits and suicidality histories and from the results of administering the Buss-Durkee Hostility Inventory (BDHI), the Acute Physiological and Psychological Response after Drinking, and the Michigan Alcohol Screening Test (MAST-K) to them. Results:Female patients had higher scores on Harm-Avoidance (HA) and lower scores on Reward-Dependence (RD) and Cooperative (CO) as compared to male patients. Male alcoholics had earlier ages of drinking onset and higher scores on Anger Control. Female alcoholics tended to have more suicidal thoughts and attempts. In the presence of a positive familial history, female alcoholics had higher scores on Spontaneous Aggression and lower scores on Novelty-Seeking (NS) and Reward-Dependence (RD) than did male alcoholics. Conclusion:These results suggest that male alcoholics tend to have more biological traits than female patients have and that female patients have more Editor’s note re highlight: Please clarify. Some information seems to be missing here. psychological problems than male patients have. These differences between male and female alcoholics should be incorporated into treatment processes for patients with alcohol dependence.

여성 알코올 의존 입원환자의 음주 양상 및 기질 성격 특성

이상백(Sang-Baek Lee),이정식(Jung-Sik Lee),송진우(Jin-Woo Song),강상범(Sang-Bum Kang),김응조(Eung-Jo Kim),홍계현(Kye-Hyun Hong),조성민(Sung-Min Cho),이석진(Suk-Jin Lee),장순우(Soon-Woo Chang) 한국중독정신의학회 2009 중독정신의학 Vol.13 No.1

Objective:This study examined the temperament and character inventory (TCI) scores as well as demographic and clinical data of female alcoholic patients, in order to discern new treatment possibilities for them. Methods:Forty-three female patients with alcohol dependence and thirty-two female social drinkers were included in this study. Female patients were divided into subgroups with positive and negative family histories. The presence or absence of drinking problems in the hus-band was also recorded. The demographic data and the TCI scores of groups were obtained. The clinical characteristics of each group were identified by obtaining information about drinking habits and childhood victimization histories, and by administer-ing the Beck Depression Inventory (K-BDI), State-trait Anxiety Inventory (STAI), Buss-Durkee Hostility Inventory (BDHI), Acute Physiological and Psychological Response after Drinking, and the Michigan Alcohol Screening Test (MAST-K). Results:Higher scores of Self-Transcendence (ST) and lower scores of Self-Directedness (SD) were shown in female patients compared to normal controls. Female alcoholics had higher scores on the BDI and STAI, and tended to have more suicidal thoughts and attempts. They also showed higher rates of childhood victimization experiences such as physical abuse. Conclusion:TCI profiles of the female alcoholic patients compared with normal healthy subjects reflected common comorbid psychiatric conditions such as depression, anxiety disorder, and personality dis-order. The evaluation of childhood traumatic experience and suicidal risk should be included in the treatment process for fe-male alcoholics.

위샘종과 위샘암종에서의 세포자멸사와 세포증식

이동수,강상범,이승우,남순우,유영경,한석원,Lee, Dong-Soo,Kang, Sang-Bum,Lee, Seung-Woo,Nam, Soon-Woo,Yoo, Young-Kyung,Han, Sok-Won 대한위암학회 2006 대한위암학회지 Vol.6 No.2

목적: 일반적으로 DNA가 손상된 세포들은 사멸되거나 적절히 손상된 부위를 복구하여 항상성을 유지하거나, 손상된 DNA를 가지고 계속 증식하여 결국 암으로 진행한다. 그러므로 세포자멸사와 세포증식의 균형의 변화는 조직 항상성 및 암 발생의 중요한 조절기전이다. 이에 본 연구자들은 위샘종 또는 위샘암종 조직을 대상으로 세포 사멸 및 세포증식의 정도를 보고자 하였다. 대상 및 방법: 내시경적으로 절제된 위샘종 41예, 외과 수술로 절제된 위샘암종 100예를 대상으로 면역조직화학적 검사를 시행하여 Ki-67 labelling 지수를 구하고, TUNEL 방법을 이용하여 세포자멸사 지수를 구하여 위샘종에서의 이형성 정도에 따른 발현도의 차이 및 위샘암종에서의 조직분류 및 병기에 따른 발현도의 차이를 관찰하였다. 결과: Ki-67 labelling 지수는 위샘종 $51.90{\pm}1.45$, 위샘암종 $55.33{\pm}0.94$로서 위샘암종에서 의의 있게 높았다(P<0.05). 세포자멸사 지수는 위샘종 $53.27{\pm}2.67$, 위샘암종 $42.41{\pm}1.32$로서 위샘종에서 의의 있게 높았다(P<0.05). 위샘종에서 이형성에 따른 Ki-67 labelling 지수 및 세포자멸사 지수는 차이가 없었다. 위샘암종에서 Ki-67 labelling 지수 및 세포자멸사 지수는 Lauren 분류법에 의한 장형과 미만형, 조기 위암과 진행성 위암, 림프절 전이 유무, TNM 분류에 따른 각 군 간의 통계학적 차이는 보이지 않았다. 결론: 샘암종에서의 세포자멸사 지수와 Ki-67 labelling 지수에 대한 연구에서 위샘종은 위샘암종보다 좀 더 정적인 결과를 보이고, 위암발생에서는 세포증식이 중요한 역할을 하나 이 두 지수가 위암의 조직학적 분류 및 병기에 따른 예후와는 관련이 없었다. Purpose: Cancer is a genetic disease caused by alterations in key regulators of cell growth and cell turnover, We investigated apoptotic cell death and cell proliferation in gastric adenomas and adenocarcinomas. Materials and Methods: The TdT-mediated dUTP-biotin nick end labelling (TUNEL) method and immunohistochemistry for Ki-67 were peformed, using paraffin-embedded tissues of 41 gastric adenomas and 100 gastric adenocarcinomas. These results were compared with histopathologic parameters. Results: The Ki-67 labelling index was higher in adenocarcinomas than in adenomas and the apoptotic index was higher in adenomas than in adenocarcinomas. There were no significant difference between the apoptotic index/Ki-67 labelling index and clinicopathological parameters. Conclusion: We propose that cell proliferation is more closely associated with gastric adenocarcinomas than apoptosis is, but that neither has any clinical significance as a prognostic factor in gastric adenocarcinomas. (J Korean Gastric Cancer Assoc 2006;6:91-96)

교대근무자에서 야간 광 노출에 따른 수면양상 및 기분상태 변화

권기범,윤인영,강상범,정도언,Kwon, Ki-Bum,Yoon, In-Young,Kang, Sang-Bum,Jeong, Do-Un 대한수면의학회 1999 수면·정신생리 Vol.6 No.1

목 적 : 본 연구는 야간 광 노출시 야간교대근무자의 수면양상과 기분상태가 어떠한 변화를 보이는지와 광 노출의 부작용의 정도와 빈도를 알아보고자 하였다. 이런 과정을 통해 광 노출이 야간교대근무적응에 사용될 수 있는지를 밝히고자 하였다. 방 법 : 용인정신병원에 근무하는 야간교대근무 간호사 12명이 본 연구에 참여하였다. 본 연구는 야간근무 대조연구, 야간근무 광노출연구, 주간근무 대조연구의 3부분으로 구성 되었으며 1명의 간호사가 주간근무 대조연구에 참여하지 않은 것을 제외하고는 모든 간호사가 세 연구에 모두 참여하였다. 야간근무 광노출연구시 새벽 1시부터 새벽 5시까지 4시간동안 빛에 노출되었다. 수면양상은 활동기록기와 자동수면 분석프로그램을 통해, 기분상태와 광노출의 부작용은 자기보고척도에 의해 평가하였다. 결 과 : 수면기간시간, 총수면시간, 수면효율은 야간근무 대조연구에 비해 야간근무 광노출연구시 증가되었으며 야간근무 광노출연구는 주간근무 대조연구와 차이를 보이지 않았다. 야간근무 광노출연구시 수면효율의 일간변동도 야간근무 대조연구에 비해 현저하지 않고 안정된 양상을 보였다. 야간근무 광노출연구시 간호사들은 주간수면을 취한 후 저녁시간에 야간근무 대조연구에 비해 좀 더 기분이 고양되고 활기가 넘친다고 보고하였다. 광 노출이 진행되면서 광노출 부작용에 대한 내성이 생겨 부작용의 빈도나 정도가 감소하였으며 광노출 3일째 심한 정도의 부작용을 호소한 사람은 한명도 없었다. 결 론 : 광 노출시 주간수면은 주간근무시의 야간수면만큼 호전되는 것으로 관찰되었고 이러한 수면호전으로 인해 야간교대근무자들은 기분이 고양되고 좀 더 활기가 넘친다고 보고하였다. 광 노출의 부작용도 시간이 지남에 따라 감소하므로 야간교대근무 적응을 위해 광 노출법을 권장할 수 있을 것이다. Objectives: We intended to observe changes in sleep patterns and mood states of night-shift workers following light exposure. We also estimated the degree of tolerance of light exposure. By studying these, we investigated the possibility of applying light therapy to night-shift workers for improving their adaptation. Methods: Twelve night-shift nurses working at Yong-In Mental Hospital volunteered to participate in this study. The study consisted of 3 parts: 1) night-shift control study; 2) light exposure study; 3) day-shift control study. All the nurses accomplished 3 parts of the study, each of which continued for 3 days, except one nurse who did not participate in day-shift control study. During light exposure study, nurses were exposed to bright light for 4 hours from 1AM to 5AM. Sleep patterns were evaluated with wrist actigraphy and automatic sleep analysis program. Mood states and side effects of light exposure were assessed with self-report scales. Results: Sleep period time, total sleep time, and sleep efficiency were increased following light exposure compared with night-shift control study. Light exposure study showed no difference from day-shift control study in above-mentioned sleep parameters. Daily fluctuation of sleep efficiency was less prominent during light exposure study than during night-shift control study. During light exposure study, the subjects felt more elated and energetic in the evening after daytime sleep than during night-shift control study. None of the subjects complained of severe side effects related to light exposure on the third day of light exposure. Tolerance of side effects was noted to develop with the repetition of light exposure. Conclusion: Light exposure improved the daytime sleep of night-shift workers to the level of normal nighttime sleep, making the subjects more elated and energetic. Side effects of light exposure were found to be tolerable. Light exposure seems to be safely applicable to night-shift workers for their adaptation.

6개월 이상 지속되는 복통으로 내원한 18세 남자

이신희 ( Shine Hee Lee ),강상범 ( Sang-bum Kang ) 대한내과학회 2022 대한내과학회지 Vol.97 No.6

염증성 장질환 환자의 간담도계 발현

서광일 ( Kwang Il Seo ),강상범 ( Sang-bum Kang ) 대한소화기학회 2019 대한소화기학회지 Vol.73 No.5

The hepatobiliary system is one of the most common sites of extraintestinal manifestation in patients with inflammatory bowel disease (IBD). The progression of IBD can lead to a primary hepatobiliary manifestation and can occur secondary to multiple drugs or accompanying viral infections. Primary sclerosing cholangitis is the representative hepatobiliary manifestation of IBD, particularly in ulcerative colitis. Although most agents used in the treatment of IBD are potentially hepatotoxic, the risk of serious hepatitis or liver failure is low. The prevalence of HBV and HCV in IBD is similar to the general population, but the clinical concern is HBV reactivation associated with immunosuppressive therapy. Patients undergoing cytotoxic chemotherapy or immunosuppressive therapy with a moderate to high risk of HBV reactivation require prophylactic antiviral therapy. On the other hand, HCV has little risk of reactivation. Patients with IBD are more likely to have nonalcoholic fatty liver disease than the general population and tend to occur at younger ages. IBD and cholelithiasis are closely related, especially in Crohn's disease. (Korean J Gastroenterol 2019;73:248-259)

위선종, 위선암에서 Bcl-2, Bcl-xL, Bax, p53 단백의 면역조직화학 발현

이동수 ( Dong Soo Lee ),강상범 ( Sang Bum Kang ),백종태 ( Jong Tae Baek ),남순우 ( Soon Woo Nam ),이강문 ( Kang Moon Lee ),안병민 ( Byung Min Ahn ),이은희 ( Eun Hee Lee ),한석원 ( Sok Won Han ),정인식 ( In Sik Chung ) 대한소화기학회 2005 대한소화기학회지 Vol.45 No.6

Background/Aims: The aim of this study was to investigate the immunohistochemical expression of bcl-2, bcl-xL, bax, and p53 proteins according to the pathological parameters such as grade of dysplasia, histological type, depth of invasion, lymph node meta

이종 네트워크 연동 환경에서 네트워크 선택 알고리즘

우영미(Young Mi Woo),강상범(Sang Bum Kang),장영민(Yeong Min Jang) 한국통신학회 2006 한국통신학회 학술대회논문집 Vol.2006 No.7

알코올 의존 환자의 수면 장애와 하지불안증후군

이문인,정홍주,김한석,황인복,신재정,강상범,윤우상,김상훈,Lee, Moon-In,Jung, Hong-Joo,Kim, Han-Sok,Hwang, In-Bok,Sin, Jae-Jung,Kang, Sang-Bum,Yun, Woo-Sang,Kim, Sang-Hoon 대한수면의학회 2010 수면·정신생리 Vol.17 No.1

1) 알코올 의존 환자에서 불면은 68.6%의 환자들이 호소하고 있는 중요한 치료적 목표 중 하나이다. 2) 알코올 의존 환자에서의 불면과 관련된 중요한 원인은 RLS(38.4%)와 이와 흔히 동반되는 PLMD(34.9%)였다. 3) 지속되는 RLS 증상은 환자의 수면의 질적 저하를 가져오며, 불안과 같은 정서에 부정적인 결과를 가져온다. 이에 알코올 의존 환자에서 수면관련 장애들에 대한 진단적 고려와 적극적인 치료적인 접근이 반드시 필요하다. Objectives: We review the sleep problems of the alcohol dependence patients. Especially we are interested in the prevalence, the severity of symptoms, anxiety, depression, and sleep quality of restless legs syndrome (RLS) in the alcohol dependence patients. Methods: We recruit 86 alcohol dependence patients who were admitted from October 6th, 2008 to October 17th, 2008. We interviewed each patient and evaluated sleep questionnaires such as the Sleep Disorder Questionnaire (SDQ), the Pittsburgh Sleep Quality Index (PSQI) and the International Restless Legs Syndrome Study Group (IRLSSG) rating scale. The presence of RLS and its severity were assessed using the IRLSSG diagnostic criteria and the IRLSSG severity scale, respectively. Depression and anxiety were evaluated by the Beck Depression Inventory (BDI) and the Beck anxiety inventory (BAI). Results: Of all 86 patients, 59 patients have insomnia, 33 patients have RLS, 30 patients have Periodic limb movement disorder (PLMD), 29 patients have nightmare. RLS patients have more high score in the BAI ($21.70{\pm}10.36$ vs $14.67{\pm}11.98$), and their sleep quality was poor in the PSQI ($11.09{\pm}4.08$ vs $7.92{\pm}3.91$) than non-RLS patients. Conclusion: This study shows that alcohol dependence patients show many sleep problems such as insomnia and RLS. So we should notice that the sleep problems of alcohol dependence patients are important in clinical approach and treatment.