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Serum Amyloid A as a Useful Indicator of Disease Activity in Patients with Ankylosing Spondylitis
정상윤,박민찬,박용범,이수곤 연세대학교의과대학 2007 Yonsei medical journal Vol.48 No.2
Purpose: To investigate whether serum amyloid A (SAA) levels are increased in patients with ankylosing spondylitis (AS) and whether its levels correlate well with AS disease activity. Materials and Methods: Thirty-eight patients with AS and 38 age- and sex-matched control subjects were enrolled in this cross-sectional study. Their SAA levels were quantitatively measured by immunonephelometry. An established, self-administered instrument for evaluating disease activity (Bath Ankylosing Spondylitis Disease Activity Index, BASDAI) was used to measure and acute phase reactants, including erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), in patients with AS. Results: Patients with AS had a significantly higher mean SAA level than controls (9.52±7.49mg/L versus 2.73±1.57mg/L, p<0.05), and the mean BASDAI score of patients with elevated SAA levels was significantly higher than that of patients with normal SAA levels (5.6±1.3 versus 4.4±1.5, p<0.05). SAA levels showed significant correlations with BASDAI scores (r=0.431, p=0.007), ESR (r=0.521, p=0.001) and CRP levels (r=0.648, p<0.001). Additionally, the correlation between ESR and CRP levels also appeared significant (r=0.703, p< 0.001). In those with normal ESR or CRP levels, SAA levels and BASDAI scores were elevated (p<0.05) and showed a trend of positive correlation with one another. Conclusion: Our data showed that SAA levels were increased in patients with AS and correlated well with disease activity. These findings suggest that SAA can be used as a valuable indicator of disease activity in AS.
ISO 9000 인증이 품질영역들에 미치는 영향에 관한 실증적 연구
정상윤,최용정 한국컴퓨터정보학회 2003 韓國컴퓨터情報學會論文誌 Vol.8 No.1
본 연구는 ISO 9000 시리즈 인증을 획득함으로써 품질보증시스템구축 뿐만 아니라, 이미 기존 논문들에서 밝혀진 품질의식향상, 관리능력향상, 품질시스템 확립 등의 효과들로 인한 제품의 품질향상정도를 파악하기 위한 것이다.<br/> 제품의 품질향상을 확인하기 위해서 설계품질, 제조품질, 서비스품질의 향상분석뿐만 아니라 Garvin의 8가지 제품품질특성 향상분석도 이루어졌다.
디지털 전환 시범사업에 대한 평가 연구 -울진, 강진, 단양 지역을 중심으로-
정상윤 부산울산경남언론학회 2012 지역과 커뮤니케이션 Vol.16 No.1
Korea is expecting a very important business which is called Digital TV transition. For this nationwide project scheduled to be finished by December 31, 2012, not only cooperation of audiences, but also well-prepared policy is needed. However, there are many political and technical issues remained to be improved or supplemented for this conversion. For example, some studies show that people in korea have lower awareness about digital transition than people in Japan and England. Moreover, the rate of digital set-up box prevalence in Korea is not enough. This article aims at three issues to clarify. First, I studied the pilot project in three regions of Uljun, Gangjin and Danyang area researched in 2010. Second, I analyzed and evaluated the effect of the pilot project on the basis of 'in-depth interviews' and survey results with natives and chairmans of the Audiences' Support Center. Third, I suggested policy issues which need to be elaborated for the successful digital TV transition. As a result of study, I pointed out four important policy issues to be prepared by government. At first, more effective way of PR about digital TV transition has to be planned for the audiences. Second, high skilled manpower is crucial to accomplish the nationwide project. As a third, policy makers should establish policies for the 'pay-TV audiences' who are not prepared for the digital TV transition. Finally, role of KBS as a public broadcasting system is essential to reduce the fringe area. 디지털 전환은 국가적으로 매우 중요한 사업 중의 하나이다. 특히 디지털 전환을 성공적으로 완수하기 위해서는 국민들의 적극적인 협조와 정부의 치밀한 계획이 필요하다. 그러나 2012년 12월 31일 디지털 전국 전환을 앞두고 있는 지금 아직까지도 정책적으로 개선하거나 보완해야 할 사항이 많이 남아있다. 더구나 우리나라 국민들의 디지털 방송 수신기 보급률과 아날로그 방송 종료 인지율 등은 영국이나 일본에 비해 낮은 편이다. 본 연구는 울진, 강진, 단양군에서 2010년에 실시한 디지털 전환 시범사업 내용을 살펴보고, 성과를 평가 분석함으로써 디지털 본 전환에 대비하여 준비해야 할 사항들을 제시하였다. 이를 위해 시범사업이 진행되는 기간에 주민들과 시청자 지원센터장 등을 심층면접하였으며, 한국리서치에서 실시한 설문분석 자료를 참고하였다. 연구결과 난시청 해소를 위한 노력이 필요하며, 지역적 특성을 고려한 인지경로를 파악하여 보다 체계적인 홍보활동을 하는 것이 필요한 것으로 나타났다. 그리고 컨버터 지원 및 안테나를 개보수하기 위한 전문 인력을 충분히 확보해야 하며, 시청자 지원센터의 적극적인 활동을 통해 민원율을 낮추도록 하는 것이 바람직하다. 뿐만 아니라 유료방송 가입자들을 대상으로 하는 디지털 전환 정책이 마련되어야 한다. 마지막으로 성공적인 디지털 전환을 위해서는 정부, 시청자, 방송사의 역할이 중요하다. 그 중에서도 특히 KBS의 역할은 아무리 강조해도 지나치지 않는다. KBS는 국가의 기간방송으로 난시청을 해소하고 수신환경을 개선해야 하는 의무를 지니고 있기 때문이다.
정상윤,김복건,윤용달,이재성 한국유전학회 2006 Genes & Genomics Vol.28 No.1
To examine the genetic differences and similarities of two closed related individuals of the Bombina orientalis in Far East Asia, we determined the complete mitogenome sequence of Bombina orientalis from South Korea and compared the control region to that of individuals from China, as well as directly comparing the complete mitogenome sequences of those individuals. In the comparison of sequence similarity between the individuals from Korea and China, 13 protein-coding genes showed over 96% similarity, while 16S and 12S rRNA genes showed relatively lower similarities of 66% and 71%, respectively. Interestingly, a significant deletion in the control region was found in the individual from Korea, mainly due to the deletion of the tandem repeat sequence regions of the 5′ and 3′-ends.
정상윤,송창현,김연우,임업 한국지역학회 2022 지역연구 Vol.38 No.2
The purpose of this study is to explore the heterogeneity of compensating wage differentials for outdoor workers, under the threat of climate change and heatwave, by region and by wage quantile. This study conducted Oaxaca-Blinder decomposition, multiple regression analysis by region, and unconditional quantile regression analysis using the Korean Working Conditions Survey, which provides individual-level information on the working environment and worker’s characteristics. The implications derived from the results of the study are as follows: For most variables, the endowment effect and the price effect were greater for indoor workers, while experience and gender played a role in narrowing the wage gap; The compensating wage differentials for outdoor workers were confirmed to be 2.4% nationwide, depending on the region however, the compensating wage differentials varied from 5 times of national average to nothing statistically significant; The higher the wage quantile, the greater the compensating wage differentials for outdoor workers, and statistically significant monetary compensation was not identified for some low-level outdoor workers. This study is meaningful as an early study that revealed the heterogeneity of compensating wage differentials for outdoor workers and suggested further research on the topic.