림프질 전이가 있는 하인두암과 하부식도암의 진단에 활용된 내시경초음파 유도하 Trucut 생검 1예

광명옥,이정환,문정섭,김유선,류수형,총배천,김형훈,김현태 仁濟大學校 白病院 2010 仁濟醫學 Vol.31 No.-

The incidence of double primary cancer is about 10% in all kinds of cancers. Double primary cancer is usually accompanied by gastrointestinal cancer. Esophageal cancer is supposed to be frequently accompanied by squamous cell carcinoma of the head and neck or the upper respiratory tract, because of such common carcinogens as smoking and alcohol ingestion. Esophageal cancer and hypopharyngeal cancer are usually diagnosed by esophagogastric endoscopy with biopsy. We performed endoscopic ultrasound-guided Trucut biopsy(EUS-TCB) to diagnose a mediastinal mass in a 49 year-old patient, who visited our hospital because of voice change. During procedure, we accidently found enlarged celiac lymph node, and obtained tissue from the mediastinal lymph node and the celiac lymph node. We confirmed double primary cancer of squamous cell carcinoma in the esophagus and the hypopharynx via esophagogastric endoscopy.

Arachidonic acid 대사산물의 골흡수능

김형섭,오귀옥,장기완 대한구강생물학회 1991 International Journal of Oral Biology Vol.15 No.2

This experiment was performed to study the effect of the arachidonic acid metabolites(PGE_2, LTB_4, HETEs) on the bone resorption in the organ culture. The observed results were as follows: 1. PGE_2, at concentration of 10^-6M, increased ^45Ca release significantly after 72 hours of culture. 2. LTB_4 or HETEs, at all concentrations, had no effect on the bone resorption after 72 hours of culture. 3. LTB_4 or HETEs did not change the bone resorbing activity of PGE_2 bone resorption after 72 hours of culture.

치주질환에 있어서의 조직파괴인자 및 억제약물에 대한 연구

김오환,김형섭,오귀옥 대한구강생물학회 1988 International Journal of Oral Biology Vol.12 No.2

Arachidonic acid(AA) metabolites are known to play an important role in the development of inflammation and pathogenesis of periodontal disease. The bone resorbing activity of PGE_2 and elevated level of prostaglandins and thromboxane in inflamed gingiva, which are cyclooxygenase(C) products, has been well documented. However, since recent studies provide evidence that gingival tissue metabolizes AA mainly through lipoxygenase(L) pathway, we have started this study to show the exact profile of AA metabolism in gingival tissue. Fourteen individual periodontal pocket tissue(PPT) samples were obtained from patients with advanced periodontitis and incubated separately with ^14C-AA(0.2μCi). The tissue lipid extracts were separated by means of thin layer chromatography(TLC), and analyzed by means of autoradiography and TLC analyzer. Our work show that ^14C-AA metabolism in PPT is mainly via the L pathway(L products/C products=6.17) and that 12-HETE & 15-HETE(55.73% of total formed metabolites), to a lesser extent 5-HETE(6.21%), are the major L products formed. C products thromboxane B_2 (4.32%), 6-keto-PGF_1α & PGE_2 (4.42%) were also detected in much smaller amounts than L products. Indomethacin well-known C inhibitor, also inhibited L as well as C, that is the result similar to the reports of Paajanen et al.(1982) and Lessard et al.(1986). This phenomenon is being further investigated by use of partially purified L system.

악관절 융기 증강술을 통한 습관성 악관절 탈구환자의 치험례

김일규,신주호,오성섭,최진호,김형돈,오남식,김의성 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.2

Recurrent mandibular dislocation is frequent morbidity of temporomandibular joint relatively. There are many etiologic causes in TMJ disorders but, difficult to find obvious one. Various treatment methods have been utilized for a mandibular dislocation. It is categorized into two groups broadly - nonsurgical or surgical methods. The basic rationale of the surgical method is to allow free movement of the condyle by reducing height of articular eminence or to limit anterior excessive movement of the condyle by increasing height of articular eminence or soft tissue anchoring procedure. In this case, 69 year-old woman was treated by augmentation of the articular eminence with mandibular symphysial bone graft leading to osteosynthesis without difficulty. As a result, favorable postoperative outcome was obtained functionally without any complication or recurrence.

치근이개부 감염에 관한 임상적 연구

김형섭 全北大學校 齒醫學硏究所 1985 전북치대논문집 Vol.3 No.1

The author studies the incidence, age, Glickman's classification of the maxillary and mandibular molars with furcation involvement by radiographic and clinical examination. The data for this study was 369 maxillary and mandibular molars of 40 patients (male 17, female 23) of Dentistry, J.N.U. Hospital. The results were as follows. 1. The mean average age of the patients was 43. The average number of the maxillary and mandibular molars in each patient was 4.5. 2. The incidence of furcation involvement for 185 maxillary molars and 184 mandibular molars was shown in 76 maxillary molars (40%) and 79 mandibular molars (42.9%). 3. The incidence of Glickman's classification of furcation involvement was shown in 73 Grade Ⅱ, 43 Grade Ⅲ, 25 Grade Ⅳ, 14 Grade Ⅰ.

忠北地域의 배추좀나방 系統에 대한 殺蟲劑에 관한 硏究

金舜燮,李炯來 충북대학교 농업과학기술연구소 1993 農業科學硏究 Vol.10 No.2

The experiment was carried out by the spray method to investigate the insecticidal resistance of the susceptible and the collected strains of the diamondback moth, DBM(Plutella xylostella L.)in Chungbuk Province. The results are summarized as follows. 1.In Chlorpyrifos, the LC50 values(ppm) of the susceptible(s-strain), Cheongwon, Ockcheon, Boeun, Jungwon, Koesan, Yeongdong and Jewon strains were 11.5, 18.2, 39.8, 42.2, 141.6, 154.0, 173.8, and 224.9, respectively. The resistance of the Jewon strain was 19.6 times greater than that of the s-strain. 2.In Methomyl, the LC50 values(ppm) of the susceptible, Cheongwon, Boeun, Jewon, Koesan, Jungwon, Ockcheon and Yeongdong strains were 0.94, 57.1, 83.0, 97.4, 148.6, 240.8, 286.9 and 512.4, respectively. The Yeongdong strain showed the highest resistant level among the collected strains. The LC50 values of the Yeongdong, Ockcheon, Jungwon, Koesan and Jewon strains were at least 100 times greater than that of the s-strain. 3.In Carbaryl, the LC50 values(ppm) of the susceptible, Ockcheon, Boeun, Koesan, Yeongdong, Jewon, Cheongwon, and Jungwon strains were 36.3, 69.6, 141.3, 256.3, 269.9, 884.9, 2224.8 and 34 14.3, respectively. The LC50 values of the Jungwon strain was 94.1 times greater than that of the s-strain. 4.In Deltamethrin, the LC50 values(ppm) of the susceptible, Boeun, Ockcheon, Cheongwon, Yeongdong, Jewon, Jungwon, and Koesan strains were 9.3, 23.8, 30.9, 31.4, 52.0, 55.9, 67.4 and 99,6, respectively. The LC50 value of the Koesan strain was 10.7 times greater than that of the s-strain. 5.In Fenvalerate, the LC50 values(ppm) of the susceptible. Yeongdong, Jungwon, Boeun, Cheo-ngwon, Koesan, and Jewon strains were 9.7, 44.4, 72.1, 78.5, 92.0, 186.8 and 245.1, respectively. The LC50 value of the Jewon strain was 25.2 times greater than that of the s-strain. 6.In Cartap, the LC50 values(ppm) of the susceptible, Ockcheon, Koesan, Yeongdong, Jungwon, Boeun, Jewon, and Cheongwon strains were 18.5, 24.3, 25.8, 119.3, 128.5, 130.2, 132.6 and 384.0, respectively. The LC50 value of the Cheongwon strain was 20.7 times greater than that of the s-st-rain.

유리자가 치은 이식술을 이용한 부착치은 확대의 증례보고

김형섭 全北大學校 齒醫學硏究所 1983 전북치대논문집 Vol.1 No.1

To increase the attached gingiva and deepen the vestibular fornix, the author applied to use free gingival autograft procedure in the right premolar area in 43 years old male patients without systemic complication. Donor site for free gingival autograft procedure was determined to obtain upper palatal mucosa with Omar Paquett knife. Positioned the autograft and adaptedit firmly to the recipient site. Used a minimum number of sutures to avoid unneccessary tissue penetration. Grafted mucosa was covered with COE-pak for lweek and clinical evaluation was performed until 2 weeks after surgery. After postoperative 2 weeks, grafted mucosa was seen relatively normal gingival color and appeared like attached gingival architecture on clinical observation. During postoperative period, patient was no complain of the surgical site and periodontal eviornment of the patient was improved.

강릉수력발전소 발전수 방류 전후의 남대천 수질과 미생물 분포

심혜숙,김규중,김형섭,최창근,전방욱 江陵大學校東海岸地域硏究所 1993 東海岸硏究 Vol.4 No.1

강릉수력발전소의 발전수 방류가 강릉 남대천의 수질 및 미생물 분포에 미치는 영향을 조사하였다. 정점 3 상류지역의 발전수 방류는 수질에 상당한 영향을 끼쳐 정점 3 및 정점 4의 수질은 악화되고 정점 5, 정점 6 및 정점 7의 수질은 개선되었다. 미생물 분포도 이와 유사하여 정점 3 및 정점 4의 세포수는 상당히 증가한 반면 정점 5, 정점 6 및 정점 7에서는 대체적으로 감소하였다. 이 결과로 미루어보아 강릉수력발전소의 발전수는 희석효과에 의해 수질 및 미생물 분포를 변화시키는 것으로 사료된다. The effects of water discharged from Kangnung hydropower plant on the water quality and some bacterial population of Namdaecheon Stream, Kangnung were investigated. The water discharged above station 3 affected the water quality significantly; the water quality of station 3 and station 4 took a turn for the worse, however those of station 5, station 6 and station 7 changed for the better. It was also true with the bacterial population; The number of cells of bacteria increased in station 3 and 4, but the number significantly decreased in station 5, station 6, and station 7. The data suggested the idea that the water discharged from Kangnung hydropower plant changed the water quality and some bacterial population by dilution effect.

온도; pH, 염분 내성 및 충격이 개불, Urechis unicinctus 유생에 미치는 영향

최상덕,김호진,라성주,정형택,윤호섭,신종암,이원교 國立 麗水大學校 環境問題硏究所 1999 環境硏究論文集 Vol.2 No.-

The effect of different temperature, salinity and pH on survival rate of Urechis unicinctus's swimming embryo was examined to develop the method for the efficient seed production. In addition to, this study was designed to investigate the possibility of pollutant marker diagnosis of marine pollutions by the change in different temperature, salinity and pH. Treatment was carried out whit different temperature (5˚C, 10˚C, 17˚C, 20˚C, 25˚C,), salinity(0‰, 10‰, 20‰, 30‰, 34‰, 40‰) and pH(4, 6, 7.2, 8.2, 9.2, 10). All the swimming embryo of the temperature experiment was survived within all experiment section, but the others experiment were not. At the temperature-shock and tolerance experiment ranging from 5˚C to 25˚C the survival rate was occurred: 75%, 95%, 100%, 100%, 50%, at the ph-Shock experiment ranging from 4 to 10, the survival rate was occurred: 0%, 50%, 85%, 100%, 60%, 0%, at the pH-tolerance experiment ranging 4 to 10 the survival rate was occurred : 0%, 75% 90%, 100%, 80%, 0%, and at the salinity-shock experiment ranging from 0% to 40% the survival rate was occurred : 0% 10% 90% 95% 100% 0% , at the salinity-tolerance experiment ranging from 0% to 40% , the survival rate was occurred : 0% 0% 90% 100% 100% 0%. These results suggest, that the survival rate of larvae of Urechis unicinctus was the highest at 17˚C, 34%. pH8.2 and this Urechis unicinctus could be live at the zone of euryceious and zone of euryhalines

도암호의 수화현상과 환경요인분석

전방욱,김형섭,김형근 강릉대학교동해안지역연구소 1993 東海岸硏究 Vol.4 No.3

수화를 일으키는 원인종을 찾고, 수화에 미치는 각각의 환경요인의 영향을 밝히기 위하여 요인분석을 시도하였다. 수화를 일으키는 원인종은 Microcystis aeruginosa로 밝혀졌다. 제1요인은 식물성 플랑크톤에 의한 수화와 관계가 있었는데 이는 엽록소 a에 대한 인자부하량이 +0.93으로 나타났기 때문이다. 식물성 플랑크톤은 호소표층수에서 인을 소모시키는 것으로 나타났으며 pH, 부유물질량, 탁도등을 증가시켰다. 제2요인은 유기오염과 관계가 있었는데 이는 생물화학적 산소요구량과 대장균군수의 인자부하량이 각각 +0.68과 +0.78로 나타났기 때문이다. The water bloom forming species were investigated, and factor analysis was applied to scrutinize the influence of different environmental factor on water blooming. The water bloom forming species was identified as Microcystis aeruginosa. The first factor was phytoplankton blooming, because it has positive loadings for chlorophy11 a (+0.93). It showed that phytoplankton cause deprivation of phosphorus from lake surface water and increases of pH, suspended solid and turbidity. The second factor was organic pollution because it has positive loadings for biochemical oxygen demand (+0.68) and MPN (+0.78).