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      • 척수압박으로 발현된 급성 골수성 백혈병에 동반된 과립구성 육종 1 례

        윤상준,김영곤,김희종,박유환,정춘해,김양수,김태균,박영진,전호종 조선대학교 부설 의학연구소 2000 The Medical Journal of Chosun University Vol.25 No.1

        저자들은 척수압박으로 하지마비를 보인 환자에서 수술 후에 급성 백혈병에 동반된 과립구성 육종으로 진단된 환자 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Granulocytic sarcoma(GS) is an uncommon tumor composed of immature cells of the granulocytic series. Most case of GS occur in the course of acute leukemia and the blast crisis of chronic leukemia, Rarely, however, it may present before leukemia becomes clinically apparent. It may also occur in patients with myeloproliferative disoders. GS has been reported that it occurs in 3% to 9% of patients with acute myelogenous leukemia(AML) and the incidence of GS is reported to be higher in patients with t(8;21). GS occurs relatively commonly in africa and has been reported to affect 10-25% of black children presenting with AML. This is very rare case of granulocytic sarcoma with AML(FAB M5) presented with spinal cord compression which was supported by decompression laminectomy.

      • 분말충진방법과 가공정도에 따른 Ag/BSCCO 초전도선재의 특성

        지봉기,김태우,김정호,김중석,주진호 成均館大學校 科學技術硏究所 1998 論文集 Vol.49 No.1

        We evaluated the effects of processing variables on interface irregularity. microstructure. and resultant Jc of BSCCC superconductor tape. For the tapes made by PIT technique. the degree of interface irregularity was varied with powder packing methods and forming process variables. It was observed that the degree of interface irregularity of the tape by CIP method was more reduced. compared to that of the tape by ram method. In addition. the degree of interface irregularity was promoted with decreasing the dimension of tape during forming process. As the dimension of wire/tape were changed from diameter of 3.25mm to thickness of 200㎛ during forming process. Jc value was observed to be increased by 10 times. It was likely that the improvenment of Jc was mainly result from the enhanced texturing of 2223 grain. Microstructural investigation showed the degree of texturing was degraded by the existence of both second phases and interface irregularity. If the interface was flat, larger grain size and better texturing near interface were developed compared to those inside superconducting core, The improvements of microstructure near interface may be result of reaction between Ag and superconductor phase.

      • 상태공간모형추정의 Akaike방법과 Aoki방법의 효율성 비교

        김혜중,신호중,김명철 동국대학교 자연과학연구원 1995 자연과학연구 논문집 Vol.15 No.-

        Among the several state space model building in time series, we investigate the forecasting ability of the Akaike method of model estimation and Aoki's method. There are important differences between two model estimation. Akaike uses the normalized Hankel matrix to extract state vector, while Aoki's method does not. In order to compare the efficiency of two method, we exploit the Monte Carlo approach for the several simulate multivariate co-related time series model.

      • SOL-GEL法에 依한 LAS系 結晶化유리의 製造에 있어서 租成比유리의 特性에 미치는 影響

        김봉걸,양중식,조훈성,권창오,박경호 慶熙大學校 材料科學技術硏究所 1990 材料科學技術硏究論集 Vol.3 No.-

        The purpose of this study is to investigate into the physical properties of Li₂O-Al₂O₃-nSiO₂ (LAnS) system of crystallized glass prepared by sol-gel method according to the composition ratio of LAnS. In order to find the crystallization temperature as well as the state of crystalline, differential thermal analysis and X-ray diffraction analysis were examined. The results obtained are as follows : 1. Gelling time became longer as increasing the composition ratio of SiO₂ and also found that it became faster as increasing the additive amount of water. Also, additive amount of water required for the gellation was above four times of the theoretical amount of water required hydrolysis. 2. Surface area and mean pore size became larger as increasing the composition ratio of SiO₂ and for LA4S dried gel, surface area was 331.1m^(2)/g, mean pore size distributed about 5nm and 30-50nm. 3. The crystallization temperature is high as increasing the composition ratio of SiO₂ and for LA4S, crystallization temperature is 800℃. Also, LA4S formed at 800℃ for the crystalline phase of β-eucryptite and at 900℃ for crystalline phase of β-spodumene.

      • KCI등재

        동적계획모형을 이용한 근무형태 결정

        김중순,안봉근,손달호 한국경영과학회 2003 經營 科學 Vol.20 No.2

        In this paper, we applied dynamic programming to determining work schedule type. In dynamic programming formulation. each day during a planning horizon represents a stage for which a decision Is made. The alternatives are given by work schedule types that combine regular time, overtime. additional shift, and so on. In this case, their associated return function is labor cost. The state is defined as the amount of work time allocated to stage 1, stage 2, …, and current stage. A case study for a real manufacturing company was performed to apply dynamic programming to scheduling daily work hours during a week. The case study showed that total cost of our solution derived from dynamic programming decreased by about 6% as compared with the solution obtained from the previous method.

      • KCI등재

        수지상세포의 방사선 저항성에 대한 연구

        김은실,김종순,이명호,범희승,민정준,정환정,김성민,허영준,송호천,이제중 대한핵의학회 2003 핵의학 분자영상 Vol.37 No.3

        목적 : 림프구와 비교되는 수지상 세포의 방사선 민감성을 보기 위하여 본 연구를 시행하였다. 대상 및 방법 : 말초혈액에서 분리한 T 림프구에 0 Gy, 10 Gy, 30 Gy의 방사선을 조사하고 4시간 후에 유세포 분석기를 이용하여 선량별 세포고사 빈도를 관찰하였다. 또한 조혈모세포에서 미성숙 및 성숙 수지상 세포를 단계적으로 분리 배양하여 각각 0 Gy, 10 Gy, 30 Gy, 100 Gy의 방사선을 조사하고 4시간, 24시간 그리고 48 시간 후에 선량별 세포고사 빈도를 관찰하였다. 사이토스핀(cytospin)슬라이드에 림프구와 미성숙 및 성숙 수지상세포를 3×104개 씩 분주하고 May Grunwald-Giemsa 염색한 후, 광학 현미경 하에서 각각의 세포군 당 100개의 세포에서 세포 면적당 핵의 면적 비를 측정하였다. 결과 : 림프구에서는 방사선조사 선량별로 세포고사 빈도가 유의하게 증가하였으나, 수지상 세포에서는 그 분화정도나 방사선조사 선량에 따른 세포고사의 빈도차이가 없었다. 또한 수지상 세포는 방사선선량과 관계없이 용량에 의존적으로 강력한 T-세포 자극능을 보였다. 림프구의 세포에 대한 핵의 면적 비는 미성숙 및 성숙 수지상세포의 세포에 대한 핵의 면적 비보다 현저히 큰 반면, 두 가지 수지상세포간에 유의한 차이는 없었다. 결론 : 수지상세포는 그 분화도와 상관없이 림프구에 비하여 방사선 저항성을 나타내었고, 이는 세포의 형태적 차이에 따른 표적의 크기와 관련이 있을 것으로 생각되며, 향후 분자 생물학적인 연구의 기초 자료로 활용할 수 있을 것으로 생각된다. Purpose : To evaluate radiation sensitivity of dendritic cells in comparison with lymphocytes. Materials and methods : T lymphocytes captured from peripheral blood were irradiated by 0 Gy, 10 Gy, 30Gy. Apoptosis was measured by flowcytometry for staining of Annexin V 4 hours after irradiation. Immature and mature dendritic cells processed from blood hematopoietic stern cell were irradiated by 0 Gy, 10 Gy, 30 Gy, 100 Gy respectively and apoptosis was measured by flowcytometry with time difference as 4h, 24h and 48h after irradiation. Morphometric analysis by percent nucleus was measured in three cell groups, also. Results : Lymphocytes showed radiation sensitivity by increasing apoptotic fraction according to radiation dose. However, both mature and immature dendritic cells showed consistent fraction of apoptosis in spite of increasing radiation dose. Percent nucleus ratio is significantly higher in lymphocytes than that of mature or immature dendritic cells. Stimulation of T-cell by dendritic cells was not changed after irradiation. Conclusion : Dendritic cells showed radioresistance which was associated with small size of nucleus in comparison with lymphocytes and this result would be used as a basal data of radio-labelling for the cellular trafficking studies in nuclear medicine fields.

      • BA, NAA, 2,4-D 및 배지의 무기물 농도가 포도의 기내 생장에 미치는 영향

        金善圭,全盛皓,李重燮 충북대학교 농업과학기술연구소 1997 農業科學硏究 Vol.14 No.-

        Shoot tip and node segments derived from cuttings of two grape cultivars (Aramon, Aligote) were cultured in vitro on full - and one half strength MS media supplemented with BA, NAA, and 2,4-D alone and in combination, and the growth was investigated. Full strength, shoot tip, and NAA enhanced the shoot growth. BA alone and/or in combination with NAA was favorable for shoot multiplication regardless of media strength and bud position. Varietal differences were recognized in callus formation in favor of Aramon, and all growth regu-lators, especially BA+ NAA+2,4-D, were effective for callus formation in Aramon. Bud position ef-fect was negligible but half stremgth media was more effective. In Aligote, 2,4-D was most effective for callus formation regardless of media strength.

      • KCI등재

        계층분석기법을 이용한 하수관거 결합항목별 가중치 산정

        김응석,이정호,김중훈 대한상하수도학회 2003 상하수도학회지 Vol.17 No.2

        In domestic sewer rehabilitation works, the numerical weighting based on number of sewer defect is used to determine the propriety of rehabilitation order. In case of the decision standard in each defect contents of inside and outside of the country, the weight for determining sewer rehabilitation order is composed of several distribution of marks, not considering the weight in each sewer defects. In this study, the fifteen defect contents are determined suitable for domestic situation based on the sewer defect data of inside and outside of the country. Also, we select persons in charge of the business to calculate the detail weight and pose questions about important level of each sewer defect contents. The results of using Delphi method which is a question survey method apply the AHP and calculate the weight in each sewer defect. The appropriate marks matrix of sixteen sewer defects is made for laying precise decision standard of sewer condition through the result of analysis. The marks matrix of sixteen sewer defects can solve the complicated decision making problems of sewer rehabilitation works.

      • 체외형 자동 제세동기(AED)와 심전도계(ECG)를 위한 통신 프로토콜의 설계 및 사용자 인터페이스 구현

        김남훈,권희중,권호열,나학록 江原大學校 産業技術硏究所 2004 産業技術硏究 Vol.24 No.A

        In this paper, we studied Automated External Defibrillator and Electro- Cardiogram System. Proposed System, CU-EX1, is a PC-based AED/ECG system that manages the data acquired by Paramedic CU-ER1. The system controls the transfer of data from the Paramedic CU-ER1 and the storage of the data in a local host computer. Patient data could be entered as soon as the rescue data is stored in a local computer. The system also displays the data on a local computer and facilitates review of rescue events.

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