격물구와 상용 간접구의 온열자극 비교 연구

장민기,김은정,정찬영,윤은혜,황지후,김갑성,최인화,이승덕 대한침구의학회 2010 대한침구의학회지 Vol.27 No.3

Backgrounds : Recently, commercial indirect moxibustion has been widely used as a substitute for traditional indirect moxibustion by clinicians due to its convenience in using. But, there has been lack of studies about the similarity of thermal stimulation between commercial indirect moxibustion and traditional indirect moxibustion. Objectives : To demonstrate commercial indirect moxibustion can substitute for traditional indirect moxibustion by comparing thermal stimulation between the two. Methods : We measured bottom temperature of commercial indirect moxibustion and traditional indirect moxibustion with various thicknesses of ginger and garlic. A clinical trial was performed on 18 healthy subjects to evaluate thermal stimualtion. The subjects were randomly assigned into two groups, traditional indirect moxibustion with ginger and garlic. The skin temperature and heating time were measured. They received moxibustion therapy with commercial indirect moxibustion and traditional indirect moxibustion according to their groups. Acupoint Chogcoe(LU6), Zusanli(ST36) and Tianshu(ST25) were used in each group for 3 times. Results : There was no difference in bottom temperature among commercial indirect moxibustion, traditional indirect moxibustion with 2㎜ ginger and 3㎜ garlic. No major difference was detected in the subjects’ baseline data. There was no difference in skin temperature and heating time among these 3 type of moxibustions. Also, No major difference was detected in VAS score of thermal stimulation and frequency of burns among these 3 type of moxibustions. But, most subjects regarded their sensation weren’t identical because of its own distinct characteristics. Conclusions : Commercial indirect moxibustion, traditional indirect moxibustion with 2㎜ ginger and 3㎜ garlic have same thermal stimulation. Thus, commercial indirect moxibustion can substitute for traditional indirect moxibustion.

隔物灸의 隔物 특성에 따른 온열자극 비교연구

왕개하,김은정,조현석,김갑성,이승덕,김경호 대한침구의학회 2012 대한침구의학회지 Vol.29 No.5

Objectives : Indirect moxibustion is one of the thermotherapy in Korean medicine and buffer of ginger and mankshood slice are common materials to be used. However it is difficult to control the power of thermal stimulation and the stimulation is greatly influenced by the characteristic of buffer. So we research on the buffer characteristic of indirect moxibustion according to the thickness, diameter and water content changes. Methods : We used thermocouples to measure temperature from surface to depth of 2, 4, 6, 8, 10, 12, 14㎜ on tissue model and calculated peak temperature(℃). The data were analyzed with student t-test and one-way ANOVA(p<0.05). Results : 1. The peak temperature of indirect moxibustion with ginger were determined by thickness of ginger slice and temperature changes according to the thickness at intervals of 1㎜ but according to the diameter at intervals of 4㎜. 2. The peak temperature of indirect moxibustion with mankshood were determined by thickness of mankshood slice also. The peak temperature of mankshood moxibustion was higher than that of ginger moxibustion. 3. In this study, 2㎜-thick-ginger slice and 3㎜-thick-mankshood slice were suitable for indirect moxibustion. Variation in the thickness of which is more efficient to control the power of thermal stimulation on indirect moxibustion. 4. The more water loss we got on ginger slice, the higher peak temperature we measured at the surface of moxibustion. But the thermal stimulation was not conducted more than 2㎜ in the depth. 5. The thickness and water content of buffer are important in indirect moxibustion. Conclusions : The temperature of indirect moxibustion depends on the thickness of buffer than the diameter of it. Therefore, it is more efficient according to the thickness of buffer so that we control the power of thermal stimulation. And water content of buffer is one of the important factor in indirect moxibustion.

간접구 시술이 골격근 Adiposity 유발 쥐의 근육조직에 미치는 영향

이기수,홍권의 대한침구의학회 2014 대한침구의학회지 Vol.31 No.1

Objectives : To observe the regenerative effects of indirect moxibustion, a traditional Korean medical treatment on skeletal muscles using mouse model of skeletal muscle adiposity. Methods : Twenty seven ICR male mice were randomly assigned into Intact control(n=3), glycerol treatment together without moxibustion(n=12), and glycerol treatment together with moxibustion (n=12) groups. Mice of glycerol treatment groups were injected with 50 ${\mu}l$ DW(distilled water) containing 50 % of glycerol into the two tibialis anterior. After injection, moxibustion was applied at 'Shenshu'($BL_{23}$) and 'Zusanli'($ST_{36}$) acupoints three times per each session, every days for twelve days(total 12 treatments). Phospho-Erk1/2, Myostatin protein levels were analyzed by western blotting and immunofluo-rescence staining techniques for tissues of the tibialis anterior muscle. Smad, phospho-Smad were analyzed by immunofluorescence staining. Results : 1. Histological analysis of sections from injected TA muscles showed that glycerol induced rapidly muscle necrosis, with a maximum at day 3. 6 days and 9 days after injection, muscle was regenerating. 2. According to western blotting and immunofluorescence staining, phospho-Erk1/2 protein signals in glycerol treatment with moxibustion group were stronger compared to Intact and glycerol treatment without moxibustion group. 3. According to western blotting and immunofluorescence staining, myostatin protein signals in glycerol treatment without moxibustion group were stronger compared to Intact and glycerol treatment with moxibustion group. 4. According to immunofluorescence staining, Smad protein signals in glycerol treatment without moxibustion group were stronger compared to Intact and glycerol treatment with moxibustion group. 5. According to immunofluorescence staining, phospho-Smad protein signals in glycerol treatment without moxibustion group were stronger compared to Intact and glycerol treatment with moxibustion group. Conclusions : These results confirm that indirect moxibustion of 'Shenshu'($BL_{23}$) and 'Zusanli'($ST_{36}$) influences muscle regeneration in mouse models of skeletal muscle adiposity. Further discussion, and the establishment of moxibustion mechanism will prompt clinical application of moxibustion.

염(鹽)의 종류(種類)에 따른 격염구(隔鹽灸)의 열전달(熱傳達) 특성(特性)에 관한 실험적(實驗的) 연구(硏究)

이건목,이건휘,서은미,Lee, Geon-mok,Lee, Gun-hyee,Seo, Eun-mi 대한침구의학회 2004 대한침구의학회지 Vol.21 No.1

Objective: The purpose of this study is to investigate the mechanism and effect of moxibustion with salt objectively, to be used as the quantitative data through the measurement of temperature, and to grasp the thermodynamic characteristics of moxibustion with salt. Methods: We have selected of the moxibustion with salt of indirect moxibustion. We make a comparative study of the thermodynamic characteristics of moxibustion with salt as a kind of the 4 salt. We examined combustion times, temperatures, temperature gradients in each period during a combustion of moxa. Results: 1. We make out that it is not significantly change the time of thermal conduction of moxibustion with salt as a kind of 4 salt. 2. The heating period of Refined Salt was long and that of Sun-dried Salt was a short time respectively. The heating period of maximum tamperature is high Sun-dried Salt, Mechanical Salt and Refined Salt orderly. Maximun heating speed in the heating period was $0.151{\sim}0.184^{\circ}C/sec$ and at the same tendency of the maximum temperature in the heating period. 3. The retaining period was shorter than the heating period respectively, that is 15~24% of the combustion time of in the heating period. We make out that it is not significantly different the time of the retaining period as a kind of 4 salt. The mean temperature of retaining period was $43.2{\sim}48.1^{\circ}C$, that was extraordinarily high temperature. 4. We make out that it is not significantly different the time of the cooling period as a kind of 4 salt. The cooling period was measured 223~233sec. Beacuse the same density and size of moxa combustion was made an experiment. 5. The effective combustion time of Refined Salt is longer(259sec) than that of Sun-dried Salt(173sec). It is significantly different the time of the combustion time as a kind of 4 salt. 6. It is significantly different the Sample deviation of the combustion time as a kind of 4 salt because of the water content of the 4 salt individually. Conclusions: As the base on this study, we obtained the conclusion as the follows. The salt of moxibustion with salt was fitted for Sun-dried Salt due to making to Mechanical Salt recently. The Refined Salt is composition rate to another and small size comparatively. So It was fitted for the salt of moxibustion with salt. It is necessary to study continuously about the more suitable moxibustion with salt and quantitative analysis about the moxibustion with salt.

피부 열전도 온도에 근거를 둔 거짓 뜸 개발 및 평가 연구

장민기,윤은혜,정찬영,변혁,김은정,김경호,김갑성,이승덕 대한침구의학회 2010 대한침구의학회지 Vol.27 No.1

Background : To demonstrate the efficacy of moxibustion therapy, randomized controled trials are required. But, clinical trials of moxibustion had limitations due to the absence of a sham moxibustion model for an appropriate placebo. Objectives : To develop a new sham moxibustion model based on the thermal characteristics of commercial indirect moxibustion, especially temperature, and to evaluate whether it could be applied in clinical trials. Methods : By applying heat insulation, we created a sham moxibustion device that was indis- tinguishable from a real one with the naked eye. It also stimulated heat but had inert remedial value. A clinical trial was performed on subjects to test double blinding. The subjects were randomly assigned into two groups, a treatment group and a sham group. Acupoint Zusanli(ST36) was used in each group for 3 times. A sham acupuncture credibility questionnaire was modified into a moxibustion credibility questionnaire and was filled out after treatment. Results : No major difference was detected in the subjects’ baseline data. Most subjects and practitioners could not distinguish the sham moxibustion device from the real one. But, subjects who had experience of moxibustion therapy more likely to distinguish the sham moxibustion device from the real one than subjects who didn’t have experience of moxibustion therapy. The treatment group showed a significant difference in the VAS(Visual Analog Scale) for intensity of sensation during treatment than that of the sham group. Conclusions : The sham moxibustion device in this study is proved sufficient and credible to be applied in investigations of the effect of moxibustion. But it is more appropriate for the people who don’t have experience of moxibustion therapy.

격강구(隔薑灸)의 연소(燃燒) 특성(特性)에 관한 실험적(實驗的) 연구(硏究)

이건목,이건휘,문성재,황병천,국우석,장지연,김양중,장재호,윤주영,Lee, Geon-mok,Lee, Geon-hui,Moon, Sung-jae,Hwang, Byung-chun,Guk, Uo-suk,Jang, Ji-yeon,Kim, Yang-jung,Jang, Jae-ho,Yun, Ju-young 대한침구의학회 2004 대한침구의학회지 Vol.21 No.3

Objective : The purpose of this study is to investigate the mechanism and effect of moxibustion with ginger objectively, to be used as the quantitative data through the measurement of temperature, and to grasp the thermodynamic characteristics of moxibustion with ginger. Methods : We have selected the indirect moxibustion with ginger among many indirect moxibustions. We produced a slice of ginger to a thickness of 3, 4, 5mm and the moxa cone having a diameter of 8mm, a height of 10mm for making a comparative study of characteristics of moxa cone according to change the density. We have made a comparative study of the thermodynamic characteristics of moxibustion with ginger with or without holes. We measured combustion times and calculated temperatures, temperature gradients in each period during a combustion of moxa. Results : 1. We found out it was not significantly influenced by the existence of the punched holes in a slice of ginger because the punched holes grow smaller immediately. 2. The duration of the preheating period became longer according to thickness of a slice of ginger and was not directly proportional to the density of moxa cone. The duration of the preheating period was extremely short when it burned a 100mg moxa cone. That was influenced by the density of moxa cone. 3. The duration of the heating period became longer according to thickness of a slice of ginger likewise the preheating period bacause the density of moxa cone had effected on the combustion characteristics. The duration of the heating period was extremely long when it burned a 100mg moxa cone. On the other hand the maximum temperature in the heating period was appeared that the combustion with a thin slice of ginger was highest and measured that the large density of moxa cone was higher. But the maximum temperature in the heating period was about $37.8^{\circ}C{\sim}44.2^{\circ}C$respectively lower in others. 4. The duration of the retaining period was some doubling shorter than that of the heating period that is concerned the shape of moxa cone. The temperature measured the close of a retaining period was $36.6^{\circ}C{\sim}41.8^{\circ}C$, that was considerably lower temperature. 5. The mean ascending temperature velocity and the mean descending temperature velocity were $0.042{\sim}0.073^{\circ}C/sec$, $-0.027{\sim}-0.064^{\circ}C/sec$ respectively. Then, the ascending temperature velocity was some faster than the ascending temperature velocity. Conclusions : The quantitative standard for obtaining the effective heating stimulation is that if the slice of ginger made a hole in it, we had to use the needle above 1.5mm diameter. The recommended size of a slice ginger is the 14mm diameter and the 2~3mm thickness. The moxa cone is formed the conical shape that the base diameter was 8mm, the height was 10mm, the density was $600mg/cm^2$.

상용 간접구의 규격과 품질균일성에 대한 조사

권오상 ( O Sang Kwon ),이상훈 ( Sang Hoon Lee ),조성진 ( Sung Jin Cho ),최광호 ( Kwang Ho Choi ),연선희 ( Sun Hee Yeon ),이새봄 ( Sae Bom Lee ),최선미 ( Sun Mi Choi ),류연희 ( Youn Hee Ryu ) 경락경혈학회 2011 Korean Journal of Acupuncture Vol.28 No.3

Objectives : Burn is most common adverse events of moxibustion. Various kinds of components influence on the heat stimulation of commercial indirect moxa, but there are not enough investigation about the status. The purpose of this study is to investigate the 6 components to build a base data that is currently available to build a standard of an indirect moxibustion. Methods : The length and weight, density, thickness of the paper disk, diameter of the paper disk, and diameter in the paper disk hole were measured against 6 kinds of commercial indirect cautery. Results : 1. ``Seoam``, ``Kihwang`` and ``Taegeuk`` shows uniform length than the other brands. 2. ``Dongbang``, ``Kihwang`` and ``Taegeuk`` shows uniform weight than the other brands. 3. ``Dongbang``, ``Kihwang`` and ``Taegeuk`` shows uniform density than the other brands. 4. ``Dongbang`` and ``Kihwang`` shows uniform thickness than the other brands. 5. ``Seoam``, ``Dongbang`` and ``Taegeuk`` shows uniform diameter of disc hole than the other brands. Conclusions : As a result of investigation, ``Dongbang`` and ``Kiwhang`` indirect moxibustion was identified as a uniform product. This results are considered as an important base materials of the KS through commercial indirect moxibustion.

灸法의 표준화를 위한 온도 측정 硏究

김윤홍,이승호,여수정,최일환,김영곤,임사비나 대한침구의학회 2008 대한침구의학회지 Vol.25 No.2

Objectives : The moxibustion is the method in using the heat stimulation made of attached and burned a moxa or other herbal materials on a healing point or acupuncture point and the chemical stimulation of a resin made from burning them. We need to standardize the characteristics of moxa combustion in order to get more systematic and objective result in operation mechanism and effects and then get more clinical abilities in these fields. Methods : In this study, using of labview system on the moxibustion. 1. we studied relation the size of barley and jujube seed with the moxa cone’s peak combustion tempera- ture and then measured and compared the moxa cone’s peak combustion temperature by tonification and sedation method. 2. we measured the peak combustion temperature of indirect moxibustion. Results & comclusions : 1. When we measured a direct moxibustion’s combustion temperature, the jujube seed sized moxa cone’s peak temperature was higher than the barley sized moxa cone’s when it burned and the time to peak temperature of the barley sized moxa cone was shorter than the jujube seed sized moxa cone’s. 2. When the direct moxibustion was burned by the tonification and sedation method, the sedation method’s peak temperature was higher than the tonification method’s, the tonification’s time to peak temperature was shorter than the sedation method’s. 3. When we measured the temperature of the moxa combustion in the kinds of sliced herbal materials, the peak temperature of indirect moxibustion with a ginger when it sliced a 1.3㎜ size and a 1.5㎜ size was degreed within 40℃ to 52℃ and the peak temperature of indirect moxibustion with a garlic when it sliced a 1.7㎜ size was degreed within 46℃ to 62℃.

급성 족관절 염좌에 대한 침구병행 치료와 침 단독 치료 효과의 비교 연구

우창훈 ( Chang Hoon Woo ),권오곤 ( O Gon Kwon ),안희덕 ( Hee Duk An ) 한방재활의학과학회 2010 한방재활의학과학회지 Vol.20 No.1

Objectives :The purpose of this study is to compare with the effect of acupuncture treatment with or without indirect moxibustion treatment for acute ankle sprain. Methods :This study was carried out on the 48 patients who had been treated for acute ankle sprain from June 1st to November 30th 2009 in the Dept. of Oriental Rehabilitation, Pohang Oriental Medical Hospital, Daegu Hanny University. The patients were divided into 3 groups ; Group A took near acupuncture point needling, Group B took remote acupuncture point needling, Group C took remote acupuncture point needling with indirect moxibustion. 3 Groups had been co-treated with rest, ice, compression and elevation(RICE) therapy, physical treatment and administered Ojeok-san(Wuji-san) extract granule. To evaluating the efficiency of each treatment, Ankle-Hindfoot Scale(AHS) and Visual Analogue Scale(VAS) were applied before treatment and after 3rd treatment. Results :In results, the AHS scores were increased and the VAS scores were decreased after 3rd treatment in all group. Also, AHS scores and the VAS scores of intergroup were showed no significant change. Conclusions :In this study, there is no significant effect between only acupuncture treatment and moxibustion co-treatment for acute ankle sprain.

마늘뜸의 연소특성에 관한 연구

이건목,이건휘,조남근,박소영,Lee, Geon-mok,Lee, Geon-hyee,Cho, Nam-geun,Park, So-young 대한침구의학회 2004 대한침구의학회지 Vol.21 No.4

Objective: The propose of this study is to investigate the characteristics of combustion in indirect moxibustion with garlic. Methods: We observed the characteristics of combustion by the variations of the thickness(3mm, 4mm, 5mm) of a slice for indirect moxibustion with garlic and mass(80mg, 100mg, 120mg) of moxa cone and existence of holes. The temperature of indirect moxibustion for garlic insulation with holes was higher than temperature of indirect moxibustion for garlic insulation without holes. Combustions time in the preheating period is about 1 minute, it varies by the existence of holes, the thickness of a slice for indirect moxibustion with garlic, and the density of moxa cone. Results: Maximum temperature of heating period was $38.7{\sim}46.2^{\circ}C$, combustion time in the heating period was 118~164sec and maximum ascending temperature gradient was $0.102{\sim}0.264^{\circ}C/sec$. Retaining period was shorter than heating period and stimulus of heating retains more, because it is higher than body temperature. By this report, indirect moxibustion with garlic is more effective with holes and the appropriate thickness of a slice for indirect moxibustion with garlic is 3.5~4mm. It is appropriate that the diameter of moxa cone is 8mm and height of that is 10mm. With this condition, effective combustion period is 120sec, maximum temperature is $42{\sim}44^{\circ}C$, maximum ascending temperature gradient is $0.14{\sim}0.16^{\circ}C/sec$. It is necessary to study clinical correlations for more accurate quantitative standard.