Original Articles : Clinical significance of occult hepatitis B virus infection in chronic hepatitis C patients

( Jae Young Jang ),( Soung Won Jeong ),( Sung Ran Cheon1 ),( Sae Hwan Lee1 ),( Sang Gyune Kim ),( Young Koog Cheon ),( Young Seok Kim1 ),( Young Deok Cho1 ),( Hong Soo Kim ),( So Young Jin ),( Yun Soo 대한간학회 2011 Clinical and Molecular Hepatology(대한간학회지) Vol.17 No.3

Background/Aims: We investigated the frequency of occult hepatitis B virus (HBV) infection in anti-hepatitis C virus (HCV)-positive individuals and the effects of occult HBV infection on the severity of liver disease. Methods: Seventy-one hepatitis B virus surface-antigen (HBsAg)-negative patients were divided according to their HBV serological status into groups A (anti-HBc positive, anti-HBs negative; n=18), B (anti-HBc positive, anti-HBs positive; n=34), and C (anti-HBc negative, anti-HBs positive/negative; n=19), and by anti-HCV positivity (anti-HCV positive; n=32 vs. anti-HCV negative; n=39). Liver biopsy samples were taken, and HBV DNA was quantified by real-time PCR. Results: Intrahepatic HBV DNA was detected in 32.4% (23/71) of the entire cohort, and HBV DNA levels were invariably low in the different groups. Occult HBV infection was detected more frequently in the anti-HBc-positive patients. Intrahepatic HBV DNA was detected in 28.1% (9/32) of the anti-HCV-positive and 35.9% (14/39) of the anti-HCV-negative subjects. The HCV genotype did not affect the detection rate of intrahepatic HBV DNA. In anti-HCV-positive cases, occult HBV infection did not affect liver disease severity. Conclusions: Low levels of intrahepatic HBV DNA were detected frequently in both HBsAg-negative and anti-HCV-positive cases. However, the frequency of occult HBV infection was not affected by the presence of hepatitis C, and occult HBV infection did not have a significant effect on the disease severity of hepatitis C. (Korean J Hepatol 2011;17:206-212)

한약에 의해 유발된 급성 간질성 신염 2례

김덕윤,박동건,김응석,강영모,양창헌,이정호,이동철,이영현,김정란 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

간질성 신염은 신장의 간질을 선택적으로 침범하는 염증성 질환으로 여러가지 원인에 의해 유발되며, 이 중 약물에 의한 경우는 각종 항생제, 비스테로이드성 진통제, 항경련제, 이뇨제, 면역억제제등에 의한 증례들이 보고되고 있다. 현재 각종 질환-특히 만성질환-의 치료에서 한약이 차지하는 비중이 적지 않으나, 그 각각의 성분들이 유발할 수 있는 부작용들에 대한 연구는 거의 없는 실정이다. 저자들은 관절염 치료를 위해 중국산 한약을 복용한 후 복통, 피로감 및 육안적 혈뇨를 주소로 내원한 두 환자에서, 단백뇨와 신기능 장애를 보여 시행한 신조직 생검상 급성 간질성 신염에 합당한 병리학적 소견을 보이고, 한약 복용 중지 후 급속한 회복을 보여, 한약에 의해 유발된 것으로 사료되는 급성 간질성 신염 2예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Acute interstitial nephritis is a disease characterized by renal interstitial inflammatory cell infiltration and acute renal functional deterioration. This is caused mainly by antibiotics, NSAID and diuretics such as thiazide, but cases induced by herb medication are rare. We experienced two cases of acute interstitial nephritis after treatment with herb medication. One 71-year-old female patient and the other 60-year-old female were admitted to the hospital because of general weakness and gross hematuria. Microscopic hematuria, pyuria, and proteinuria were presented. After definitive diagnosis with a renal biopsy, we noted rapid recovery of renal function by drug withdrawal and steroid therapy. We report these cases with a review of the referenced literatures. Key Words : Herb medication, Acute Interstitial nephritis.

전통누룩 진균류를 이용한 입국의 제조 및 입국곰팡이의 동정

김재호 ( Jae Ho Kim ),권영희 ( Young Hee Kwon ),이애란 ( Ae Ran Lee ),김혜련 ( Hye Ryun Kim ),안병학 ( Byung Hak Ahn ) 한국균학회 2012 韓國菌學會誌 Vol.40 No.4

Various koji were prepared by fungi isolated from traditional nuruk and their quality characteristics were investigated. Acidity and saccharification power of their koji were ranged in 5.0~6.8 and 128sp~241sp. Nine fungi which were showed good quality and sensory evaluation were identified by analysis of their nucleotide sequences with PCR-amplified 18S rDNA internal transcribed spacer-1(ITS-1) and ITS-4 genes. Among them, six strains were identified as Aspergillus oryzae and the other strains were identified as Mycocladus corymbiferus, Rhizopus oryzae, Lichtheimia corymbifera.

四分法과 K.D.C.의 比較

이영란 明知大學校 圖書館學科 1987 圖書館學論集 Vol.1 No.1

도로 노면의 형상과 강우의 임계 지속시간을 고려한 적정 우수 유출량 산정 및 영향분석

이종태,김영란,김갑수,윤세의,박영민 대한상하수도학회 2003 상하수도학회지 Vol.17 No.2

When calculating the storm runoff from road surface, it is recommendable to introduce the critical duration of rainfall by means of the RUNOFF (SWMM) model, or the Rational method with the travel time values of the kinematic wave' or Kerby's equation modified by multiplying the correction factor of 2.3 or 1.1, respectively. But the travel time of 5-10 minutes suggested in the Guide Manual for Sewer Design is too long to use for calculating road surface runoff. The peak runoff rate increases as the road sectional slope increases, whereas it shows the opposite results for an increase in the longitudinal slope. Also, the effects of the width and length of the road on the surface runoff rates increases greatly, as their values increase.

《竹取物語》성립에 관한 일고찰

이영란 효성여자대학교 한국전통문화연구소 1996 韓國傳統文化硏究 Vol.11 No.-

『竹取物語』の內容の中で, 特に翁による主人公かぐや姬の發見の部分と, 後半部の月の世界への昇天を語る部分は, 『萬葉集』『風土記』『今昔物語集』その他に, 類似する話として傳ぇられている. これはすなわちこの物語の素材が全篇にわたって古代に傳ぇられていた多くの民間說話をはじめ, いろいろの多樣な傳承屑話に基づいているのを語っている. それで本考では, この物語の中核をなす素材が具體的にどんなものであるかを考察し, それが 作品の中ではどうふうに取り扱われているのかを調べることで, この物語の主題性について考えてみることにしたい. 『竹取物語』は 素材の面から見ると大きく羽衣傳承と難題求婚譚の二つの流れをなしているが, いずれにしろ古代傳承それ自體がそのまま作品に なったのではなく, 傳えられていろいろの素材を消化し, 創作されたものと認めなければならい要素が多いにある. つまり この作品は日本古代に傳えられていた民間素材をもとにして, それが羽衣傳承が創作のヒントとなり 作品の現實性を加える效果も出す實在人物名を使つた難題求始譚を混ぜて出來あがつた假名散文作品である.

康有爲의 敎育改革

이영란 조선대학교 전통문화연구소 1999 전통문화연구 Vol.6 No.-

특발성 과호산구 증후군 환자의 치료 도중 발생한 간혈종 1례

이영태,김동기,박지훈,김윤정,김기향,박보민,권민정,김애란,이원식,주영돈,손창학 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Idiopathic hypereosinophilic syndrome is characterized by marked elevation of eosinophil count ( >1,500/㎣) in peripheral blood without explaining etiology. It shows tissue involvement in many organs such as liver, G-I tract, myocar dium, lung, skin, kidney and nerve. Some case of hypereosinophilic syndrome with hepatic involvement have been reported, but not much. We have recently experienced a case with idiopathic hypereosinophilic syndrome of a 40 year old man who presented with RUQ pain. By abdominal CT, ill- defined subcapsular hematoma was detected. Liver biopsy showed eosinophilic infiltration within the portal tract and sinusoid. Drain procedure and corticosteroid adminiiatbrought marked improvement of clinical manifestation, hematologic abnormality and radiologic abnormality.

天孫降臨と聖婚物語

李永蘭 효성여자대학교 한국전통문화연구소 1995 韓國傳統文化硏究 Vol.10 No.-

始祖神이 山上에 來臨하는 神話의 유형은, 北方아시아 지역에 널리 분포되어 있는 것으로,『古事記』『日本書紀』의 내용을 중심으로 하는 일본신화에서도 예외는 아니다. 天上世界의 이야기가 주로 다루어지는 高天原系神話에서는, 天照大神에 의해 天孫이 「中ツ國」에 내려와 혼돈과 무질서 상태의 지상국을 다스리게 된다는 내용이 주를 이루고 있다. 본고에서는 天上世界에서 地上世界로 下降한 天孫이 즉위의식과 함께 곧이어 혼인의식이 갖추어지고 있는 것으로 전하여지는 부분을 들어서 그 점이 의미하는 바의 중요성을 인식하고자 한다. 日本神話의 구성에서 보이고 있는 天孫과 地上神의 딸 "木花之開耶姬"와의 혼인이 의미하는 바에 대하여, 종래의 민속적인 측면에서 연구한 부분, 그리고 제례의식적인 면에서 분석한 내용 등을 아울러 검토한 후, 본 논문에서는 이러한 시각과는 달리 이 부분을 규명해 보고자 한다. 古代帝王이 天神系 또는 天神을 아버지로 하고, 물의 女神을 어머니 또는 妃로 삼아, 天界水界 양쪽을 支配하는 靈能을 所有하고 있는 것으로 얘기되어지는 神話는 여러민족에게 전하고 있는 것으로, 그 形相에는 여러가지 다소 차이는 보이고 있으나, 근본 이면에 있어서는 공통하고 있는 것이다. 記紀神話 중에는 地方아시아적 요소 뿐 아니라, 南方 해양민 문화 요소도 많이 포함하고 있어, 高天原系 神話인 天孫의 강림을 서술한 부분은 다분히 前者의 내용을 다룬 것이며, 木花之開耶姬와의 혼인이야기 부분은 後者의 요소를 전하고 있는 것이다. 그것이 즉위 후 성혼이 있게 되고 그로서 왕권이 성립됨이 묘사 되어진 후, 점차 왕권의 성장과 더불어 왕권의식이 강화되어져 가게 된다. 더불어 木花之開耶姬와의 결혼부분에서 언급되는 天孫의 모습은 분명히 海上來訪型의 神의 性格을 띈 것으로 묘사되어지던 것이, 그 내용이 변화 되어져서, 天上에서 강림하는 天上神의 성격으로 바뀌어져 간 것으로 유추해 보는 바이다.

보건교사와 일반교사의 성교육 수업실태, 자료 활용도 및 문제해결 요구도 비교

이정란,안숙희,김영혜,조규영 韓國學校保健學會 2004 韓國學校保健學會誌 Vol.17 No.2

Purpose : This descriptive study was conducted to compare the teaching status, utilization of the teaching materials, and the need to solve matters of sex education between the school health educators and teachers working in an elementary school in Busan. Method : 182 school health educators and 125 teachers participated in the research. Data was collected using a self-administered questionnaire, and analyzed by frequency and x2 .test using the SPSS WIN 10.0 Program. Results: While school health educators carried out most of the sex education in the extra curriculum and physical education class, teachers did in the regular curriculum and physical education class. Regarding the utilization of the teaching materials on sex education, although the majority of school health educators used the teacher's manual, only a few teachers used it. Most of the school health educators used the ICT teaching materials while only half of the teachers did. Regarding the methods to solve matters on sex education, school health educators responded that a sex-related subject should be combined with a health subject, and an independent sex-related subject was necessary. The teachers, however, responded that it was necessary to secure enough time for sex education, the sex-related subject combined with a health subject was necessary, and there is a need to designate a sex educator. Conclusion: School health educators utilized more teaching materials for sex education and suggested more active methods to solve matters related to sex education. Therefore, school health educators should be more active as sex educators, and the subject of sex education should be adopted as a regular course.