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전용진,조석형,홍영호,한종필 호서대학교 반도체제조장비국산화연구센터 2001 반도체장비학술심포지움 Vol.2001 No.-
폴리카본산계 기능성 고분자를 합성해서 고성능 감수제 원료로 활용하여 고유동화 혼화제를 개발하고자 한다.폴리카본산계 기능성 고분자를 합성한 후, 이를 고유동, 고강도 혼화제 원료로의 제반 물성을 확인하고, 이를 현장에 적용하여 현재의 제품을 획기적으로 개선하고, 혼화제 품질의 우위성을 확보하기 위해 1)시멘트 및 골재 표면에서의 적절한 계면활성을 갖는 분자설계를 하였으며, 2)분자량의 조절 기술의개발를 개발하였다. 합성에 있어서 첫째, 시멘트 및 골재 표면에서의 적절한 계면활성을 갖는 분자설계와 둘째, Mw 5,000정도의 분자량을 갖는 감수제의 합성기술을 개발하였다.이렇게 제조된 고성능 유동화제의 화학구조 해석를 해석하고 분자량 및 분자량 분포를 측정한 다음, 시멘트 페이스트의 유동성, 점도, 슬럼프로스 등을 측정하여 고성능 유동화제의 성능인 시멘트 페이스트의 유동성을 시험하였다.그 결과 고유동성을 갖는 것과 장시간 안정한 유동성을 나타내었으며, 경과 시간에 따른 겉보기 점도변화를 측정한 결과 점도의 상승이 초기에 일어나다가 시간의 경과에 따라 점도가 감소하는 경향을 나타내었다.따라서 경과시간에 따른 유동성손실을 억제할 것으로 기대한다.
Oh, Phil Yong,Kim, Jung Hyun,Hong, Youngjune,Cho, Seok Ho,Cho, Guangsup,Choi, Eun Ha IEEE 2008 IEEE transactions on plasma science Vol.36 No.3
<P> In this paper, spatiotemporal behavior of the excited Xe-atom density of <TEX> <TEX>$1{\rm s}_{5}$</TEX></TEX> metastable state was investigated by laser-absorption spectroscopy in alternating-current plasma display panel in accordance with the Xe mole fraction to Ne, which can be connected to the relative luminous efficiency over all spaces in a discharge cell. The various test panels with Xe mole fractions of 4%, 7%, 10%, and 15% to Ne have been used in this paper, in which discharge cell with T-typed indium–tin–oxide electrode and closed-barrier rib has been adopted. In this paper, the density of metastable state for the excited Xe atom is found to increase slowly beyond the Xe mole fraction of 10%. It is also accordingly noted that the luminous efficiency increases slowly beyond the Xe mole fraction of 10%, which is similar to that of the density of the excited Xe atoms in the metastable state in this paper. </P>
제주흑우, 한우 및 수입 소 품종에서 새로운 indel 마커의 다형성과 대립인자 분포
한상현(Sang-Hyun Han),김재환(Jae-Hwan Kim),조인철(In-Cheol Cho),조상래(Sang-Rae Cho),조원모(Won-Mo Cho),김상금(Sang-Geum Kim),김유경(Yoo-Kyung Kim),강용준(Yong-Jun Kang),박용상(Yong-Sang Park),김영훈(Young-Hoon Kim),박세필(Se-Phil Pa 한국생명과학회 2012 생명과학회지 Vol.22 No.12
본 연구는 소 유전자 database들에 대한 사전 비교연구에서 발견된 삽입/결실(indel) marker들의 다형성과 각각의 유전자형의 분포를 확인하고자 수행하였다. 먼저, 소의 유전체 서열과 발현서열표식(EST) database 간의 생물정보학적 비교를 통해 전체 51 종의 indel marker들을 검출하였다. 이 중에서 42 종을 평가하여 최종적으로 9 종의 정보력이 있는 marker들을 집단분석을 위해 선발하였다. 각각의 marker들에 대한 염기서열을 재분석하였으며, marker의 다형성을 한국 재래소 품종인 한우와 제주흑우(JBC), Holstein, Angus, Charolais, Hereford 등 6 품종에서 조사하였다. 본 연구에서 이용한 소 6 품종은 8 종의 marker들에 대해 다형성을 나타내었으나, Indel_15의 경우 Holstein과 Charolais에서 다형성이 발견되지 않았다. JBC 집단에 대한 분석에서는 관찰된 이형 접합자 빈도는 HW_G1 (0.600)에서 가장 높고, Indel_29 (0.274)에서 가장 낮았다. Marker에 대한 다형정보량의 수준은 HW_G4 (0.373)에서 가장 높고, Indel_6 (0.305)에서 가장 낮은 수준을 보였다. 본 연구에서 조사한 새로운 indel marker들은 특히 제주흑우 집단의 생산성 향상을 위한 분자육종 체계의 개발뿐만 아니라 친자확인이나 생산이력추적을 위한 유전정보를 제공하는데 유용할 것으로 기대된다. The aim of this study was to screen the polymorphisms and distribution of each genotype of insertion/deletion (indel) markers which were found in a preliminary comparative study of bovine genomic sequence databases. Comparative bioinformatic analyses were first performed between the nucleotide sequences of Bovine Genome Project and those of xpressed sequence tag (EST) database, and a total of fifty-one species of indel markers were screened. Of these, forty-two indel markers were evaluated, and nine informative indel markers were ultimately selected for population analysis. Nucleotide sequences of each marker were re-sequenced and their polymorphic patterns were typed in six cattle breeds: Holstein, Angus, Charolais, Hereford, and two Korean native cattle breeds (Hanwoo and Jeju Black cattle). Cattle breeds tested in this study showed polymorphic patterns in eight indel markers but not in the Indel-15 marker in Charolais and Holstein. The results of analysis for Jeju Black cattle (JBC) population indicated an observed heterozygosity (Ho) that was highest in HW_G1 (0.600) and the lowest in Indel_29 (0.274). The PIC value was the highest in HW_G4 (0.373) and lowest in Indel_6 (0.305). These polymorphic indel markers will be useful in supplying genetic information for parentage tests and traceability and to develop a molecular breeding system for improvement of animal production in cattle breeds as well as in the JBC population.
Phil Kyu Lee,Jae Lim Chung,Da Ran Kim,Young Chae Yoon,SoonWon Yang,Woong-Joo Whang,Yong-Soo Byun,HyungBin Hwang,Kyung Sun Na,HyunSoo Lee,So Hyang Chung,Eun Chul Kim,YangKyung Cho,Hyun Seung Kim,Ho Sik 대한안과학회 2024 Korean Journal of Ophthalmology Vol.38 No.1
Purpose: In the present study, we determined the prevalence of obstructive meibomian gland dysfunction (MGD), hyposecretory MGD, grossly normal MG, and hypersecretory MGD in patients with dry eye syndrome using lipid layer thickness (LLT) and MG dropout. Methods: Eighty-eight patients with dry eye syndrome were included in the study. Patients were categorized into four groups according to the LLT and weighted total meiboscore. The proportion of patients in each group was calculated. The age, sex, Ocular Surface Disease Index, LLT, Schirmer, tear film breakup time, cornea stain, weighted total meiboscore, expressibility, and quality of meibum were compared between the four groups. Results: Fifteen eyes (17.0%) had obstructive MGD, two eyes (2.3%) had hyposecretory MGD, 40 eyes (45.5%) had grossly normal MG, and 17 eyes (19.3%) had hypersecretory MGD. The obstructive MGD group was younger than the grossly normal MG group. In obstructive MGD, the ratio of men to women was higher than that of the other groups. However, Ocular Surface Disease Index, Schirmer, tear film breakup time, and corneal stain did not show statistically significant differences between the four groups. The meibum expressibility of the hyposecretoy MGD group was worse than those of the other groups. The meibum expressibility of the hyposecretoy MGD group was poor than those of the obstructive and hypersecretory MGD group. Conclusions: This categorization was expected to help determine the best treatment method for dry eye syndrome, according to the MG status.
Indirect Reduction Technique in Proximal Humeral Fractures Stabilized by Locking Plates
Yong Girl Rhee,Nam Su Cho,Sang Won Cha,Seong Cheol Moon,Sang Phil Hwang 대한견주관절의학회 2014 대한견주관절학회지 Vol.17 No.1
Background: Indirect reduction technique offers a valid option in the treatment of proximal humerus fracture. The purpose of this study is to evaluate the functional outcome and the complication rate after indirect reduction and internal fixation of unstable proximal humeral fractures with use of a locking plate. Methods: Twenty four patients with acute proximal humerus fracture were managed with indirect reduction and internal fixation with a locking plate. The mean follow-up period was 15.5 months. Results: The anatomical reduction of the medial cortex buttress was seen in 16 patients (66%) of the Group A and the non-anatomical reduction was seen in 8 patients (33%) of the Group B. Mean union time was 3.2 ± 1.9 months; it was 2.2 ± 0.6 months in the Group A and 5.3 ± 2.2 months in the Group B (p < 0.05). In our series, there were 6 cases of complications and these include 2 cases of varus malunion, 2 cases of shoulder stiffness, 1 case of heterotrophic ossification, 2 cases of screw perforation and 1 case of impingement. Conclusions: We conclude from our studies that indirect reduction and internal fixation using locking plate for acute proximal humerus fracture can give good results with bony union and predictable good overall functional outcome. If the medial cortex buttress is well maintained, a better anatomical reduction would be achieved, the union would be prompted, the pain would be further reduced and the range of the motion would be recovered more promptly.
A Case of Cutaneous Angiomyolipoma
조광현,Kye Yong Song,문상은,안필수,이용숙 대한피부과학회 1996 Annals of Dermatology Vol.8 No.1
We describe a case of cutaneous angiomyolipoma found in the ear lobe, that is not associated with tuberous sclerosis. The lesion developed on the youngest patient yet reported in the literature.
정필현,강석,채동주,조윤철,김태영,홍정용 東國大學校醫學硏究所 1997 東國醫學 Vol.4 No.-
전이성 골종양은 악성 골종양중 발생빈도가 가장 흔한 것으로 알려져 있으며 다발성 전이가 빈번하고 심한 통증 및 병적골절을 유발하게 된다. 골격으로 전이되는 암의 원발병소로는 유방암, 전립선암, 폐암, 갑상선암, 신장암이 전체의 80%이상을 차지하며 전이부위는 적색골수가 존재하는 곳에 호발하는데 주로 척추, 늑골, 골반골, 장광골의 근위 말단부, 흉골, 두개골의 순서로 빈도가 증가한다고 한다. 전이성 골종양은 대부분 구간골격에서 발견되며 사지골격으로의 전이는 흔치 않은 것으로 알려져 있으며, 특히 수부, 족부로의 전이는 매우 드문 것으로 보고되어 있다. 본 정형외과학 교실에서는 편평 상피세포암종을 가진 환자에서 발견된 좌측 종골의 전이성 골종양 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Metastatic lesions of bone are more common than primary malignant tumors, are usually multiple, and compromise the patient's health by causing intense pain, interfering with surrounding neural or muscular structures, causing pathological fractures. More than 80% of cancers that spread to bone are those of the breast, protate, lung, thyroid gland and kidney. The sites of metastasis are predominantly in red bone marrow. The metastatic foci are commomly centally distributed. The spine is most commonly involved, followed by the rib, pelvis, proximal ends of long bones, sternum and skull. The peripheral bone involvement is rare. Particularly, metastases to the bones of the hand and feet are extremely rare. The authors present a case of metastatic bone tumor of the calcaneus from squamous cell carcinoma of the lung with clinical details.