지속성 외래복막투석 환자들의 예후에 영향을 미치는 요인들에 관한 고찰

권혁만,김찬덕,조지형,장민화,최혁준,이현철,박자용,박선희,김용림 대한신장학회 2004 대한신장학회잡지 Vol.23 No.2

음향 방출을 이용한 저어널 베어링의 조기 파손 감지(Ⅲ) - 저어널 베어링 AE 진단 시스템 개발

조용상,권오양,정민화,윤동진 韓國非破壞檢査學會 1996 한국비파괴검사학회지 Vol.16 No.3

회전 기계의 저어널 베어링 상태를 음향 방출(AE) 기술을 활용하여 감시하기 위한 진단 시스템을 개발하였다. AE 기술은 베어링 시스템에 있어서 비정상 상태를 탐지하기 위하여 이용된다. 모의 저어널 베어링 시스템을 이용한 실험과 실제 발전 설비에 대한 적용 시험의 결과로부터 AE 신호 파라메타 중에서 rms voltage가 가장 유효한 것으로 판명되었으며, 이러한 연구 결과를 토대로 하여 진단 시스템의 알고리즘과 판단 기준들이 설정되었다. 베어링 진단 시스템은 AE 센서 및 전치앰프로 구성된 신호 감지부, AE rms voltage를 측정하기 위한 rms-to-DC 변환 회로부로 구성된 신호 처리부, A/D 변환기를 이용하여 rms voltage 신호를 PC에 연결해 주는 인터페이스부, 베어링 상태 보기와 진단 프로그램을 포함하는 그래픽 디스플레이 및 소프트웨어부의 4부분으로 구성된다. For the condition monitoring of the journal bearing in rotating machinery, a system for their diagnosis by acoustic emission(AE) was developed. AE has been used to detect abnormal conditions in the bearing system. It was found from the field application study as well as the laboratory experiment using a simulated journal bearing system that AE RMS voltage was the most efficient parameter for the purpose of current study. Based on the above results, algorithms and judgement criteria for the diagnosis system was established. The system is composed of four parts as follows: the sensing part including AE sensor and preamplifier, the signal processing part for RMS-to-DC conversion to measure AE rms voltage, the interface part for transferring RMS voltage data into PC using A/D converter, and the software part including the graphic display of bearing condition and the diagnosis program.

벼의 잎 ·목 稻熱病에 대한 抵抗性의 比較

權寧閑,鄭厚燮,趙鏞涉,朴恩雨 서울大學校 農科大學 1986 서울대농학연구지 Vol.11 No.1

1. Differences in reactions of leaf and neck of rice plants to rice blast among four rice cultivars were observed in a paddy field. Cultivars Jinheung and Milyang 23 showed susceptible and resistant reactions, respectively, on both leaf and neck. Cultivar Norin 6 was susceptible to leaf blast and became intermediately resistant to neck blast whereas cultivar Ginga showed resistant and intermediately resistant reactions on leaf and neck, respectively. 2. Three different heading dates at 5 to 8 day intervals were induced by transplanting seedlings of four cultivars from seedling beds to a paddy field three times at 9 to 10 day intervals. When blast severity was compared within cultivars, leaf blast severity increased as heading dates became late. However, neck blast severity was greater in plots with early heading dates than those with late heading dates. 3. Spore germination of two isolates of Pyricularia oryzae in tissue extracts from leaf and neck of four rice cultivars indicated significant interactions between cultivars and isolates. However, spore germinations in leaf and neck extracts were not significantly different. Mean degree of hyphal growth of four P. oryzae isolates on the sheath adaxial epidermis indicated significant interactions between cultivars and isolates. 4. Some anatomical characteristics of leaf and neck of four cultivars did not have apparent relationship with the reactions of four cultivars to rice blast in the paddy field. Also, the amounts of the total nitrogen, sugar, P₂O??, and SiO in flag leaf and neck were not significantly different among four cultivars and did not seem to affect changes in reactions of cultivars Norin 6 and Ginga to leaf and neck blasts observed in the paddy field.

크레인의 능력을 고려한 MOB 자동창고 시스템의 저장과 불출정책

조용환,손권익 江原大學校 産業技術硏究所 1996 産業技術硏究 Vol.16 No.-

This paper deals with storage and retrieval policies for S/R machine with capacity constraints in Man-On-Board AS/RS. It is assumed that storage sequence is based in SFC(spacefilling curve) routine and that storage layout is dedicated by storage policies. We present several heuristic algorithms for storage and retrieval policies which minimize total distance travelled by the S/R machine. These algorithms are based on COI.group COI, frequency of order, similarity between items and capacity of S/R machine. Experimental results of 24 combinastorial policies are provided to illustrate the performance of the heuristics under various rack utilization ratio. In storage policies, the results show that algorithms considering both similarity and frequency are better than those with COI as rack utilization is increasing. And algorithm using group COI is superior to others. In retrieval policies, the method with revision expression is shown to be better than others.

단백뇨를 보이는 사구체 질환 및 당뇨병성 신병증에서의 Lp(a)

권태환,김준홍,조성,김석재,김용림,조동규,백미영 경북대학교 병원 1998 경북대학교병원의학연구소논문집 Vol.2 No.1

Background: Recently there has been evidences that serum Lp(a), an independent risk factor to atherosclerotic cardiovascular diseases, were increased in proteinuric disorders such as nephrotic syndrome and diabetic nephropathy. Methods: We intended to search of altered concentrations of Lp(a) in proteinuric disorder measuring serum Lp(a) concentrations with ELISA in 44 glomerulonephritic patients(25 nephrotic syndrome(NS), 19 non-nephrotic range proteinuric glomerulonephritis(GN), 25 diabetic nephropathy patients(DN), and 31 healthy controls(HC). Also, we compared Lp(a) concentration between glomerulonephritis patients and diabetic nephropathy patients with proteinuria of similar degree. Results: 1) There were significantly increased levels of total choesterol, triglyceride, and LDL-cholesterol in Ns compared to GN, DN, HC. 2) There were significantly increased concentrations of serum Lp(a) in NS compared to HC, but no signiicant difference in serum Lp(a) among NS, GN, and DN. 3) There was no significant difference in serum Lp(a) concentrations between NS & DN with 24 hour urine protein greater than 3.0g. 4) There was no significant difference in serum Lp(a) concentration between GN with 24 hour urine protein greater than 0.5g and less than 1.5g and DN with proteinuria of simial degree. 5) In glomerulonephritis patients, there was negative correlation between serum Lp(a) concentration and serum albumin level but correlation with 24 hour urinary protein, total cholesterol, Ldl-cholesterol, and HDL-cholesterol was not shown. In diabetic nephropathy, there was no significant correlation among serum Lp(a) concentration and all parameters including serum albumin, 24 hour urinary protein, and other lipid profiles. Conclusion: The present study confirmed that patients with nephrotic syndrome of diverse etiologies have makedly increased plasma level of Lp(a), in conjunction with other lipid abnormalities. However, this study shows no difference in Lp(a) concentrations between diabetic nephropathy and glomerulonephritis with similar degree of proteinuria.

의치상 재이장재의 물리학적 성질에 관한 연구

권용원,조인호 단국대학교 치의학연구소 1990 논문집 Vol.2 No.-

The purpose of this study was to compare the fitness, hardness and bending strength of the conventional reliners and visible light curing reliner. Nine regions were selected in the upper transverse section which were thought to be of interest from a clinical standpoint and the discrepancies between the dentures and the master cast in these regions were determined by the coordinated measuring machine (UMM-500, Zeiss, W. Germany). The results were as follows: 1. The experimental denture bases showed the lowest fitness at the central portion of the posterior palatal border and the intimate contact in the buccal flanges regardlness of relining materials and relining methods. 2. The fitness of relined denture base was the best in autopolymerizing group and in the order of long processing, short processing and visible light curing group. 3. The fitness after 24 hour-storage in water was improved in long processing and autopolymerizing groups, but there was no significant difference. 4. The hardness was the highest in long processing group and decreased in the order of short processing, visible light curing and autopolymerizing group. 5. The bending strength was the highest in long processing group and decreased short processing, visible light curing, and autopolymerizing group in order.

기본 항암 화학요법에 불응 하는 전이성 이행상피 세포암 환자에서 시행한 증량 M-VAC 항암 화학 요법 2례

조용현,권병산,이지열,김세웅,이충범,윤문수 대한화학요법학회 1997 대한화학요법학회지 Vol.15 No.3

1. 목적 전이성 방광 이행 상피 세포암의 경우에 시행될 수 있는 몇가지 전신적 항암 요법 중 M-VAC 병용 투여가 가장 인정받고 있는 항암 요법이긴 하나 일시적 반응 후 재발시 즉 M-VAC 병용투여에 불응하는 경우 증상 완화 요법(palliative therapy) 이외에 다른 치료 방법이 없었다. 저자들은 M-VAC 병용 요법에 불응하는 전이성 방광 이행상피 세포암 환자 2례에서 기존 M-VAC 항암 화학 요법보다 항암제 투여량을 증량한 M-VAC 항암 요법을 시행하였다. 2. 방법 기존 M-VAC 항암 화학요법용량(Methotrexate 30㎎/㎡, Vinblastine 3㎎/㎡, Adriamysin 30㎎/㎡, Cisplatin 70㎎/㎡)보다 항암제 용량을 증량하고(Methotrexate 30㎎/㎡, Vinblastine 4㎎/㎡, Adriamycin 60㎎/㎡, Cisplatin 100㎎/㎡) 이로 인한 골수 저하증을 예방하기 위하여 GM-CSF를 동시에 투여하였다. 3. 결과 증례 1 환자는 중량 항암 화학 요법 1개월 후 추적검사에서 전이된 임파절이 모두 소실된 완전 관해를 보였으며 증례 2 환자는 증량 항암 요법 후 14일째 폐혈증으로 사망하였다. 4. 결론 증량 M-VAC 항암 화학 요법은 아직 시행 기간 및 증례가 많지 않아 완전 관해 기간 및 적절한 항암요법 시행 횟수의 미확립, 항암제 치료 도중의 치사율의 감소등이 문제점으로 지적되고 있으나 기존 M-VAC 항암 요법에 불응하는 전이성 방광이행 상피 세포암 환자에서 우선 고려될 수 있는 치료법으로 사료된다. Background : M-VAC(methotrexate, vinblastine. doxorclbicin, cisplatin) chemotherapy is the most common and effective treatment modality for advanced transitional bladder tumor. However, there is no effective therapy in case of the patients nith bladder tumor refractory to M-VAC chemotherapy. Methods : Two male patients mith metastatic transitional bladder tumors refractory to conventional chemotherapy with methbtrexate, vinblastine, doxorubicim, and cispiatin (M-VAC) were treated with escalate3 dose of M-VAC plus recombinant human granulocyte-macrophage colony stimulating factor (rhGM-CSF). Formula of escalated M-VAC chemotherapy were 30mg/m^(2) of inethotrexate, 4mg/m^(2) of vinblastine. 60rmg/m^(2) of doxorubicm, and 10Omg/m^(2) of cisplatin, and 250mg/m^(2) rhGM-CSF per day administered subcutaneously (SC) for 10 consecutive days. Result : One of the treated patients mas responded with complete remission and the other one m-as dead by sepsis on post-escalated M-VAC chenctherapy 14 days. Coclusion : We believe escalated M-VAC chemotherapy may be one of the effective alternative treatment for patients with metastatic urothelial tumor refractory to conventional M-VAC chemotherapy.

복합열화환경하에서의 중성화 및 염화물이온 확산특성이 철근부식에 미치는 영향에 관한 실험적 연구

조봉석,장재봉,김재환,김용로,권영진,김무한 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

It is recognized that reinforcement corrosion is the main distress behind the present concern regarding concrete durability. In this study, to confirm corrosion of reinforced concrete due to permeability of carbonation and chloride ion affected by thickness of cover, kinds of surface coating, measured electric potential, ratio of corrosion area, weight reduction, corrosion velocity of steel bar under environment of complex deterioration. The results showed that an increase in age also decreases Carbonation velocity coefficients and increases Chloride ion diffusion coefficients. As well, an increase in age also increases corrosion of reinforcement due to permeability of carbonation and chloride ion. Corrosion of reinforcement by thickness of cover is superior to 10mm thick than 20mm thick. It showed that an increase in thickness of cover prevent steel bar from deteriorating due to permeability of carbonation and chloride ion. The results of this study showed that corrosion velocity was affected by thickness of cover, kinds of surface coating. data on the development of corrosion velocity made with none, organic B, organic A, inorganic B. and inorganic A is shown.

複素 雙人力 記述函數를 이용한 制御系의 應答速度 補償에 관한 硏究

권세현,조용갑,박양수,최부귀 東亞大學校 附設 情報通信硏究所 1995 情報通信硏究所論文誌 Vol.3 No.1

The technique for the synthesis of the dual-input describing function(DIDF) is introduced here and the construction of a non-linear electronic compensator(N-L-E-C) based on this technique is proposed. The above non-linear network is used to compensate linear and non-linear systems for instability,speed of response, limit cycle and the static accuracy.

악교정 환자의 악교정 수술전후 발음양상에 대한 비교연구

권경환,김수남,이동근,조용민,이숙향 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.2

The purpose of this study was undertaken to determine the effects of orthognathic surgery on speech. The hyposis stated herein is that functional behaviors of the dentofacial complex, such as speech production, may be adversely affected by deviations of a structural nature(especially, Class III malocclusion) . Twenty adults with Class III malocclusion(13 female and 7 male) were studied preoperative, immediate postoperative and either 6 or 12 months postoperative lateral cephalograms. They had mandibular prognathism and had undergone mandible setback operation. The position of tongue, soft palate(Uvula), hyoid bone, respiratory track width, and pharyngeal depth were assessed on lateral cephalograms with 23 cephalometric variables, ANOVA, Paired t-tests and Pearson's product-moment correlation coefficient tests were used to evalute the operative changes in all cephalometric parameters. A experienced speech and language pathologists performed narrow phonetic transcriptions of tape-recorded words and sentences produced by each of the ninth patients and the recording tapes were analyzed by phonetic computer program(Computerized Speech Lab(CSL) Model 4300BI(U.S.A.)) These judges also recorded their ratings of each patient's overall consonants, hypernasality, hyponasality, and articulation proficiency. The results obtained are as follows ; 1.There were significant changes in distance of posterior pharyngeal wall to tongue (TI-TW2, TS-TW3) after the surgery at 6 months postoperatively(each p<0.01 p<0.05) 2.The posterior tongue point(TI, TS, PPT) moved posteriorly after surgery and remained to its changed position at 6 months postoperatively(p<0.05) . The displacement of tongue was correlated with the movement of mandibular setback amount(p<0.05). The hyoid bone moved posteriorly superiorly after immediate postoperative period. There was significant changes in hyoid bone movement after immediated post-operative period(p<0.05), but returned to its original position during the follow-up period(p>0.05) 3.The soft palate was displaced posteriorly superiorly after immediated operative period and remained to its changed position at 6 months postoperatively(p<0.05) ANS-PNS-SPT angle increasing, PPU-PPPo distance narrowing was showed after surgery, and remained its appearance 6 months postoperactively (p<0.05) 4.There were significant changes in formant value and squre diagram of vowel sound after the orthognathic surgery and the follow-up period. There were significant changes in /ㅅ/sound and posterior tongue sound. 5.The posterior movement of tongue and the posteriosuperior movement of soft palate was correlated with mandibular setback amount after orthognathic surgery. On the vowel squre diagram, the author found that the place of articulation after operation moved downward, backward, upward. 6.In assessing speech abnormalities, dental occlusion should be considered as a contributing factor. The vast majority of subjects with preoperactive misarticulations eliminated or reduced their errors following orthognathic surgery. There was significant difference in speech impovement between pre- and post-operation.