신경섬유종증 환자에서 상완신경총 병변의 소견을 보인 척추 신경섬유종

양충용,박효인,박순아,박종태,정선관,신용일 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.2

본 증례는 50세 여성의 제 1형 신경섬유종 환자로서 척추 신경섬유종에 의해 초기 상완신경총 병변 소견을 보였다. 약 4개월 동안 후경부통, 좌측 견관절, 좌측 상완의 마비를 보였으며, 초기 전기진단학적 검사상 경수 5번과 6번 신경근을 중심으로 쇄골상부 신경절전성 상완신경총 병변이 관찰되었다. 그러나, 액와 자기공명영상, 초음파검사, 단순 방사선검사, 골주사 등의 영상학적 검사에서는 심한 흉추 척추 전-측만증과 경수 뇌경막에 확장 소견을 제외하고는 상완신경총 병변의 소견은 관찰되지 않았다. 7개월경과 후, 좌측 상지 및 양측 하지의 근력 저하, 경수 4번이하의 감각 저하, 경도의 흉통을 동반한 호흡곤란이 진행되었다. 응급으로 시행된 경수 자기공명영상에서 좌측 경수 3번과 4번에 경막내 액와-속질의 신경종양이 진단되었다. 수술적 처치를 시행하였으며, 거시적 관찰상 척수 신경섬유종이 진단되었다. 급격히 진행하는 척수 신경섬유종은 초기에 상완신경총의 신경근 병변의 소견을 보일 수 있으므로, 신경섬유종증 환자에서 상완신경총 병변의 진단에 세심한 주의를 요한다. We observed a patient with symptom similar to brachial plexus lesion caused by spinal neurofibroma in a 50-year-old female with a history of neurofibromatosis-1(NF-1). She presented with posterior neck, left shoulder and left upper arm paralysis of 4 months duration. The initial electrodiagnostic study(EDS) revealed supraclavicular preganglionic brachial plexus lesion of mainly involved left C5 and C6 roots. However, radiological imagings including axillar MRI, ultrasonography, cervical plain radiography and bone scintigraphy showed no definitive brachial plexus disease except cervical dural dilation and severe thoracic scolio-Iordosis. On 7 months after the first admission, she had aggravated muscle weakness on the left upper arm and both lower extremities, sensory impairment below C4 and respiration difficulty with the chest pain. Emergency MRI showed intradural axillar-medullary neurogenic tumor at the left C3-C4. Subsequently, the patient was treated with surgical resection. Grossly specimen examination displayed the presence of a spinal neurofibroma. In rapidly progressing spinal neurofibroma represented firstly as root lesion of brachial plexus in EDS, the physician should pay scrupulous care to evaluate the cause.

경주지역 여고생의 초경과 체성장간의 관계

김준섭,권오구,박진석,오종수,박정현,박제식,안세한,이용환,서정호,신태섭,최영배,김덕수,이관,박수경 東國大學校醫學硏究所 2002 東國醫學 Vol.9 No.1

본 연구는 경주지역 1개 고등학교 3학년 여고생을 대상으로 초경 시작 전인 초등학교 4학년부터 고등학교 2학년까지의 키, 몸무게, 가슴둘레 수치와 초경 연령을 파악하여 여성의 초경이 빠를수록 체성장 속도의 변화가 있을 것이라는 가설을 기초로 두 요인간의 관련성을 파악하고자 시행되었다. 경주시 1개 여자고등학교 3학년생 총 317명에 대해 ㅊ경 나이, 초경시 심리 상태, 초경이 시작되었을 때의 상담 여부와 상담하였던 사람, 부모 신장과 초경전후의 식사 규칙성, 다이어트 경험, 수면시간, 스트레스, 음주/흡연 여부, 질병력 등에 대한 설문 조사를 시행하였고, 초등학교 4학년부터 고등학교 2학년까지의 키, 몸무게, 가슴둘레에 대한 정보는 건강기록부에서 확보하였다. 상기 대상자 중 건강기록부가 분실된 39명, 초경나이에 대해 응답하지 않았던 29명 및 결석 등으로 조사를 하지 못하였던 42명을 제외한 조사 대상자는 206명으로 선정하였다. 대상자들의 초경연령 평균값(Mean±SD)은 13.0±1.11이었고, 초등학교 4학년부터 고등학교 2학년까지의 초경 이후 신장 성장률은 감소하였으며, 초경연령이 빠른 군이 초등학교 때는 신장에 있어서 우위를 차지하나 고등학교에 오면서 신장은 비슷한 수준이 되었다. 초경후 1-2년 사이에 체중과 흉위의 증가율은 감소하였고, 초경연령이 빠른 군이 초등학교와 고등학교 사이에 체중과 흉위에서 모두 우위를 차지하였다. 본 연구의 결과는, 흔히 이차 성징의 시작 시점 혹은 사춘기의 시작 시점으로 보고있는 초경 연령이 청소년기의 성장과 밀접한 관련성이 있고, 특히 체중과 흉위의 성장 속도와 밀접한 관련성이 있음을 시사한다. To understand the onset of menarche in relation to changes in physical growth that take place during female adolescence, especially the changes in height and weight velocity. The 207 senior in one women high school of Kyongju were investigated in April 3 to 8, 2001. We collected the information, relation in the age at menarche, height & weight of parents, regularity of eating, and obesity diet, duration of sleeping, sickness & stress near age at menarche, by self-recording. The status of height, weight & chest circumference between the 4th grade of primary school and the junior of high school was collected by individual Health Record. The results were followed; The average age at menarche was 12.95±1.11 years old and the most frequent age of menarche is 13 years. After menarche, the velocity of height, weight and chest circumference were decreased. The most rapid group of menarche hold dominant position in height during elementary school. As time passed, they dont hold dominant position in height. The most rapid group of menarche get an advantage in the weight and the girth of chest after elementary school. The height of subjects is directly proportional to the height of their parents. These results suggest that the starting age at menestuation can be closely associated with physical growth and development.

설인신경 절단이 성곽유두 미뢰에 미치는 영향

박병건,노용관,차경,김재곤,백병주 大韓小兒齒科學會 1997 大韓小兒齒科學會誌 Vol.24 No.3

The effect of glossopharyngeal nerve transection on the taste buds of the rat vallate papilla was examined by using the method of DNA nick-end labeling (TUNEL) and standard electron microscopic technique at 1,3,5,7,9 days after denervation. In general, the number and size of taste buds decreased as more days passed after denervation. They started decreasing on day 3 post denervation. In studies using TUNEL method, TUNEL postive cells markedly increased in their numbers one day post denervation, as compared with controls. The number of apoptotic taste bud cells per taste bud profile was averaged to be 0.64 and 0.44 for day 1 and 3 post denervation, respectively, whereas it was 0.10 in controls. In electron microscopy, apoptotic cells were identified by the presence of condensed and fragmentary nuclei in a cytoplasm, which resulted in increased density. In control rats, only few apoptotic cells were found. On days 1 and 3 post denervation, nerve fibers almost disappeared from the taste buds and some apoptotic cells were apparent. On days 7 and 9 post denervation, a few taste bud cells were still present in the epithelium of the bottom of the trench wall of the vallate papilla and most of them showed apoptotic changes. The results indicate that the death of taste bud cells in normal conditions is controlled by apoptosis and the decrease and disappearance of taste buds sfter denervation is also caused by apoptosis of taste bud cells.

브러시레스 DC 모타의 最大起動 토오크를 위한 Hall Effect Sensor와 스테이터 코아 間의 最適配置

權鏞寬,兪榮植,李尙燁 成均館大學校 科學技術硏究所 1992 論文集 Vol.43 No.2

This paper describes how to arrange a hall effect sensor of brushless DC motor for the maximum starting torque and low torque ripple. To decide the optimal positioning of a hall effect sensor, the effect of time constant and hysteresis on hall effect sensor is considered. The 66° (E) is calculated as the optimal positioning between a hall effect sensor and a stator core for the maximum starting torque. But 68° (E) is demonstrated as the real positioning for the maximum starting torque through the test.

에폭시 수지 복합재료의 트래킹열화에 미치는 충전제와 자외선의 영향

박용관,조한구,김희곤 成均館大學校 科學技術硏究所 1994 論文集 Vol.45 No.1

This paper studies on the effect of ultraviolet light and filler on the tracking characteristics of epoxy resin which is widely used to enhance the insulation capability of materials. The specimens employed in the study were bisphenol and cycloaliphatic epoxy resins filled with Si0_2. A low-pressure mercury lamp was used as the source of UV light. In order to see the phenomena of tracking of the specimen, the expoerimentation is performed to the tracking apparatus(IEC, Publication 587) which mainly used under severe ambient conditions.

아질산 노출이 이스라엘잉어 혈장내 아질산 농도 및 간장 약물대사효소에 미치는 영향

박관하,최상훈,김영길,김용호,최선남,김종배 한국환경독성학회 2003 환경독성보건학회지 Vol.18 No.2

Effects of ambient nitrite, N0₂^(-), at 1, 3, 10 and 30 mg/l, on the changes of plasma nitrite/nitrate and on hepatic drug-metabolizing enzyme activity were examined in the juvenile Israeli carp, Cyprinus carpio. When the fish were exposed to 1 and 3 mg/l N0₂^(-), there was an exposure duration-dependent increase in plasma N0₂- over the 96-hr period reaching 6~7 fold excess the ambient concentration, In the fish exposed to 10 mg/l, a plateau concentration of less than 2-fold of the environment was attained in 12 hr. With 30 mg/l, however, the maximal plasma NOf was 41.25 mg/1 at 12 hr followed by a gradual decline. There was a concentration increase in methemoglobin (metHb) level in all N02^(-)-exposed groups and a significant decrease in hematocrit value in 30 mg/l group after 96-hr exposure. Apart from the blunted increase in plasma N0₂^(-) with higher N0₂^(-)(10 and 30 mg/1) exposure, the ratio of plasma N0₃^(-) to N0₂^(-) was significantly higher in these groups compared to 1 and 3 mg/l. The imbalance in the plasma N0₃^(-)/N0₂^(-) at higher N0₂^(-) exposure suggests a possible accelerated conversion of N0₂^(-) to N0₃^(-). Nitrite exposure did not affect the hepatic drug-metabolic activities in juvenile Israeli carp. All these data indicate that disposition of N0₂- differ depending upon exposed concentration and that metHb production may not be the exclusive toxic mechanism in carp

실린더형 압전소자 광지연선을 이용한 광 간섭형 단층촬영 시스템 제작

박성진,김영관,김용평 경희대학교 레이저공학연구소 2004 레이저공학 Vol.15 No.-

We demonstrate a compact Optical Coherence Tomography(OCT) system based on the optical fiber delay line controlled by a cylindrical Piezo-electric Transducer(PZT). The OCT system shows excellent characteristics for 2-dimensional imaging, exhibiting 96.90 of signal-to-noise ratio(SNR), 18.6±0.5㎛ of axial resolution, and l0㎛ of lateral resolution with an onion sample.

漏電遮斷方式에서의 漏洩靜電容量의 設定値에 관한 硏究

朴鏞寬,金恩培 成均館大學校 科學技術硏究所 1987 論文集 Vol.38 No.1

This paper deals with the ground fault protection from the leakage current in the low voltage distribution system. The protection was carried out mainly by ground connections of stern and loads. But in recent, with the increase of the voltage of the distribution system, it beings to introduce the ground fault current breakers, in this case the leakage capacitance of the distribution system is an important factor, and the range of proper values of the capacitance is determined by theoretical bases. Using this values, the limit value of the leakage capacitance for the proper operation range of earth leakage current breakers can he determined. The protection can be effectively applied and the reliability is improved in case of ground fault in the low voltage distribution system.

紫外線照射 複合에폭시樹脂의 劣化와 絶緣破壞

朴鏞寬 成均館大學校 科學技術硏究所 1990 論文集 Vol.41 No.1

This paper studied the effect of ultra-violet light on the electrical breakdown, oxidation and degradation of epoxy resin which is widely used to reinforce the insulating feature of various kinds of electrical apparatus. The specimen employed in this study is type A Bisphenol epoxy resin filled with MgO and Al(OH)_3, which is irradiated with UV light. A low-pressure mercury lamp is used as the source of the light, the wave lengh of which ranges from 253.7nm to 435nm. Through the experiment, the irradiation intensity is measured to be 4510㎼/㎠. The results obtained are as follows. 1. The irradiation of UV light creates the carbonyl group and causes crazes on the surface of the specimen. 2. As the duration of the irradiation of UV light is prolonged, the electrical breakdown strength decreases at different rates depending on the amount of filler in the specimen. That is, a larger amount of filler makes the specimen undergo the electrical breakdown at a lower rate.

都心 住居機能의 衰退意味와 要因에 관한 硏究

박용관,유창균 朝鮮大學校 建設技術硏究所 1998 建設技術硏究 Vol.18 No.2

This study is to secure the necessity and validity of recovering the urban dwelling function by examining and systematizing the meaning and factors of degeneration of urban dwelling functions and the concrete results of this study are as follows. 1. It is frequent that the degeneration of urban dwelling functions is interpreted as a part of temporarily necessary phenomena resulted in the stage of urban growth, but in the light of the aspects and seriousness of problems resulted from this, it is considered that the preparation of alternative for recovering its functions is very urgent. 2. The degeneration of urban dwelling functions means the decrease of population residing at urban area and the dispersion of the whole urban population according to the shift of residence and for establishing the index of degeneration, the continuous research and analysis of the current and motif of residential shift in urban area should be conducted on the basis of the understanding of urban spatial structure. 3. The degeneration of urban dwelling functions is resulted by complex effects of various factors, but since the weakening of competitiveness in urban location of housing and the lowering of environmental quality are major causes of the degeneration, the preparation of architectural planning and urban planning alternatives is required for improving this.