http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Shin, H. D.,Park, K. S.,Park, B. L.,Cheong, H. S.,Cho, Y. M.,Lee, H. K.,Lee, J.-Y.,Lee, J.-K.,Kim, H. T.,Han, B. G.,Kim, J. W.,Koh, I.,Kim, Y. J.,Oh, B.,Kimm, K.,Park, C. Blackwell Science Ltd 2006 Diabetic medicine Vol.23 No.1
<P>Abstract</P><P>Aims </P><P>Growing evidence supports the hypothesis that chronic low-grade inflammation related to innate immunity may play an important role in the pathophysiology of Type 2 diabetes mellitus (T2DM). The monocyte differentiation antigen CD14 gene (<I>CD14</I>) acts as the receptor for lipopolysaccharide (LPS) and augments monocyte/macrophage inflammatory responses.</P><P>Methods </P><P>We have sequenced the gene, including all exons, exon/intron boundaries, and the −1.5 kb of the 5′ flanking region. Two common loci (minor allele frequency > 0.05) were genotyped in 775 T2DM patients and 316 control subjects recruited in the Korean T2DM Study.</P><P>Results </P><P>Eight polymorphisms, including four non-synonymous forms, were identified in <I>CD14</I>. No polymorphisms were found in association with T2DM. However, one common promoter SNP (<I>−260T>C</I>) was significantly associated with both the serum triglyceride level (TG) and body mass index (BMI) in non-diabetic control subjects. Individuals who carried the minor allele (C) had higher TG levels (1.65 ± 0.81 vs. 1.46 ± 0.80 mmol/l; <I>P</I> = 0.0007) and BMI (23.96 ± 3.00 vs. 23.28 ± 3.22 kg/m<SUP>2</SUP>; <I>P</I> = 0.04) as compared with subjects carrying T/T genotypes.</P><P>Conclusion </P><P>Our data suggest that lipid metabolism and obesity, important pathophysiological elements of T2DM and the metabolic syndrome, are regulated by complex mechanisms that include the CD14 gene polymorphism-mediated genetic propensity to non-specific inflammatory responses.</P>
이종철,유명희,윤휘중,신영태,정순일,조보연,이문호,이명철 대한핵의학회 1981 핵의학 분자영상 Vol.15 No.1
To evaluate the diagnostic accuracy of the measurement of free thyroxine(FT4) by radioimmunoassay, we measured free T4 and T4, T3, T3RU, TSH and TBG serum levels by radioimmunoassay in 18 healthy persons and 52 patients with various thyroid diseases and 11 normal pregnant women. The results are as follows. 1) In 19 cases of overt hyperthyroidism, T3, free T4 and FTI, T4/TBG ratio reflect hyperfunction in all cases. T4 is increased in 94%(18/19) and TBG and TSH are decreased in 79%(15/19). 2) In 8 patients with overt hypothyroidism, TSH is increased in all cases and free T4 and FTI is decreased in all cases. T4 is decreased in 87.5%(7/8), T3 is decreased in 75%(6/8) and T4/TBG ratio is decreased in 62.5%(5/8). 3) In 5 patients who are clinically in euthyroid state after treatment of hyperthyroidism, T4 free T4, FTI and TSH are in the normal range in all cases and T3 is normal in 60%(3/5) and slightly increased in 40%(2/5). 4) In 10 patients who showed clinically borderline hypothyroidism after treatment of hyperthyroidism, TSH is increased in all cases and free T4 and FTI are decreased in all cases, but T4 and T3, T4/TBG ratio are in the normal limit in all cases. So after treatment of hyperthyroidism, TSH, free T4 or FTI are recommended as optimal function test. 5) In normal pregnancy, free T4, FTI and T4/TBG ratio reflect normal function, but the other parameters unreliable due to the influence of increased TBG. Also TBG and TSH level in pregnancy is increased significantly compared with normal healthy control group. 6) The coefficients of correlation between T4 and FTI were 0.862(p〈0.001) and 0.685(p〈0.001) between free T4 and T4/TBG ratio. In most patients, diagnostic value of free T4 was comparable and even superior to FTI, so free T4 measurement can be used routinely with thyrotropin assay in the diagnosis of hypothyrodism or with T3 for the diagnosis of hyperthyroidism.
Jung, S.C.,Yeom, J.A.,Kim, J.-H.,Ryoo, I.,Kim, S.C.,Shin, H.,Lee, A.L.,Yun, T.J.,Park, C.-K.,Sohn, C.-H.,Park, S.-H.,Choi, S.H. American Society of Neuroradiology 2014 American journal of neuroradiology Vol.35 No.6
<P><B>BACKGROUND AND PURPOSE:</B></P><P>The usefulness of pharmacokinetic parameters for glioma grading has been reported based on the perfusion data from parts of entire-tumor volumes. However, the perfusion values may not reflect the entire-tumor characteristics. Our aim was to investigate the feasibility of glioma grading by using histogram analyses of pharmacokinetic parameters including the volume transfer constant, extravascular extracellular space volume per unit volume of tissue, and blood plasma volume per unit volume of tissue from T1-weighted dynamic contrast-enhanced perfusion MR imaging.</P><P><B>MATERIALS AND METHODS:</B></P><P>Twenty-eight patients (14 men, 14 women; mean age, 49.75 years; age range, 25–72 years) with histopathologically confirmed gliomas (World Health Organization grade II, <I>n</I> = 7; grade III, <I>n</I> = 8; grade IV, <I>n</I> = 13) were examined before surgery or biopsy with conventional MR imaging and T1-weighted dynamic contrast-enhanced perfusion MR imaging at 3T. Volume transfer constant, extravascular extracellular space volume per unit volume of tissue, and blood plasma volume per unit volume of tissue were calculated from the entire-tumor volume. Histogram analyses from these parameters were correlated with glioma grades. The parameters with the best percentile from cumulative histograms were identified by analysis of the area under the curve of the receiver operating characteristic analysis and were compared by using multivariable stepwise logistic regression analysis for distinguishing high- from low-grade gliomas.</P><P><B>RESULTS:</B></P><P>All parametric values increased with increasing glioma grade. There were significant differences among the 3 grades in all parameters (<I>P</I> < .01). For the differentiation of high- and low-grade gliomas, the highest area under the curve values were found at the 98th percentile of the volume transfer constant (area under the curve, 0.912; cutoff value, 0.277), the 90th percentile of extravascular extracellular space volume per unit volume of tissue (area under the curve, 0.939; cutoff value, 19.70), and the 84th percentile of blood plasma volume per unit volume of tissue (area under the curve, 0.769; cutoff value, 11.71). The 98th percentile volume transfer constant value was the only variable that could be used to independently differentiate high- and low-grade gliomas in multivariable stepwise logistic regression analysis.</P><P><B>CONCLUSIONS:</B></P><P>Histogram analysis of pharmacokinetic parameters from whole-tumor volume data can be a useful method for glioma grading. The 98th percentile value of the volume transfer constant was the most significant measure.</P>
한국 밀식사과원의 정지전정에 따른 수체생장과 생산성 및 경영효율 비교
정혜웅,김경훈,송태영,홍성일,한호균,김귀권,신종협,여덕환,김병철,박준권,Jung, H.W.,Kim, K.H.,Song, T.Y.,Hong, S.I.,Han, H.K.,Kim, K.K.,Shin, J.H.,Yeo, D.H.,Kim, B.C.,Park, J.K. 국립한국농수산대학교 교육개발센터 2017 현장농업연구지 = Journal of practical agricultural resear Vol.19 No.1
The present study conducted a comparison on tree growth and productivity of high-density apple orchards by several orchard management systems: making scaffolds by heading-back and thinning out pruning (T-1), maintaining scaffolds upward and bearing shoots downward (T-2), managing branches slightly upward without heading-back (T-3), keeping leaders downward and shoots pending (T-4), maintaining leaders high and branches horizontal with severe pinching (T-5), making leaders with lower branches vigorous and upper shoots pending (T-6), and controlling very high planting density with bending branches (T-7). In conclusion, the orchards of (T-5) and (T-6) management systems showed a superior performance in controlling tree growth, productivity, and quality of fruits. Also, superior management efficiency was obtained in the orchards of (T-5) and (T-6).
차태인(T. I. Cha),신종계(J. G. Shin),김남두(N. D. Kim),정영수(Y. S. Jeong) 한국정밀공학회 2006 한국정밀공학회 학술발표대회 논문집 Vol.2006 No.5월
The worker who is responsible for Airless Pump maintenance have a high possibility to suffer from WMSDs, because a height of Airless Pump workbench is too low. In this paper, I"m going to introduce a research about 1) analysis of working environment through a interview with an actual field worker, 2) Ergonomic simulation modeling of an Ariless Pump worker to suggest a advanced working environment and a working instructions. I have used a DELMIA S/W as a tool for ergonomic simulation and performed a posture & activity to analyze a RULA methodology. Applying the Digital Human Simulation to analyze working posture would be helpful to preventing WMSDs.
Sub Bandgap Photonic Base Current Method for Characterization of
H. T. Shin,K. H. Kim,D. J. Kim,D. M. Kim,D. W. Kang,H. S. Park,H. T. Kim,I. C. Nam,J. B. Choi,J. U. Lee,K. S. Min,K. S. Kim,S. W. Kim,T. E. Kim 한국물리학회 2004 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.44 No.6
In this paper, we propose a novel photonic base current analysis method to characterize the interface states in heterojunction bipolar transistors (HBTs) by using the photonic I-V characteristics under sub-bandgap photonic excitation. For the photonic current-voltage characterization of HBTs, an optical source with a photon energy less than the bandgap energy of Al0:3Ga0:7As and GaAs (Eph = 0.95 eV < Eg;AlGaAs = 1.79 eV & Eg;GaAs = 1.45 eV) is employed for the characterization of the interface states distributed in the photo-responsive energy band (EC - 0.95 Eit EC) in emitter-base heterojunction at HBTs. The proposed novel method, which is applied to bipolar junction transistors for the rst time, is simple, and an accurate analysis of interface traps in HBTs is possible. By using the photonic base-current and the dark-base-current, we qualitatively analyze the interface trap at the Al0:3Ga0:7As/GaAs heterojunction interface in HBTs.
Conjugated Linoleic Acid(CLA) 급여가 난황의 콜레스테롤과 CLA 함량에 미치는 효과
이정일,박구부,박태선,김진형,신택순,강석중,하영래,주선태 한국축산학회 1999 한국축산학회지 Vol.41 No.1
The effects of dietary conjugated linoleic acid (CLA) on the concentration of cholesterol and CLA in egg yolk were investigated. CLA was synthesized according to the method of Alkali isomerization using safflower oil. A total of 250 hens (200 days age) were fed a control diet (a commercial laying hen feed) or CLA-supplemented diets (T1 ; 1% CLA and 4% safflower oil, T2; 2.5% CLA and 2.5% safflower oil, T3; 5% CLA, and T4; 5% safflower oil) for 6 weeks. Eggs were collected for analysis of CLA, cholesterol and fatty acid levels in the yolk. CLA concentration in egg yolk was increased by level of dietary CLA or dwation of feed. The yolk CLA concentration of T3 rapidly increased for 2 weeks, and maintained there after. On the other hand, the concentration of T4 was not significantly different from that of control during the feeding period. These results implied that CLA could not be synthesized by hen and it was necessary to supplement the diet with CLA for CLA accumulation in egg yolk. The level of CLA in egg yolk depended on the amount of CLA supplemented, and over-supplementation of CLA was not necessary. As the yolk CLA increased, the levels of cholesterol, linoleic acid and arachidonic acid decreased but that of palmitic acid increased. It was suggested that a lowcholesterol egg might be produced with over 1% CLA-supplemented diet. The concentration of CLA in egg yolk was unchanged during 28 days storage at 4℃. However, the level of cholesterol decreased during the storage.