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      • 矮化劑 處理가 바나나의 生育 및 收量에 미치는 影響

        李宗錫,姜榮吉,朴才昊,韓海龍,文斗吉,金龍湖 濟州大學校 亞熱帶農業硏究所 1990 亞熱帶農業硏究 Vol.7 No.-

        바나나에 알맞은 矮化劑를 選拔하고자 몇종의 矮化劑를 Dwarf Cavendish에 처리하였던 결과를 요약하면 다음과 같다. 1. 주당 80mg 이하의 paclobutrazol 土壤灌注 처리는 草長, 莖葉特性, 果實收量, 果實特性 등에 영향을 주지 않았다. 200mg 이상 처리구에서는 草長과 假莖長이 단축되는 경향을 보였고 果梗長은 유의성 있게 단축되었으나 다른 莖葉特性이나 果實收量, 果實特性은 무처리구와 큰 차이가 없었다. 2. 주당 20mg의 ancymidol 土壤灌注에 의해서 草長과 假莖長이 단축되는 경향이나 다른 莖葉特性이나 果實收量, 果實特性은 무처리구와 큰 차이가 없었다. 3. 5000ppm의 chlormequat 수용액 2회 葉面撤布區에서는 草長, 莖葉特性, 果實收量, 果實特性 등이 무처리구와 비슷하였다. 4. 草長과 假莖을 현저히 단축시키는 藥量의 矮化劑를 처리할 때 果梗이 假莖에서 빠져나오지 못할 것으로 보여 바나나에 있어서 矮化劑의 실용성은 없을 것 같다. This study was conducted to select growth retardants for bananas grown in a plastic greenhouse. The various rates of paclobutrazol(40, 80, 200 and 400mg/plant) and 20mg/plant of ancymidol were soil drenched and 5000ppm solution of chlormequat was foliarly sprayed twice. Application of less than 80mg of paclobutrazol did not affect plant height, pseudostem and leaf characteristics fruit yield and fruit characteristics. Application of 200 or 400mg of paclobutrazol tended to reduce plant height and pseudostem length and significantly shortened fruit stalk but did not affect the other characteristics. Application of 20mg of ancymidol tended to reduce plant height and pseudostem length but did not influence the other characteristics. Foliar spray of 5000ppm solution of chlormequat did not influence any measured plant traits. Application of growth retardants to bananas grown in a plastic greenhouse may not be beneficial because growth retardant rates to reduce plant height and pseudostem length significantly appear to prevent fruit stalks from fully emerging.

      • Platycodon grandiflorum root-derived saponins attenuate atopic dermatitis-like skin lesions via suppression of NF-kB and STAT1 and activation of Nrf2/ARE-mediated heme oxygenase-1

        ( Jae Ho Choi ),( Sun Woo Jin ),( Eun Hee Han ),( Bong Hwan Park ),( Hyung Gyun Kim ),( Tilak Khanal ),( Yong Pil Hwang ),( Minh Truong Do ),( Hyun Sun Lee ),( Young Chul Chung ),( Hee Suk Kim ),( Tae 영남대학교 약품개발연구소 2014 영남대학교 약품개발연구소 연구업적집 Vol.24 No.0

        Purpose: The consequences of precipitously rising allergic skin inflammation rates worldwide have accelerated the risk of atopic dermatitis (AD). Natural product-based agents with good efficacy and low risk of side effects offer promising prevention and treatment strategies for inflammation-related diseases. We have already reported that Platycodon grandiflorum root-derived saponins (Changkil saponins, CKS) have many pharmacological effects, including anti-inflammatory and anti-allergic effects, but its influence on AD remains unclear. Therefore, we evaluated the inhibitory effect of CKS, mainly platycodin D, on AD-like skin symptoms in mice and the possible mechanisms in cells. Methods: Mice were sensitized and challenged with 2,4-dinitrochlorobenzene (DNCB). Four weeks after challenge, mice were treated with oral administration of CKS for 4 weeks. In addition, cells were used to evaluate the effect of CKS, mainly platycodin D, on the TARC expression regulated mechanism. Results: CKS attenuated DNCB-induced dermatitis severity, serum levels of IgE and TARC, and mRNA expression of TARC, TNF-α, IFN-γ, IL-4, IL-5, and IL-13 in mice. Histopathological examination showed reduced thickness of the epidermis/dermis and dermal infiltration of inflammatory cells and mast cells in the ears. Moreover, CKS and platycodin D inhibited TNF-α/IFN-γ-induced TARC expression through the suppression of NF-κB and STAT1 and induction of Nrf2/ARE-mediated hemeoxygenase-1 (HO-1) expression in cells. Conclusion: We suggest that CKS and platycodin D inhibited the development of AD-like skin symptoms by regulating cytokine mediators and may be an effective alternative therapy for AD-like skin symptoms.ⓒ2014 Elsevler Gmbh. All rights reserved.

      • Accuracy on the Edge Detection of Topography for Digital Map Manufacture

        Park, Woon-Yong,Song, Youn-Kyung,Bae, Kyung-Ho,Kim, Yong-Suk 東亞大學校 建設技術硏究所 2005 硏究論文集 Vol.28 No.2

        Currently, digital maps in the metropolitan area are supposed to be revised and renewed every two years, but it is difficulty for the renewal of current information to keep pace with the quickly changing society and so, one of the alternative methods being discussed is a digital map produced using high resolution satellites. The biggest problem in the production of digital maps using high resolution satellite images is the difficulty of production in vector resource format through edge detection of satellite images, a Raster data. In this study, topographical boundaries were detected through edge detection of the satellite image, and after vectorliezing using the screen digitizing method, the results were evaluated and compared to the digital map from the NGII(National Geographic Information Institute) for accuracy.

      • KCI등재
      • 레저스포츠 참여와 여가만족의 관계

        김용인,정갑석,장호중,김정묵,정석현 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.1

        The purpose of this study was to examine the relationship between participation in leisure sport activities of leisure satisfaction. To accomplish this research purpose, there were two research questions; Firstly, Is there difference on leisure satisfaction according to the participation in leisure sport activities?, Secondly Will the degree of participation in leasure sport activities influence the leisure satisfaction? The population for this study was participants in Leisure sports activity program located in Seoul. The final 227 responses (participation 163, non-participation 114), collected by cluster random selecting method, were used in the data analysis procedure. The items for measuring leisure satisfaction were largely based on Lee(1992)s study, and the degree of participation in leisure sport activities was measured by the period and frequence of participation. To analyze the final data (277), the reliability analysis, analysis of covariance, multiple classification analysis, and multiple regression analysis were used. The conclusions for this study were as followings; Firstly, leisure satisfaction is partially different by participation yes or no of the leisure sports activity. That is, leisure satisfaction is higher participation of leisure sports activity than non-participation Secondly, leisure satisfaction is partially influence by the participation of degree of leisure sports. That is, period and frequence are influence on leisure satisfaction.

      • 고효율 DC/DC컨버터 제작을 위한 동기정류기 도전 손실 해석

        윤석호,김용,백수현,김필수 동국대학교 산업기술연구원 1999 산업기술논문집 Vol.14 No.-

        최근 반도체 소자의 제조기술 발달로 정보통신기기 등에 사용되는 온보드(on-board) 컨버터의 전원전압은 3.3V 또는 1.5V의 저전압 전원이 사용된다. 이러한 저전압 전원방식은 온보드(on-board) 컨버터의 정류기단 전력손실이 증가하게 되어 시스템의 높은 효율을 얻기가 어렵게 된다. 낮은 전원전압 방식일수록 정류기단에서 전력손실은 더욱 증가하여 컨버터의 효율은 낮아진다. 고전력밀도의 정류기단 구성을 위하여 출력단에 다이오드 대신 MOSFET 자기구동 정류기를 사용한다. 그러나 MOSFET 자기구동 정류기의 전력손실은 2차측 구동전압의 형태나 기생인덕턴스의 영향을 받게 된다. 따라서 불연속에서는 기생인덕턴스에 의한 MOSFET와 쇼트키 다이오드의 도통주기의 변화가 MOSFET 자기구동 정류기의 전력손실에 미치는 영향을 분석하였으며, 그 결과 기생인덕턴스의 크기를 감소시켜 MOSFET의 도통주기를 증가시킴으로써 MOSFET 자기구동 정류기의 전력손실을 최소화하였다. Recently, new trend in telecommunication device is to apply low voltage, about 3.3V-1.5V. However, it is undesirable in view of high efficiency and power desity which is the most important requirement in the distributed power system. Rectification loss in the output stage in on-board converter for distributed power system are constrained to obtain high efficience at low output voltage power supplies. This paper is investigated conduction power loss in synchronous rectifier with a parallel connected Schottky Barrier Diode(SBD). Conduction losses are calculated for both MOSFET and SBD respectively. The SBD conduction power loss dissipates more than the MOSFET rectifier conduction power loss.

      • 사구체 수의 증감을 비교할 수 있는 기준 개발

        김용진,이지은,이국주,최영호,홍정석 영남대학교 기초/임상의학연구소 2001 Yeungnam University Journal of Medicine Vol.18 No.1

        Background: The number of glomerulus has been considered one of the etiologic factors especially for focal segmental glomerulosclerosis. However, glomeruli are too many to calculate them correctly. Although the fractionator method has became convinced, in which they used selected sections, not whole kidney sections, with same intervals, it is also very hard to get good results. Because it is still very time-consuming and laborous work which leads to make big observers' biases. Methods and Materials: We designed the index for glomerular number to estimate the tendency of increase or decrease of the number of it in different kidneys and which was evaluated by other conventional methods including fractionator method. Index was based upon the theory by Nyengaard; "the number of glomerulus correlates with the weight of kidney, which is positively correlated with body weight". Calculating formula is the number of glomeruli/surface areas of cortices, which contain calculacted glomeruli multiplies by kidney weight/body weight. Results: We applied this index to kidneys of FGSKist mouse and those of RFM/Nga mouse. The former is spontaneous glomerulosclerosis model with heavy protein uria and renal faille and the latter is the mother side of FGS/Kist mouse but has no glomerular disease or protein aria. The number of glomerulus of FGS/Kist mouse was decreased by 30% to those of RFM/Nga mouse. Conclusion: This index was useful and reliable for estimating the relative glomerular number between two groups.

      • KCI등재후보

        말기 신부전 환자에서 투여 경로에 따른 유전자 재조합 인 Erythropoietin(Epokine^(�))의 효과와 안정성에 대한 연구 : 제 4상 연구 A Phase 4 Single Center Study

        송현용,윤향숙,강신욱,최규헌,하성규,이호영,한대석 대한신장학회 2002 Kidney Research and Clinical Practice Vol.21 No.2

        목 적 : 국내 독자적 기술로 첫 개발된 유전자 재조합 인 에리트로포에틴(Epokineⓡ)의 투여방법에 따른 유효성과 안정성을 알아보고자 하였다. 방 법 : Epokineⓡ을 주당 100-150 U/kg, 주 2회, 12주간 피하 주사하여 목표 또는 안정된 혈색소치 유지 후 무작위로 피하 및 정맥 주사군으로 나누어 12주간 혈액투석 및 복막투석 환자13명, 28명에서 유효성, 안정성을 분석하였다. 결 과 : 양군에서 혈색소치와 헤마토크릿은 Epokineⓡ 투여 2주 후부터 증가, 혈색소치가 혈액투석 환자는 투여 전 7.3 g/dL, 투여 12주 9.5 g/dL, 24주 10.6 g/dL로, 복막투석 환자는 6.8g/dL에서 12주 10.2 g/dL, 24주 10.8 g/dL로 증가하였다. 양군에서 교정 망상적혈구수(%)는투여 1주 후부터 전 기간동안 증가하였다. 혈청 내 철분, ferritin치는 양군에서 투여 2주 후부터감소, 총 철분 결합능은 투여 2주 후부터 증가하였다. 12주째 혈액투석 환자에서 많은 Epokineⓡ용량이 필요했으나(142.2±20.5 vs 117.3±33.6 U/kg/wk, p<0.001) 24주 후 양군의 용량차이는 없었다(123.6±41.5 vs 99.2±49.3 U/kg/wk, p>0.05). 혈액투석 환자에서 피하 주사가Epokineⓡ 투여용량이 더 적었으나(97.4±15.4 vs 145.4±2.9 U/kg/wk, p<0.002) 복막투석 환자는 차이가 없었다(93.0±60.2 vs 105.4±9.7 U/kg/wk, p>0.05) 연구기간 중 9명(18.8%)에서혈압강하제 추가가 필요한 혈압상승, 근육통 동반 상기도 감염 유사증상 및 두통 등의 부작용이 있었다. 대부분 자연소실 혹은 대증요법으로 치유되었고 2명이 부작용으로 탈락하였다. 결 론 : 말기 신부전 환자의 빈혈 개선에 사용하는 Epokineⓡ의 효과는 복막투석 환자에서 더 좋았으며 투여 경로는 정맥주사보다 피하주사가 높음을 알 수 있었다. Background : We evaluated the clinical efficacy and safety of recombinant human erythropoietin(Epokine^(ⓡ)). Methods : A comparative prospective study of intravenously and subcutaneously administrated Epokine^(ⓡ) conducted 13 patients performing hemodialysis and 28 patients performing continuous ambulatory peritoneal dialysis with end-stage renal disease. Epokine^(ⓡ) was given initially at a dosage of 100 unit/kg, subcutaneously, two times a week. The patients had achieved stable or more than 10 g/dL of hemoglobin level for 12 weeks and then we randomized switching intravenously or subcutaneously administrated Epokine^(ⓡ) for another 12 weeks. Results : Hemoglobin(g/dL) and hematocrit(%) increased significantly from baseline levels beginning from 2 weeks after Epokine^(ⓡ) administration. In HD patients, hemoglobin increased significantly from 7.3 to 9.5 after 12 weeks and to 10.6 after 24 weeks. In CAPD patients, hemoglobin increased significantly from 6.8 to 10.2 after 12 weeks and then 10.8 after 24 weeks(p<0.05). Corrected reticulocyte count(%) was significantly increased from baseline levels beginning from 1 week after Epokine^(ⓡ) administration and continuously increased during study period in both group. Serum ferritin and serum iron decreased significantly and total iron binding capacity increased significantly after 2 weeks. At 12 weeks, HD patients were significantly needed more dosage of Epokine^(ⓡ) than CAPD patients(142.2±20.5 vs 117.3±33.6 U/kg/wk, p<0.001), but at 24 weeks, the dosage was not different(123.6±41.5 vs 99.2±49.3 U/kg/wk, p> 0.05). In HD patients, intravenously administrated Epokine^(ⓡ) group was more dosage than subcutaneously group(97.4±15.4 vs 145.4±2.9 U/kg/wk, p< 0.002), but CAPD patients were not different by administration method(93.0±60.2 vs 105.4±9.7 U/kg/ wk, p>0.05). The 9 cases(18.8%) were suffered from headache and flu-like syndrome, but these side effects were not severe and disappeared from conventional therapy. Conclusion : Epokine^(ⓡ) administration is safe and effective in treating anemia of ESRD patients and subcutaneously administration is significantly more effective than intravenously. (Korean J Nephrol 2002;21(2):190-198)

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