Development of bioadhesive gels for enhanced local anesthetic effects

Shin SC,Lee JW,Oh IJ 대한약학회 2000 大韓藥學會 總會 및 學術大會 Vol.49 No.-

질트리코모나스 질염의 Tinidazole 1회 대량투여법의 치료성적

신순철(SC Shin),박재일(JI Park),나건영(KY Na) 대한산부인과학회 1976 Obstetrics & Gynecology Science Vol.19 No.4

The purpose of this study was to access the effectiveness of single 2gm dose of Tinidazole a dertivative of imidazole, in 49 patients suffering from trichomonas vaginalis vaginitis. The aim of this study can be summarized as follows; 1. The inverstigate the safety and tolerance of tinidazole. 2. To determine the optimal dose and duration of therapy on trichomonas vaginalis vaginitis with tinidazole. In all patients the following laboratory tests were carried out ; SGOT, SGPT, alkaline phosphatase serum bilirubin, total and differential white cell count, and BUN for evaluation of drug toxicity. At the same time any side effect was observed. Results; In all patients and their husbands, tinidazole 2gm was administered at one time by mouth only, and wet smear and culture were conducted on 1wk and 4wks later for assesing the evidence of cure. 1. Side effects were appeared 11 cases (22.4%) such as abdominal discomfort, anorexia, dry mouth, verigo, and headache. But they were mild or moderate. 2. Toxicity ; only 2 cases (4.1%) were showed SGOT level increasing on post treatment 1wk, but they were returned normal level on post-treatment 4wks 3. Clinical symptoms and signs were imporved within post-treatment 1wk in 95%. 4. Cure rate ; post treatment 1wk ; 98% post treatment 4wks ; 92%

난소 미성숙기형종 1 례

신면우,김승철,송현진,성영미,김광준,송명화 대한산부인과학회 1994 Obstetrics & Gynecology Science Vol.37 No.11

저자들은 본 병원에서 난소 미성숙기형종 1례를 경험하고 수술후 PVB regimen에 따른 항암화학요법을 시행하여 호전중인 환자를 문헌고찰과 함께 보고하는 바이다. Immature teratoma of the ovary is a highly lethal, rare germ cell origin tumor. This tumor represents only 1% of all ovarian teratomas and occurs most commonly in children and young adults. The immature teratoma is composed of various quantities of immature tissue differentiating toward any or all three germ layers. Symptoms are abdominal pain, tenderness and palpable mass on abdomen or pelvis.

자궁경부암 414 례의 임상적 분석 및 치료성적

신면우,김승철,최광엽,박정온,고용석,최도형 대한산부인과학회 1994 Obstetrics & Gynecology Science Vol.37 No.5

중앙 길병원 산부인과에서는 1989년 3월부터 1993년 3월까지 중앙길병원 산부인과와 치료방사선과에서 자궁경부암으로 진단 및 치료받은 414예의 임상양상과 임상병기별 생존율을 구하여 다음과 같은 결과를 얻었다. 1. 년도별 환자분포는 1989년 67명, 1990년에 88명, 1991년에 90명, 1992년에 139명, 1993년 3월까지는 30명이었다. 2. 연령별 분포는 50-59세군, 40-40세군, 30-39세군의 순서로 많았으나 각각 전체 환자의 25.6%, 24.5%, 24.2%를 차지하여 50대, 40대, 30대가 거의 유사한 발생빈도를 보였다. 3. 임상병기별 분포는 I기가 50.0%로 가장 높은 빈돌ㄹ 보였으며, II기: 24.9%, 0기: 13.7%, III기: 8.5%, IV기: 2.9%였다. 4. 조직병리학적 분포는 편평상피 세포암이 96.6%, 선암이 2.9%, 선편평상피 세포암이 0.5%였다. 5. 임파절전이는 Ia기에서는 3.7%, Ib기에서는 16.9%, IIa기에서는 19.6%였다. 6. 종괴의 크기를 2 cm이하, 2-4 cm, 4 cm이상으로 하였을 때 Ib기인 경우 골반임파절 전이빈도는 각각 10.5%, 20.5%, 35.5%이고, IIa기인 경우에는 각각 10.0%, 14.3%, 62.5%로 종괴의 크기가 클수록 임파절 전이 빈도도 증가하고 있다. 7. 생명표법(life table method)에 의한 침윤성 자궁경부암 I기의 52개월 생존율 1) 대상환자는 Ia기 27예, Ib기 180예였다. 2) 52개월 생존율은 Ia기 100%, Ib기 91.7%였다. 8. Kaplan-Meier method에 의한 침윤성 자궁경부암 IIa기, IIb기, III기의 생존율 1) 대상환자는 IIa기 58예, IIb기 45예, III기 35예였다. 2) IIa기의 45개월 생존율은 86.7%, IIb기의 49개월 생존율은 58.9%, III기의 52개월 생존율은 42.9%였다. 414 cases of uterine cervical cancer, diagnosed and treated from march 1989 to march 1993, were evaluated at Jung-Ang Gils general hospital, Incheon, Korea. The purpose of this study was to analyze the clinical profile and survival rate of cervical cancer. The number of patients were 67 cases in 1989, 88 cases in 1990, 90 cases in 1991, 139 cases in 1992 and 30 cases in 1993. The age distribution of patients were similar in the age group of 50s (25.6%), 40s (24.5%) and 30s (24.2%). The distriution of patients by the clinical stage were as follows: Stage 0, 57 cases (13.7%); Stage 1,207 cases (50.0%); Stage II, 103 cases (24.9%); Stage III, 35 cases (8.5%); and Stage IV, 12 cases (2.9%). The histopathologic types were as follows:Squamous cell carcinoma was 96.6%, adenocarcinoma was 2.9% and adenosquamous cell carcinoma was 0.5%. The frequency of pelvic lymph node metastasis was 3.7% in stage Ia, 16.9% in stage Ib and 19.6% in stage IIa. The incidence of pelvic node metastasis correlated with the size of the tumor, in stage Ib, was 10.5% for tumors less than 2 cm in diageter, 20.5% for tumors 2 to 4 cm, and 35.7% for tumors up to 4 cm. In stage IIa, the incidence was 10.0% for tumors less than 2 cm, 14.3% for tumors 2 to 4 cm, and 62.5% for tumors up to 4 cm. We have evaluated the survival rate by life table method for stage Ia and Ib, and by Kaplan-Meier method for stage IIa, Iib and III$gt; The results were as follows; 100% 52 month survival rate for stage Ia; 91.7% 52 month survival for stage Ib; 96.7% 45 month survival for stage IIa; 58.9% 49 month survival for stage IIb; 42.9% 52 month survival for stage III.

고 Prolactin혈증 일란계분뇨일무월경증후군 치험 2례

이승철(SC Lee),이제호(JH Lee),신희철(HC Shin),김승욱(SW Kim) 대한산부인과학회 1982 Obstetrics & Gynecology Science Vol.25 No.1

Nowadays H-G-A syndrome and its management is one of matters of concern in obstetric and gynecologic field. Authors have experienced two cases of infertility with H-G-A syndrome which were managed successfully to induce regular ovulatory cycle or to become pregnant, with bromocriptine or clomiphene and human chorionic gonadotropin resepctively.

선택적 Cyclooxygenase-2 억제제가 누드마우스에 이종이식한 인체 전립선암세포의 세포고사에 미치는 영향

오승령,신지현,안재호,노보상,안승현,김태형,명순철,김영선,방효원,이태진 大韓泌尿器科學會 2003 Korean Journal of Urology Vol.44 No.10

재일한국인(在日韓國人)의 장래(將來) 인구추기(人口推記)

김윤신 ( Yoon Shin Kim ),( Dr H Sc ) 한국보건사회연구원 1982 保健社會硏究 Vol.2 No.2

This paper presents firstly population projections for Koreans in Japan by age and sex up to the year of 2050 based on the 1975 census population. Under the assumption that age-specific fertility and mortality in 1975 was constant, the projected population was reestimated with consideration of increasing naturalization. As the results of the projections, the aged population are increased up to 2050. Total age dependency ratio is reached to 57.1% in 2050 whereas the age dependency ratio is 22.1% in 2050. The projected number of population are approximately 670,000 in 1990, 730,000 in 2000, 840.000 in 2025, and 880,000 in 2050.

유방섬유종절제술 환자에서 Propofol 목표농도조절주입을 이용한 마취유도 후 기관내삽관에 따른 혈압 및 심박수의 변화와 Ketamine의 선행진통효과

유용준,이정은,신용섭,이원형,손수창,최재호 대한정맥마취학회 2003 정맥마취 Vol.7 No.3

질에 발생한 원발성평활근육종 1 예

김흥곤,문형배,신무철,윤기중,권상철,조향정 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.1

The vagina is an infrequent site of primary sarcomas, which are less than 2% of all malignant vaginal neoplasm. The most common malignant mesenchymal tumor of the vagina is rhabdomyosarcoma, but leiomyosarcoma is rare type tumor of the vagina. Microscopically, spinle cells with pleomorphic nuclei and mitotic figures were frequently noted, but cross-striations were not found in the tissue. Alpha-smooth muscle actin and desmin were positive, but sarcomeric actin was negative in the tumor cells. The authors report a case of primary leiomyosarcoma of the vagina with brief literature review.

임신말기 산모의 chlamydia Trachomatis감염률 조사

오승재(SJ Oh),박성철(SC Park),신경숙(KS Shin),윤경(K Yun),안재영(JY Ahn) 대한산부인과학회 1986 Obstetrics & Gynecology Science Vol.29 No.1

1985년 1월부터 1985년 7월까지 7개월간 서울 고려병원 분만실에 내원한 환자 중 무작위로 선별된 297예의 임신말기 산모와 60예의 신생아를 대상으로 산모에서는 분만전 자궁 경부에서 검체를 채취하였고 신생아에서는 결막(conjunctiva)과 인후(throat)에서 검체를 채취하여 McCoy 세포를 사용한 chlamydia 배양법을 시행하여 다음과 같은 결과를 얻었다. 1. 무작위로 선별된 297예의 임신말기 산모 중 chlamydia 배양검사에 의한 양성율은 20.8%이었다. 2. 연령별로는 20~24세의 군이 가장 높은 양성율을 보였고, 임신주수에서는 35~38주에서 양성율이 높았다. 3. 경산부와 초산부사이에 양성율의 차이는 없었고, 기왕력에 유산 경험이 있는 산모가 경험이 없는 산모보다 높은 양성율을 보였다. 4. 신생아 체중과의 관계에서는 신생아 체중이 적을 수록 산모의 양성율이 높은 경향을 보였으며 조기 파막의 유무와 산모의 양성율과는 관계가 없었다. 5. 무작위로 선별된 60예의 신생아 중 chlamydia 배양검사에 의한 양성율은 20.0%이었으며, 17예의 양성 산모에서 태어난 신생아 중 12예에서 양성 반응을 나타내 70.0%의 신생아 이환율을 보였다. Detection test of chlamydia trachomatis in the cervix of randomly selected 297 term pregnant women and 60 new born infants was performed using Mc Coy cell culture during the period from January 1985 to July 1985. The following results were obtained: 1. The positive detection rate of chlamydia trachomatis in 297 cases of term pregnancy was 20.8%. 2. There was a tendency of increasing positive rate both in age group of 20 to 24 and in gestational week of 35 to 38. 3. No significant difference in positive rate was found in group of primipara and multipara, however, patient with past history of abortion showed much higher positive rate as compared with patients without history of abortion. 4. There were tendency of higher positive rate in term pregnant mothers delivered infants with lower birth weight and there was no significant difference in positive rate between the spontaneous premature rupture of membrane and intact membrane at time of delivery. 5. The positive detection rate ofchlamydia trachomatis in the conjunctiva and throat of 60 new born infants was 20.0% and 12 positive new-borns were born of 17 positive term pregnant women that comprised 70.0% of infectivility to the infants.