하악골운동 추적을 위한 단순기록장치 고안에 관한 연구

김상수,윤창근,Kim, Sang-Soo,Yoon, Chang-Keun 대한치과보철학회 1987 대한치과보철학회지 Vol.25 No.1

The purpose of this study was to improve limitations and disadvantages of the mechanical pantograph and the Visi-Trainer, and to design the reliable and reproducible device mandibular movement tracking device (MMTD) that is more simple, convenient and save the chair time than the mechanical pantograph and Visi-Trainer. MMTD was consist of head frame, horizontal bar, condylar path tracking stylus holders, anterior path tracking stylus holder, two condylar path plastic recording plates, one anterior path plastic recording plate, toggles and open occlusal clutch. To prove the reliability and reproducibility of MMTD, a five adults were selected and mandibular condylar movement was recorded one time by the mechanical pantographic tracing and MMTD. The border movement recording of the mandibular incisor (frontal, sagittal and horizontal) was also recorded by Visi-Trainer and the MMTD. The obtained results were as follows; 1. The condylar movement path (sagittal, horizontal) of the MMTD was not coincidence with that of mechanical pantograph. 2. Measurements of the angulation which established between working and balancing path records by use of the mechanical pantograph and MMTD, there was no significance. 3. In a view of MMTD's reproducibility, there was revealed almost similar recording pattern. 4. The border movement recording of the mandibular incisor by the MMTD and the Visi-Trainer showed almost same reliability and reproducibility. 5. The subjects were able to his original mandibular movements by use of open occlusal clutch in the MMTD.

폐결핵(肺結核) 환자(患者)에서 수소(愁訴)가 치료과정(治療過程)에 미치는 영향(影響)

김상수,Kim, Sang-Soo 대한예방의학회 1982 예방의학회지 Vol.15 No.1

In order to investigate the relation of subjective complaints to objective course of treatment in pulmonary tuberculosis, one hundred and seventy four cases registered at the University Health Center in Chonnam University were divided into two groups, complaint group and non-complaint group. By analysing the record at the University Health Center during these seven years from 1973 to 1979, following results were obtained: 1. In complaint group who had subjective symtoms, thirty eight cases(77.6%) among forty nine cases were detected. at clinic visit. In non-complaint group who had not any symtoms, one hundred and twenty one cases (96.8%) among one hundred and twenty five cases were detected at compulsive physical examination. 2. Comparisons of complaint group with non-complaint group were not statistically significant in many aspects, but significantly higher cases were discharged at the University Health Center to receive other medical service in complaint group than in non-complaint group. (6.1% vs 0.8%, respectively) On the contrary, non-complaint group refused medication more than two times compared with complaint group in the course of treatment (29.9% vs 12.2%, respectively). 3. In the average time lag from initial diagnosis to initial treatment, comparisons between complaint vs non-complaint group were significant (7.8 vs 28.3 days, respectively). 4. Subjective symptoms were thought to create motivation to receive therapy, and influence of motivation to therapy was strong at initial stage but it become weaker as time passed.

복재 신경의 혈관망을 이용한 원위도상 도서형 신경피부 피판술

김상수,김동철,김용범,Kim, Sang-Soo,Kim, Dong-Churl,Kim, Yong-Bum 대한미세수술학회 2001 Archives of reconstructive microsurgery Vol.10 No.1

Introduction : The goal in the management of soft tissue injuries of the lower extremity is to obtain a closed stable wound as soon as possible. Recently, An anatomic study that has shown the role of the vascular axis that follows the superficial sensory nerves in supplying the skin developed the concept of a neuroskin island flap. It has been suggested that skin island flaps supplied by the vascular network of the saphenous nerve is one of the most reliable treatment to skin defect below the knee joint. Purpose : The aim of this article is to present a clinical experience of neuroskin island flaps based on the saphenous nerve and to estimate the clinical utilities of distally based saphenous neuroskin flap. Materials and Methods : From September 1995 to May 2000, a total 12 distally based neuroskin island flaps supplied by the vascular axis of the saphenous nerve were performed to cover defects in pretibial area below the knee. Result : flap necrosis due to reactivation of existing infection developed in a case that skin defect had been on infected nonunion site of tibia. But other 11 cases survived completely without any specific complications. Conclusion : The distally based neuroskin pedicled island flap using the vascular network of the saphenous nerve are versatile and reliable and especially indicated for limited defects in pretibial area below the knee joint which are not good indications for other better-known flaps.

GST 융합 시스템에서 나타나는 macrophage migration inhibitory factor의 tautomerase 활성 저해에 관한 연구

김상수,김경희,박효진,허은혜,임향숙,Kim Sang-Soo,Kim Kyung-Hee,Park Hyo-Jin,Hur Eun-hye,Rhim Hyangshuk 한국생명과학회 2005 생명과학회지 Vol.15 No.6

Cytokine으로 처음 밝혀진 macrophage migration inhibitory factor (MIF)는 다양한 생물학적 활성 및 효소적 활성을 지닌 단백질로 알려지고 있다. 아직까지 MIF의 서로 다른 활성간의 연관성 및 효소적 기능이 세포내에서 어떤 역할을 하는지는 명확하게 밝혀지지 않았다. 본 연구에서는 MIF가 지닌 효소적 활성 중 tautomerase활성에 대하여 좀더 자세하게 연구하였다. 먼저, GST 융합 시스템을 이용하여 MIF의 정제 조건을 확립하였다. 이를 통해서 얻어진 GST (glutathione S-transferase)-MIF와 MIF 간의 활성을 비교하여 N-말단의 GST에 의하여 MIF의 tautomerase활성이 완전히 저해되는 것을 확인하였다. 다음으로, GST 대신 N-말단에 존재하는 매우 짧은 아미노산 잔기가 MIF의 tautomerase 활성을 저해하는 지를 조사하고자, GST-MIF의 GST를 thrombin으로 제거한 tMIF를 사용하였다. 그 결과 tMIF도 GST-MIF와 마찬가지로 tautomerase 활성이 완전히 저해된다는 사실을 확인할 수 있었다. 추가로 N-말단 tag에 의한 MIF의 효소적 활성 저해가 단백질의 구조적인 변환에 의한 것인지를 조사하기 위하여 단백질 cross-linking 연구를 수행하였다. 단백질 cross-linking 결과 tMIF도 MIF와 같이 정상적으로 oligomer를 형성하는 것을 확인하였다. 이들 결과는 MIF의 N-말단 $P^{2}$를 중심으로 하는 소수성 활성부위의 노출이 tautomerase활성에 결정적인 역할을 한다는 것을 시사한다. 또한 본 연구결과는 세포내에서 MIF가 다른 단백질과의 상호결합에 의해서도 충분히 tautomerase활성이 저해될 수 있을 것이라는 가능성을 제시한다.lelopathy 효과가 있음을 밝혀냈다. 특히 화본과 사료작물의 경우 italian ryegrass, 콩과 사료작물의 경우는 purple alfalfa가 생장억제효과가 높게 나타났다. 영향을 미치지 못했다. 이상의 결과를 종합하면 현재의 체형, 체형에 대한 인식, 매스컴의 영향 등이 체형에 대항 불만족이라는 스트레스로 인지되고, 이러한 이지된 스트레스와 체중조절 행동에 대한 태도가 체중조절 행동의도를 갖도록 하는 것으로 보인다. 특히 다이어트 행동에 대한 태도는 행동결과에 대한 신념이 주요 변수였음을 감안할 때 체형에 대한 불만족을 유발하는 요인들과 감안할 때 체형에 대한 불만족을 유발하는 요인들과 다이어트 행동 결과에 대한 신념이 주요 변수였음을 감안할 때 체형에 대한 불만족을 유발하는 요인들과 다이어트 행동 결과에 대한 신념이 체중조절 행동을 유발하는 주요 요인인 것으로 판단된다. 따라서 과잉 체중조절의 확산을 억제하기 위해서 현재 자신의 체형과 바람직한 체형의 기준에 대한 바른 인식을 갖도록 하는 것이 필요하다. 그리고 체형에 대한 사회적 인식이 중용한 스트레스 요인임을 감안하여 사회 전반에 만연되어 있는 바람직한 체형에 대한 인식의 변화를 위한 노력이 행해져야 한다. 또한 신념이 행동의도에 큰 영향을 미친다는 결과에 따라 다이어트 행동 결과에 대한 신념이 올바른 지식에 근거한 바람직한 신념으로 변화될 수 있도록 하여야 할 것이다. 또한 본 연구에서는 영양지식이 다이어트 행동의도에 아무런 영향을 미치지 않은 것으로 나타났다. 그러나 단기간에 실시한 영양지식의 교육이 행동의 변화까지는 영향을 미치지 않았으나 태도에는 영향을 미친 것을 참고하여 장기적인 목표를 갖고 영양 지식의 보급에도 힘을 기울여야 하겠다.큰 것으로 보인다.의 경우 압흔과 함께 pitting 이 관찰되며, Ormco Stainless Steel의 Macrophage migration inhibitory fartor (MIF), known as a cytokine, is a multifunctional protein that is ubiquitously expressed in a variety of cells and tissues; however, enzymatic function of MIF still remains elusive in cells. In this study, we assessed details of the tautomerase activity of MIF. We established rapid purification condition for MIF by using pGEX system and compared the L-dopachrome tautomerase activity of GST-MIF, tMIF, and MIF. The results show that GST (glutathione S-transferase)-epitope tag or N-terminal amino acids flanking the essential $P^{2}$ almost completely abrogated L-dopachrome tautomerase activity of MIF. Subsequently, to determine whether the N-terminal tags have effects on oligomerization of MIF, protein cross-linking products were analyzed on $15\%$ SDS-PACE. The result demonstrates that N-terminal tags are dispensable for the formation of MIF's homooligomers. Thus, the results imply that exposure of If containing hydrophobic pocket in the active site is critical for L-dopachrome tautomerase activity of MIF. In addition, our study suggest that the MIF's tautomerase activity might be influenced by interacting with cellular partners.

물리치료과 학생들의 임상실습만족도에 관한 연구 : 일부지역을 중심으로

김상수,서현규,김병곤,이재홍,권원안,Kim, Sang-Soo,Seo, Hyun-Kyu,Kim, Byoung-Gon,Lee, Jae-Hong,Kwon, Won-An 대한고유수용성신경근촉진법학회 2012 PNF and Movement Vol.10 No.1

Purpose : This study was investigation of satisfaction in clinical practice of students in a college. Methods : 250 students were participated in this study for 8 weeks though getting results of clinical practice from 1, 2, 3 clinic hospitals. Results : This was for knowing about achievement, It could figure out the increasing achievement the higher satisfaction with education and environment for clinical practice of physical therapy. As a result, whole satisfactions for environment and course or education in clinical practice was higher. Conclusion : This research was not too much higher satisfaction on participated students in clinical practice. So, it needs to suggest to more study for increasing satisfaction on clinical practice.

체간신전근의 근력강화운동과 신장운동이 20대 청소년의 근력 및 유연성에 미치는 영향

김상수,이우형,송명수,Kim, Sang-Soo,Lee, Woo-Hyung,Song, Myung-Soo 대한고유수용성신경근촉진법학회 2010 PNF and Movement Vol.8 No.1

Purpose : This study aimed to examine the Influence of muscle strengthening exercise and stretching exercise of trunk extensor muscles on muscular strength and flexibility in adolescent of the twenties. Methods : Muscle strengthening exercise group(n=10), stretching exercise group(n=10) and strengthening and stretching exercise group(n=10) were measured muscular strength by digital back and leg dynamometer and flexibility by sit and reach test and trunk extension test at pre-intervention and post-intervention in 4weeks. Results : The flexibility 1, flexibility 2 and muscular strength of muscle strengthening exercise group were significantly increased within the intervention period(p<.05). The flexibility 2 and muscular strength of stretching exercise group were significantly increased within the intervention period(p<.05). but flexibility 1 was not significantly different at in 4 weeks(p>.05). The flexibility 1, flexibility 2 and muscular strength of muscle strengthening and stretching exercise group were significantly increased within the intervention period(p<.05). Conclusion : We were found that muscle strengthening exercise and stretching exercise of trunk extensor muscles could improve muscular strength and flexibility for adolescent of the twenties.

사회적지지가 베이비부머의 창업기회역량에 미치는 영향에 관한 연구: 창업자기효능감의 매개효과를 중심으로

김상수,임왕규,Kim, Sang Soo,Lim, Wang Kyu 한국벤처창업학회 2017 벤처창업연구 Vol.12 No.5

본 연구는 베이비부머 (1955-1963년생)를 대상으로 창업자기효능감을 매개 변수로 하여 사회적지지가 창업기회역량에 미치는 영향에 관하여 분석하였다. 창업정책과 교육은 청년창업사관학교 등의 제도를 통해 대부분 대학생 및 청장년층을 위주로 진행되고 있고, 또 이들을 대상으로 사회적지지나 제도적지원이 창업의지에 미치는 영향 등에 대한 연구는 활발히 진행되고 있는 반면, 베이비부머에 대한 연구는 복지부문에 치우치고 있고 실제로 이들은 은퇴 후 생계를 위해 치밀한 준비없이 생계형 창업에 뛰어들고 있으나, 이 베이비부머를 대상으로 한 사회적지지가 기회형 창업 추진에 필요한 창업기회역량에 미치는 영향에 관한 연구는 거의 없다시피 하다. 이에 본 연구는 사회적지지가 베이비부머의 창업기회역량에 미치는 영향을 알아보기 위해 주로 서울시와 경기도 일원에 거주하는 베이비붐 세대들로부터 수집한 설문지 387부를 실증 분석을 실시하였다. 분석 결과 첫째, 사회적지지가 창업기회역량의 기회인식과 기회평가 모두에 유의한 영향을 미치는 것으로 나타났다. 둘째, 사회적지지가 창업자기효능감에 미치는 영향에서는 정서적, 물질적 지지만 자신감에 유의한 영향을 미치고, 정서적지지와 평가적지지만 자기조절효능감에 유의한 영향을 미치고, 정서적지지와 물질적지지만이 과업도전감에 유의한 영향을 미치는 것으로 나타났다. 셋째, 창업자기효능감 중 자기조절효능감과 과업도전감 만이 창업기회인식에 유의한 영향을 미치는 것으로 나타났고, 자신감, 자기조절효능감 및 과업도전감 모두가 기회평가에 유의한 영향을 미치는 것으로 나타났다. 넷째, 사회적지지가 창업자기효능감을 매개하여 창업기회역량에 미치는 간접효과는 부분적으로 유의한 것으로 나타났다. This study analyzed the effects of social support on entrepreneurial opportunity competence for Baby boomer (born in 1955-1963), focusing on mediating effect of entrepreneurial self-efficacy. The governmental start-up policy and entrepreneurship education are mostly conducted for the college students and young generation mainly through such programs as the youth start-up school. In addition, studies on the effects of social support and institutional support on the entrepreneurial intention of young generation entrepreneurs are being actively pursued. Meanwhile, the study for baby boomers is on the welfare side mainly. Although they are starting to make their living-based business without prior careful preparation for their livelihood after retirement, while there is little study on the effect of social support for this baby boomer on entrepreneurial opportunity competence needed for opportunistic entrepreneurship. Therefore, in this study, in order to investigate the effect of social support on Baby boomer's entrepreneurial opportunity competence, an empirical analysis of the 387 questionnaires collected by the baby boomers living in Seoul and Gyeonggi provinces were conducted. As a result of analysis, First, Social support has a significant effect on both Opportunity recognition and Opportunity assessment of entrepreneurial opportunity competence. Second, In the effects of social support on self-efficacy were found to be significant in Emotional and Instrument support only on Self-confidence, In Emotional support and Feedback support only on Self-regulated efficacy & Emotional support and Instrument support only on Goal challenge were found to be a significant effect. Third, Self-regulated efficacy and Goal challenge in the Entrepreneurial self-efficacy on Entrepreneurial opportunity recognition were found to be a significant effect. All Self-confidence, Self-regulated efficacy & Goal challenge in the Entrepreneurial self-efficacy on Entrepreneurial opportunity assessment were found to be a significant effect. Fourth, Indirect effect of social support on entrepreneurial opportunity competence mediated by Entrepreneurial self-efficacy was found to be partially significant.

공황장애 환자의 질환행동에 관한 연구

김상수,제영묘,김상엽,이대수,이승호,최은영,Kim, Sang-Soo,Je, Young-Myo,Kim, Sang-Yeop,Lee, Dae-Soo,Lee, Sung-Ho,Choi, Eun-Young 한국정신신체의학회 1998 정신신체의학 Vol.6 No.2

This study was conducted to determine the important factors in the illness behavior of panic disorder patients. And then, find the best ways to lead the patients who have recurrent panic attacks to the adequate therapeutic situations. We studied 53 patients diagnosed as panic disorder according to DSM-IV among the outpatients who had been followed up at Bong Seng Memorial Hospital for 6 Ms, from May 1997 to October 1997. To evaluate the illness behaviors, we designed a checklist including socio-demographic data, degree of subjective distress from medical and psychiatric treatment, panic symptoms, life events, places of help-seeking, Anxiety Sensitivity Index. Using the checklist, we had semistructured interviews with the panic disorder patients to elucidate their help-seeking behaviors from first panic attack to diagnosing as panic disorder. The results were as follows ; 1) After first panic attack, the patients initially sought help at 1) Emergency room 40%, 2) Rest &/or Personal emergency care 35%, 3) Pharmacy 10%, 4) Outpatient care at hospital 10%, 5) Oriental medicine 5%. 2) Considering the panic symptoms, derealization, paresthesia and the severity of panic symptoms were the most important factors affecting the patient's help-seeking behaviors who had experienced the first panic attack. 3) Most of all the patients (80%) were apt to visit the hospitals within 15 days after experiencing about 3 panic attacks. 4) Before diagnosed as panic disorder, the patients had visited 3-5 health care centers during about 1 year. 5) Primary care physicaians(for example, emergency care physicians, family doctors and internists) had the most important roles in treating or guiding the patients to the adequate therapeutic situations. From the above results, the authors propose that non-psychiatric physicians have to know the panic disorder or attacks exactly. When patients complaint sudden onset physical symptoms e.g. palpitation, dyspnea, dizziness or the cognitive symptoms like the fear of death or insanity, physicians should consider the possibility of panic attack and encourage the patients to be evaluated for psychiatric illness.

중년 남환에서 다병소성(多病巢性) 골수염으로 오진된 Langerhans Cell Histiocytosis (LCH)의 치험례

김상수,박형식,윤현중,허진영,김진권,정재호,Kim, Sang-Soo,Park, Hyung-Sik,Yong, Hyun-Jung,Huh, Jin-Young,Kim, Jin-Kwon,Jung, Jae-Ho 대한악안면성형재건외과학회 1997 Maxillofacial Plastic Reconstructive Surgery Vol.19 No.1

Langerhans Cell Histiocytosis(Idiopathic Histiocytosis, Histiocytosis-X) is most often found in children and young adults, and cell proliferation with specific phenotype shows ultrastructural and immunohistochemical similarities with Langerhans Cells that normally exist in epithelium and mucosa. This disease occurs as single or multiple lesions in skull, ribs, vertebrae, mandible and long bones, and when it involves mandible, clinical sign and symptoms such as bone swelling and pain are noticed. When it involves alveolar bone, severe tooth mobility as well as gigival inflammation, proliferation, and ulceration are commonly found, and so it is not easy to differentiate it from general inflammatory diseases. Any local lesion at the tooth apex on the x-ray view needs to be differentiated from inflammatory disease, and multiple lesions from multiple ostoeoma and chronic multifocal osteomyelitis. This case is LCH in 51-year-old male patient ; this is a rare case, for the patient belongs to an age group with very low incidence rate of the disease. although three-timed biopsy tests and longterm observation at two university hospitals, it was misdiagnosed as multifocal osteomyelitis.

스케일간 웨이블릿 계수 절대치의 선형 모델링을 이용한 영상 보간

김상수,엄일규,김유신,Kim Sang-Soo,Eom Il-Kyu,Kim Yoo-Shin 대한전자공학회 2005 電子工學會論文誌-SP (Signal processing) Vol.42 No.6

웨이블릿 영역에서의 영상 보간은 웨이블릿 계수들의 통계적 특성과 스케일간 의존성을 표현하는 확률모델을 이용한다. 본 논문에서는 보간할 영상에 대해 스케일간 웨이블릿 계수의 절대치를 선형 모델링하여 분산을 추정하고 이를 바탕으로 고주파 부대역의 확률모델을 실현하여 영상을 보간하는 방법을 제안한다. 본 논문의 방법은 확률 모델에 대한 추정된 파라미터에 의해 웨이블릿 계수를 난수 형태로 발생시키는 방법을 사용한다. 확률모델을 따라 난수를 발생할 경우 추정 부대역에 난수에 의한 잡음이 발생하게 된다. 본 논문에서는 후처리 과정으로 Wiener filter를 사용하여 부대역의 잡음을 제거하였다. 제안 방법으로 외삽한 부대역에 대한 확률 밀도함수를 비교적 정확하게 추정한 것을 볼 수 있다. 실험을 통해 제안방법이 bicubic과 같은 전통적인 방법뿐 아니라 웨이블릿 영역에서의 다른 영상보간법보다 나은 주관적, 객관적 성능을 가지고 있음을 보였다. Image interpolation in the wavelet domain usually takes advantage of the probabilistic models for the intrascale statistics and the interscale dependency. In this paper, we adopt the linear model for the absolute values of wavelet coefficients of interpolated image across scale to estimate the variances of extrapolated bands. The proposed algorithm uses randomly generated wavelet coefficients based on the estimated parameters for probabilistic model. Random number generation according to the estimated probabilistic model may induce the 'salt and pepper' noise in subbands. We reduce the noise power by Wiener filtering. We observe that the proposed method generates the histogram of the subband coefficients similar to the that of original image. Experimental results show that our method outperforms the previous wavelet-domain interpolation method as well as the conventional bicubic method.