Using Automated Container Type Culture System Hericium erinaceum Mushroom Production Technology

Woo-Sik Jo1,Sung-Hak Lee,Min-Gu Kang,Who-Won Park 한국버섯학회 2016 버섯 Vol.20 No.2

Time, place, and the high-tech industry to overcome barriers to the fusion of the so-called "smart agriculture" is changing the landscape of agriculture. Precision Agriculture's core temperature, humidity, location information, and summary information in real time, all significant ICT controlling technique. The system is a four-season container production for the mushroom cultivation temperature, humidity, illumination, self-regulation, such as carbon dioxide, the optimal environment for mushroom cultivation was implemented. Hericium erinaceum (also called Lion's Mane Mushroom, Bearded Tooth Mushroom, or Bearded Tooth Fungus) is an edible mushroom and medicinal mushroom in the tooth fungus group. Native to North America, Europe and Asia it can be identified by its tendency to grow all the spines out from one group (rather than branches), long spines (greater than 1 cm length) and its appearance on hardwoods. About 40 days of incubation 1.5kg oak sawdust was used as the test medium bag. The humidity was maintained more than 85~95% and temperature was 18~20°C, and CO2 density was 500~1,000ppm. The days for primordium formation showed us 6~12 days. The amount of fruitbody production was 110~260g per bag. This technique to establish new community support program in conjunction with the international movement, domestic sales and exports are also planned.

The Results of Curative Radiotherapy for Carcinoma of Uterine Cervix

Ryu, Ryeong,Chang, Gee Young,Namkong, Sung Eun,Bahk, Yong Whee,Shinn, Kyung Sub,Kim, Seung Jo,Suh, Tae Suk,Yoon, Sei Chul,Kang, Ki Mun CATHOLIC MEDICAL CENTER 1994 Bulletin of the Clinical Research Institute Vol.22 No.2

One-hundred five patients with invasive carcinoma of the uterine cervix treated with curative radiotherapy from March 1983 through October 1989 at the Department of Therapeutic Radiology, Kang-Nam St. Mary's Hospital. Among them, 78 patients received radiotherapy alone and 42 patients treated with neoadjuvant chemotherapy followed by radiotherapy and 15 patients were lost to follow up. All patients had follow up from 2 to 106 months (median; 62 months). Age of the patients ranged from 32 to 79 years at presentation (median; 59 years). The overall 5-year survival rates was 50.8%, and the 5-year survival rates by stage ⅠB, ⅡA, ⅡB, ⅢA, ⅢB, ⅣA was 47.7%, 70.2%, 64.1%, 40.0%, 23.1%, 14.3%, respectively. The 5-year survival rates was noted 51.2% of radiotherapy alone and 50.4% of neoadjuvant chemotherapy followed by radiotherapy. The overall failure rate was 18.3% (22/120) including 11.7% (14/120) locoregional failure, 5.8% (7/120) distant metastasis and 0.8% (1/120) locoregional failure with distant metastasis. Treatment failure rates by the stages were 15% (3/20) in stage ⅠB, 10.5% (2/19) in stage ⅡA, 10.2% (5/49) in stage ⅡB, 20% (1/5) for stage ⅢA, 61.5% (8/13) in stage ⅢB, and 28.6% (4/14) in stage ⅣA. The overall complication rate was 34.2% (41/120), including wet desquamation 7.5% (9/120), diarrhea 6.7% (8/120), radiation proctitis 5.8% (7/120) in decreasing order. A multivariate analysis of factors influencing the survival showed patient age (P=0.0291), FIGO stage (P=0.0001), Karnofsky performance status (P=0.0043), initial hemoglobin level (P=0.0001), and intracavitary radiation (P=0.0004), but, no significancy in histology (P=0.29) and teatment method (P=0.87).

The Results of Curative Radiotherapy for Carcinoma of Uterine cervix

강기문,유미령,장지영,서태석,윤세철,박용휘,신경섭,남궁성은,김승조,Kang Ki Mun,Ryu Mi Ryeong,Chang Gee Young,Suh Tae Suk,Yoon Sei Chul,Bahk Yong Whee,Shinn Kyung Sub,Namkoong Sung Eun,Kim Seung Jo The Korean Society for Radiation Oncology 1993 Radiation Oncology Journal Vol.11 No.1

가톨릭의과대학 강남성모병원 치료방사선과에서 1983년 3월부터 1989년 10월까지 79개월 동안에 자궁경부암으로 근치적 방사선치료를 받았던 135명의 환자들 중에서 추적이 가능하였던 120명의 환자들을 대상으로 치료결과및 예후에 영향을 미치는 인자에 대하여 후향적 분석을 하였다. 방사선 단독으로 치료한 환자는 78명이었고 유도 화학요법을 방사선 치료전에 시행한 환자는 42명이었다. 대상 환자들의 추적 조사기간은,2개월에서 106개월이었고 중간 추적조사 기간은 62개월이었다. 환자들의 나이는 32세부터 79세까지의 분포를 보였다(중앙값, 59세). FIGO 병기별 분류에 의하면, IB 기가 20명 ($16.7{\%}$), IIA 기가 19명 ($15.8{\%}$), IIB기가 49명 ($40.8{\%}$), IIIA 기가 5명 ($4.2{\%}$), IIIB기가 13명 ($10.8{\%}$), IVA 기가 14명 ($11.7{\%}$)이었다. 전체환자의 5년 생존율은 $50.8{\%}$였다. 병기별 5년 생존율은 IB 기가 $47.7{\%}$ IIA 기가 $70.2{\%}$, IIB 기가 $64.1{\%}$, IIIA 기가 $40.0{\%}$, IIIB 기가 $23.1{\%}$, IVA 기가 $14.3{\%}$였다. 치료방법에 따른 5년 생존율은 방사선 단독으로 치료한 환자가 $51.2{\%}$였고, 유도화학요법을 방사선 치료전에 시행한 환자는 $54.0{\%}$였다. 치료후 재발은 22명 ($18.3{\%}$,)에서 관찰되었고, 이중 14명 ($11.7{\%}$)에서 국소재발이, 7명 ($5.8{\%}$)에서 원격전이가, 1명 ($0.8{\%}$)에서 국소재발과 원격전이가 함께 발생하였다. 그리고, 치료에 의한 합병증은 41명 ($34.2{\%}$)에서 관찰되었으며 9명 ($7.5{\%}$)에서 습낙설, 8명 ($7.5{\%}$)에서 설사, 7명 ($5.8{\%}$)에서 방사선 직장염의 순으로 발생하였다. 예후와 관련된 생존율에 영향을 주었던 인자로는 나이 (p<0.0291), 병기(p<0.0001), 전신상태(p<0.0041), 초기 혈색소 수치 (p<0.0001), 강내 조사(p<0.0004)였고, 조직학적 소견(p<0.29), 유도 화학요법과의 병행치료(p<0.87)는 통계학적으로 유의하지 않았다. This is a retrospective analysis of 135 patients with invasive carcinoma of the uterine cervix treated with curative radiotherapy from March 1983 through October 1989 at the Department of Therapeutic Radiology, Kang-Nam 51. Mary's Hospital. Among them, 78 patients received radiotherapy alone and 42 patients treated with neoadjuvant chemotherapy followed by radiotherapy and 15 patients were lost to follow up. All patients had follow up from 2 to 106 months (median; 62 months). Age of the patients ranged from 32 to 79 years at presentation (median; 59 years). According to FIGO classification, there were 20 ($16.7{\%}$) in stage IB, 19 ($15.8{\%}$) in stage IIA,49 ($40.8{\%}$) in stage IIB, 5 ($4.2{\%}$) in stage IIIA, 13 ($10.8{\%}$,) in stage IIIB,14 ($11.7{\%}$) in stage IVA. The pathological classification showed 96 ($80.0{\%}$) squamous cell carcinomas, 5 ($4.2{\%}$) adenocarcinomas and 19 ($15.8{\%}$) proven by cytology. The overall 5-year survival rates was $50.8{\%}$, and the 5-year survival rates by stage IB, IIA, IIB, IIIA, IIIB, IVA was $47.7{\%},\;70.2{\%},\;64.1{\%},\;40.0{\%},\;23.1{\%},\;14.3{\%}$, respectively. The 5-year survival rates was noted $51.2{\%}$ of radiotherapy alone and $50.4{\%}$of neoadjuvant chemotherapy followed by radiotherapy. The overall failure rate was $18.3{\%}$(22/120) including $11.7{\%}$ (14/120) locoregional failure, $5.8{\%}$ (7/120) distant metastasis and $0.8{\%}$(1/120) locoregional failure with distant metastasis. Treatment failure rates by the stages were $15{\%}$ (3/20) in stage IB. $10.5{\%}$ (2/19) in stage IIA, $10.2{\%}$, (5/49) in stage IIB, $20{\%}$ (1/5) in stage IIIA, $61.5{\%}$(8/13) in stage IIB, and $28.6{\%}$ (4/14) in stage IVA. The overall complication rate was $34.2{\%}$(41/120) including wet desquamation $7.5{\%}$, (9/120), diarrhea $6.7{\%}(8/120), radiation proctitis $5.8{\%}$(7/120) in decreasing order. A multivariate analysis of factors influencing the survival showed patient age (p < 0.0291), FIGO stage (p<0.0001), Karnofsky performance status (p<0.0043), initial hemoglobin level (p<0.0001), and intracavitary radiation (p<0.0004), but, no significancy in histology (p<0.29) and treatment method (p < 0.87).

급성 심근경색 후 심인성쇽의 발생에 관여하는 위험인자

전두수(Doo Soo Jeon),정해억(Hae Uk Chung),승기배(Ki Bae Seung),강동헌(Dong Hun Kang),김상우(Sang Wo Kim),김용주(Young Ju Kim),채장성(Jang Sung Chae),김재형(Jae Hyung Kim),홍순조(Soon Jo Hong),최규보(Kyu Bo Choi) 대한내과학회 1996 대한내과학회지 Vol.50 No.6

Objectives: Cardiogenic shock resulting from acute myocardial infarction is a serious complication with high mortality. The early identification of patients at high risk of developing post-infarction cardiogenic shock might allow early intervention in an attempt to prevent cardiogenic shock and to reduce the mortality due to cardiogenic shock. The aim of the present study was to examine the risk factors of inhospital development of cardiogenic shock among patients with acute myocardial infarction. Methods: We studied 152patients with acute myocardial infarction who were admitted to Kang-Nam St. Mary's hospital within 24hours after the onset of chest pain and did not have cardiogenic shack on admission between March 1991 and May 1994. Clinical data of these patients were analyzed. Results: Of 152patients, 17(11.1%) developed cardiogenic shock during their hospital stay. Cardiogenic shock developed in 53% of cases more than 24hours after admission. 82.4% of patients with cardiogenic shock died whereas a 6.7% in-hospital mortality was found among patients without cardiogenic shock. Multivariate regression analysis that controlled for variables affecting incidence of postinfarction cardiogenic shock showed that independent risk factors for in-hospital cardiogenic shock were history of myocardial infarction (adjusted relative odds[RO]=5.294, 95% confidence interval[CI]=2.149 to 13.041); heart failure on admission (RO=3.344, 95% CI=1.738 to 6.432); hyperglycemia (>180mg/dl) in non-diabetic patients (RO=3.270, 95% CI=1,590 to 6.727); age over 70 year old (RO=2.912, 95% CI= 1.816 to 4.668); ST deviation over 4mm (RO=2.417, 95% CI=1.225 to 4.767); peak LDH level greater than 1600U/ml (RO=1.154, 95% CI=1.080 to 1.233). Patients with one independent risk factor had an estimated probability of 10.5% for developing inhospital cardiogenic shock; patients with two independent risk factors, 48.5%, patients with three risk factors, 65.0% patients with four risk factors, 65.7% patients with five risk factors, 67.2%. Conclusion: Of post-infarction cardiogenic shock during admission, 53% developed more than 24hours after admission. The more independent risk factors on admission for inhospital cardiogenic shock patients with acute myocardial infarction had, the more likely in-hospital cardiogenic shock developed.

Safety u-System Design for Industrial Field

Sung-jo Yun,Tae-young Choi,Jin-Hyung Park,Sung-hun Kang,Sharly Joana Halder,Joon-goo Park 대한전자공학회 2008 ICEIC:International Conference on Electronics, Inf Vol.1 No.1

There are many dangerous elements in industrial field. Many works are exposed to the danger. Therefore, industrial field has need of disaster prevention system. In this paper, we propose a disaster prevention system for preventing accidents which can occur in industrial field. A disaster prevention system consists of monitoring system, sensing system and kiosk station and information terminal. Monitoring system manages an industrial field and it transmits information in the worker. Sensing system detects the disaster elements using temperature, flame, smoke, wind direction, wind velocity and infrared ray sensor. Kiosk station controls entrance admission to workplace. It provides field information to worker. Information terminal provides field information, worker location and facility records. To prevent accidents in industrial field, they support safety control strategy that provides overall information on various multi misfortune situations.

Emission Characteristics of High-Voltage Plasma Diode Cathode for Metal Surface Modification

Kang, Eun-Goo,Kim, Jin-Seok,Lee, Seok-Woo,Min, Byung-Kwon,Lee, Sang-Jo Korean Society for Precision Engineering 2015 International Journal of Precision Engineering and Vol.16 No.1

Electron beam cathodes have been used in various fields such as microscopy, X-ray tubes, welding, and surface modification. Generally, cathodes use metals with lower work function, higher thermal resistance, lower poisoning effects of gases, etc. <TEX>$LaB_6$</TEX>, tungsten, and tantalum have normally been used as cathode materials with special materials coated if required. This study investigated the high-voltage plasma diode cathode for surface modifications of metal products such as polishing, hardening and heat treatment. The most fascinating features of this cathode are the high voltage and current that can be obtained at a low vacuum of a few mTorr. However, it is difficult to control the emission current to attain a steady state and to obtain higher brightness than that achieved using a thermal cathode. We studied the emission characteristics in terms of cathode and anode design parameters such as anode distance and cathode shape. Additionally, changes of emission characteristics are discussed in terms of the type of gas, pressure parameter, etc. using the emission resistance, effective breakdown voltage, and brightness. Finally, by measuring the change in surface roughness using the emitted electron beams, we found that the surface roughness values before the process were <TEX>$Ra=0.8{\mu}m$</TEX> and <TEX>$Rz=5.4{\mu}m$</TEX>, whereas those after the process were <TEX>$Ra=0.25{\mu}m$</TEX> and <TEX>$Rz=2.3{\mu}m$</TEX>. The electron beam polishing technology is eco-friendly and can minimize the emission of many harmful materials that arise when existing mechanical or electrochemical polishing technologies are used.

Phosphate Doping into Monoclinic BiVO₄ for Enhanced Photoelectrochemical Water Oxidation Activity

Jo, Won Jun,Jang, Ji‐,Wook,Kong, Ki‐,jeong,Kang, Hyun Joon,Kim, Jae Young,Jun, Hwichan,Parmar, K. P. S.,Lee, Jae Sung WILEY‐VCH Verlag 2012 Angewandte Chemie Vol.124 No.13

<P><B>Ein monoklines BiVO</B><SUB><B>4</B></SUB><B>‐Gitter</B> wurde mit Phosphat dotiert, was die Aktivität in der photoelektrochemischen und photokatalytischen Wasseroxidation mit sichtbarem Licht gegenüber reinem BiVO<SUB>4</SUB> ungefähr um den Faktor 30 steigerte. Elektrochemische Impedanzspektroskopie und Dichtefunktionalrechnungen identifizieren einen deutlich verbesserten Ladungstransfer des BiVO<SUB>4</SUB> als den Hauptgrund für die verstärkte photoelektrochemische Aktivität.</P>

Microwave-assisted Synthesis of Highly Fluorescent and Biocompatible Silicon Nanoparticles Using Glucose as Dual Roles of Reducing Agents and Hydrophilic Ligands

Jo, Seongho,Ryu, Bowon,Chae, Ari,Choi, Yujin,Kang, Eun Bi,Nur aeni,,Park, Byoungnam,Park, Sung Young,In, Insik Chemical Society of Japan 2017 Chemistry letters Vol. No.

Effect of Ulmus davidiana Planch (Ulmaceae ) on T-lymphocyte-producing cytokines such as IL-2, IL-6, and IFN-γ production in collagen-induced arthritis of rats

Kang Han-Ju,Kim Kyung-ho,Jo Hyun-seog,Hwang Min-seob,Kim Kap-sung 대한침구의학회 2005 대한침구의학회지 Vol.28 No.3

유근피 약침액이 류마티스 관절염에 치료효과가 있는지 알아보기 위한 실험으로 Type Ⅱ Collagen으로 관절염을 유발시킨 쥐들을 이용하여 세포매개면역반응에 관여하는 T-cell에서 분비하는 싸이토카인의 농도를 측정하였다. 유근피는 항염증작용과 손상된 세포 및 골조직에 보호작용 등을 가진 것으로 알려져 있다. 수컷쥐들을 CⅡ로 감작시킨 후에 쥐들에게 식염수와 유근피약침을 주사하였다. 식염수를 주사한 대조군과 비교했을때, 유근피 약침을 주사한 군에서 Inguinal lymphnode cell의 IL-2,IL-6, IFN-γ를 생산하는 능력이 현저히 저하되었다. 감작후 14일 후에 세포를 채취하여 배양해서 관찰한 결과 7일동안 매일 한번씩 20㎍/100g의 Dose로 UDHA를 주사했을때 가장 효과가 좋았고 낮은 용량의 UD약침주사는 대조군과 큰 차이가 없었다. 결론적으로 쥐의 CIA의 치료와 관리에 효과적인 UD의 용량은 20㎍/100g 이상임을 알 수 있었다. 유근피 약침의 효과는 용량의존적으로 용량이 증가함에 따라 콜라겐 유발 관절염(CIA)을 억제하는 효과가 증가한다는 결론을 얻었다.

Expression of VEGF, p53, Apaf-1 and Caspase-9 in Head and Neck Squamous Cell Carcinoma

Sung Hak Lee(이성학),Yeo Ju Kang(강여주),Ui Ju Jo(조의주),Youn Soo Lee(이연수),Chang Suk Kang(강창석) 대한두경부종양학회 2012 대한두경부 종양학회지 Vol.28 No.2

배 경 편평상피암은 두경부의 악성종양 중 가장 흔하며, 임상적인 경과가 불량하다. 따라서 나쁜 예후를 가지는 환자군을 조기에 선별하여 더 적극적인 치료의 시행을 결정짓는 표지자의 필요성이 대두된다. 우리는 일련의 두경부 편평 세포암 검체에서 몇몇 분자 표지자의 예후적 유용성을 평가하고자 하였다. 방 법 23예의 두경부 편평세포암 검체를 대상으로 VEGF, p53, Apaf-1, caspase-9의 발현과 몇몇 임상병리학적 지표들간의 연관성을 면역조직화학염색을 통해 조사하였다. 결 과 환자군은 남성이 더 많았으며 평균연령은 63.7세였다. 1기가 5예, 2기가 2예, 3기가 8예, 4기가 8예였다. 평균생존기간은 37.3개월이었다. VEGF단백 발현은 종양의 크기와 통계적으로 유의한 연관성을 보였다. 이와 더불어 VEGF 단백 발현은 병기, 그리고 림프관 침습과 연관적인 경향성을 보였다. 그러나 VEGF단백 발현과 생존기간과는 관련성이 없었다. 또한, Apaf-1과 caspase-9의 단백발현은 다른 임상지표, 환자의 생존기간과는 관련이 없었다. 결 론 VEGF단백 발현은 두경부 편평세포암 환자에서 나쁜 임상경과를 예측할 수 있게 하는 표지자로서의 역할을 할 수 있다. 또한 본 연구는 두경부 편평세포암에서 별로 연구되지 않은 Apaf-1과 caspase-9의 발현상태를 밝힌 점에서 의의가 있다.