항암화학요법 관련 오심과 구토 완화를 위한 비약물요법에 관한 연구동향

소향숙,최자윤,조인숙,김영재,김지영,김애숙,김옥미,김춘심,김현오,설영애,안정옥,이애리,이영자 성인간호학회 2003 성인간호학회지 Vol.15 No.3

Purpose: Purposes of this study were to understand the current trends on complementary therapy in relieving chemotherapy-induced nausea and vomiting and to suggest the future research direction. Method: Subjects were selected on CINAHL, MEDLINE, Korean Academy Data Base from 1980 to 2001 which used nausea, vomiting, chemotherapy and complementary therapy as key words in experimental studies. Eight korean articles and twenty-one international articles were analyzed in terms of general characteristics, research methods, and types of complementary therapy. Data were analyzed by using descriptive statistical methods. Result: Since 2000, researchers have more actively used complementary therapy. In subject characteristics, mean age was 35.5 years old, 45% of the researchers were performed with high level of incidence of chemotherapy induced vomiting, 14% of them set limit of consecutive cycle during research, and 65% of them did not comment the selecting criteria of sample. About 60% of them were designed post-test only control group: 35% used INV by Rhodes, 31% used Likert scale, and 24% used VAS for dependent variable. Muscle relaxation therapy was mostly applied for relief of nausea and vomiting. Conclusion: Further studies will be needed to control extrinsic variables affecting nausea and vomiting in research design and to accumulate evidence with studies applying various complementary therapies.

병원가정간호사업 운영 현황 및 서비스 만족도에 관한 연구

홍춘실,오경옥,박미영,심희숙,차영남,Hong, Chun-Sil,Oh, Kyong-Ok,Park, Mi-Young,Sim, Hee-Sook,Cha, Young-Nam 한국가정간호학회 2001 가정간호학회지 Vol.8 No.2

The purpose of this study were to analyze the home care services and to evaluate the client's satisfaction with the home care services provided by home care service center in the C hospital. The data were collected by reviewing charts of 128 home care clients who were receiving home care services at C hospital from October 1997 to September 2000. The subjects for satisfaction of home care service were 20 clients from July 10 to September 30, 2000. The tool for measurement of present condition of home care service was developed by the researchers. The satisfactions of the home care services were measured by using the instrument developed by Im(997). The data were analyzed by using the SPSS/PC+. The results of this study were as followings : 1. Majority of the subjects was female(61.7%). The average of age was 63.5 years. The service has been used mostly by the elderly 60 years of age or older(71.1%). The economic level of most of subjects was in middle class(94.5%). 2. Majority of the subject had a cancer(55.4%), following stroke(25.0%). The average duration of disease for the subjects was 31 months. The average time of hospitalization for the subjects was 3.3 times. The duration of hospitalization was 10$\sim$30 days(26.6%), 30$\sim$60 days(23.4%) and above of the 210 days(9.4%). 3. Most of the subjects used his/her doctor (47.7%), as a consultant, following his/her nurse (28.1%), other patients or their family (21.9%). Most of reasons for a consultation were supportive management(Infusion or medication, 60.94%), following tube management(L-tube or T-tube, 25%), Foley catheter management (15.63%) etc. 4. 28 types of nursing diagnoses were used by the home care service. The nursing diagnosis altered nutrition: less than body requirement were used mostly by the home care service, following risk for infection, impaired skin integrity, impaired swallowing, ineffective airway clearance altered comfort: pain, impaired physical mobility. By the human-response pattern, exchanging(63.2%), moving(7.5%), feeling(10.4%), knowing(5.2%), communicating (2.6%), relating(0.5%) perceiving(0.4%) and choosing(0.3%). There were 42 nursing intervention types were performed by the home care service. By the NIC(nursing intervention classification. McCloskey. Bulech. 1996). physiologic: complex (30.3%) was the most, safety(28.3%), behavioral(20.0%), physiologic: basic(10.8%) and health system(1.7%). Observation or assessment was the most nursing intervention performed by the home care service. following IV infusion. vital sign observation. infusion management and fluid-electrolyte balance management. 5. The level of client's satisfaction with provided home care services showed considerably high(2.67/ 3).

여성노인의 자원봉사 참여 활성화에 관한 연구

심미영,정정숙,염동문 한국가정과학회 2004 한국가정과학회지 Vol.7 No.2

The purpose of this study was to examine the influential variables of participation toward voluntary activities of elderly women's. For this purpose, the data collected 312 women's elderly in Jinju city. Statistics employed for the analysis were frequencies, logit regression and multiple regression analysis. The major results of this study were as follows ; In participation intention toward voluntary activities for women's elderly, the variables which influence were job, state of health, level of life, need of voluntary activities, and satisfaction of voluntary activities in the past.

RAW 264.7 세포에서 silica에 의한 유리 라디칼 생성에 미치는 protein kinase 억제제의 영향

심상수,조남영,윤미연,이지윤,김창종 중앙대학교 약학연구소 2002 약학 논총 Vol.16 No.-

To investigate involvement of protein kinase in reactive oxygen species (ROS) and peroxynitrite (PON) generation, we examined effect of protein kinase inhibitors on silica-induced ROS and PON generation in RAW 264.7 cells. Silica dose-dependently increased ROS and PON generation. Protein kinase C inhibitor, bisindolmaleimide and RO32-0432, slightly inhibited silica-induced ROS generation and significantly inhibited PON generation. Tyrosine kinase inhibitor, erbstatin and DHC, significantly inhibited silica-induced ROS generation but not PON generation. Calmodulin antagonist (W-7), calmodulin-dependent protein kinase Ⅱ inhibitor (KN-62) and mitogen-activated protein kinase inhibitor (PD98059) significantly inhibited silica-induced PON generation but not ROS generation. These results suggest that protein kinase C appears to be involved in both ROS and PON generation, tyrosine kinase in ROS generation, and calmodulin antagonist and mitogen-activated protein kinase in PON generation induced by silica in RAW 264.7 cells.

B16 melanoma 세포에서 nitric oxide가 멜라닌 생성에 미치는 영향

심상수,조남영,윤미연,이지윤,김창종 중앙대학교 약학연구소 2002 약학 논총 Vol.16 No.-

To investigate the effects of nitric oxide and cGMP on melanin production, we measured the melanin production in B16 melanoma cells stimulated by alpha-melanocyte stimulating hormone (MSH). NO donor, such as, sodium nitroprusside (SNP), SIN-1, SNAP and L-arginine increased melanin production in basal state. SNAP potentiated melanin production by MSH, but other NO donors did not. In the study the potentiating effect of sodium nitroprusside on cAMP-dependent melanin production, sodium nitroprusside did not increase melanin production induced by MSH, forskolin and 8-Br-cAMP. Non-selective cAMP/cGMP phosphodiesterase inhibitor (IBMX) and selective cGMP phosphodiesterase inhibitor (zaprinast) significantly increased MSH-induced melanin production, whereas soluble guanylyl cyclase inhibitor (ODQ) inhibited MSH-induced melanin production. These results suggest the possibility that MSH-stimulated melanin production may be mediated via not only cAMP-dependent pathway but also cGMP-dependent pathway in B16 melanoma cells.

응급진료센터 과밀화와 특별관찰구역의 운영

심호식,장문준,하영록,정순미,이한식 大韓應急醫學會 1997 대한응급의학회지 Vol.8 No.1

Overcrowding of emergency departments is a growing problem. Delays in admitting patients to inpatient units have been reported as a contributing factor to overcrowding. Overcrowding in ED results in many patients not receiving needed care and impairs the ability of the ED provider to meet the needs of those patients that are treated. The effect of the critically ill patients on the overcrowded emergency department make emergency physicians frustrated. So we created the 'special unit for observation' of critically ill patients and managed them continuously and closely. The special unit for observation have 4 physical beds and monitors and 2 ventilators. One nurse and senior ED residents were asigned to the management of the patients in the special unit. 160 patients(3.4% of all ED visits) admitted to special unit during the period of March 1, 1996 to May 31, 1996. we could continue assessment and management of critically ill patients without psychologic strain or burnout generated by overcrowding. We think that special unit for critically ill patients is a very effective alternative to overcrowded ED.

도시 가계의 여가오락서비스 소비지출구조 및 영향요인분석

김영숙,심미영 한국가정과학회 2004 한국가정과학회지 Vol.7 No.1

The purpose of this study was to examine the consumption expenditure structure for leisure & recreational service in urban households. For these purpose, the data collected 175 households in Pusan metropolitan city. Statistics employed for the analysis were frequencies, means, one-day ANOVA, and multiple regression analysis. The major results of this study were as follows; Average monthly expenditure for leisure, recreational service was 190,342 won. And their expenditure for leisure & recreational service share was 12.89 % of total expenditure. Those expenditure with high income elasticity were hobby & culture education, and journey. And those with low income elasticity were play & inspection, and health & sports. In leisure & recreational service expenditure, the variables which influence were job and degree of household head, and income.

소비자 충동구매행동 유형화에 관한 연구 : 마케팅 자극변인, 소비자 탐색적 활동변인 및 심리적 변인을 중심으로

김영숙,심미영 경성대학교 2001 論文集 Vol.22 No.1

The purpose of this study is to analyze factors of consumer's impulsive purchase behavior, classify such behavior into several types and then and determine what effects such parameters as demography, marketing stimulus, exploratory activity and psychology have on each type of impulsive purchase behavior. Results of the study can be summarized as follows. First, the factor analysis showed that factors of consumer's impulsive purchase behavior could be classified into seven, or negative mood, perceived product attitude, image identification, outside recommendation, non-intention, taste relation and positive mood. These seven factors were found accounting for 66.56% of consumer's impulsive purchase behavior. Second, the group analysis for the typical classification of consumer's impulsive purchase behavior showed that such impulsive consumers could be classified into six groups, or non-impulsive purchase, non-intention, product relation and perceived attribute, positive mood, outside recommendation, negative mood and image identification groups. Third, parameters influencing types of consumer's impulsive purchase behavior were analyzed to give the following findings. (1) The non-impulsive purchase group was negatively affected by allowance level, product packing, and innovatory quality. The group was lower in allowance level and innovatory quality than the other groups and less considered product packing. (2) The non-intention group thought product quality less important than in the other groups. The group also sought few information. For the group, self-control decreased non-intention impulsive purchase while materialism orientation increased impulsive purchase behavior. (3) The group of product relation and perceived attribute did impulsive purchase behavior more frequently when they were at lower grade. The group was also found considering price discount important. For the group, interpersonal communication influenced negatively while innovatory Quality had static effects. (4) The positive mood group was more affected by product packing and interpersonal communication in making purchase decisions. (5) The outside recommendation group was statically influenced by product packing, price discount and information seeking. Under the consideration of product packing and price discount, the group purchased products more impulsively as it sought more information. (6) The group of negative mood and image identification showed more impulsive purchase behaviors when they were higher in age and allowance levels. For the group, product packing, brand change, and risk taking were statically influential while self-control had negative effects.

대학생의 환경의식적 구매태도와 행동의 인과관계분석 : 환경의식적 변인과 소비자정보 변인을 중심으로 Focused on Environmental Awareness Variables and Consumer Information Variables

김영숙,심미영 慶星大學校 1998 論文集 Vol.19 No.2

The purpose of this study was to investigate causal relations on the environmental awareness purchase attitude and behavior of consumer. The findings were as follows; 1. The knowledge of Environmental problems, environmental awareness and satisfaction of using in green product had significant difference according to sex. And neutral information had significant difference according to sex and age. 2. The environmental awareness purchase attitude had significant difference according to sex and age. And the environmental awareness purchase behaviors had significant difference according to sex. 3. The correlations among the environmental awareness purchase attitude, cognition of environmental mark, concerns of environmental problems, knowledge of environmental problems, environmental awareness experience of green products and satisfaction of using in green products were very high positively. And the correlations among the environmental awareness purchase behavior, cognition of environmental mark, concerns of environmental problems, knowledge of environmental problems, commercial information, personal information, neutral information and satisfaction of using in green products were very high positively. 4. In analysis of causal effect on the environmental awareness purchase attitude and behavior, sex, cognition of environmental mark, concerns of environmental problems, knowledge of environmental problems, environmental awareness, satisfaction of using in green products, personal information, neutral information and environmental awareness purchase attitude had effect on the environmental awareness purchase behavior of consumer directly and indirectly.

발관리 교육프로그램이 노인 당뇨병 환자의 발관리 이행과 족부합병증에 미치는 효과

노영숙,전시자,권연숙,임미숙,심강희 노인간호학회 2007 노인간호학회지 Vol.9 No.2

Purpose : Diabetic foot complications are significant problems in diabetes mellitus and often result in lower extremity amputation. This study was conducted to verify the effects of foot care education on compliance with foot care and diabetic foot complications when the patient is an elder with diabetes. Method: A group pretest-posttest design was used to examine the effects of 6 months of foot care education with a group of 13 elders with diabetes. The major dependent variables including foot care compliance and diabetic foot complications were measured at the beginning and end of the treatment period to examine the effects of foot care education. Result : There were no significant differences in total foot care compliance scores and presence of diabetic foot complication after 6 months, Conclusion : Interventions involving problem based education and pursuing long-time effects may be more effective in implementing and sustaining improvements than just group education or one time interventions for elders with diabetes.