척추경 나사못을 이용한 척추 유합술에서 고정범위에 따른 인접 추간판의 압축 거동 분석

안면환,안종철,이수호,정일섭,이춘열,이장우 영남대학교 의과대학 2003 Yeungnam University Journal of Medicine Vol.20 No.2

요추부 척추에 기구를 시술한 유한요소 복합체 모델을 이용하여 제 4-5 요추간판에 대한 해석을 수행한 결과, 근육의 작용을 케이블과 케이블 가이드로써 단순화 모사한 follower 하중에서 수직하중인 경우보다 높은 압축력을 나타내어 더욱 안정함을 보였고 불안정성의 원인이 되는 전단력과 굽힘모멘트의 발생은 미미하였다. 장분절 고정에 의한 인접 분절에 전단력이 증가됨을 실험적으로 보였는데, 이는 장분절 고정이 퇴행성 변화 촉진에 기여할 것으로 추정된다. Background: Confirm the stability of intervertebral disc sustaining each fused lumbar spine cases, comparing vertical compression, A-P shear force and rotational moment on intervertebral disc of instrumented lumbar spine with simple vertical compression load and follower load using finite element analysis. Materials and Methods: We analyze the stability of intervertebral disc L4-5 supporting fused lumbar spine segments. After performing finite element modelling about L1-L5 lumbar vertebral column and L1-L4 each fusion level pedicle screw system for fused lumbar spine fine element model. Intervertebral discs with complex structure and mechanical properties was modeled using spring element that compensate stiffness and tube-to-tube contact element was employed to give follower load. Performing geometrical non-linear analysis. Results: The differences of intervertebral disc L4-5 behavior under the follower compression load in comparision with vertical compression load are as follows. Conclusion: As a result of finite element interpretation of interpretation of instrumented lumbar spine, the stability of L4-5 sustaining fused lumbar segment, the long level fused lumbar spine observed hing stability under follower load. This research method can be the basis tool of effects prediction for instrumentation, a invention of a more precious finite element interpretation model which consider the role of muscle around the spine is loaded.

동종 골수 이식한 백혈병에서 단반복 유전자로 살펴본 혼합 키메라 현상의 의의

장대영,이정신,서철원,이규형,이제환,지현숙,박찬정,한면수,최동원,김정균,최성준,김성배,김상위,김우건,김상희 대한조혈모세포이식학회 1998 대한조혈모세포이식학회지 Vol.3 No.1

연구배경 : 동종 골수 이식한 백혈병에서 키메라 현상의 분석은 착상, 질병 재발과 이식 거부를 이해하는데 도움을 줄 수 있다. 최근 STR을 PCR로 증폭한 검사법에 의해 매우 민감하고 유용하게 혼합 키메라 현상을 검출할 수 있다고 보고되고 있으나, 이 방법의 민감도와 임상적 의의는 아직 완전히 정립되지는 않았다. 따라서 PCR-STR검사법이 혼합 키메라 현상을 민감하게 검출하는지 보고, 동종 골수 이식 후 혼합 키메라 현상의 변화 양상을 관찰하고, 키메라 현상의 임상적 의의를 보고자 하였다. 방법 : 형제로부터 동종 골수 이식한 급성 백혈병 6명과 만성 백혈병 2명의 모두 8명을 대상으로 하였다. 44개 골수 검체에서 phenol/chloroform방법에 의하여 단핵세포 DNA를 추출하였다. DNA는 CTT 삼중체, vWA와 amelogenin시발체를 이용하여 증폭하였다. 증폭 산물은 5% 폴리아크랄아미드 젤에서 전기영동 뒤 은 염색으로 확인하였다. 2명의 DNA를 여러 비율로 혼합하여 상기 검사를 하여 검출 가능 최소 농도를 결정하였다. 결과 : 상기 검사법의 검출 가능 최소농도는 0.25%였다. 혼합 키메라 현상은 8명중 4명에서 관찰되었다. 혼합 키메라 현상은 보인 1명에서 급성 및 만성 이식편대 숙주 질환이 나타났고, 완전 공여자 키메라 현상을 보인 1명에서 만성 이식편 대 숙주 질환이 나타났다. 점진적으로 증가하는 혼합 키메라 현상을 보인 2명은 이식 후 12개월에 질병 재발을 보였으나, 완전 공여자 키메라 현상을 보인 경우엔 재발이 관찰되지 않았다. 결론 : PCR-STR검사법은 동종 골수 이식 후 남아 있는 환자 세포를 검출하고 키메라 현상을 관찰하는데 유용한 방법이다. 또한 이 검사법은 동종 골수 이식 후 재발의 조기 진단, 이식편 대 숙주 질환의 평가와 면역 관용에 임상적으로 응용할 수 있으리라 생각한다. Background : Chimerism analysis after allogeneic bone marrow transplantation (BMT) for leukemia could be helpful understanding of the early marrow engraftment, disease relapse, and graft rejection. Recently, a PCR technique which amplifies short tandem repeats(STR) has been reported to be highly sensitive and reliable in detecting mixed chimerism. But its sensitivity and clinical significance has not been established. The purpose of this study was firstly, to confirm whether a PCR-STR in highly sensitive enough ti assess mixed chimerism, secondly to monitor the changing patterns of mixed chimerism after allogeneic BMT, and lastly to determine correlation between the chimeric status and the clinical outcome. Methods : A study was made eight patients (six with acute leukemia and two with chronic leukemia) who underwent unmanipulated allogeneic BMT along with matched donors. DNA was extracted from mononuclear cells of 44 bone marrow samples using a phenol/chloroform method. Amplification of DNA was done using CSFIPO-TPOX-TH01(CTT) triplex with or without vWA or amelogenin primer. The amplified product was separated on 5% polyacrylamide gel and was confirmed by silver staining. The sensitivity of CTT triplex method was determined by mixing DNA from two person in serial proportion using the same method. Results : The sensitivity for CTT triplex method was 0.25% Mixed chimerism was documented in 4 of 8 patients. ONe of four patients with mixed chimerism developed acute and chronic graft versus host disease (GVHD) and one of four patients with complete donor chimerism also developed chronic GVHD. Two patient with progressive mixed chimerism relapsed at 12 months post-BMT, whereas no patient with complete donor chimerism has relapsed. Conclusion : The study has found that PCR-STR was an effective method for the detecting residual host cell and monitoring the chimeric status after allogenic BMT. PCR-STR can also be clinically applicable in early prediction of relapse, appropriate assessment of GVHD, as well as tolerance after allogeneic BMT.

동일한 시료에 대한 국내 기관간의 STR 분석결과 비교 : STR 유전자좌 분석법의 표준화 설정을 위하여

박종태,신경진,양윤석,우광만,이숭덕,이승환,이정빈,정연보,조승희,한길로,한면수,홍승범 大韓法醫學會 2001 대한법의학회지 Vol.25 No.1

This paper described a collaborative exercise intended to see what kinds of short tandem repeat (STR) loci are used in different DNA typing laboratories in Korea and to compare their results for the demonstration whether uniformity of DNA profiling results from different laboratory could be achieved in Korea Laboratories were asked to test five tissue DNAs using methods routinely used in each laboratory and to report the results to the coordinating laboratory. The exercise demonstrated that each laboratory was using different STR loci for the typing with different STR numbers,2 VNTRS,36 STRs and amelogenin in total, and the direct comparison of the results from all the laboratory for the 18 loci could not be done as only one laboratory submitted typing results. Among 21 loci for which several laboratories submitted typing results, results for 14 loci were the same and results for the other 7 loci were different depending on the participating laboratory. D1S80, F13A01, D16S539, D21S11, D18S51, D3S1744 were the loci with different typing results. Even in the cases where commercial kits were used, the results were not the same depending on the machines used, that is the capillary electrophoresis or the gel based electrophoresis. The reason for the different results, points about the standardization of the methods arid the profiling data were described.

이데오로기의 社會化과정에 대한 연구 : 유교이념의 사회화 과정을 중심으로 Centering on the process of confucianism's Socialization

李冕鎬 湖南大學校 1985 호남대학교 학술논문집 Vol.5 No.-

While Ideology as false conciousness executes negative function to distorted and disguise the Social reality, it also exercises positive function to present us to the Valuable directions of life and Society, to show us a idea 1, to integrate our Society, to Concentrate on potentialities of the members, and to streng then one body feeling of self-identification. However, the process which Such a Kind of ideology becomes Socialized is very similiar to that of Confucianism. Namely, Socielization of Idelogy takes the process of Social education which interalizes and mistificates Social role playing, existing order, and inculcation of idea System, or actual perspective to ward the world. Therefore, the purpose of the study lies in extracting generalization of the Socialization process.

體育敎育의 哲學的 基礎에 關한 硏究

이면영 德成女子大學校 1982 德成女大論文集 Vol.11 No.-

體育系列 學生들의 特性에 關한 調査硏究 : 體育系列 他系列 中心으로

李면榮 德成女子大學校 1988 德成女大論文集 Vol.17 No.-

韓國과 美國 體育敎育의 比較硏究 : 大學 體育敎育課程을 中心으로

이면영 德成女子大學校 1985 德成女大論文集 Vol.14 No.-

This study is related with the physical education curriculum in Korean and American college. Theoretical subjects and practical subjects are classified into required subjects and elective subjects. After analyzing and contrasting required subjects and elective subjects, the result could be summed up as follows. 1. Theoretical subjects average 63.4 hours and 72.7 grades in Korean college, and they average 48.5 hours and 65.4 grades in American college. 2. Practical subjects average 36.6 hours and 27.3 grades in Korean college, and they average 51.5 hours and 34.6 grades in American college. 3. Theoretical required subjects average 67.9 hours and 76.1 grades in Korean college, and they average 91.5 hours and 95.6 grades in American college. 4. Theoretical elective subjects average 60.7 hours and 70.6 grades in Korean college, and they average 89.3 hours and 94.3 grades in American college. 5. practical required subject average 32.1 hours and 23.9 grades in Korean college, and they average 8.5 hours and 4.4 grades in American college. 6. Practical elective subjects average 39.3 hours and 29.4 grades in Korean college, and they average 10.7 hours and 5.7 grades in American college. 7. Theorectical subjects which are most enforced in Korean college are the psychology of the physical education, the management of the physical education, and the principle of the physical education. In American college, they are kinesilogy, the administrationof the physical education and organization, and the recreation organization. 8. Practical subjects which are most enforced in Korean college are atheletics and swimming. In American college, they are atheletics and basket ball. 9. Theorectical required subject which is most enforced in Korean college is the principles of the physical education, and it is and introduction to the physical education. Practical required subject which is most enforced in Korean college is atheletics, and it is basket ball in American college. 10. Theoretical elective subject which is most enforced in Korean college is the sociology of the physical education, and it is the administration of the physical education or organization in American college. 11. Korean and American college have no clear classification of required and elective subjects, and each college has differences in selection of subjects.

作業場에서의 有機溶劑 濃度에 關한 硏究

李泳昊,金冕燮 漢陽大學校 環境科學硏究所 1991 環境科學論文集 Vol.12 No.-

본 연구에서는 유기용제를 다량 사용하는 작업에서 발생되는 공기중의 유기용제의 복합농도를 측정하여 작업장별 혼합용제의 허용농도 초과율에 관한 실태조사 및 근로자의 폭로 정도를 파악하였다. 방향족 탄화수소류(Aromatic hydrocatbons)는 60%로 거의 대부분을 차지하고 있으며, 케톤류(Ketones)는 전체의 28%, 부타논류(Butanone)는 12%로 나타났다. 산업안전보건법상의 특정 유기용제 종류별 성분의 검출에서 본 대상 부서별 도장에서 사용되는 유기용제는 제 2 종 및 제 3 종 유기용제를 혼합하여 사용하고 있음을 알 수 있었다. 총 50개 작업장, 공기중 혼합용제별 허용농도 초과율은 대형트럭부서의 초과율은 40%, 소형트럭 부서의 초과율은 33%, 중형승용하 부서의 초과율은 33%, 소형승용차 부서의 초과율은 20%, 그리고 기타 부서에서의 초과율은 12%로 각각 나타났다. A study was performed in order to measure the mixed organic solvent concentrations in air of workplaces during December 12∼29, 1989. The mixed organic solvent concentration was analyzed by the gas chromatography. The results were as follows; The detection rate of organic solvents was the highest in case of aromatic hydrocarbones 60%, ketones 28%, and butanones 12%, respectively. The detection rates of organic solvents by component category was the higest in case of the 2nd class solvents and the 3rd class solvents. Among the total of 50 workplaces, the detection rate of organic solvents was the higest in case of large truck workplace 40%, small truck and middle passenger workplaces 33%, small truck workplace 20%, and other workplace 12%, respectively.

Tennis.Soccer.Volley Ball의 有酸素的 作業强度에 關한 硏究

李面榮 德成女子大學校 1984 德成女大論文集 Vol.13 No.-

The aerobic work intensity and the rating of perceived exertion were examined in three different physical activities used five healthy male subjects. Storke of tennis, inside kick of soccer, and over hand pass of volley ball were used as experimental exercises in this study. The subjects performed these exercises on the spot or transfering their body from side to side. The results were summarized as follows: 1) The significant relinear relationships were observed between heart rate and oxygen uptake in all exercises except for stroke of tennis on the spot. 2) At a given oxygen uptake a higher heart rate was obtained in exercises on the spot than when exercises were performed transfering the body from side to side. 3) In the exercises on the sport only 30∼40% of their maximal aerobic capacities were required. However, in the activities transfering the body from side to side more than 80% of maximal aerobic capacity were required at maximal frequencies. These results suggested that an important factor determining work intensity in ball game might be transces of the body in playing. 4) Between the rating of perceived exertion and physiological variables, the relinear relationship was observed. Consequently, the rating of perceived exertion seems to be effective indicator of training intensity.

Freud 와 Skinner의 인간성 진단에 관한 비교연구

李冕鎬 호남대학교 1988 호남대학교 학술논문집 Vol.9 No.-

1. The core of Freud's theory lies in that Id of the unconsciousness controls life instinct of human beings. The term Id consists of Eros which is representing both sexual pleservation of man's life and Thanatos which is distructive and aggressive death instincts, Human behavior thus governed by this two instincts in its root. This theory of Id coined by Freud got some criticism as an theory that could be abused as a material for the defence in social discipline, governing and suppressing the society. However, Freud insists that the social value of the repression and the satisfaction should be accepted and more over, agued that not only the suppression of the human instinctive desire but also the fullfillment of it could lead as to civilisation. After all to emphasize the realm of unconsciousness where Libido is active in the depths of the mind, it minimizing the reason into a trifle one. Thus in this article, it is examined that whether the Freud's theory of unconsciousness that is Id could justify minimizing the reason and the oppression of society. 2. Behaviorism proposed by Skinner means that the liberty of human behavior is denied and could be controled by the contingency of environment. Therefore behaviorism stipulate the man as a mechanical Robot on the premise that human being are passive and dependent existence. These view resulted from the fact that man give up self-administration and give over to environment the control which has been in his power to exercise: individual is only a prism and a passive piece of sculpture without subjecthood. So according to behaviorism human being is considered as the same with animal. Thus man is not free as if it is a machine: also should be mechanical and influenced by determinism. It ignore the activity innate human being and rejected the view which interpretes behavior as a result of human mind and spirit. Therefore Behaviorism is a sort of determinism which declares that human behavior dicided by a certain cause and the cause is a lways external; in short, it is causationism. conclusionaly behaviorism only interested in importance of culture and society, and more interested in environment; it expect that man's environment should be transformed into humanistic one and it considers the role of the human genetic endowment as nothing. However, surely man has his own self control and autonomy with it he can rule the environment, therefore, man behaves with his own determination and desire; there lies a limitation of the theory of behaviorism.