구개부에 발생한 다형성선종의 치험례

이창진,김태열,김효언,김희광,전인성,윤규호 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.2

Pleomorphic adenoma is the most common of all salivary gland tumors, constituting over 50 per cent of all cases of tumors, and approximately 90 per cent of all benign salivary gland tumors. Since the term mixed tumor' was introduced by Broca for its dual origin of epithelial and mesenchymal elements, the term plemorphic adenoma suggested by Willis characterizes closely the unusual histologic pattern of the lesion. The parotid gland is the most common site but it may occur in any of the salivary glands. It is somewhat more frequent in women and in the fourth to sixth decades, but they are also relatively common in young adult and have been known to occur in children. Treatment of choice is surgical excision. Adequate surgery with safe margin reduce its recurrence rate. We represent a case of pleomorphic adenoma with literature review in 65-year old male occured in the palate. The lesion was successfully treated by surgical excision.

사람폐암세포주 (PC-14)에서 Cyclosporin A에 의한 Adriamycin 내성의 극복

김영환,홍원선,송재관,강윤구,이진오,강태웅,김건열,한용철 대한내과학회 1990 대한내과학회지 Vol.38 No.3

Cyclosporin A and verapamil were tested using MTT assay to evalute the modification effect on the resistance to adriamycin in a human lung cancer cell line(PC-14) and its resistant subline(PC-14/A). PC-14/A was derived by the continuous exposure of PC-14 to incremental concentrations of adriamycin. PC-14/A was 2.5 times more resistant to adriamycin in terms of ICso than PC-14. Cyclosporin A alone, at a concentration of 2.5㎍/㎖, inhibited the growth of PC-14 to 68.3%. 2.5㎍/ ㎖ and 5.0㎍/㎖ of cyclosporin A showed an increase in the cytotoxicity of adriamycin (p<0.01) with 5.0㎍/㎖ being greater than 2.5㎍/㎖(p<0.01). Excluding the direct cytotoxic effect, however, cyclosporin A did not increase in the sensitivity of PC-14 to adriamycin but only showed an additional cytotoxic effect with adriamycin. Verapamil (up to 6.0㎍/㎖) did not inhibit the growth of PC-14. 3.0㎍/㎖ of verapamil did not increase the cytotoxic effect of adriamycin. The combination of cyclosporin A and verapamil with adriamycin enhanced the cytotoxicity of adriamycin, but the result was similar to that of cyclosporin A with adriamycin. 5.0㎍/㎖ of cyclosporin A modified the adriamycin resistance of PC-14/A(SR, 3.2). However, 3.0㎍/㎖ of verapamil did not significantly reverse the adriamycin resistance of PC-14/A. The modified effect of the combination of 5.0㎍/㎖ of cyclosporin A and 3.0㎍/㎖ of verapamil was similar to that of 5.0㎍/㎖ of cyclosporin A alone in PC-14/A. These results demonstrate that cyclosporin A has an additional cytotoxic effect with adriamycin in PC-14 and PC-14/A and has overcome the acquired resistance to adriamycin in PC-14/A. They also suggest that cyclospoin A may have the therapeutic potential in the treatment of human lung cancer.

악교정 수술과 심미성

김태열,윤규호,전인성,고성준 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

There are so many reasons why patient selects orthodontic and orthognathic treatment, but most of them want functional improvement. Sometimes patients are not satisfied though functionally improved. It is apparent that they want esthetic improvement too. Satisfaction and happiness are influenced by on self-evaluation, emotional state, expectation and so on. Clinicians have difficulty in estimating and treating the patients by psychological norm. Therefore, we study the relation between orthognathic surgery and aesthetics.

ZnO 박막 센서의 DMA 가스 검지 특성

김성우,최우창,류지열,박성현,최혁환,이명교,권태하 경북대학교 센서기술연구소 1997 센서技術學術大會論文集 Vol.8 No.1

The DMA(Dimethylamine) gas sensors were fabricated with the ZnO-based thin films grown by a RF magnetron sputtering method. We investigated the sensitivity and response time according to temperature variation and DMA gas concentration. The ZnO-based thin film sensors sputtered in oxygen atmosphere showed higher sensitivity than those sputtered in argon atmosphere. The ZnO-based thin film sensors doped with Al_(2)O_(3), In_(2)O_(3) and V_(2)O_(5) and sputtered in oxygen atmosphere showed the maximum sensitivity of 218(working temperature, 250 ℃, DMA gas, 160 ppm) and speedy response time. The ZnO-based thin film sensors doped with Al_(2)O_(3), In_(2)O_(3), TiO_(2) and V_(2)O_(5), sputtered in oxygen atmosphere and aged at 330 ℃ showed the maximum sensitivity of 156(working temperature, 250 ℃, DMA gas, 160 ppm).

大邱市內 綜合病院 醫務記錄部署 職員의 醫務記錄業務에 대한 態度

김태열,박재용 慶山大學校 保健福祉硏究所 1999 保健福祉硏究 Vol.3 No.-

대구시내 종합병원의 의무기록부서 직원의 일반적 특성 및 의무기록업무에 관한 필요도를 분석하여 의무기록 관리 방법의 개선을 위한 기초자료로 제시하고자 1997년 6월 2일부터 6월 30일까지 대구시 소재 14개 종합병원에 근무하는 의무기록부서 직원 164명을 대상으로 설문조사 하였다. 본 연구대상병원의 의무기록부서 직원은 총 188명인데 의무 기록사수가 61명으로 32.4%였는데 대학병원이 27.3%로 일반종합병원의 36.5%보다 더 낮았다. 그리고 100병상당 의무기록사수는 평균 11명으로 대학병원이 0.7명, 일반종합병원이 1.5명이었고, 100병상당 의무기록부서 직원수는 평균 3.2명으로 대학병원이 2.5명, 일반종합병원이 3.9명이었다. 의무기록부서 직원은 여자가 81.1%였고, 연령은 20∼29세가 66.5%로 가장 많았다. 경력은 5∼10년 미만이 48.1%로 가장 높았으며, 학력은 전문대졸이 60.4%였다. 대체적으로 대학병원의 의무기록부서 직원이 일반종합병원보다 연령이 많고, 경력이 더 많았다. 그리고 면허소지별 주된 담당업무는 대체적으로 의무기록사가 본연의 업무에 더 종사하였다. 의무기록 전산 프로그램의 항목별 필요도는 분실차트 관리 82.9%, 차트추적관리 77.4%, 접수순서확인 75.6%, 미비기록관리 73.8%, 예약자 관리 71.3%순이었고 환자색인 48.2%, 의사색인 40.2%으로 비교적으로 낮게 나타났다. 대학병원의 의무기록사의 65.0%가 환자색인업우의 전산화가 필요하다고 하였으나 비의무기록사는 22.0%만이 필요하다고 하였고 의사색인업무의 전산화 또한 의무기록사는 60.0%, 비의무기록사는 12.0%가 필요하다고 하여 유의한 차이를 보였고, 질병, 수술색인 및 차트 추적 관리업무의 전산프로그램에도 의무기록사와 비의무기록사간의 유의한 차이를 보였다. 일반종합병원의 면허소지별 의무기록 전산프로그램 항목별 필요도는 의무기록사의 73.7%가 환자색인 업무의 전산화가 필요하다고 하였으나 비의무기록사는 48.2%만이 필요하다고 하였고, 미비기록 관리업무의 전산화 또한 의무기록사는 81.6%가, 비의무기록사는 62.5%가 필요하다고 하여 유의한 차이를 보였다. 의무기록업무의 표준화 항목별 필요도는 의무기록 서식의 표준화가 45.7%, 진료통계작성 기준시간 표준화가 45.7%, 통계일보 표준화가 39.0%, 통계연보 표준화 34.8%순이었고 대학병원의 의무기록사의 60.0%가 통계일보의 표준화가 필요하다고 하였으나 비의무기로사는 16.0%만이 필요하다고 하였고, 통계연보 표준화 또한 의무기록사는 50.0%, 비의무기록사는 24.0%가 필요하다고 하여 유의한 차이를 보였다. 일반 종합병원의 의무기록 표준화 항목별 필요도는 의무기록사의 65.8%가 의무기록서식의 표준화가 필요하다고 하였으나 비의무기록사는 41.1%만이 필요하다고 하여, 의무기록사와 비의무기록사간의 유의한 차이를 보였다. 차트보관장비 도입의 항목별 필요도는 비활용차트의 광화일시스템 도입이 78.0%로 가장 높았고, 이동식서가 도입이 73.2%, 비활용차트의 마이크로필름 도입은 31.1%로 비교적 필요도가 낮았다. 면허소지, 병원유형 여부에 따른 차트 보관 장비 도입에 유의한 차이가 있는 항목은 없었다. 질병분류 항목별 필요도는 질병분류시 1권(KCD-1권)확인의 필요도가 65.2%로 가장 높았고 보험청구시 의무기록부서에서 부여하는 코드번호 사용의 필요도 64.0%, 의사의 진단명 기재시 한글사용의 필요도 62.2%순으로 나타났다. 대학병원의 의무기록사의 85.0%가 의사의 진단명 기재시 한글사용이 필요하다고 하였으나, 비의무기록사는 56.0%만이 필요하다고 하였고 한국질병분류 1권(KCD-1권) 사용 또한 의무기록사는 90.0%, 비의무기록사는 58.0%가 필요하다고 하여 유의한 차이를 보였다. 이상의 결과로 볼 때 효율적으로 의무기록을 관리하기 위해서는 전산프로그램 기술개발과 의무기록 서식과 연보의 표준화로 업무의 능률을 올리고 날로 증가하는 차트로 인해 공간부족을 해결하기 위해서는 표준화로 업무의 능률을 올리고 날로 증가하는 차트로 인해 공간부족을 해결하기 위해서는 비활용차트의 광화일시스템 도입이 검토되어야 하고, 무엇보다도 의무기록의 중요성을 최고경영자의 새로운 인식과 의무기록사의 인력확보가 선행되어야 할 것이다. Questionnaire was administered from June 2 to June 31, 1997 to the 188 medical record personnel employed at the general and university hospitals in Taegu City. In order to survey on the opinions about the need of computer programs, microfilm and standardization for more efficient medical record management. The major findings are as follows: The average number of Medical Record Officer(MRO) were 1.1 per 100 beds, proportion of MRO among record personnel was 32.4%. Most of the medical record personnel was females(81.1%), 20∼29 years of age group(66.5%) and had experience of 6∼10years. The university hospital and more experienced as well as older aged personnel than the general hospitals. About half(48.2%) of the respondents was reported the need for computer program in managing with patient index. Most(70.7%) of the MRO expressed. the need for the computer program while 35.8% of non-MRO did. The need for doctor index in MRO was 62.1% and 28.3% in non MRO. The need for disease and operation index was reported in 60.4% of MRO while it was expressed in only 34.0% of non MRO. The need for the standardization of statistical daily census of medical record was reported in 39.0% overall. It was reported in 55.2% of MRO, but only 30.2% of non-MRO. The need for the statistical annual report was reported in 34.8% overall. Most of the respondents(73.2%) expressed the need for moblic rack. The need for microfilm was reported in 31.1% overall; the percentage was 39.4% in FRO while 20.0% in non-FRO. The translation of final diagnosis into Korean was advocated in most of the respondents(62.2%) and the use of ICD-CM in 47.0% overall; the percentage of approval was 58.6% in MRO while 40.6% in non-MRO.

가토에서 흡수성 차폐막 Biomech®의 골재생 효과

김태훈,유선열 전남대학교 치의학연구소 2001 구강과학 Vol.13 No.3

The purpose of the present study was to investigate the effect of absorbable membrane (BioMesh®) on bone regeneration in the rabbit by evaluating biodegradability, biocompatibility and bone regenerative capacity. Eight rabbits, weighing about 2kg, were used. Two bone defects, 8 mm in diameter and 7 mm in depth, were made. In the experimental group, the bone defect was covered with BioMesh® absorbable membrane. In the control group, induced spontaneous healing. The rabbits were sacrificed at 2, 4, 6, and 8 weeks after the operation. Radiographic and microscopic examination were performed. Results obtained were as follows: After 2 weeks, proliferation of the fibrous tissue was observed in the control group, but the newly formed cartilage and more active bone formation were noted in the experimental group. After 4 weeks, the new bone formation appeared in the control group, and in the experimental group, the bone trabeculi were densely aligned and matured. After 6 weeks, complete resorption of the BioMesh® membrane occurred in the experimental group. Both experimental and control group acquired dense osseous coverage, after 8 weeks. These results suggest that the BioMesh® absorbable membrane contributes new bone formation by guiding bone regeneration in the early stage.

관절염 모델에서 침형 경피신경 자극의 효과

김계엽,김태열,김경윤 東新大學校 2003 論文集 Vol.13 No.-

The purpose of this study was to investigate and analyze effect of needle transcutaneous electrical nerve stimulation with the change of immunohistochemistry method through the change of c-fos in spinal dorsal horn(pre, 4, 8, 12 and 24h). An experimental arthritis induced in 100 Sprauge-Dawley rats with a mixture 3% carrageenan and 3% kaolin(0.1 ㎖ in sterile saline) into the joint cavity of one knee. Each group was randomly divided into four groups; Group Ⅰ : control group, Group Ⅱ : arthritic limb-induced group, Group Ⅲ : Needle TENS application on ipsilateral arthritic limb(2 Hz, 200 μs, 20 min) group, Group IV : Needle TENS application on contralateral arthritic limb(2 Hz, 200 μs, 20 min) group. The results of this study were as follows: 1. In naked eyes opinion, c-fos immunoreactive positive neurons are increased markedly 4 hours after arthritis limb-induced in Rexed Ⅰ, Ⅱ of superficial dorsal horn. Group Ⅲ and group Ⅳ are more decreased than Group Ⅱ at 8 hours after arthritis limb-induced. 2. The c-fos immunoreactive positive neurons after application needle like transcutaneous electrical nerve stimulation on arthritic limb-induced model group are more decreased than only arthritic limb-induced group. 3. The number of c-fos immunoreactive positive neurons in superficial dorsal horn was decreased markedly 4 hours after arthritis limb-induced. Group Ⅲ and group N are more decreased than Group Ⅱ at 8 hours after arthritis limb-induced(p<0.001). Specially Group Ⅲ showed the most significantly effect at 8 hours(p<0.01). The above results suggest that needle transcutaneous electrical nerve stimulation effectively reduced in arthritic limb-induced model. In addition, greatly decreased the number of c-fos neurons explains needle transcutaneous electrical nerve stimulation application on ipsilateral arthritic limb is more effective than that on contralateral arthritic limb.

골격성 Ⅲ급 부정교합 환자에서 하악골상행지 시상분할골절절단술후 상순과 하순의 연조직 변화에 관한 연구

박관수,김태열,김희광,정정권,윤규호,전인성 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.6

Purpose : The prediction of profile change as a result of orthognathic surgery remains a problem during preoperative planning because of the difference relative movements of the hard and soft tissues. This study was performed to predict the changes o( upper and lower lips after BSSRO with non-rigid fixation Material and Methods : 15 patients wish skeletal Class III malocclusion treated by bilateral sagittal split ramus osteotomy(BSSRO) and mandibular setback were selected for analysis. Cephalometric data of presurgery and postsurgery 12 months were used. Wilcoxon signed rank test, calculation of Spearmans correlation rho and simple regression analysis were performed to predict the relations between hard tissue changes and soft tissue changes. Results : The horizontal change of hard tissue Pogonion and those of lower lips showed high correlation and the ratios were from 71% to 84%. The horizontal change of hard tissue Pogonion and those of chin showed high correlation and the ratios were from 90% to 92%. The horizontal change of hard tissue Pogonion and those of upper lips showed moderate correlation and the ratios were from 7% to 18%. Conclusion : This study suggests that the changes of lower lips are highly affected by the hard tissue change of mandible and those of upper lips are moderately affected. In comparison with other studies, no significant differences were found among the fixation methods.

ZnO 박막 센서의 암모니아 가스 검지 특성

최우창,김성우,류지열,박성현,최혁환,이명교,권태하 경북대학교 센서기술연구소 1997 센서技術學術大會論文集 Vol.8 No.1

The ammonia gas sensors were fabricated with the ZnO-based thin films grown by a RF magnetron sputtering method. We investigated the sensitivity and response time according to temperature variation and ammonia gas concentration. The sensors sputtered in oxygen atmosphere showed higher sensitivity than those sputtered in argon atmosphere. The Au(0.3 wt.%) doped-ZnO thin film sensors aged at 330 ℃ showed the maximum sensitivity of 28 and good response time at a working temperature of 250 ℃ and to 160 ppm ammonia gas. The Pt(0.1 wt.%) doped-ZnO thin film sensors showed the maximum sensitivity at a low working temperature of 200 ℃.

크리에이티브 요소를 통한 계층적 광고효과 모델에 관한 실증 연구

문달주,전성률,김태원 한국방송광고공사 2004 광고연구 Vol.0 No.64

본 연구는 목표 소비자에게 브랜드 가치를 증진시킬 수 있는 효과적인 광고를 집행하기 위해 실질적으로 광고제작에 도움이 될 수 있도록 하기 위한 목적으로 광고의 크리에이티브 평가요소들의 성과가 광고태도와 광고를 통한 구매관심도에 어떻게 영향을 미치는지 알아보고자 수행되었다. 이를 위해 기존 연구를 바탕으로 구조모형 기반 아래 광고 크리에이티브 제 요소 중 가장 주요한 요소인 메시지, 모델, 크리에이티브 구성 요소 각각의 전반적인 평가를 근거로 모델 파워, 메시지 파워, 크리에이티브 파워를 산출하고 이를 크리에이티브 성과 요소로서 독립변인으로 선별하였다. 세부적으로는 모델 파워를 구성하는 요인으로 선험연구의 이론적 근거를 가지고 모델의 적합성, 매력성, 신뢰성을 두고, 메시지 파워는 메시지의 이해성, 설득성, 독특성, 크리에이티브 파워는 독창성, 정교성을 두었다. 이는 크리에이티브 요소 각각의 부분적 성과가 크리에이티브 요소의 전반적 평가에 미치는 영향성과 다시 크리에이티브 전반적 평가가 광고 평가(광고 태도, 광고를 통한 구매관심도)에 미치는 영향성을 단계적으로 고찰해보기 위함이다. 본 연구의 의의는 기존에 산발적이고 단편적으로 이루어지던 것을 보다 통합적으로 공분산 구조모형이라는 체계적인 틀 안에서 단계적인 영향성을 검증해 본 것이라 하겠다. 연구모델 분석결과 실제로 특정 크리에이티브 요소에 따라 계층적으로 광고효과의 영향성이 달라지는 것을 검증하였다. 특히 모든 제품군에서 크리에이티브 파워가 광고태도에 가장 큰 영향을 미치는 크리에이티브 요소인 것으로 밝혀졌다. The importance of creating effective advertisements which can be helpful to improve brand value is ever increasing. The purpose of this study is to investigate effect of creative factor(message factor, model factor, creative/execution factor) in order to help creating advertisements. This study hierarchically analyzed the structural model about the effects of ad creative factors on advertisement attitude and purchase interest through advertisement. Message factor is constructed of understanding, persuasiveness, and uniqueness. Model factor is composed of credibility, attractiveness, and fit. Creative/execution factor is composed of novelty and elaboration & synthesis. Based on this concept, we made construct on 2 step Hierarchical Advertising Effectiveness Model(specific creative factor → overall creative power → ad effect). This Model has been developed in an effort to transcend varied limitations of other previous studies. Consequently, the practical value of this model is highly expected. The major findings from this model are summarized as follower: All of the three creative factors is hierarchically influenced on Ad Power(advertisement attitude and purchase interest) in every product class. Creative/execution is the most influential creative factor in this study. Theoretical and marketing implications, limitation and direction for future research are discussed.