방사선조사와 Paclitaxel의 병합요법에 의한 신내막 과증식억제

장기육,승기배,강동헌,임상현,정해억,임효영,김태균,김연실,채장성,김재형,홍순조,윤세철,최규보 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.6

내경동맥 지배 영역의 급성 허혈성 뇌졸중 환자에서 초 선택적 국소적 Urokinase주입술

김인규,김명규,김재규,조기현,김세종 대한신경과학회 1998 대한신경과학회지 Vol.16 No.5

멧누에 난각유전자의 구조해석 및 진화관계 연구

김기세,성승현,김순정,서동상 성균관대학교 생명공학연구소 1999 生命工學硏究 Vol.5 No.1

The chorion protein (A, B, C, D, E, HcA, HcB) are synthesized by monolayer of follicular epitherial cells and assembled after secretion into eggshell in B. mori. The chorion gene contains 15-multigene families (the pair-HcA, HcB) which are divergently oriented gene pairs in B. mori. The chorion protein of B. mandarina (Korean wild silkmoth) apparently differ those of B. mori in the structure, morphology and protein secondary structure. The chorion gene of B. mandarina have few been studied yet. We've studied the chorion gene of B. mandarina, constructed wild silkmoth genomic library and obtained the 10 Hc clones. 8 clones are sequenced and characterized (some are partial sequence). The sequence similarities of B. mori and B. mandarina of each families are 90% and 85% respectively. Some of them are changed the charge of amino acids in the terminal of central domain. The variable region of C-arm is composed of Cys-Gly, Cys-Gly-Gly repeated structure which determines the length variation in B. mandarina.. It means the genetic exchanges are occurred in the region among multigene families. We could find the structural and evolutionary relationship.

내시경적 역행성 췌담관조영술중 췌선방 조영 후 발생한 중증 췌장염 1예

장세중,기승석,김훈일,신혜영,박장원,송은훈,태재웅 朝鮮大學校 附設 醫學硏究所 2008 The Medical Journal of Chosun University Vol.33 No.2

내시경적 역행성 담췌관조영술 후 발생한 급성췌장염의 발생인자로 여러 가지 인자들이 관여하지만 특히 담췌관조영술 시행 후 과도한 췌선방 조영화에 의한 중증의 췌장염 증례를 경험하였기에 보고하는 바이다 Endoscopic retrograde cholangiopancreatography (ERCP) has been considered as a valuable tool for the diagnosis and management of disease of the pancreas and biliary tree. Post-ERCP pancreatitis is the most frequent and clinically significant complication following ERCP. But a few complication associated with this procedure are unforeseeable. Specially, acinarization as a result of a careless cooperation between operator and assistant may be influenced in complications of ERCP. Severe post-ERCP pancreatitis is rare complication, and its prognosis will be poor. Therefore, careful process and good relationship between operator and assistant in ERCP may be prevented this complication, but is not clear. Neglect of acinarization may be resulted in more aggravation of pancreatitis. We have cared for one patient with severe post-ERCP pancreatitis with pseudocyst after water-soluble contrast media spreading into the acini (acinarization) via ERCP in resolving phase idiopathic pancreatitis.

알칼리형 연료전지에서의 산소극 제조

문세기,김형진,공성호,조장호,김영채 한양대학교 에너지·환경기술연구소 1997 에너지·環境技術論文集 Vol.3 No.-

알칼리형 연료전지(Alkaline fuel Cell, 이하 AFC)의 산소극에 사용되는 촉매를 은 염의 화학적 환원법으로 제조하였다. 그리고 최적의 전극 제조 조건을 찾기 위해 촉매의 loading량, 전극 소결 온도, PTFE함량 및 촉매 입자 크기 등이 전극의 분극특성에 미치는 영향들이 조사되었다. 연구결과에 의하면, 최적 조건은 전극 소결 온도 350℃, PTFE 함량 9wt%, 촉매의 입자크기 68㎛ 이하이었다. 한편 촉매 loading량이 증가함에 따라 전극 성능이 향상되었다. 최적의 제조 조건에서 제작된 전극은 개회로 전위 1.11V(vs. RHE),200㎷ 분극(전극전위 0.91V vs. RHE)시 전류밀도 약 0.4A/㎠,300㎷ 분극 (전극전위 0.81V vs. RHE)시 전류밀도 1.0A/㎠의 성능을 나타내었다. Doped silver catalyst used for oxygen electrode in alkaline fuel cells was prepared by reduction method of silver salt. And the effects of the silver catalyst loading, electrode sintering temperature, content of PTFE and particle size of the catalyst on the polarization characteristics of the oxygen electrodes were investigated to find the optimum preparation conditions of the electrodes. According to the results of this work, the optimum conditions were sintering temperature of 350℃, PTFE content of 9 wt% and below catalyst particle size of 68 ㎛. On the other hand, with increasing the catalyst loading, the electrode performance was improved. The electrode prepared at the optimum conditions showed open circuit potential of 1.11V(vs.RHE), current density of 0.4A/㎠ at a overpotential of 200㎷ and 1.0A/㎠ at a overpotential of 300㎷.

정상인과 정신지체인의 치아우식증과 치아우식 원인균, 타액내 면역항체의 비교

최세원,양규호,최남기,강미선,임회순,오종석,김선미 대한소아치과학회 2007 大韓小兒齒科學會誌 Vol.34 No.3

탄광부 진폐증의 운동지수

조영선,김세곤,문우기,유재인,정치경 가톨릭대학 산업의학 센타 산업의학연구소 1984 韓國의 産業醫學 Vol.23 No.3

Exercise index(EI) was measured on 933 pneumoconiosis patients (865 patients with small rounded opacities and 68 patients with large opacities) and 176 suspected pneumoconiosis patients from Korean anthracitic mines, in order to evaluate the ventilatory impairment of pulmonary function according to the chest radiographic findings of pneumoconiosis. Exercise index was obtained from the maximum breathing capacity (MBC) and the exercise ventilation volume(EV) which were measured by spirometer and two step-test. Classification of pneumoconiosis was based on the international classification of ILO U/C. The results were as follows: 1. The mean value of E1 was significantly increased in pneumoconiosis patients with large opacities(46.0%) than in patients with small rounded opacities(26.5%) and with suspected pneumoconiosis(25.0%). The number of jpatients in substandard EI was 97.1% in patients with large opacities but 49.4% in patients with small rounded opacities and 40.3% in patients with suspected pneumoconiosis. 2. The mean values of EI and the number of patients in substandard EI were markedly increased in pneumoconiosis patients with small rounded opacities and suspected over 50 years of age. However, the number of patients in substandard EI showed no association with age in pneumoconiosis patients with large opacitis. 3. In pneumoconiosis patients with small rounded opacities, the mean values of EI and the number of patients in substandard EI showed significant association with the profusion (category) but no significant association with the type of small rounded opacities. 4. In pneumoconiosis patients with large opacities, the mean values of EI and the number of patients in substandard EI showed no significant difference between patients complicated with and without pulmonary tuberculosis. 5. No significant association of EI and the number of patients in substandard EI with the size of large opacities was observed in pneumoconiosis patients with large opacities, however, the mean values of EI showed increasing tendenccy in category B and C compared to category A.

흡연에 의한 급성 호산구성 폐렴 2예

박종빈,김학렬,주현준,유태양,신성남,신정현,송정섭,황기은,김소영,양세훈,정은택 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.2

최근 흡연을 시작한 젊은 성언에서 급성 호산구성 폐렴의 발생에 대한 증례가 보고되고 있다. 급성 호산구성 폐렴은 대개 발열을 동반하기 때문에 초기에는 감염성 폐렴으로 잘못 진단, 치료되는 경우가 많다. 아직 정확한 병태 생리 및 조직학적 소견은 밝혀져 있지 않지만 병력 청취 및 임상 양상, 방사선 소견의 관찰을 통해 급성 호산구성 폐렴을 의심하고, 진단을 위해 기관지 폐포 세척액 검사를 시행한다면 좀 더 쉽게 진단 내릴 수 있을 것이다. 본 저자들은 최근 처음 시작한 흡연에 의해 발생한 급성 호산구성 폐렴을 진단하고, 스테로이드를 투여하여 성공적으로 치료한 환자 2예를 경험하였기에 이를 문헌 고찰과 함께 보고하는 바이다. Acute eosinophilic pneumonia(AEP) is characterized by acute febrile respiratory illness associated with diffuse pulmonary infiltration and pulmonary eosinophilia. The specific etiology for acute eosinophilic pneumonia is elusive. By some investigators, cigarette smoking is suggested as a causative substance which can cause AEP. In recent, the authors experienced two cases of AEP following cigarette smoking. Both cases had characteristic features including age around 20 years, new onset smoking before occurance of AEP, diffuse infiltration on chest radiography, pulmonary eosinophilia based on bronchoalveolar lavage and acute improvement after steroid therapy. These clinical features are resemble with previous smoking induced AEP case reports. Base on these clinical features, cigarette smoking associated AEP could be diagnosed more easily.

Polyethylene glycol 용액(Colyte^(R))을 복용한 후 발생한 Boerhaave 증후군 1예

이관행,기승석,김인숙,김민정,박인호,장세중,하지수,김응수 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

Spontaneous esophageal rupture (Boerhaave's syndrome) is a rare case that require early diagnosis and treatment because of its high mortality. The oral administration of osmotically balanced polyethylene-glycol-based electrolyte preparation is a commonly prescribed preparation for cleansing in patients undergoing colonoscopy. Nausea, vomiting and abdominal pain are frequently seen, but serious adverse reactions are rare. Esophageal rupture secondary to severe vomiting, which occurred during colonoscopy preparation using polyethylene gIycoI(PEG) electrolyte solution is extremely rare and only few cases have been published in the literature. We report a case of spontaneous esophageal rupture after routine administration of the PEG before colonoscopy. 대장 정결을목적으로 PEG 사용 후 아주 드물게 발생하는 Boerhaave 증후군 1예를 경험하였기에 보고하는 바이다.

MgO에 담지된 촉매에서의 메탄의 짝지움 반응에 관한 연구

박종걸,김영채,문세기 한양대학교 에너지·환경기술연구소 1997 에너지·環境技術論文集 Vol.3 No.-

연속 흐름식 상압 반응기에서 메탄과 산소를 반응물로 하고 MgO,CaO,γ-Al₂O₃담체에 활성물질인 Li₂CO₃를 담지하여 제조한 촉매를 사용하여 반응 조건을 변화시키면서 메탄의 oxidative coupling 반응을 행하였다. Li₂CO₃담지시 활성이 크게 향상되었으며 MgO, CaO에는 9㏖%,γ-Al₂O₃에는 17㏖%를 담지 하였을 때 수율이 가장 좋았으며, 활성은 MgO>CaO>γ-Al₂O₃순으로 나타났다. Li₂CO₃(9㏖%)/MgO, CaO 촉매에서 최적 반응 조건은 온도 1030K P(CH₄)/P(O₂)=1, 접촉시간(W/F)은 0.0067g-cat.min/㎖였다. In the plug-flow at atmospheric reactor, the oxidative coupling of methane was performed with methane and oxygen using the catalysts prepared by impregnation of MgO, CaO,γ-Al₂O₃with Li₂CO₃in the various reaction conditions. The activity was enhanced at impregnation Li₂CO₃. The yield was utmost at 9㏖% in MgO, CaO and 17㏖% in γ-Al₂O₃. The activity was in order of MgO, CaO,γ-Al₂O₃. The optimum reaction condition was 1030K, P(CH₄)/P(O₂)=1, and 0.0067g-cat.min/㎖ in Li₂CO₃(9㏖%)/MgO,CaO catalyst.