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비정형 향정신병약물을 투여 중인 정신분열병 환자의 주관적 삶의 질 : 정신병리, 약물 부작용 및 약물에 대한 주관적 반응과의 관련성
김종훈,윤정희,이자영,노경희,홍성극,윤세창,강웅구,김용식 大韓神經精神醫學會 2003 신경정신의학 Vol.42 No.2
Objectives : The purpose of this study was to evaluate the characteristics of psychopathology, adverse drug effects, and Subjective response to drugs that have a significant impact on the subjective quality of life in schizophrenic patients receiving atypical antipsychotics. Methods : One hundred and one schizophrenic patients, who were receiving maintenance treatment with atypical antipsychotics, were evaluated. Subjective quality of life was assessed using the standardized Korean modification of a self-rating scale to measure subjective well-being under neuroleptics (KmSWN). Patients' psychopathology was evaluated using the Positive and Negative Syndrome Scale. Adverse effects and subjective response to drug were evaluated using the Liverpool University Neuroleptic Side Effect Rating Scale and the Drug Attitude Inventory-10, respectively. Correlation analysis and stepwise multiple regression analysis were conducted. Results : In psychopathology, the severity of depression and anxiety showed the most significant correlation with the score ofKmSWN. In adverse drug effects, the severity of psychic side effect and extrapyramidal side effect showed the most significant correlation with the score ofKmSWN. Regarding subjective response to drug, significant correlation was observed between the severity of subjective negative response and the score of KmSWN. Stepwise multiple regression analysis revealed that psychic side effect, extrapyramidal side effect, and depression contributed significantly to the total score of KmSWN. These variables accounted for 59.7% of the total variance. Conclusion : The results of the present study suggest that psychic side effect, extrapyramidal side effect and depressive symptom are the clinical characteristics that are significantly associated with the subjective quality of life. An effective management strategy for these variables should be established in developing a treatment program to enhance the quality of life of patients with schizophrenia.
가막사리(Bidens tripartita L.)와 미국가막사리(Bidens frondosa L.) 종자의 발아에 미치는 몇가지 요인
신혜정,신종섭,김지훈,김학윤,이인중,신동현,김길웅 경북대학교 농업과학기술연구소 1999 慶北大農學誌 Vol.17 No.-
The experiments were conducted to determine the factors such as light and darkness, phytohormone and seed coat, influencing on seed germination of Bidens tripartita L. and B. frondosa. The seeds of both species were germinated when seed coat was damaged and weakened GA3 and BA stimulated germination of both species but ABA and IAA had no effect on germination of them, which ranged 50.0% to 80.0%. In B. forndosa, when inner layer of seed coat was removed, germination was highly promoted up to 96.7% compared with 10.0% germination rate in another treatments.
투명단열 축열벽 시스템을 적용한 주거용 건물의 냉난방에너지 성능분석
김병수,김재웅,윤종호 대한건축학회 2004 대한건축학회논문집 Vol.20 No.7
In previous study, Overheating/heating performance was carried out through Test-cell measurement used by TI-wall(Transparent Insulation) system and Mass-wall system and the optimum composition of TI-wall system was proposed by simulation analysis in the Korean weather condition. The aim of this study was to analysis the Heating/cooling performance following the optimum composition of TI-wall used in residential building. The process of this study is as follows:1) The ESP-r simulation program was used in energy performance analysis and the reference model of residential building was made up to analysis energy performance on Ti-wall and Mall-wall system. 2) Standard weather file of seoul, Taejon, pusan and Cheju was made that was the format of simulation program(ESP-r). 3) The regional Heating/cooling energy performance was carried pit by suing regional standard weather file of TI-wall and Mass-wall system in residential building and the reduction of Heating/cooling energy with the change of wall size of per system was analyzed. 4) The energy reduction of TI-wall system of foreign country was compared with that of Korean. Consequently, when TI-wall is equipped with South Surface of Residential Building, annual Heating Energy of Building was cut down at the average of 79.1kwh/m²(Seoul:101.7kwh/m², Taejon:59.8kwh/m², pusan:99.5kwh/m², cheju:79.5kwh/m²) or 18% of total heating energy, Cooling energy increased the average of 15.15kWh/m², in the case of using Solar Shading Device and Air ventilation system, the cooling energy is not only increased by Ti-wall at the lever of 97%, the basic cooling energy is but also cut down about 6%.
이주연,이무석,윤진상,양종철,문지웅,정해원,은성종 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.6
Objectives : The purpose of this study was to investigate the stress coping strategies and psychological charactehstics, such as combined psychopathology and tendency of symptom interpretation, in patients with somatization disorder. Methods : Thirty patients meeting the criteria of DSM-IV somatization disorder were compared with thirty controls. We evaluated the subjects using Symptom Checklist-90-Revised (SCL-90-R), Somato-Sensory Amplification Scale (SSAS), Symptom Interpretation Questionnaire (SIQ), and The Ways of Stress Coping Questionnaire (SCQ). Independent t-test and Pearson correlation analysis were used. Results : From the results of SCL-90-R subscales, the scores of somatization, obsession-compulsion, depression, anxiety, and psychoticism were significantly higher in patients with somatization disorder than nonnal controls. Somatization disorder patients had greater amplification of physical sensation in SSAS and significantly higher score in physical interpretation of SIQ compared with psychological or environmental interpretation, In the SCQ of somatization disorder patients, we observed generallylower levels of total coping scores than the control group and significant positive correlation between passive coping style of SCQ and psychological interpretation of SIQ. Conclusion : These results show that patients with somatization disorder have various psychopathology, greater amplification of physical sensation, physical interpretation tendency of symptoms, and insufficient copying strategy.
연구보문 : 자연과학 ; 자포니카 벼의 종자 저장단백질 유전자 구조 및 발현분석 연구 현황
윤웅한 ( Ung Han Yoon ),이정화 ( Jeong Hwa Lee ),이강섭 ( Gang Seob Lee ),김영미 ( Young Mi Kim ),한장호 ( Jang Ho Hahn ),지현소 ( Hyeon So Ji ),윤성원 ( Sung Won Yoon ),이종렬 ( Jong Yeol Lee ),김태호 ( Tae Ho Kim ) 한국국제농업개발학회 2012 韓國國際農業開發學會誌 Vol.24 No.3
Based on the outcome of the rice genome sequencing, a lot of researches for identification of genes underlying useful traits and their utilization are being carried out recently. Especially, rice seed storage proteins are used as a main nutrition source for human while they are used as the nitrogen source for plant growth during seed germination. Rice seed storage proteins are divided by solubility in solvent into weak acid and alkali soluble glutelin, alcohol soluble prolamin, and salt soluble globulin. The rice genome contains 11 glutelin genes and 33 prolamin genes. In the case of prolamin genes, 15 genes are located in 15 Mb region on the chromosome 5. Clustering of seed storage protein genes on the same chromosomal region indicates that they are evolved from the same chromosome or they share similar gene expression regulatory region. Only single globulin gene existed on the chromosome 5. As a result of tissue- specific expression pattern analysis of seed storage protein genes using microarray, glutelin and most of prolamin genes were expressed only in seed endosperm, while a few prolamin and the globulin genes are expressed in seed endosperm and germinating seed. As a result of isolating promoter regions of the seed storage protein genes and analyzing their expression pattern in seed, glutelin type C1 promoter showed expression in whole seed, and glutelin type B5 and α-globulin promoter showed strong expression. This paper reviewed on the structure and expression profile of rice seed storage protein genes, and will provide information on the recent research status to the researchers who are studying on the improvement of seed traits and production of substances.
PCR-based allele specific markers for bacterial blight resistance gene in rice.
Yeon-Jae Hur,Jong-Hee Lee,Ji-Ung Jeung,Ji-Yoon Lee,Jun-Hyun Cho,Hyun-Jin Park,You-Chun Song,Myung-Gyu Oh,Un-Sang Yeo,Choon-Woo Lee,Min-Hee Nam 한국육종학회 2012 한국육종학회 심포지엄 Vol.2012 No.07
The use of functional markers, it is expected to make direct identification about genetic diversity at DNA level and overcome the problem of recombination /linkage. These markers can be used to identify interesting alleles in a breeding program and indirectly select for the trait, saving money, time and labor. Bacterial blight of rice caused by Xanthomonas oryzaepv. Oryzae is a destructive disease in rice production worldwide. No bactericide is effective to control the bacterial blight disease yet. Xa3, which is a gene conferring resistance to BB of the rice plant has been previously characterized by map-based cloning. We have cloned and sequenced the Xa3/xa3 gene in Korean cultivar, Hwayoung, Ilmi and Goun with gene specific primers. Our work detected polymorphisms and PCR-based allele specific SNP markers were developed. Susceptible or resistant individuals from an F2 population developed from across between Milyang244 and Ilmi, Korean germplasms and near isogenic lines carrying BB resistance genes were screened with allele specific markers. We found that the genotype completely matched their phenotype to BB using ASP-primers. These markers could be effective to marker-assisted selection for the Xa3 gene in rice breeding programs.
Long Versus Short Drug-Eluting Stent In One Patient With Different Vessel: Which Is Better? (초)
( Min Kyu Kang ),( Ung Kim ),( Jong Seon Park ),( Won Jong Park ),( Young Jo Kim ),( Yoon Kyung Cho ),( Hyuk Joon Yoon ),( Chang Wook Nam ),( Seung Ho Hur ),( Yoon Nyun Kim ),( Kwon Bae Kim ) 대한내과학회 2012 대한내과학회 추계학술대회 Vol.2012 No.1
Atmospheric Ozone Concentrations in the Industrial and Traffic Areas of Pusan City
Yoon,Ung Chan,Yun,Il,Kim,Jack C.,Kim,Jong-myung,Kim,Min-sook 부산대학교 환경문제연구소 1984 環境硏究報 Vol.2 No.-
부산 시청, 연산동, 감전동, 부산진구 및 명륜동 등의 5개지역에서 Ozone분석기를 이용하여 대기 중의 오존 농도를 측정한 수치는 다음과 같다(괄호 안은 최대치). 0.014(0.062), 0.031(0.230), 0.041(0.121), 0.021(0.081) 및 0.023ppm(0.091ppm). 가장 낮은 0.014ppm의 부산 시청 주위 농도는 인접한 바다 바람에 의한 희석 때문이라고 생각되며, 공업지역의 감전동의 0.041ppm은 대기중의 배기가스에 기인된 것이라 사료된다. 5개 지역의 오존 최대치가 미국의 기준치(0.08ppm) 및 일본의 0.06ppm을 초과하는 농도이다. 인간의 보건, 식물 및 유기고분자에 미치는 영향을 평가하였다.