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      • OS Security Enhancement System by Considering Security Level

        Tai-Hoon Kim,Gil-cheol Park,Seok-soo Kim 보안공학연구지원센터 2007 International Journal of Multimedia and Ubiquitous Vol.2 No.3

        Trusted operating systems (OS) provide the basic security mechanisms and services that allow a computer system to protect, distinguish, and separate classified data. Trusted operating systems have been developed since the early 1980s and began to receive National Security Agency (NSA) evaluation in 1984. The researches about trusted OS are proceeding over the world, and new product type using the loadable security kernel module (LSKM) or dynamic link library (DLL) is being developed. Most important concept in this paper is Security Level proposed by Dr. Tai-hoon Kim, because this concept should be considered in every operational environment. This paper assumed security level 1st proposed by Dr. Taihoon Kim, and proposes a special type of product using LSKM and specific conditions for operational environment should be.

      • Definition of Security Practices in STP for SLMM

        Tai-Hoon Kim 보안공학연구지원센터 2008 International Journal of Hybrid Information Techno Vol.1 No.1

        To manage security level of information system (IS), organizations must select security practices (SP) first, and then apply them according to security level. SP can be divided into 2 groups security management part (SMP) and security technology part (STP), and some SPs in SMP were proposed already by Drs. Tai-hoon Kim and Kouichi Sakurai [1]. In this paper, we propose some SPs in STP to construct STP for Security Level Management Model (SLMM).

      • SCOPUSKCI등재

        Molecular Theory of Plastic Deformation (Ⅲ)$^*$

        Kim, Jae-Hyun,Ree, Tai-Kyue,Kim, Chang-Hong Korean Chemical Society 1981 Bulletin of the Korean Chemical Society Vol.2 No.3

        (1) The flow data of f (stress) and ${\dot{s}$ (strain rate) for Fe and Ti alloys were plotted in the form of f vs. -ln ${\dot{s}$ by using the literature values. (2) The plot showed two distinct patterns A and B; Pattern A is a straight line with a negative slope, and Pattern B is a curve of concave upward. (3) According to Kim and Ree's generalized theory of plastic deformation, pattern A & B belong to Case 1 and 2, respectively; in Case 1, only one kind of flow units acts in the deformation, and in Case 2, two kinds flow units act, and stress is expressed by $f={X_1f_1}+{X_2f_2}$where $f_1\;and\;f_2$ are the stresses acting on the flow units of kind 1 and 2, respectively, and $X_1,\;X_2$ are the fractions of the surface area occupied by the two kinds of flow units; $f_j=(1/{\alpha}_j) sinh^{-1}\;{\beta}_j{{\dot{s}}\;(j=1\;or\;2)$, where $1/{\alpha}_j\;and\;{\beta}_j$ are proportional to the shear modulus and relaxation time, respectively. (4) We found that grain-boundary flow units only act in the deformation of Fe and Ti alloys whereas dislocation flow units do not show any appreciable contribution. (5) The deformations of Fe and Ti alloys belong generally to pattern A (Case 1) and B (Case 2), respectively. (6) By applying the equations, f=$(1/{\alpha}_{g1}) sinh^-1({\beta}_{g1}{\dot{s}}$) and $f=(X_{g1}/{\alpha}_{g1})sinh^{-1}({\beta}_{g1}{\dot{s}})+ (X_{g2}/{\alpha}_{g2})\;shih^{-1}({\beta}_{g2}{\dot{s}})$ to the flow data of Fe and Ti alloys, the parametric values of $x_{gj}/{\alpha}_{gj}\;and\;{\beta}_{gs}(j=1\;or\;2)$ were determined, here the subscript g signifies a grain-boundary flow unit. (7) From the values of ($({\beta}_gj)^{-1}$) at different temperatures, the activation enthalpy ${\Delta}H_{gj}^{\neq}$ of deformation due to flow unit gj was determined, ($({\beta}_gj)^{-1}$) being proportional to .$k_{gj}$, the jumping frequency (the rate constant) of flow unit gj. The ${\Delta}H_{gj}\;^{\neq}$ agreed very well with ${\Delta}H_{gj}\;^{\neq}$ (self-diff) of the element j whose diffusion in the sample is a critical step for the deformation as proposed by Kim-Ree's theory (Refer to Tables 3 and 4). (8) The fact, ${\Delta}H_{gj}\;^{\neq}={\Delta}H_{j}\;^{\neq}$ (self-diff), justifies the Kim-Ree theory and their method for determining activation enthalpies for deformation. (9) A linear relation between ${\beta}^{-1}$ and carbon content [C] in hot-rolled steel was observed, i.e., In ${\beta}^{-1}$ = -50.2 [C] - 40.3. This equation explains very well the experimental facts observed with regard to the deformation of hot-rolled steel..

      • POS System Design in Security Level 1st

        Seok-soo Kim,Tai-hoon Kim 보안공학연구지원센터 2007 International Journal of Multimedia and Ubiquitous Vol.2 No.2

        POS system is a supply net administration system for customer management. It becomes an essential element in distribution industry to construct database, and uses XML-Encryption to complement PKI techniques and standards for security. POS system has four advantages. First, it does not have to be certificated and transmit data every time because there is no server. Second, it can integrate database by using XML and improve portability of program itself. Third, transmitted data is safe because of XML-Encryption. Fourth, processing speed will be faster because it gathers data from data transmission. All systems should be designed by considering security level to reduce non-necessary burdens. The concept of security level management was developed by Dr. Tai-hoon Kim a few months ago, and this paper used this idea. In this paper, Security Level 1st environment was considered to design POS systems.

      • 백혈병 세포를 이용한 종양-림프구 혼합면역반응의 임상적 의의

        김희제,조현일,김태규,한훈,김춘추,민우성 대한조혈모세포이식학회 2000 대한조혈모세포이식학회지 Vol.5 No.1

        본 연구는 골수성 백혈병세포와 공여자 유래의 말초 혈액 단핵구를 실험관 내에서 배양하여 백혈병 특이 세포 독성 T 세포를 HLA 일치 형제 공여자로부터 유도하고, 유도된 T 세포의 특성을 규명하여 조혈모세포이식 후의 임상적인 소견과의 연관성을 조사하고자 하였다. 만성기 5례, 가속기 3례, 급성기 2례를 포함하는 10례의 만성 골수성 백혈병 환자들과 1차 완전 관해 상태에 있는 2례의 급성 골수성 백혈병 환자들의 말초혈액에서 수상돌기 세포를 유도하여 항원제시세포로 사용하였다. 백혈병 세포에 대한 세포 독성 T 세포의 효과적인 유도는 급성 골수성 백혈병, 만성 골수성 백혈병의 만성기와 급성기, 가속기의 순서였다. 세포 독성은 세가지 표적 세포인 K562 세포주, 백혈병 세포와 환자의 PHA 자극세포에 대한 세포독성 실험을 통해 세포독성 T 세포에 의한 것인지 또는 자연 살해 세포 (NK 세포)에 의한 것인지 구별할 수 있었다. 세 가지 표적세포에 대한 세포살해는 결과를 종합하여 동종 조혈모 세포이식 후 백혈병의 제발 가능성을 예측할 수 있었다. 즉 세가지 표적세포들 중 한 가지에서라도 양성 반응을 보인 경우 이식편대 백혈병 효과로 인해 백혈병 재발률이 낮았다. 2례의 만성 골수성 백혈병 가속기 환자들에서 유도된 백혈병성 수상돌기 세포들은 세포의 형태학적 소견과 유세포 분석기를 사용한 면역 표현형이 수상돌기 세포와 동일하였으나 이를 이용해 유도한 세포독성 T 세포는 유의한 활성을 나타내지 않았다. 결론적으로 백혈병 세포에 대한 공여자 기원의 항 백혈병 세포독성 T 세포는 Interleukin-2로 자극하여 실험관내 배양이 가능하며, 이를 통해 질환의 특성이나 백혈병 세포의 생물학적 이질성에 따른 세포 살해능의 다양성을 규명할 수 있을 것으로 사료된다. Background:Allogeneic bone marrow transplantation (BMT) is an effective treatment for a large number of patients suffering from malignant hematological disorders. An immune-mediated graft-versus-leukemia (GVL) effect is an important feature of this treatment modality. Although numerous clinical and experimental data have given evidence for both T and NK cells involved in this phenomenon, leukemic relapse and graft-versus-host disease (GVHD) mediated by T cells still remain the major problems of allogeneic BMT. In this study, we tried to define the characteristics of anti-leukemic CTLs and to evaluate the clinical implications of the cellular immunity in leukemic patients. Methods:Leukemic cells were incubated concurrently with peripheral mononuclear cells isolated from HLA-matched sibling donors. Cytotoxic T lymphocytes (CTLs) have been generated from peripheral blood cells of 12 patients with chronic myelogenous leukemia (CML) including 5 in chronic phase (CP), 3 in accelerated phase (AP), 2 in blastic crisis (BC) and 2 patients with acute myelogenous leukemia (AML) in first complete remission. The activity of CTLs and NK cells was measured by 51Cr release assay using autologous leukemic cells, K562 cell line and patient's PHA blasts as target cells. Results:The efficacy of generating CTLs against leukemic target cells were AML, CML-CP and CML-BC, CML-AP in order. Low leukemia relapse events was found to be associated with the strong intensity of cytotoxcity for K562 cell lines, and in addition to this, if we combine the cytotoxicity effects for all thee target cells, the possibility of relapse after allogeneic stem cell transplantation (SCT) was significantly predictable. Any significant association of the cytotoxicity against three target cells with GVHD was not found. Sex-matching or mismatching between donor and recipient did not affected on the NK cell activity. Conclusion:Our results demonstrated that donor-derived antileukemic cytotoxic T-cells against patient's own leukemic cells are producible in vitro and the activity of CTLs and NK cells may be variable according to disease-specificity or to biological heterogeneity of leukemia. If the specific, stable and reproducible anti-leukemic CTLs could be generated in vitro, these CTL lines could be used for the treatment of relapsed or predictable relapse high-risk leukemia after allogeneic BMT and for post-mini-transplantation immunotherapy in the near future.

      • SCIESCOPUSKCI등재
      • 흉통의 양상에 따라 분류한 불안정형 협심증 환자의 임상적 소견의 비교

        김명수,김성구,정호석,온영근,신원용,김철현,최태명,현민수,권영주 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

        Background and aims : The clinical syndrome unstable angina pectoris that encompasses a variety of symptoms and clincal presentations of transient episode of myocardial ischemia, was devided to several subgroups. Also, it has variable pathophysiologic factors to cause myocardial ischemia. According to clincal presentation, coronary angiographic finding and prognostic factor, the result of unstable angina pectoris is variable. In fact, there were a few data reported on the prognosis of wide spectrum of patients with unstable angina. However, the precise risk of subgroups according to classitication has not been established because it was difficult to compare between studies. We classified unstable angina pectoris by clinical nature of chest pain, and performed to establish and compare the clinical presentations, coronary angiographic findings, treatement and prognosis of patients with unstable angina within subgroups of classification. Methods : Retrospenctive data for 164 unstable angina pectoris patients admitted to the Internal Cardiology Division of Soon Chun Hyang University Hospital from May 1996 to July 1999 was analyzed. The patients were classified into one of the following categories: Class I, new onset of severe angina; Class II, acceleration of previous chronic stable angina; Class III, angina at rest. Clinical presentations, echocardiographic findings, coronary angiographic findings, treatment and prognosis were compared. Results : From the total 164 patients, the subjects of classes were as follows : Class I, 46 cases (28.1%); Class II, 74 cases (45.1%); Class III, 44 cases (26.8%). In view of age distribution, the 7th decade had the highest incidence, and then, 6th, 8th decades were followed. There was no baseline differences among the 3 classes with respect to gender, number of risk factors. Significantly, class II showed more severe findings in abnormal Q wave 15 cases (20.8%), total occclusive lesion 10 cases (20.8%) and three vessel coronary disease 11 cases (22.9%) than other classes. The change of ST segment was significantly apparent (p<0.02) among class I 28 cases (60.8%), class III 26 cases (59.0%), comparing with class II 30 cases (40.5%). Class III had the higher incidence of one vessel coronary artery disease than class I and III. The heparin treatment was performed in 99 cases (60.1%). The incidence of nonfatal myocardial infarction was much more in class I and III, each 4 cases (8.7%, 9.8%) than in class II 1 cases (1.4%). In-Hospital death was occurred in class I and II, each 1 case. Conclusion : The patients with the acclerated angina from chronic stable angina had more severe coronary artery disease than other classes, but they had better in-hospital prognosis.

      • SCIESCOPUSKCI등재
      • 근대문학작품의 도시풍경구도에 나타난 시·공간의 체험적 인식에 관한 연구 : 소설 "소설가 구보씨의 일일"을 중심으로 Focused on the novel entitled "a novelist Gubo's day"

        김기범,김태영 淸州大學校 都市·地域開發硏究所 2000 都市·地域開發硏究 Vol.8 No.2

        The purpose of this study aims to understanding a common mental image between architecture and literature work in the modem ages, and especially the experiential recognition of time·space described on townscape. Following the result, Kyong-song have been represented to compound emotion with modem architecture established in 1930s of Modem Ages. First of all, the experiential recognition have been connected to the conflict structure between past and present townscape in the novel entitled "a novelist Gubo's day" by Park Tai-Won. And so on, such townscape consciousness was one of the immediate causes of the reminiscence.

      • 약물전달체를 위한 폴리에틸렌글리콜과 폴리카프로락톤을 이용한 나노입자

        김태형,채수영,최창용,김동곤,김명열,나재운 한국공업화학회 2004 응용화학 Vol.8 No.2

        The self-aggregation behavior and microscopic characteristics of the PEG-b-PCL copolymer self-aggregates, prepared by solvent evaporation method, were investigated by `H NMR, dynamic light scattering (DLS), and fluorescence spectroscopy. The PEG-PCL block copolymer formed nano-sized self-aggregates in an aqueous environment by intraand/or intermolecular association between hydrophobic PCL chains. Then, drug loading and its release behavior of clonazepam loaded PEG-b-PCL nanoparticles were investigated. The result revealed that hydrophobic-hydrophilic balances played a crucial role for drug loading and its release behaviors.

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