세계 주요 컨테이너선사의 물류서비스 추진 사례 및 전략에 관한 연구

류동근,엄윤대,조삼현 한국해양대학교 국제해양연구소 2001 韓國海洋大學校 人文社會科學論叢 Vol.13 No.1

Abstract The container shipping industry has faced new business environment over the last decades. With the globalization of business, the diversification of shippers' demand, and the introduction of e-business container shipping operators have to diversify their business and provide value added logistics services in order to gain a competitive advantage in the changing business environment. In particular, major container shipping companies provide not only maritime transport services but also logistics services to offer their customers a high level of integrated transport services. Thus, this paper aims to examine logistics services and a business strategy of major container shipping companies through a case study. It was found in this research that major container shipping companies utilize a different logistics service strategy. In order to strengthen their logistics business they established international logistics networks by operating exclusive container terminals and logistics centers in major regions worldwide. Also, they involve in IT business and provide on-line services to offer a high level of logistics services to their customers. Additionally they provide value added logistics services such as warehousing, customs clearance, packing, processing, documentation, inventory control, and freight forwarding by acquiring 3PL companies or in co-operation with them.

Metarizium anisopliae (Metschn.) Sorok이 생산하는 Lactobacillus plantarum 용균효소의 분리, 정제 및 특성

류기철,함병권,백운하,유주현,배동훈 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.6

김치저장성을 향상시키기 위하여, Lactobacillus plantarum 용균효소 생산균주를 토양으로부터 분리한 후 그 효소를 정제하고 특성을 살펴보았다. 본 균주의 배양학적 및 형태학적 특성 등을 검토한 결과 Metarrisium anisopliae (Metschn). Sorok으로 동정되었으며, 본 효소는 affinity adsorption, CM-Sephadex C-50 column chromatography를 통하여 40%의 수율과 75배 정제도로 정제되었다. 효소활성의 최적 pH와 온도는 각각 4.0, 40℃였으며, pH 3.0~9.0, 60℃까지 효소의 안정성이 유지되었다. SDS-PAGE 및 gel filtration으로부터 본 효소의 분자량은 40,000 daltons인 monomeric protein임을 확인하였다. 본 효소는 Lactobacillus plantarum 세포벽 peptidoglycan의 peptide linkage를 절단 하는 endopeptidase였으며, 용균 spectrum으로부터 김치발효시 유용균인 Leuconostoc mesenteroides에 대해서는 활성을 거의 나타내지 않음을 확인할 수 있었다. 본 효소의 활성은 Ag^+, N-bromosuccinimide (NBS)에 의해서 완전히 저해되었으며, NBS에 의해서 활성이 저해된다는 사실로부터 본 효소는 활성에 tryptophan residue가 관여하는 것으로 확인되었다. 본 효소는 산성 아미노산의 함량이 염기성 아미노산의 함량에 비하여 높았으며, alanine, glycine, proline, tyrosine의 함량 또한 매우 높았다. To improve the preservation of Kimchi, we isolated Lactobacillus plantarum lytic enzyme-producing strain from soil, and the enzyme was purified and characterized. From the observation of cultural and morphological characteristics, the isolated strain was identified as Metarrisium anisopliae (Metschn). Sorok. The enzyme was purified to 75-folds with 40% yields through affinity adsorption and CM-Sephadex C-50 column chromatography. The optimum pH and temperature for lytic activity are 4.0 and 40℃, respectively, and the enzyme acitivity is stable between pH 3.0 and 9.0 and up to 50℃. The enzyme is a monomeric protein with molecular weight of 40,000 daltons by SDS-FAGE and gel filtration. The enzyme is endopeptidase which breaks the peptide linkage of Lactobacillus plantarum peptidoglycan. The lytic action spectra confirmed that Leuconostoc mesenteroides, a useful strain for the fermentation of Kimchi, is not lysed by the enzyme. The enzyme activity is inhibited by N-bromosuccinimide (NBS), which probably indicates the involvement of tryptophan residue in active site of the enzyme, and also inhibited by Ag^+. The amino acid composition analysis showed that the enzyme contains more acidic amino acids than basic ones, and composition of alanine, glycine, proline and tyrosines was very high.

다양한 잡초로부터 생리활성물질의 탐색

김창진,강병화,유인자,박동진,이현선,김영호,유익동 충남대학교 약학대학 의약품개발연구소 1996 藥學論文集 Vol.12 No.-

다양한 잡초로부터 유용 생리활성물질을 탐색하고자 46종 잡초의 methanol 추출액을 대상으로 50~100 ㎍/㎖ 농도로 실험한 결과, 항균 활성에 있어서는 파리풀, 까실쑥부쟁이, 중머리대가리, 큰엉겅퀴, 부처꽃 등이 antobleb 활성에 있어서는 낙지다리, 밭뚝외풀, 까실쑥부쟁이, 술패랭이꽃 등이 항암활성에 있어서는 파리풀, 골풀, 밭뚝외풀, 까실쑥부쟁이, 술패랭이꽃, 겨우살이 등이 항산화활성에 있어서는 골풀, 물레나물, 청비녀골풀, 금불초, 방울고랭이, 좀고추나물 등이 비교적 강한 활성을 나타내었다. (1996년 4월 12일 접수, 1996년 8월 8일 수리) To search for bioactive compounds from plant resources, 80% methanol extracts of 46 species of weeds were screened for their activities of antimicrobial, antioxidative, antiblebing, antitumor and herbicidal. Among extracts tested, some showed activities at the concentration of 50 to 100 ㎍/㎖. Phryma leptostachya var. asiatica, Aster ageratoides, Centipeda minima, Cirsium pendulum. Lythrum anceps showed antibacterial activity. Penthorum chinense, Lindernia procumbens, Aster ageratoides, Dianthus superbus var. longicalycinus showed antiblebing activity. Phyma leptostachya var. asiatica, Juncus effusus var. decipiens, Lindernia procumbens, Aster ageratoides, Dianthus superbus var. longicalycinus, Viscum album var. coloratum showed antitumor activity. Juncus effusus var. decipiens, Hypericum ascyron, Juncus papillosus, Inula britannicar var. chinensis, Scirpus wichurae, Hypericum laxum showed antioxidant activity.

Comparative Port Performance Analysis of Italian Ports

Enrico D’agostini,Dong-Keun Ryoo,So-Hyun Jo 한국항해항만학회 2015 한국항해항만학회지 Vol.39 No.5

Recently, the fierce competitions in the shipping industry and the global economic downturn have heavily influenced ports’ operational strategies. In order for port authorities to remain competitive at an international level and to provide more accurate information to develop National policies, ports are required to analyse and improve operations’ efficiency. In this paper, the efficiency of 19 Italian ports in 2013, handling different types of cargoes, is assessed through the application of Data Envelopment Analysis (DEA), with constant return to scale (CRS) and variable return to scale (VRS). The purpose of this study is to analyze the efficiency of Italian ports and evaluate whether differences in size and specialization of each port (or cargo handled) are directly correlated with ports' efficiency.

The Economic Impact of Maritime Piracy in the Gulf of Aden: challenges and implications

Enrico D’agostini,Dong-Keun Ryoo,So-Hyun Jo 한국항해항만학회 2015 한국항해항만학회지 Vol.39 No.5

The purpose of this paper is to analyze maritime piracy and its economic implications with particular attention to attacks registered in the Gulf of Aden, The paper also aims to investigate how the International community, along with Sovereign States, should allocate resources in order to make the seas a safer place and describe how closely inter-related maritime piracy, preventive and punitive measures put in place by Governments are. Elements of economics and ergonomics are taken into account in order to properly investigate the major legal issues relating to maritime security. The paper proposes a cost-benefit analysis in order to investigate in theory what is the rationale behind engaging in criminal behavior and recommend some solutions to the issue to be undertaken by the International community. It is concluded that in order to cost effectively fight piracy, a mix of more coordinated National and International laws, standardized and increased punishment levels among jurisdictions and extended patrol controls are needed.

2013년도 시판된 Dexibuprofen과 Ibuprofen의 광학 순도 측정

류상현,이상헌,서해찬,송정석,류동현,유정재,김현영,이재환,류재정,Ryoo, Sang Hyun,Lee, Sang Heon,Seo, Hae Chan,Song, Jung Suk,Ryoo, Dong Hyun,Yu, Jeong Jae,Kim, Hyun Young,Lee, Jae Hwan,Ryoo, Jae Jeong 대한화학회 2014 대한화학회지 Vol.58 No.3

2013년 국내에서 시판된 7개의 이부프로펜과 11개의 덱시부프로펜의 광학순도를 키랄 HPLC로 조사하였다. Chiralcel OD-H 칼럼과 LUX-Cellulose-1 칼럼을 키랄 정지상으로 사용하였고, hexane:isopropanol:acetic acid가 100:1:0.1로 혼합된 용액을 전개용매로 사용하여 흐름속도 1.0 mL/min에서 분석하였다. 각 시료를 최소 3회 이상 분석하여 얻은 평균값을 각각 계산하여 데이터로 이용하였고, 이들의 상대표준편차 평균값도 0.19%로 아주 작게 나타나 실험의 정밀도가 높음을 확인하였다. 실험에 사용된 11개 덱시부프로펜의 광학순도 평균값은 처음 판매가 허가된 2004년의 평균값인 99.2%에 비해 낮아졌지만 2010년의 평균값인 95.6% 보다는 높은 97.5%를 보였다. 그리고 실험에 이용된 모든 이부프로펜 두 거울상 이성질체의 조성비는 2010년 조사값(44:56)과는 달리 거의 50:50으로 얻어졌다. The optical purity of 11 commercial dexibuprofens and 7 ibuprofens sold in Korea in 2013 were examined by chiral HPLC. The Chiralcel OD-H column and LUX-Cellulose-1 column were used as chiral stationary phases and the mixed eluent of hexane:isopropanol:acetic acid as 100:1:0.1 was used as a mobile phase with a flow rate of 1.0 mL/min. Each data was obtained from an average value of at least three different experiments for each sample and the average value of relative standard deviation of them appeared very small, 0.19%. Average optical purity value (97.5%) of eleven commercial dexibuprofens used in this study were smaller than those of 9 years ago (99.2%), but larger than four years ago (95.6%). Enantiomeric ratios of (R)- and (S)-isomers of seven ibuprofen samples used in this experiment were achieved at about 50:50 which was different with the result (44:56) from four years ago.

2013년 시판된 나프록센의 광학순도 측정

서해찬,송정석,류상현,이상헌,류동현,유정재,류재정,Seo, Hae Chan,Song, Jung Suk,Ryoo, Sang Hyun,Lee, Sang Heon,Ryoo, Dong Hyun,Yu, Jeong Jae,Ryoo, Jae Jeong 대한화학회 2014 대한화학회지 Vol.58 No.2

시판되는 (S)-naproxen을 강염기 조건에서 라세미화하였다. 라세미화된 naproxen 시료를 분석하여 (R)- 및 (S)-naproxen의 피이크 위치를 확인한 후, 2013년 국내에서 시판된 19개 naproxen의 광학순도를 키랄 HPLC로 조사하였다. Chiralcel OD-H 칼럼과 ChiralHyun-LE(S)-1 칼럼 및 LUX-Cellulose-1 칼럼을 키랄 정지상으로 사용하였고, hexane:isopropanol:acetic acid가 100:1:0.1로 혼합된 용액을 전개용매로 사용하여 흐름속도 1.0 mL/min에서 분석하였다. 각 시료를 최소 3회 이상 분석하여 얻은 평균값을 각각 계산하여 데이터로 이용하였고, 이들의 상대표준편차도 계산하여 그 값이 아주 작게 나타난 것을 확인하였다. 세 종류의 다른 칼럼에서 각각 측정한 광학순도 값이 서로 아주 유사한 값을 보여주었으며, 측정된 naproxen의 광학순도는 이들의 광학순도 데이터가 처음 보고된 2010년 시료의 광학순도 평균값인 98.17%에 비해 높은 99.32%를 보였다. Commercial (S)-naproxen was racemized under strong basic condition. After checking the peak position of (R)- and (S)-naproxen by analysis the recemized naproxen, optical purity of 19 commercialized naproxens sold in 2013 in Korea were examined by chiral HPLC. The Chiralcel OD-H column, ChiralHyun-LE(S)-1 column and LUX-Cellulose-1 column were used as chiral stationary phases and the mixed eluent of hexane:isopropanol:acetic acid as 100:1:0.1 was used as a mobile phase with a flow rate of 1.0 mL/min. Each data was obtained from an average value of at least three different experiments for each sample and the relative standard deviation of them appeared very small. The average optical purity values obtained from three different chiral columns were very similar and the total average optical purity value (99.32%) of nineteen commercialized naproxens used in this study were larger than those of three years ago (98.17%).

소아의 유행성 출혈열 1예 보고 : 급성 신부전증이 동반된 예 A case with acute renal insufficiency

유경현,민경옥,이동근,유병훈 중앙대부설한국의과학연구소 1985 한국의과학 Vol.17 No.1

A Case of Pneumonia Caused by Ewingella americana in a Patient with Chronic Renal Failure

Ryoo Nam Hee,Jeon Dong Seok,Kim Jae Ryong,Kim Hyun Chul,Ha Jung Sook 대한의학회 2005 Journal of Korean medical science Vol.20 No.1

A Systematic Approach to Effectively Treat Chronic Wounds Caused by Self-Harm: Two Case Reports

Hyun Jung Ryoo,Kim Dong Yeon 대한창상학회 2022 Journal of Wound Management and Research Vol.18 No.3

Non-suicidal self-injury (NSSI) refers to the intentional act of causing physical injury without a clear suicidal intent. Patients in a dissociative state attempt to fulfill an underlying psychological need by inflicting cutaneous wounds on themselves. The mechanisms of NSSI can vary from mild to severe depending on the degree of soft tissue destruction. Self-destructive behavior triggered by psychosis, a different classification of self-injury, may have a variety of drivers, such as hallucination and delusion. Repetitive self-harm often results in chronic wounds and associated infections. As a conventional approach is inadequate for managing self-harm wounds, treating patients who self-injure presents many challenges for physicians. In the presence of hard-to-treat primary disorders, a systematic approach with custom procedures that may deviate from traditional wound management principles should be carried out within an interdisciplinary framework that considers the psychiatric condition. The authors provide several recommendations for appropriate management of chronic wounds caused by self-mutilation. Here, we report the cases of a 47-year-old female patient who presented with NSSI and a 67-year-old male patient with self-injurious behavior of psychosis, respectively.