E. coli에 의한 1세 미만 요로 감염의 치료에 방광요관역류가 미치는 영향

김형대,이상윤,이균우,정현기 고신대학교의과대학 2006 고신대학교 의과대학 학술지 Vol.21 No.2

Background : Vesicoureteral reflux(VUR) is the major cause of urinary tract infection(UTI) in children. The study was done to confirm the influence of vesicoureteral reflux on treatment of urinary tract infection. Methods : One hundred seventy one patients below 1 year old diagnosed with UTI by Escherichia. coli (E. coli) in the Department of Pediatrics, Dae-Dong Hospital from January, 2001 to December, 2005 were retrospectively enrolled to analyze relevant information obtained from medical record, including hematologic and urine analysis, renal ultrasonography, 99mTc-DMSA renal scan, antimicrobial susceptibilities and response of treatment, comparing two group of absence and presence of VUR. Results: Leukocytosis and decreased Hemoglobin level was predominent and the rate of bacteriuria and nitrite positivity were 84.1% and 40.4% respectively. Renal ultrasonography didn't contribute to the prognostication of VUR. Presentation of photopenic area in 99mTc-DMSA renal scan was related to VUR and the severity of VUR was significantly correlated with renal scar formation(P<0.05). Average count of administrated intravenous cefotaxime for treatment of UTI was 2.4 times until afebril state, 9.6 times until loss of pyuria and 2.2 times until no growth of Escherichia. coli in urine. Conclusion : There was no differentiations in WBC count, Hb level, urine analysis and response of treatment estimated by count of administrated intravenous cefotaxime until afebrile state, loss of pyuria and no growth of E. coli in urine between the group of absence and presence of VUR.

산업용 이차전지의 열화진단에 관한 연구

장대경,황호석,박민기 서울産業大學校 2005 논문집 Vol.54 No.3

This paper proposes a new degradation diagnosis method of secondary battery in order to improve a battery economy. In the proposed method, a bad cell is detected by the measurement of DC internal resistance and the battery capacity is estimated by the electric discharge test in a short period of time, which can be used to determine the time to replace the battery. Through the computer simulation and actual experimentation, the proposed method's validity is confirmed by comparing and analyzing the performance. As a result, we show that it is possible to estimate the accurate capacity of secondary battery in a short space of time.

재원기간중 사망한 급성 심근경색증 환자의 임상적 특징

현대우,김기식,신이철,박소영,배장호,한창엽,김윤년,김권배 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.9

水平曲線 H形보의 Warping의 影響에 關한 硏究

김기대 대구대학교 산업기술연구소 1986 産業技術硏究 Vol.5 No.-

The virtual work method for the analysis of horizontally curved girders is adopted in the present research. The girders were used continuous spans having constant circular-are curvature in a span, H-shaped constant cross sections, constant moments of inertia, and concentrated loadings. The virtual work method was in which the effect of warping restraint is not considered. Numerical examples were compared with the values of the differential equation method. It is found that shear force and bending moment were slightly effected, but deflections were more greatly.

在學生 實態調査

安秉基,申大鉉 충남대학교 학생생활연구소 1972 學生生活硏究 Vol.1 No.-

모자형 단면부재의 평균 압괴하중

安大植,柳澤仁,韓秉基 弘益大學校 科學技術硏究所 1993 科學技術硏究論文集 Vol.3 No.-

In this study, the mean crushing load of thin-walled closed hat and tube type medel subjected to axial compression is investigated. The energy method for calculating the mean crushing load was based on the Wierzbicki theory for tube section and the Ohkubo theory for single hatted section. And the experiments was performed for comparing with the theoretical results. Among the most important observations and conclusions one may list the following: 1) In the analysis of corner, it is more reasonable to consider the stretching energy by circumferential stretching effect. 2) The difference of energy equations between the tube and the single hatted type model have something to do with the presence of bending energy for flange zone, that is, the equation of the single hatted type model is equal to the equation that added the bending energy in flange zone to the tube type model. 3) In the case of double hatted section member, the stretching energy of corner met with flange as well as the bending energy of flange must be added. Also crash modes of double hatted section member was more complicated and one need more investigation about these.

齒科用 Ag-Pd-Cu 3元合金 및 Au添加合金의 時效硬化特性

이기대,곽동주 대구보건대학 1999 대구보건대학 論文集 Vol.19 No.-

The Ag-Pd-Cu alloys containing a small amount of Au is commonly used for dental purposes, because this alloy is cheaper than Au-base alloys for clinical use. However, the most important characteristic of this alloy is age-hardenability, which is not exhibited by other Ag-base dental alloys. The specimens used were Ag-Pd-Cu ternary alloys and Au addition alloy. These alloys were melted and casted by induction electric furnace and centrifugal casting machine in Ar atmosphere. These specimens were solution treated for 2hr at 800% and were then quenched into iced water, and aged at 350~550℃. Age-hardening characteristics of the small Au-containing Ag-Pd-Cu dental alloys were investigated by means of metallurgical microstructures, X-ray diffraction and electron microscope observations, energy dispersed spectra and electron probe microanalysis. Principal results are as follows : The case of hardening in stage Ⅰ was due to the formation of the L1o type face-centered tetragonal PdCu-ordered phase in the grain interior and hardening in stage I was affected by the Cu concentration. In stage Ⅱ, decomposition of the αsolid solution to a PdCu ordered phase(L1o type) and an Ag-rich α₂ phase occurred and a discontinuous precipitation occurred at the grain boundary. From the electron microscope study, it was concluded that the cause of age-hardening in this alloy is the precipitation of the PdCu ordered phase, which has AuCu Ⅰ type face-centered tetragonal structure. Precipitation procedure was α→α+α₂+PdCu→α₁+α₂+PdCu at Pd/Cu =1. Ag-Pd-Cu alloy is more effective dental alloy as ageing treatment and is suitable to isothermal ageing at 450℃.

양자교환 방식에 의한 방향성 결합기의 제작 및 특성연구

소대화,채기병,강기성,윤형도 明知大學校 産業技術硏究所 1992 産業技術硏究所論文集 Vol.11 No.-

In this study, a directional coupler which is fabricated on X-cut LiNbO₃ substrate by using proton exchange method is described. It is found that the directional coupler waveguide varied widely with controlling diffusion process. On the other hand, the on-off state of modulator is performed by annealing process and self-aligned electrodes are used in fabricating the direction coupler. As a results, the direction coupler has good characteristics : the measured on-off switching voltage of about 2.7-3V.

間接螢光抗體法 및 免疫黃金標識法을 이용한 肝吸蟲組織內 抗原性部位에 관한 硏究

成大林,金洙鎭,嚴基善,林漢鍾 고려대학교 의과대학 1988 고려대 의대 잡지 Vol.25 No.3

Indirect fluorescent antibody test and immunogold labeling method were accomplished to observe the antigenic localization in the tissues of adult Clonorchis sinesis. Immunoglobulins (IgG) for the reaction were obtained from white rats and rabbits, at eight weeks after experimental infection with 50 and 500 metacercariae of C. sinensis, respectively. Frozen sectioned adult worm antigen (8μm) and FITC-conjugated goat anti-rat, rabbit IgG were used for indirect fluorescent antibody test. On the other hand, sectioned tissue antigen embedded in Lowcryl HM 20 medium and secondary antibody protein A gold complex (particle size:12 nm) were used for immunogold labeling method. In the results, fluorescence or gold particle were not observed on the tissue antigens of the worm when reacted with the noninfected control IgG. However, with the infected animal groups IgG, fluorescence or gold particles were observed on the interstitial matrix (body fluid) between the various organs, such as the tegumental cells, parenchyma, testes, receptaculum seminis. And the cecal epithelium including cecal contents and epithelium of excretory bladder also showed strong reaction. Therefore, antigenic materials which stimulate the IgG antibodies against the host were thought to be fluid substances and digestive enzymes or excretory materials which make up the interstitial matrix in the tissues of the worm.

Hg^2+에 의한 토마토 뿌리조직 마이크로솜 H^+-ATPase의 가역적 저해

신대섭,조광현,김영기 충북대학교 첨단원예기술개발연구센터 1999 연구보고서 Vol.4 No.-

토마토 뿌리조직의 마이크로솜 ATPase 활성에 대한 중금속의 효과를 조사하기 위하여 뿌리조직으로부터 마이크로솜을 분리하였고, enzyme-coupled assay를 이용하여 마이크로솜 이온펌프(ATPase)의 활성을 측정하였다. 여러 가지 중금속 이온들 중 Hg2+은 마이크로솜 ATPase 활성을 농도 의존적으로 저해하였으며, Gd3+ 과 Fe3+, La3+, Zn2+ 그리고 Pb2+ 등은 마이크로솜 ATPase의 활성을 현저히 저해하면서 동시에 assay에 사용된 효소를 저해하였다. 그러나, CS+과 BA2+은 마이크로솜 ATPase 활성에 영향을 미치지 않았다. Hg2+은 원형질막과 액포막에 위치하는 H+-ATPase들의 활성을 10 μM 이상의 농도에서 급격히 저해하였고, 1 mM 이상의 농도에서 완전히 저해하였으며, 두 효소들에 대한 활성저해의 Ki 값은 각각 80 , μM, 58 μM로 나타났다. Hg2+에 의해 저해된 ATPase의 활성은 DTT의 농도를 증가시킴에 따라 회복되어, HG2+에 의한 ATPase 활성저해는 가역적임을 확인하였다. 이러한 결과들은 Hg2+이 원형질막과 액포막에 위치한 H+-ATPase들을 비선택적이고 가역적으로 저해함을 보여준다. In order to characterize the effects of heavy metal ions on the microsomal ATPase activities, microsomes were prepared from the roots of tomato plant and the activity of microsomal ATPase was measured by an enzyme-coupled assay. Hg2+ inhibited the activity of microsomal ATPase in a dose-dependent manner, while Gd3+, Fe3+, La3+, Zn2+, and Pb2+ inhibited not only the ATPase activity but also the activities of enzymes used in the assay. However, Cs+ and Ba2+ showed no significant effect. Hg2+ inhibited the activities of both plasma membrane and vacuolar membrane H+-ATPases. In the dose-response to Hg2+, the activities of both microsomal H+-ATPases were severely inhibited at the concentration of Hg2+ above 10μM and were completely inhibited at 1 mM Hg2+. Apparent Ki values of Hg2+ on the inhibitions of plasma membrane and vacuolar membrane H+-ATPases were 80 μM and 58 μM, respectively. The Hg2+-induced inhibitions were reversible since the addition of dithiothreitol completely reversed the inhibitory effects of Hg2+.These results suggest that the inhibitory effects of Hg2+ on both plasma membrane and vacuolar membrane H+-ATPases are nonselective and reversible.