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이창엽,조평곤,김지닐,최소영,김창균,최종학,김정민,김유현 高麗大學校 倂設 保健大學 保健科學硏究所 2002 保健科學論集 Vol.28 No.2
To find elements which enable improving Quality of image of chest radiography, we attempted to make comparison between chest radiography used currently with that of the past, and following conclusion was reached: 1) It could be confirmed that a dependance on chest radiography was declining, because proportion of chest radiography against overall radiography decreased. 2) There was a change of kVp to a high voltage in a chest radiography, and use of high kVp became a generalization 3) Exposure time was reduced and exposure dose was curtailed accordingly. 4) Apparatus was mainly comprised of 3-phase rectifier circuit and inverter type. 5) It could be confirmed that frequency of applying additional filters for high kVp radiography was insufficient. 6) There was almost no difference in the condition of exposure between hospitals using film/screen and hospitals using CR. But when CR is used for radiography, it was increase in exposure dose due to increase in tube current and it will be necessary to have continuous study on exposure dose by an increase use of CR in the future.
만성 요통환자의 복부 심부근과 표재근을 중심으로 한 운동 효과 비교
김진산,이창현,조미주,임연욱,정취산,김선엽 대한정형도수치료학회 2005 대한정형도수물리치료학회지 Vol.11 No.1
Objectives: To compare the efficacy of two types specific exercise intervention (deep and superficial abdominal muscle exercises) in the treatment of patients with chronic low back pain (CLBP). Design: A randomized, comparative, repeated-measures. Subjects: Twenty-four patients with CLBP (at least for 3 months), mean age±SD=51.58±16.21 (yrs). Methods: Twenty-four patients with this condition were assigned randomly to two treatment groups. Both first and second group underwent 3 weeks specific exercise treatment program. The first group specific trained for the deep abdominal muscles. The second group specific trained for the superficial abdominal muscles. Results: After intervention, the first group showed a statistically significant reduction in pain intensity and functional disability levels (p<.05). The second group showed no significant change in these parameters after intervention (p>.05). Conclusions: According to results, a "deep abdominal muscle exercises" treatment approach appears more effective than a "superficial abdominal muscle exercises" treatment in patients with CLBP.
의도적인 견갑골 외전이 Sit-and-Reach Test에 미치는 영향
김선엽,지창연,김광수 대한정형물리치료학회 2000 대한정형도수물리치료학회지 Vol.6 No.1
Purpose : This study was done to examine the actual effect of the scapular position in these flexibility tests. The purpose of this study was to examine the differences between the measurement of SRT(Sit-and-Reach Test) without intentional abduction of the scapular (pre-test) and with intentional abduction of the scapular (post-test). The hypothesis is: 1. There is no differences in the SRT result of the pre-test and the post-test. 2. There is no differences in the HJA(Hip Joint Angle) result of the pre-test and the post-test. 3. There is no differences in the Spine Motion Test(SMT) result of the pre-test and the post-test. Method : The total 60 people (30 men, 30 women) were participated in this study. In the pre-test, the subjects were asked to sit on the examination table and try the SRT motion: and then the HJA, SRT and the SMT numerical values were taken. In the post-test, the subjects were instructed to intentionally bring the scapula outward from the midline: and the HJA, SRT and the SMT numerical values were taken. Result : In the pre-test, the SRT result averaged 34.17cm, and in the post-test, the SRT result averaged 36.68cm. The difference was about 2.81cm which showed a significant mean statistically (p<0.01). The measurement increased by 8.22%. The HJA was 85.9˚ in pre-test, and it was 85.5˚ in post-test, giving the 0.4˚ differences. Therefore, it didn't have a statistical mean (p>0.05). The SMT value was 69.28cm in the post-test, about 0.28cm decreased. Therefore, it didn't have a statistical mean(p>0.05). SRT values and HJA values were correlated (p<0.01). SMT values and SRT values (p<0.01), and SMT values and HJA values (p>0.05) were each in counter correlation. Conclusion : The result of the SRT without intentional scapular abduction (34.17cm) and with intentional scapular abduction (36.68cm) showed a significant increase about 8.22% (p<0.01). In SRT, the effect of the intentional scapular abduction on SMT showed no significant means, the pre-test value being 69.59cm and the post-test value being 69.28cm (p>0.05).
박두용,김형아,김창엽,백남원,조정진,김양호,이광묵 가톨릭대학 산업의학 쎈타 산업의학연구소 1989 韓國의 産業醫學 Vol.28 No.4
Trichloroethylene(TCE) is a widely used organic solvent, especially in degreasing process of metal manufacturing, however few data concerning its exposure and poisoning were obt-ainable. This survey was performed for more information of TCE exposure in this country. Urine sanmples were collected from 144 TCE handling workers and 46 non-TCE-exposed workers. TCE concentrations of four workshops in working environment were analyzed. The results were as follows; 1. TCE exposed workers were 48 male and 96 female employees. Average total duration of employment of these workers was 39.0 months, average duration of works per day was 10.7 hours, and average duation of TCE handling was 469.7 minutes. 2. The average concentration of urine total trichloro-compounds was 156.32㎎/ g crea-tinine, and that of trichloroacetic acid was 69.2㎎/g creatinine. Of those workers, 78 workers had the concentrations of urine trichloroacetic acid over 75㎎/g, which is the biological exposure index (BEI) of urine trichloroaxetic acid in Korea. Duration of work per day and duration of TCE- related work were significantly longer in the group of workers whose urine trichloroacetic acid concentration was over the criteria level of BEI. 3. TCE concentrations of three workshops were over the level of ACGIH TLV(threshold limit value), 50ppm in TWA (time -weighted average). In remaining one workshop, duration of TCE related works was only one hour per day. There was statistically significant correl-ation between the concentration of TCE in working environment and the proportion of workers in a workshop whose urinary trichloroacetic acid concentration was over the criteria level of BEI. 4. Responses to self-administered questionnaire were not meaningful for differentiation of psychoneurologica symptoms due to chronic TCE exposure from othres.
이홍림,신승엽,김창은 연세대학교 산업기술연구소 1987 논문집 Vol.19 No.2
Mullite fine powder was prepared from alkoxides and its powder characterization was examined. The average particle size of mullite powder which was prepared at 1300℃, for 3 h was 0.1-0.2㎛ and the surface area was 11.2㎡/g by BET measurement.
Kim, Jihye,Chang, Dong-Yeop,Lee, Hyun Woong,Lee, Hoyoung,Kim, Jong Hoon,Sung, Pil Soo,Kim, Kyung Hwan,Hong, Seon-Hui,Kang, Wonseok,Lee, Jino,Shin, So Youn,Yu, Hee Tae,You, Sooseong,Choi, Yoon Seok,Oh, Elsevier 2018 Immunity Vol.48 No.1
<P><B>Summary</B></P> <P>Acute hepatitis A (AHA) involves severe CD8<SUP>+</SUP> T cell-mediated liver injury. Here we showed during AHA, CD8<SUP>+</SUP> T cells specific to unrelated viruses became activated. Hepatitis A virus (HAV)-infected cells produced IL-15 that induced T cell receptor (TCR)-independent activation of memory CD8<SUP>+</SUP> T cells. TCR-independent activation of non-HAV-specific CD8<SUP>+</SUP> T cells were detected in patients, as indicated by NKG2D upregulation, a marker of TCR-independent T cell activation by IL-15. CD8<SUP>+</SUP> T cells derived from AHA patients exerted innate-like cytotoxicity triggered by activating receptors NKG2D and NKp30 without TCR engagement. We demonstrated that the severity of liver injury in AHA patients correlated with the activation of HAV-unrelated virus-specific CD8<SUP>+</SUP> T cells and the innate-like cytolytic activity of CD8<SUP>+</SUP> T cells, but not the activation of HAV-specific T cells. Thus, host injury in AHA is associated with innate-like cytotoxicity of bystander-activated CD8<SUP>+</SUP> T cells, a result with implications for acute viral diseases.</P> <P><B>Highlights</B></P> <P> <UL> <LI> During acute hepatitis A (AHA), non-HAV-specific memory CD8<SUP>+</SUP> T cells are activated </LI> <LI> Non-HAV-specific CD8<SUP>+</SUP> T cells are activated by IL-15 produced by HAV-infected cells </LI> <LI> CD8<SUP>+</SUP> T cells of AHA patients exert TCR-independent, innate-like cytotoxicity </LI> <LI> Innate-like cytotoxicity of CD8<SUP>+</SUP> T cells is associated with liver injury in AHA </LI> </UL> </P> <P><B>Graphical Abstract</B></P> <P>[DISPLAY OMISSION]</P>
Kim, Cheol-Hong,Kim, Jong-Yeop,Hwang, Yong Il,Lee, Chang Youl,Choi, Jeong-Hee,Park, Yong-Bum,Jang, Seung-Hun,Woo, Heungjeong,Kim, Dong-Gyu,Lee, Myung Goo,Hyun, In-Gyu,Jung, Ki-Suck,Kim, Hyun Soo The Korean Academy of Tuberculosis and Respiratory 2014 Tuberculosis and Respiratory Diseases Vol.76 No.1
Background: Interferon-${\gamma}$ assays based on tuberculosis (TB)-specific antigens have been utilized for diagnosing and ruling out latent TB and active TB, but their utility is still limited for TB incidence countries. The aim of this study is to understand the clinical utility of enzyme-linked immunospot (ELISpot) assays among patients with clinically suspected TB and healthy adults in clinical practices and community-based settings. Methods: The ELISpot assays (T SPOT.TB, Oxford Immunotec, UK) were prospectively performed in 202 patients. After excluding those with indeterminate results, 196 were included for analysis: 41 were TB patients, 93 were non-TB patients, and 62 were healthy adults. Results: The sensitivity and negative predictive values of the T SPOT.TB assays for the diagnosis of TB were 87.8% and 89.1%, respectively, among patients with suspected TB. The agreement between the tuberculin skin test (10-mm cutoff) and the T SPOT.TB assay was 66.1% (kappa=0.335) in all participants and 80.0% (kappa=0.412) in TB patients. Among those without TB (n=155), a past history of TB and fibrotic TB scar on chest X-rays were significant factors that yielded positive T SPOT.TB results. There was a significant difference in the magnitude of T SPOT.TB spot counts between TB patients and non-TB patients or healthy adults. Conclusion: The T SPOT.TB assay appeared to be a useful test for the diagnostic exclusion of TB. A positive result, however, should be cautiously interpreted for potential positives among those without active TB in intermediate TB incidence areas.