횡문근 용해증이 동반된 원발성 갑상선기능 저하증 1예

김하영,조정구,박병현 圓光大學校 醫科學硏究所 2006 圓光醫科學 Vol.21 No.1

1996년과 1999년 경기지역 초등학교 학생들에서 유행성이하선염에 대한 면역도 조사

나병국,이주영,고운영,이진수,신구철,이주연,최보율,기모란,양병국,강춘,김우주,김지희 대한감염학회 2001 감염 Vol.33 No.3

Background : Although massive use of live attenuated mumps virus vaccines successfully reduced the incidence of mumps virus infection worldwide, mumps outbreaks have not been completely eliminated, even in vaccinated populations. In recent years, the incidence of mumps has been remarkably increased in Korea. This study was designed to evaluate the recent seroprevalence rate of mumps IgG among children in Kyonggi province at 1996 and 1999. Methods : Study population included students from 8 elementary schools in Kyonggi province. Serum samples were collected twice at 1996 and 1999 and tested for mumps-specific antibody by enzyme-linked immunosorbent assay (ELISA). We also conducted a questionnaire survey on the parents and collected the records including history of vaccination and mumps infection. Results : The seropositive rates against mumps were 89.47% and 89.74% at 1996 and 1999, respectively, and they were not significantly different when compared to age, sex, and region. Although the first vaccination rates were 92.17% and 92.25% at 1996 and 1999, respectively, the second vaccination rates were only 37.89% and 38.03% at 1996 and 1999, respectively. Infection rate showed no significant difference between vaccinated groups and nonvaccinated gropus. Seropositive rate of infected group was higher than that of noninfected group but it was not significantly different between the vaccinated and the nonvaccinated. Conclusions : This study showed the seropositive rate and vaccination against mumps in children. There were no significant relationships between vaccination and infection. Therefore, it seems likely that the vaccination is not fully protective against mumps infection. This study will be helpful for the establishment of guideline for prevention and treatment of mumps in Korea. (Korean J Infect Dis 33: 157∼164, 2001)

중학교 8학년 과학 「지구의 역사와 지각변동」 단원에서 정보통신기술(ICT) 활용 수업의 효과

정진우,문병찬,정재구,이미영 한국과학교육학회 2004 한국과학교육학회지 Vol.24 No.6

이 연구는 중학교 8학년 과학 '지구의 역사와 지각 변동' 단원에서 ICT 활용 수업 과정안을 개발ㆍ적용하여 ICT 활용 수업이 학생의 과학 탐구 능력과 과학에 관련된 정의적 특성에 미치는 효과를 알아보는 데 그 목적이 있다. 이 연구를 위해 충청남도에 소재한 D중학교 2학년 2개 학급을 선정하고 교수-학습 방법을 달리하여 약 6주간 수업하였다. 1개 학급은 실험집단으로 ICT수업 과정 안을 개발하여 ICT를 활용한 수업을 실시하였으며, 1개 학급은 통제집단으로 교과서 위주의 전통적 방법으로 수업 하였다. 학습을 하기 1주일 전에 두 집단을 대상으로 과학 탐구 능력과 과학에 관련된 정의적 특성에 대한 사전 검사를 실시하였으며, 수업이 끝난 뒤에 사후 검사를 실시하였다. 그 결과, ICT를 활용한 실험집단과 전통적 학습을 실시한 통제집단의 과학 탐구 능력 검사에서는 실험 집단에서 유의미한 차이가 나타났다. 또한, 과학에 관련된 정의적 특성에 대한 검사에서 실험집단에서 통계적으로 유의미한 차이가 나타나지는 않았지만, 3개의 과학에 관련된 특성 범위 중에서 흥미 범위에서는 통계적으로 유의미한 차이가 나타났다. 이는 ICT 활용 수업이 학생들의 과학에 관련된 정의적 특성에도 긍정적인 효과가 있음을 시사하는 것이다. The effects of learning using Information Communication Technology(ICT) on the students' scientific inquiry ability and science-related affective characteristics were analyzed in Earth History and Crust Movement units of science textbook for eighth graders. For this study, two classes of middle school second students in Chung-nam were selected and taught for six week under different teaching methods. One class is the test class taught with ICT applied teaching materials and the other class is the control class instructed by a conventional method. One week before the experiment, both classes were given tests on scientific inquiry ability and science-related affective characteristics, and they were tested again after the experiment. The results of scientific inquiry test showed statistically meaningful differences in the experimental class and the control class. The experimental class showed statistically meaningful difference in scientific inquiry test. Science-related affective characteristics test showed no statistically meaningful difference in the experimental class. Among three scientific science-related affective characteristics, especially the one fields of interests showed statistically meaningful differences which suggest that learning using ICT has a positive effect on the expanding of students' science-related affective characteristics.

성장호르몬과 프로락틴을 분비하는 뇌하수체 선종이 동반된 Albright증후군 1예

오효정,김용성,신진호,김하영,박병현,조정구 圓光大學校 醫科學硏究所 2005 圓光醫科學 Vol.20 No.1

다운 증후군과 동반된 그레이브스병 1예

노혜정,신진호,김하영,김용성,백승훈,박병현,조정구 圓光大學校 醫科學硏究所 2005 圓光醫科學 Vol.20 No.1

Original Articles : Amblyopia and Strabismus by Monocular Corneal Opacity Following Suspected Epidemic Keratoconjunctivitis in Infancy

( Byoung Young Gu ),( Jun Hyuk Son ),( Myung Mi Kim ) 대한안과학회 2011 Korean Journal of Ophthalmology Vol.25 No.4

Purpose: To identify the long term clinical course of amblyopia and strabismus that developed secondary to a monocular corneal opacity following suspected epidemic keratoconjunctivitis (EKC) in infancy. Methods: This was a retrospective study analyzing the medical records of seven patients, treated in our clinic, who were followed for more than five years. Results: Four patients in our clinic underwent a corneal ulcer treatment following suspected EKC. Each developed a monocular corneal opacity. Three patients with a chief complaint of corneal opacity were transferred to our clinic from other clinics. These patients had documented histories of treatment for EKC in infancy. All patients were treated with early occlusion therapy, but amblyopia persisted in four patients. Furthermore, all patients had strabismus and showed a significant reduction of stereoscopic vision. Conclusions: Although infants with EKC are not always cooperative, slit lamp examination should be performed as early as possible, and appropriate medical treatment should be performed, thus reducing the development of corneal opacity. Careful follow up should be regularly performed, and the occurrence of amblyopia or strabismus should be verified at an early stage using visual acuity or ocular alignment examination. Ophthalmologic treatments, including active occlusion therapy, should also be pursued.

Superior optical properties of homogeneous liquid crystal alignment on a tin (IV) oxide surface sequentially modulated via ion beam irradiation

Kang, Young-Gu,Park, Hong-Gyu,Kim, Hyung-Jun,Kim, Young-Hwan,Oh, Byeong-Yun,Kim, Byoung-Yong,Kim, Dai-Hyun,Seo, Dae-Shik The Optical Society 2010 Optics express Vol.18 No.21

<P>We first investigated the alignment characteristics of tin (IV) oxide (SnO(2)) thin films deposited by radio-frequency (RF) magnetron sputtering. This study demonstrates that liquid crystal (LC) molecules could be aligned homogeneously by controlling the Ion Beam (IB) irradiation energy densities. We also show that the pretilt angle of the LC molecules has a close relation with the surface energy. X-ray photoelectron spectroscopy (XPS) indicates that a non-stoichiometric SnO(2-x) surface converted by ion beam irradiation can horizontally align the LC molecules. The measured electro-optical (EO) characteristics showed high performance, comparable with those of rubbed and ion-beam irradiated polyimide (PI) layers.</P>

울산지역에서 주폐경기 ( Perimenopause ) 여성의 골다공증 유병률과 연관인자

김영일(Young Il Kim),박재후(Jae Hoo Park),이종수(Jong Soo Lee),김진우(Jin Woo Kim),양승오(Seoung Oh Yang),전대준(Dae Joon Jeon),김문찬(Mun Chan Kim),정태흠(Tae Heum Jeong),이윤구(Yoon Gu Lee),이병두(Byoung Doo Rhee) 대한내과학회 2002 대한내과학회지 Vol.62 No.1

N/A Background: Osteoporotic fractures pose a major public problem, not only in Western populations but also of increasing significance in Asian populations. However, most previous studies for the prevalence of osteoporosis in Korea were carried out from the data of hospitalized or out-patient based subjects, hospital staff, healthy volunteers and so forth. The purpose of present study was to evaluate the normative data of bone mineral density (BMD) in Korean young and perimenopausal women and to determine the prevalence and risk factors of low bone mass, including osteoporosis and osteopenia in a community- based population. Methods: In 1999, a baseline survey was carried out in the Dong-gu of Ulsan city, a urban area but located in seashore of southeastern Korea. The selected community sample of 3,822 inhabit ants (all were women aged 49-54 years) were chosen. We studied 1,629 women among them and 127 healthy women aged 20-35 years. BMD of lumbar spine and femur was measured using dual-energy X-ray absorptiometry. For analysis of risk fact ors, those were excluded who was the current or recent user of estrogen and who had osteoporosis related disease or unknown menopause due to previous hysterectomy. Thus, 1,020 subjects were analysed for the association of low BMD and risk factors. Significant determinants of BMD were investigated using univariate and multiple regression analysis. Results: When our young normal data were used, 9.8% for the lumbar spine and 1.4% for the femoral neck of our study population (n=1,629) were classified as osteoporosis. Among them, the menopausal status of above 1,020 subjects had independent association with low BMD (T-score<-1.0) of both lumbar spine (odds ratio=4.71 in postmenopause, p <0.001) and femoral neck (odds ratio=2.86 in postmenopause, p <0.001). In premenopausal women (n=507), weight and age of menarche were associated independently with low bone mass, including osteoporosis and osteopenia of both lumbar spine and femoral neck. In postmenopausal women (n=513), weight and duration since menopause were associated independently with low bone mass of both lumbar spine and femoral neck. Also, daily amount of calcium intake had significant association (regression coefficient =0.047; p <0.05) independently with BMD of femoral neck. Conclusion: The result s of this population-based study suggest that it is import ant to prevent bone loss and screen the BMD in women aged 49-54 years with menopause, low body weight, late menarche, prolonged duration since menopause, low calcium intake.(Korean J Med 62:11- 24, 2002)

거짓비늘증후군에서 혈청 호모시스테인 농도와 관상동맥심질환의 위험도 분석

구병영(Byoung Young Gu),추지희(Ji Hee Chu),임수호(Su Ho Lim),차순철(Soon Cheol Cha) 대한안과학회 2016 대한안과학회지 Vol.57 No.3

목적: 거짓비늘증후군 환자에서 혈청 호모시스테인 농도를 조사하여 관상동맥심질환의 위험도와 연관성을 알아보고자 하였다. 대상과 방법: 2013년 3월부터 2013년 9월까지 영남대학교병원 안과 외래를 방문한 거짓비늘증후군 환자 37명과 비슷한 연령대의 거짓비늘증후군이 없는 환자(대조군) 59명을 대상으로 전향적 연구를 시행하였다. 거짓비늘증후군 환자와 대조군에서 정맥혈을 채취하여 측정한 혈청 호모시스테인 농도를 비교 분석하였다. 프래밍햄 위험점수(Framingham risk score)를 이용하여 산출한 관상동맥심질환 10년 위험도를 두 군 간에 비교하였다. 아울러 혈청 호모시스테인 농도와 관상동맥심질환 10년 위험도 사이의 상관관계를 조사하였다. 결과: 거짓비늘증후군 환자의 평균 혈청 호모시스테인 농도는 13.3 ± 6.8 μmol/L였으며 대조군(10.0 ± 5.2 μmol/L)에 비하여 통계적으로 유의하게 높았다(p=0.009). 관상동맥심질환 10년 위험도가 20% 초과인 고위험군의 비율은 거짓비늘증후군 환자에서 21.4%로, 대조군의 4.4%에 비하여 통계적으로 유의하게 높았다(p=0.048). 거짓비늘증후군 환자와 대조군 전체에서, 혈청 호모시스테인 농도와 산출된 관상동맥심질환 10년 위험도 사이에는 양의 상관관계를 보였다(r=0.578, p<0.001). 결론: 거짓비늘증후군 환자에서 혈청 호모시스테인 농도가 높고, 관상동맥심질환 위험도가 큰 것으로 나타났다. 따라서 고호모시스테 인혈증을 보이는 거짓비늘증후군 환자에서 관상동맥심질환의 발생을 예방하기 위한 노력이 필요할 것으로 생각된다. Purpose: To investigate levels of serum homocysteine in patients with pseudoexfoliation syndrome and the association between serum homocysteine levels and risk of coronary heart disease. Methods: From March 2013 to September 2013, 37 patients with pseudoexfoliation syndrome and 59 age-matched patients(control group) were enrolled in this prospective study. Serum homocysteine levels were compared between the 2 groups. We compared the estimated 10-year risk of coronary heart disease based on Framingham risk score between the 2 groups. Additionally, we analyzed correlations between risk of coronary heart disease and serum homocysteine levels. Results: The mean homocysteine level of patients with pseudoexfoliation syndrome was significantly higher than the control group (13.3 ± 6.8 μmol/L vs. 10.0 ± 5.2 μmol/L, p = 0.009). The rate of high risk defined as a 10-year coronary heart disease risk >20% in the patients with pseudoexfoliation syndrome was significantly higher than in the control group (21.4% vs. 4.4%, p = 0.048). Correlation between serum homocysteine levels and estimated 10-year risk of coronary heart disease was statistically significant (r = 0.578, p < 0.001). Conclusions: Hyperhomocysteinemia and high risk of coronary heart disease were observed in patients with pseudoexfoliation syndrome. Therefore, we suggest efforts to prevent coronary heart disease in pseudoexfoliation syndrome patients with hyperhomocysteinemia are necessary.

Prevalence of severe fever with thrombocytopenia syndrome virus in ticks from Deogyusan National Park

Young Sun Jo,Jun Gu Kang,Jeong Byoung Chae,Yun Kyung Cho,Weon Hwa Jheong,Yong Kwan Kim,Ji Young Won,Joon Seok Chae 대한수의학회 2017 대한수의학회 학술대회발표집 Vol.2017 No.-