응급실에 내원한 국내 간질중첩증 소아의 발생율과 특성

신은주(Eun Ju Shin),황세희(Se Hee Hwang) 대한소아신경학회 2016 대한소아신경학회지 Vol.24 No.1

Purpose: Status epilepticus (SE) is the most common life-threatening neurological condition in childhood. To clarify the incidence and outcome, we have evaluated the epidemiological and clinical characteristics of SE patients in Korea. Methods: In evaluating data from the National Emergency Department Information System (NEDIS), we retrospectively analyzed patients, and classified them by age and sex distribution, body temperature, time on arrival, seasonal variation and treatment outcome. The patients were under 8 years old who visited 111 general hospital emergency rooms in Korea between 2007 and 2013. Results: There were 4,257 total patients enrolled in our study. The ratio of males to females was 1.11:1. The incidence of SE in Korean children was 14.5/100,000 in 2010, and the highest incidence was seen in patients 1 to 2 years old. We could not find a seasonal variation. Febrile patients with temperatures over 38 °C accounted for 1,901 patients(44.7%). Peak time on arrival was 6 p.m. to midnight for 1,301 patients (30.5%). 3,356 patients (78.8%) were admitted immediately for proper treatment, while 678 patients(15.9%) were allowed to go home after emergency treatment. Unfortunately, 4 patients (0.1%) died despite first aid. Conclusion: The most common age in SE is 1 to 2 years. Regarding the correlation of fever with SE, patients who exhibit fever accounted for almost half of the patients with SE. In our study, the mortality rate in emergency room was 0.1%. Therefore, anyone who is suspected to have SE should be immediately transferred to a general hospital with ICU facilities for intensive treatment under the direction of medical experts.

흰쥐 Kupffer 세포에 대한 Propofol의 작용

박세훈,지대림,성언기,김희선,송인환,박희영,김준수,이덕희,박대팔 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.43 No.4

Background: Propofol has an antioxidant capacity and can be used for ischemia-reperfusion injury of the liver. However, the effects of propofol on the Kupffer cells have not been establisked. Methods: Kupffer cells were isolated and cultured from male Sprague-Dawley rats. The effects of propofol on the Kupffer cells were evaluated by a phagocytosis assay, TNF-α gene expression, and superoxide anion release after administering propofol in different concentrations on the cultured Kuprrer cells. Results: The latex bead phagocytosis by the Kupffer cells was suppressed when the Kupffer cells were exposed to propofol irrespective of concentrations. Higher propofol concentrations decreased the loss of Kupffer cells after latex bead phagocytosis. Propofol induced TNF-α mRNA expression in the Kupffer cells, but the mRNA expression level after 50㎍/ml of propofol decreased. The pattern of TNF-α mRNA expression induced by propofol was different to that induced by LPS: TNF-α mRNA was expressed continuously in the propofol-treated cells until 16 hours after exposure to propofol, whereas the level of TNF-α mRNA expression induced by LPS was evident after 2 hours and was not found thereafter. TNF-α production after propofol treatment was not higher than that of the control. Formazan presipitation did not show any qualitative differences between cells untreated or treated with propofol concentrations of 0.5, 5.0, and 50 ㎍/ml. Conclusions: These results showed that propofol might inhibit Kupffer cells. This suggests that propofol and be used for patients with ischemia-reperfusion injury of the liver. (Korean J Anesthesiol 2002; 43: 475~484)

동·서양 고전에 나타난 도덕적 통념에 관한 비판적 해석 -『논어』와 『에우티프론』에 나타난 아버지를 고발한 아들의 사례를 중심으로-

임명희 ( Lim Myung Hee ),김세원 ( Kim Se Won ) 동양철학연구회 2017 東洋哲學硏究 Vol.89 No.-

본 논문은 동서양의 고전 문헌에서 도덕적 통념에 관한 문제가 어떻게 다루어졌는지 고찰한 것이다. 이를 위해 『논어』에 나타난 `곧음(直)`에 관한 공자와 제자들의 대화, 『에우티프론』에 나타난 `경건함(?σιον)`에 관한 소크라테스와 에우티프론의 대화를 각각 분석하고, 그 철학적 함의를 검토하였다. 이를 통해 본 논문은, 공자와 소크라테스가 특정 도덕적 딜레마나 그것의 해결책 또는 특정 도덕관념에 대한 정의 자체에 관심이 있었다기보다, 독단적 자기 확신 또는 도덕적 통념에 관한 비판적 해석에 주안점을 두고 있었다는 것을 주장하였다. 결론적으로, 이들 철학자들은 아버지를 고발한 아들이라는 사례를 통해 우리의 삶에서 도덕적 믿음에 대한 반성적 태도가 중요함을 강조하며, 그 과정은 타자와의 대화를 수반한다는 점을 보여주고자 한 것이라 볼 수 있다. The aim of this study is to examine an issue of moral beliefs and moral conceptions in the Eastern and Western Classics. This paper focuses on the texts with one specific common material. That is the son who accused the father in the Analects(Lunyu) and the Plato`s Euthyphron. Confucius has a conversation with his follower about `Zhi(直)` and Socrates makes dialectical arguments with Euthyphron about a definition of `piety(to hosion)`. The philosophers critically examine opinions of the opposing parties to support the accusation. Other papers studied on aspects of moral dilemma(the private or the public, Physis and Nomos) or relation of religion and philosophy. But the important problem is relation between rightness(or justice) and honesty. In conclusion, this paper illuminates that the philosophers emphasize personal moral beliefs and their reflective attitudes toward one` own and lives, rather than the dilemma`s solution or the definition of moral ideas per se. Also, it is necessarily that the reflective courses involve a conversation with others.

Association between Socioeconomic Status and Altered Appearance Distress, Body Image, and Quality of Life Among Breast Cancer Patients

Chang, Oliver,Choi, Eun-Kyung,Kim, Im-Ryung,Nam, Seok-Jin,Lee, Jeong Eon,Lee, Se Kyung,Im, Young-Hyuck,Park, Yeon Hee,Cho, Juhee Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20

Background: Breast cancer patients experience a variety of altered appearance - such as loss or disfigurement of breasts, discolored skin, and hair loss - which result in psychological distress that affect their quality of life. This study aims to evaluate the impact of socioeconomic status on the altered appearance distress, body image, and quality of life among Korean breast cancer patients. Materials and Methods: A cross-sectional survey was conducted at advocacy events held at 16 different hospitals in Korea. Subjects were eligible to participate if they were 18 years of age or older, had a histologically confirmed diagnosis of breast cancer, had no evidence of recurrence or metastasis, and had no psychological problems at the time of the survey. Employment status, marital status, education, and income were assessed for patient socioeconomic status. Altered appearance distress was measured using the NCI's cancer treatment side effects scale; body image and quality of life were measured by the EORTC QLC-C30 and BR23. Means and standard deviations of each outcome were compared by socioeconomic status and multivariate linear regression models for evaluating the association between socioeconomic status and altered appearance distress, body image, and quality of life. Results: A total of 126 breast cancer patients participated in the study; the mean age of participants was 47.7 (SD=8.4). Of the total, 83.2% were married, 85.6% received more than high school education, 35.2% were employed, and 41% had more than $3000 in monthly household income. About 46% had mastectomy, and over 30% were receiving either chemotherapy or radiation therapy at the time of the survey. With fully adjusted models, the employed patients had significantly higher altered appearance distress (1.80 vs 1.48; p<0.05) and poorer body image (36.63 vs 51.69; p<0.05) compared to the patients who were unemployed. Higher education (10.58, standard error (SE)=7.63) and family income (12.88, SE=5.08) was positively associated with better body image after adjusting for age, disease stage at diagnosis, current treatment status, and breast surgery type. Similarly, patients who were married and who had higher education had better quality of life were statistically significant in the multivariate models. Conclusions: Socioeconomic status is significantly associated with altered appearance distress, body image, and quality of life in Korean women with breast cancer. Patients who suffer from altered appearance distress or lower body image are much more likely to experience psychosocial, physical, and functional problems than women who do not, therefore health care providers should be aware of the changes and distresses that these breast cancer patients go through and provide specific information and psychosocial support to socioeconomically more vulnerable patients.

특수 언어발달 장애 환아의 임상 및음향음성학적 특성연구

김연희,박세훈,신용일,김찬양,김현기,김정수 大韓再活醫學會 2000 Annals of Rehabilitation Medicine Vol.24 No.1

8개 압저항 브릿지구조를 이용한 저 타축 감도 실리콘 가속도센서

徐熙敦,李榮泰,崔世崑 경북대학교 센서기술연구소 1995 센서技術學術大會論文集 Vol.6 No.1

A low off-axis sensitivity piezoresistive accelerometer has been presented. The off-axis sensitivity was reduced by arrangement of eight piezoresistors on two the beams. The structure and stress distribution of the accelerometer was optimized using FEM(finite element modeling) simulation. The dependence of sensitivity and resonance frequency were also simulated as a function of the beam length for a constant overall size(2000μm). Accurate thickness control of the beams was realized by the etch-stop techonology using SDB(silicon direct bonding) wafer SiO_(2) layer and RIE(reative ion etching) method. This method is relatively simple and very useful for fabrication of accelerometer.

분절간 척추경 나사 고정과 척추전이법을 이용한 특발성 척추 측만증의 치료

석세일,김진혁,이상민,정의룡,김성수,이정희,박준석 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.2

Objective : To report the clinical result of segmental pedicle screw fixation and translation technique in surgical correction of idiopathic scoliosis. Methods and materials : Ten idiopathic scoliosis. patients treated with segmental pedicle screw fixation and translation technique were analyzed retrospectively. The mean follow-up interval was 23.8months, with a minimum of 12 months. Eighteen structural curves were fused in one double curves(King type Ⅰ), seven double thoracic curve(King type Ⅴ) and two thoracolumbar curve. Deformity correction, apical vertebral rotation(AVR), apical vertebral translation(AVT), trunk balance, shoulder balance and complications were evaluated. Result : The structural curve was corrected from 47.4±10.6° to 20.3±5.9° at 1week after surgery and 55.6±14.1° at latest follow-up. AVR was corrected from 2.06±0.4 to 0.94±0.41 at 1week after surgery and latest follow-up. AVT was improved from 25±15.7㎜ to 11.5±7.3㎜ at 1week after surgery and 12.3±7.3㎜ at latest follow-up. There were no trunk imbalance(less than 10㎜ distance from C7 plumb line), no shoulder imbalance(less than 10㎜ shoulder height difference) and no screw related complications. Conclusions : The segmental pedicle screw fixation and translation technique is an effective method in treating for idiopathic scoliosis.

상악 측절치의 치내치에 대한 증례보고 : REPORT OF 2 CASES

윤석희,이재천,김영재,장기택,한세현,김종철 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.3

치내치(dens invaginatus)는 치아 발생 과정 중 경조직이 석회화되기 전에 법랑질 상피가 함입되어 생기는 치아 기형이다. 치내치는 함입된 정도에 따라다양한 형태학적 변이를 보이는데 이러한 기형은 미생물이 침입할 수 있는 통로가 될 수 있어 치수조직의 괴사와 치근단 농양 또는 치은 농양의 원인이 된다. 이러한 경우 근고나의 복잡한 해부학적 형태 때문에 근관 치료가 매우 어렵다. 본 증례는 상악 좌측 측절치의 동통을 주소로 내원한 두 명의 환아들에 관한 것이다. 첫 번째 증례는 수산화 칼슘제재를 이용한 근관치료를 시행하여 양호한 결과를 얻었고 두 번째 증례는 치아를 발거하였다. 발거된 치아는 미세전산화 단층촬영을 이용하여 해부학적 형태를 살펴보았기에 보고하는 바이다. Dens invaginatus is a malformation of tooth resulting from an infolding of the enamel epithelium during tooth development. This malformation shows a broad spectrum of morphologic variations. This invagination frequently allows the entry of irritants and microorganism, which usually lead to necrosis of the adjacent pulp tissue and then to periapical or periodontal abscess. Root canal treatment of such tooth is often difficult because of the unusual form and complicated pulpal space. This article reports 2 cases of dens invaginatus in maxillary lateral incisors. The first case was successfully treated with Ca(OH)₂. In the second case, involved tooth was extracted and this extracted tooth was observed using the micro-computed tomography.

노즐 직경이 충돌제트에 의하여 열전달에 미치는 영향

이대희,원세열,이영민,조헌노 인제대학교 1999 仁濟論叢 Vol.14 No.3

본 연구는 축대칭 난류원형제트가 평판에 충돌하는 경우에 노즐직경이 국소 Nusselt 수 분포에 미치는 영향을 연구하였다. 노즐출구에서의 유동은 완전 발달된 속도형상을 지니고 있다. 그리고, 금박막이 된 Intrex를 사용하여 평판에는 등열유속 경계조건을 형성시켰다 또한, 액정은 평판의 벽면온도를 측정하기 위하여 사용하였다. 실험시 Reynolds 수는 Re=23,000으로 고정하였으며, 노즐과 평판사이의 거리는 L/d=2~14 까지, 노즐 직경은 d=1.36, 2.16, 3.40으로 변화시켰다. 실험결과 정체점과 정체점 영역에서의 Nusselt 수는 노즐 직경이 증가함에 따라 증가함을 알았다. The effect of nozzle diameter on the local Nusselt number distributions has been investigated for an axisymmetric turbulent jet impinging on the flat Plate surface. The flow at the nozzle exit has a fully developed velocity profile. A uniform heat flux boundary condition at the plate surface was created using gold film Intrex. Liquid Crystal was used to measure the plate surface temperature. The experiments were made for the jet Reynolds number (Re) 23,000, the dimensionless nozzle to surface distance (L/d) from 2 to 14., and the nozzle diameter (d) from 1.36 to 3.40 cm. The results show that the Nusselt number at and near the stagnation point increase with an increasing value of the nozzle diameter.

콩 단백질/펙틴/몬모릴로나이트 나노복합 필름의 특성 및 산소 투과도 연구

정세환,김성철,조규순,신용섭,장상희,홍기헌,이태진,신부영 嶺南大學校 工業技術硏究所 2004 工業技術硏究所論文集 Vol.32 No.2

In this study, Mechanical property, thermal property, watervapor, and oxygen permeability of biodegradable Soy protein/Pectin-montmorillonite nanocomposite, prepared with Na^(+)-MMT, have been studied. X-ray diffraction and TEM experiments an polymer/silicate composite samples demonstrated that the intercalation of polymer chains leads to increase in the spacing between silicate layers. In addition, it were found that the intercalated Soy protein/Pectin/montmorillonite nanocomposite were prepared. It was found that the addition of only a small of clay was enough to improve the thermal stability and mechanical property of Soy protein/Pectin/montmorillonite nanocomposite. watervapor of Soy protein/Pectin/montmorillonite nanocomposite was generally lower than that of Soy protein/Pectin. oxygen permeability of Soy protein/Pectin/montmorillonite nanocomposite was generally lower than that of Soy protein/Pectin.