Steps We Have Taken and Steps We Must Take

장혜정,김정아 대한의료정보학회 2016 Healthcare Informatics Research Vol.22 No.2

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장용정 Omeprazole 정제와 캅셀제의 액제화 투여 방법의 용출시험

장혜정,이숙향 한국임상약학회 2001 한국임상약학회지 Vol.11 No.1

Omeprazole is usually administered as encapsulated enteric-coated granules and enteric-coated tablets because of its acid-labile nature. For children and patients who can not swallow, it can be mixed with water or other liquid after a capsule is opened or a tablet is crushed. This study was performed to compare omeprazole liquid formulations of tablet and capsule Omeprazole 20 mg capsule containing enteric coated granules was opened and 20 mg entric-coated tablet was ground to be mixed with sodium bicarbonate solution, orange juice or water. Each liquid formulation was poured into dissolution tester, mixed with first solution (artificial gastric juice; pH 1.2) for two hours, then with second solution (artifical enteric juice; pH 6.8) for thirty minutes. pH was measured periodically for two and half hours. Samples were drawn periodically, mixed with lansoprazole as an internal standard, and injected to HPLC. As results, pH of sodium bicarbonate solution of omeprazole was significantly higher than that of orange juice or water in first solution (6.2-7.4 vs. 1.2, p<0.005). At 150 min, concentrations of omeprazole in three diluents with granules and in sodium bicarbonate solution of tablet powder sustained significantly higher than in other solution of tablet powder (p<0.001). In conclusion, enteric-coated granules from capsule with three diluents and powder from tablet in sodium bicarbonate solution was stable during dissolution test, which would be appropriate and recommended for patient who can not swallow solid preparations.

Chemiluminescent Detection of Tear Glucose on Paper Microfluidic Devices

장혜정,노혜란 한국고분자학회 2015 Macromolecular Research Vol.23 No.5

Effect of various shaped magnesium hydroxide particles on mechanical and biological properties of poly(lactic-co-glycolic acid) composites

장혜정,박성빈,Tarek M. Bedair,오민규,안동준,박우람,정윤기,한동근 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.59 No.-

Five different shapes of magnesium hydroxide (Mg(OH)2) particles (Plate-S, Plate-N, Disk, Whisker, and Fiber) were synthesized and added to biopolymer (i.e., Poly(lactic-co-glycolic acid) (PLGA)) composite to improve their mechanical and biological properties. The PLGA composite films including Mg(OH)2 particles were prepared by a solvent casting method. Their mechanical and biological properties were compared according to the composites containing different shapes of Mg(OH)2 particles. Among them, the fiber shape of Mg(OH)2 provided the highest mechanical strength, and anti-inflammation and anti-bacterial activity to PLGA films among other forms. This study demonstrated a new strategy for the design of biomaterials by controlling the form of inorganic additives.

포스터 전시 발표 순서 : 혈액종양 ; 동종조혈모세포이식 후 유방과 자궁에 녹색종으로 발현한 백혈병 1례 (초)

장혜정,김인호,윤성수,박선양,김병국 대한내과학회 2008 대한내과학회지 Vol.75 No.1S

대학병원에 입원한 급성 뇌졸중 환자의 진료비 결정요인: 뇌내출혈과 뇌경색의 비교

장혜정,윤성상,권영대 대한신경과학회 2009 대한신경과학회지 Vol.27 No.3

Background: Intracerebral hemorrhage (ICH) and cerebral infarction, which are two types of stroke, have different properties in terms of patient characteristics and hospital resource utilization. The two stroke types were evaluated in the present study with respect to the associated estimated inpatient charges, and their significant determinants. Methods: The data of 497 stroke inpatients were collected from two academic hospitals in the year 2000~2001. The patients’ demographic and clinical information were investigated retrospectively through medical records, and their payment data were extracted through the hospitals’ information systems. The two types of stroke patient (i.e., ICH and cerebral infarction) were compared in terms of their demographic and clinical characteristics, and healthcare utilization. Multiple regression models were developed to examine the influence of demographic and clinical factors on inpatient charges. Results: The mean length of hospital stay was 22.4 days for ICH patients and 18.3 days for those with cerebral infarction; the total inpatient charges were 5,777 and 3,908 thousand Korean won, respectively. While stroke severity, intensive care unit admission, surgery, and death were significant factors on inpatient charges for ICH patients (R2=0.426), additional factors such as diabetes, hospital, and department of care were significant for cerebral infarction patients (R2=0.342). Conclusions: The inpatient charges and their determinants differed between ICH and cerebral infarction. However, the length of hospital stay was found to be the most significant determinant of inpatient charges for both stroke types; stroke severity was also important with regard to the estimation of inpatient charges.

소비자 특성별 건강정보 접근 방법

장혜정,심재선,김윤 대한의료정보학회 2004 Healthcare Informatics Research Vol.10 No.4

Objective : This study investigates consumers' choice regarding source of health information. Specifically, the relationships between consumers' socioeconomic characteristics, health status, attitude to health, information needs and source of health information were explored. Methods : Type of health information sources includes web-based, health professional, and mass-media types. Structured questionnaires were completed by 1,189 consumers through a telephone survey, and 622(52.3 %) responses were included in analysis. Results : A key finding was the significant difference for accessing health information by customer's characteristics, although the strong preference was shown in web-based resource. Accessing channels were different by consumer's needs of health information and attitude to health as well as consumer's age, job, education, and economic status. Conclusion : Consumer behaviors are likely to optimize physical and psychosocial health potentials through health information. Despite a growing number of available web-based health information resources, consumers continue to face a variety of barriers as they attempt to access these resources. Meeting consumer's needs for health information is an important role for all providers of health information.

중소병원 고객 추천에 영향을 미치는 웹사이트 속성

장혜정,서경화,정민아,이지현 대한의료정보학회 2006 Healthcare Informatics Research Vol.12 No.3

본 연구는 웹사이트를 운영하고 있거나 향후 운영할 계획을 가지고 있는 중소병원을 대상으로 웹사이트 운영 시 고려해야할 속성으로 탐색용이성과 디자인뿐만 아니라 정보내용의 중요성을 강조하고 있다. 웹사이트는 병원의 이미지를 나타내는 한 도구가 될 수 있으므로 탐색용이성을 고려하여 사이트를 구성하고, 심미적이고 유희적인 요소를 고려하여 디자인해야 할 것이며, 무엇보다 환자들의 요구도를 고려하여 고객의 의료기관 방문 및 건강에 도움이 될 만한 의학상식 및 정보를 충분히 제공해야 할 것이다. 본 연구의 결과는 현재 중소병원이 직면하고 있는 경영상의 문제점을 해결하기 위한 하나의 전략방안으로서 병원에서의 고객 확보를 위한 웹사이트의 이용 가능성을 제시하고 있으며, 향후 웹사이트 운영전략 및 경영환경 개선책 수립에 참고자료로 활용될 수 있을 것으로 기대한다.

병원의 전략경영을 위한 정보시스템의 통합적 접근

장혜정 대한의료정보학회 2007 Healthcare Informatics Research Vol.13 No.3

With the institutional and market changes in hospitals, strategic management has become increasingly important. Strategic managerial innovations can have impact on market pioneering and hospital performance, enabling better customer satisfaction, productivity improvement, and quality management. Hospital Information systems also require strategic planning to improve functionality in all aspects. This article reviewed the concept of strategic management and strategic information system (SIS), and summarized a framework for developing SIS for hospitals. The SIS formulation process consists of two interrelated phases: organizational analysis and SIS development. The first phase involves an analysis of the hospital’s current position and the development of the hospital’s vision and goals. The second phase incorporates three activities: SIS goals assessment, strategic information requirements analysis (SIRA), and SIS implementation planning. In particular, in SIRA, four dimensions of SIS and their interrelationships between dimensions would permit an organization to specify the strategic information needs within a hospital. Hospitals that integrate this framework with other aspects of their own hospital management information systems cope more effectively with the rapid changes and challenges encountered in today's health service industry. (Journal of Korean Society of Medical Informatics 13-3, 189-196, 2007)

Application of the Extended Technology Acceptance Model to Picture Archiving and Communication Systems in Dental Hospitals

장혜정 대한의료정보학회 2009 Healthcare Informatics Research Vol.15 No.3

Objective: With the rapid growth of picture archiving and communication systems (PACS) in the healthcare industry, this article describes the users’ satisfaction with PACS by employing functional PACS features and the two concepts of perceived ease-of-use (PEOU) and perceived usefulness (PU), based on the extended technology acceptance model (TAM). Methods: A cross-sectional survey was conducted with dentists in 25 dental hospitals which were cluster sampled from the national registry of 132 dental hospitals. Of the 204 respondents (response rate 81.6%), the data of 159 PACS users were analyzed using the structural equation modeling method. Results: The fitted model showed significant relations between the technical components and the TAM variables, via the following three significant paths: hardware to PEOU, and software to PEOU and also to PU. Moreover, the critical path of TAM variables was observed: PEOU→PU→SAT. Therefore, the model produced three significant routes: hardware→PEOU→PU→SAT, software→PU→SAT, and software→PEOU→PU→SAT. Conclusion: Contrary to expectations, the direct effect of PEOU on user satisfaction was not significant. The final model provided critical paths from technical components to user satisfaction, by utilizing PEOU and PU as intermediary, latent factors.