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내경계막 제거술 후 발생한 활꼴모양의 망막신경섬유층의 부종
이시형,이성진,최경식,Si Hyung Lee,Sung Jin Lee,Kyung Seek Choi 대한안과학회 2014 대한안과학회지 Vol.55 No.4
Purpose: To evaluate the cause of dark arcuate striae observed in infrared photographs in idiopathic epiretinal membrane (ERM) and macular hole patients after internal limiting membrane (ILM) peeling. Methods: Forty patients (41 eyes) of idiopathic ERM and macular hole who underwent trans pars plana vitrectomy with ILM peeling and gas tamponade were included in the present study. The best corrected visual acuity (BCVA) was recorded at preoperative and postoperative 6 months. Infrared (IR) photography with spectral domain optical coherence tomography (SD-OCT) were obtained at preoperative and postoperative 1 week, 1 month, 3 months, and 6 months. When abnormal findings were visible on IR photographs, additional SD-OCT was performed at the corresponding sites. Results: Of 40 patients, 4 patients demonstrated dark striae extending from the optic nerve to near macular area in IR photographs at 1 week postoperatively. SD-OCT images of the dark striae region revealed the swelling of retinal nerve fiber layer (RNFL). At postoperative 6 months, however, RNFL swelling previously observed subsided in all 4 cases, while temporal retinal thinning and dimples were observed in 3 cases. The preoperative and postoperative BCVA did not show any statistical difference between the patients with the RNFL swelling and the patients without the swelling. Conclusions: Swelling of RNFL may occur in idiopathic ERM and macular hole patients after pars plana vitrectomy and ILM peeling, which may present as dark striae in IR photographs. J Korean Ophthalmol Soc 2014;55(4):534-540
이시형,김진만,김명희,Lee, Si-Hyung,Kim, Jin-Man,Kim, Myung-Hee 한국육가공협회 2008 肉加工 Vol.35 No.-
육회는 가열처리 없이 섭취하기 때문에 다양한 미생물에 노출될 수 있다. 본 연구에서는 대구 지역의 육회 전문점 5곳을 선정하여 미생물 분포를 조사하였다. 식당에서 판매되고 있는 조리된 육회를 식품공전 방법에 따라 중온성균수와 대장균군수를 측정하였고 식품중에 검출되어서는 아니되는 병원성 세균인 Salmonella spp., Staph. aureus, E. coli O157:H7, L. monocytogenes의 검출 유무를 조사하였다. 조사 결과, 육회에는 중온성균이 6.6$\times$103-2.7$\times$105 CFU/g, 대장균군이 8.9$\times$101-2.1$\times$105 CFU/g으로 분포되었다. 모든 육회 시료에서 Salmonella spp., E.coli O157:H7, L. monocytogenes은 검출되지 않았으나 한 시료에서 Staph. aureus가 검출되었다. 이외 임상학적으로 중요한 미생물들이 동정되었다. 가열과정 없이 바로 섭취하는 육회는 원료의 생산 및 조리과정에서 엄격한 위생 감독이 요구된다. People can be exposed to various microorganisms when they eat yukae (seasoned raw meat) because yukae is eaten raw. The purpose of this study was to find out microbial distribution in yukae. In this experiment, 5 restaurants serving yukae were chosen in Daegu area. Mesophilic microorganisms and coliforms were measured by Korean Food Standards Codex. Analyses of Salmonella spp., Listeria monocytogenes, Staphylococcus aureus and Escherichia coli O157:H7 were conducted. As results, mesophilic microorganisms ranged 6.6$\times$103-2.7$\times$105 CFU/g and coliforms ranged 8.9$\times$101-2.1$\times$105 CFU/g. Salmonella spp., Listeria monocytogenes and Escherichia coli O157:H7 were not detected in all 5 samples. However, Staphylococcus aureus was detected in 1 sample out of 5 samples. Hygiene practice during production, processing and cooking process is required.
사회공포증 경과중 타 정신질환이 발병한 환자들에 대한 연구
이시형,신영철,양상중,Lee, Si-Hyung,Shin, Young-Chul,Yang, Sang-Joong 한국정신신체의학회 1996 정신신체의학 Vol.4 No.1
We have studied 16 patients diagnosed of social phobia among the hospitalized patients for 1 year, from September 1994 to August 1995, to evaluate whether serial phobic symptoms are the prodromal symptoms of the other psychiatric disorder or concomitant disorder. The results were as follows; 1) In the subject of this study, the mean age of onset of social phobic symptoms was 17.3, and the mean age of inital hospital visit was 27.4. 2) The proportion of offensive type was higher than the simple type : 7 cases of the subjects classified as simple type, 9 cases as offensive type. 3) According to the type of social phobia, they developed different type of psychiatric disorder. Majority of patients with simple type had final diagnosis of mood disorder. Patients with offensive type had schizophrenia spectrum disorder, such as schizophrenia, delusional disorder, and schizophrenia, personality disorder. 4) Social phobic symptoms have taken various courses according to the final diagnosis. In the patients who developed major depression and delusional disorder, social phobic symptoms have not been changed during the course. Patients with the final diagnosis of schizophrenia and schizotypal personality disorder have showed various social phobic symptoms. In the patients with the final diagnosis of bipolar disorder, their social phobic symptoms disappeared with improvement of depression.
이시형,김민경,김도영,신한승 한국식품과학회 2021 Food Science and Biotechnology Vol.30 No.7
This study analyzed four polycyclic aromatichydrocarbons (PAHs) from frequently consumed homemeal replacement (HMR) products in Korea and evaluatedtheir chemical analysis methods. The PAHs investigatedwere benzo[a]anthracene, chrysene, benzo[b]fluorantheneand benzo[a]pyrene. Chrysene-d12 and benzo[a]pyrened12served as internal standards. The sample was dissolvedin dichloromethane before extraction. Liquid–liquidextraction, microwave extraction, alkali digestion and GC–MS were used for analysis. Method validation was conductedon four matrices: fatty solid, fatty liquid, non-fattyliquid, non-fatty solid. Linear correlation coefficients (R2)were all above 0.99 and accuracy ranged from 80.03 to119.65%. The LOD and LOQ were in the range of0.03–0.15 and 0.09–0.44 lg/kg, respectively. The recoveriesvaried from 81.09 to 116.42% and precision rangedfrom 0.07 to 10.73% in both intraday and interday analysis. All concentrations of total PAHs from HMR products weredetected at relatively low concentration. This study couldprovide the PAHs content from HMR products in Korea.
202종(種) 한약재(韓藥材)의 $IFN-{\gamma}$ 분비조절에 관한 비교연구
이시형,강미숙,최유경,전찬용,박종형,김동우,Rhee, See-Hyung,Kang, Mi-Suk,Choi, You-Kyung,Jun, Chan-Yong,Park, Chong-Hyeong,Kim, Dong-Woo 대한한방내과학회 2006 大韓韓方內科學會誌 Vol.27 No.2
Objects : This study has been carried out to assess the effects of the variable herbs on $IFN-{\gamma}$ secretion in the mouse spleen cell. Methods : 202 kinds of herb extracts were used to evaluate the $IFN-{\gamma}$ secretory distinction by each $1{\mu}g/ml$ and $10{\mu}g/ml$ density of water. All experimental herbs were grouped by oriental herbalogical method. But each herb had its independent variables. Results : The secretions increased in 20% of all herbal water. The density differences also make different effects on the secretion of $IFN-{\gamma}$. The secretion of IFN-${\gamma}$ inclosed in some kinds of herbs of IFN-${\gamma}$. It has representatively increased in Imperaetae Rhizoma(白茅根) of $1{\mu}g/ml$ and Notopterygii Rhizoma(羌活)of $10{\mu}g/ml$. $IFN-{\gamma}$ incresed in 12 kinds of heybs of both densities. The secretion of $IFN-{\gamma}$ decreased in some kinds of herbs of $IFN-{\gamma}$. It has representatively decreased in Moutan Radicis Cortex(蘇丹皮) of $1{\mu}g/ml$ and Angelicae Radix(富歸尾) of $10{\mu}g/ml$. $IFN-{\gamma}$ decreased in 18 kinds of herbs of both densities. In t oriental herb group, The secretion of $IFN-{\gamma}$ increased in Bang-Hyang-Hwa-Sup group(芳香化濕藥), He-Pyo group(解表藥), I-Su-Sam-SuP group(利水渗) The secretion of $IFN-{\gamma}$ decreased in Gu-Chung group(驅蟲藥), An-Sin group(安神藥). Su-Sap group(收澁) On-Li group(溫裏藥), I-Gi group(利氣藥). Conclusions : The result of this study will not only broaden applications of oriental medicine to biological therapy, but also form the basis of oriental medical therapy to find out the meaning of oriental classification.