Preparation of acryl syrup via photo-polymerization

손지희,이재관 한국고분자학회 2012 한국고분자학회 학술대회 연구논문 초록집 Vol.2012 No.10

무궁화 품종 '난파'의 효율적인 재분화 체계 확립

손지희,선현진,강홍규,서석철,이효연,Son, Ji-Hi,Sun, Hyeon-Jin,Kang, Hong-Gyu,Suh, Seok-Chul,Lee, Hyo-Yeon 한국식물생명공학회 2019 식물생명공학회지 Vol.46 No.4

Hibiscus syriacus L., the national flower of Korea, is a commonly grown ornamental species found in parks, gardens and along roadsides in Korea. This study sought to establish a plant regeneration system of H. syriacus 'Nanpa' using mature leaves as an explant. Sterilized mature leaf explants were cultured on modified MS medium with combinations of NAA and BAP at various concentrations for 6 weeks. Among the various media evaluated, modified MS media containing 0.46 mg/L NAA and 0.5 mg/L BAP (CI-1) or 0.92 mg/L NAA and 1 mg/L BAP (CI-4) were the most effective for callus formation. Whitish-yellow calluses were observed on CI-1 medium, while green calluses formed on CI-4 medium. The whitish-yellow callus derived from CI-1 medium showed a higher frequency of shoot induction than the green callus derived from CI-4 on modified MS medium containing 0.5 mg/L BAP. Among the various media evaluated in this study, modified MS medium containing 0.46 mg/L NAA and 0.5 mg/L BAP was the most optimal for shoot-forming callus production. Our findings show that mature leaves of H. syriacus 'Nanpa' can be used for in vitro plant regeneration, and the regeneration system described here may be a powerful tool for molecular breeding of H. syriacus 'Nanpa' in the future.

Cowden Disease: Case Report and Review of the Literature

손지희,정보영,정민재,최영원,김혜원,박천욱 대한피부과학회 2019 Annals of Dermatology Vol.31 No.3

Cowden’s disease is a rare autosomal dominant, multiple hamartoma syndrome with characteristic mucocutaneous lesions. It is associated with abnormalities of the breast, thyroid, and gastrointestinal tract; and is characterized by multiple hamartomas in the gastrointestinal tract and mucocutaneous lesions such as trichilemmomas, oral papillomatosis, facial papules, and acral keratosis. A 21-year-old male patient presented with erythematous facial papules, oral mucosal papillomatosis, and punctate palmoplantar hyperkeratosis indicating a definite case of Cowden’s disease. This disease derives from variable expression resulting from a mutation in the PTEN gene. Gastrointestinal endoscopy and colonoscopy revealed multiple hamartomas in the stomach and colon. On thyroid ultrasonography, several probable benign nodules were noted in the right thyroid gland. He had no pertinent family history and no other systemic findings. Further regular laboratory and image studies will be planned for our patient, as well as his family members. Sporadic Cowden’s disease is rarely observed. Herein, we report a case of Cowden’s disease without known family history. Dermatologists should be aware of the possibility of Cowden syndrome based on its several dermatologic findings.

Clinical Features of Atopic Dermatitis in Adults Are Different according to Onset

손지희,정보영,김혜원,박천욱 대한의학회 2017 Journal of Korean medical science Vol.32 No.8

Few studies of atopic dermatitis (AD) in adult patients have evaluated differences in clinical features of AD according to onset age. We aimed to characterize the clinical features of AD in adult patients according to age of onset. Subjects with AD outpatient visiting the Department of Dermatology at Kangnam Sacred Heart Hospital were recruited for this study. A dermatologist conducted clinical evaluation, a survey of demographics, and onset of AD-associated signs and symptoms for each participant. Total immunoglobulin E (IgE) was also tested. A total of 280 adult AD patients were enrolled, among which 232 patients (82.86%) showed pre-adult-onset (age < 18 years) and 48 patients (17.14%) had adult-onset (age ≥ 18 years) of AD. There were significant differences between the 2 groups in the area of initial involvement (P = 0.017) and in treatment history (P = 0.010). Interestingly, patients with body mass index (BMI) ≥ 25 showed significantly higher Eczema Area and Severity Index (EASI) scores than did patients with BMI < 25 in the pre-adult-onset adult AD group (P = 0.048). On the other hand, there were no significant differences in sex, family history, BMI, EASI, and total IgE between patients with pre-adult-onset AD and patients with adult-onset AD. Our findings suggest that, even though many common features exist, there are significant differences between the clinical characteristics of pre-adult-onset and adult-onset AD subgroups, in adult patients with AD.

설진의 표준화를 위한 제언 : 설태 후박의 진단기준을 중심으로

손지희,김진성,박재우,류봉하,Son, Ji-Hee,Kim, Jin-Sung,Park, Jae-Woo,Ryu, Bong-Ha 대한한방내과학회 2012 大韓韓方內科學會誌 Vol.33 No.1

Background : In oriental medicine, the status of the tongue is an important indicator to diagnose the condition of one's health, such as physiological and the clinicopathological changes of internal organs. A tongue diagnosis is not only convenient but also non-invasive, and therefore widely used in Oriental medicine. However, the tongue diagnosis is greatly affected by examination circumstances, patient's posture, and doctor's diagnosis criteria. Objectives : This study was designed to assure the necessity for standardization of tongue diagnosis based on diagnostic criteria of tongue coating thickness (TCT). Methods : Thirty tongue photographs were acquired and analyzed by digital tongue diagnosis system (DTDS) which measured the percentage of TCT on the tongue surface. Fifteen oriental medical doctors evaluated TCT in 30 photographs. Afterward, the 15 assessors were trained for diagnostic criteria of TCT and evaluated the photographs again. The intraclass correlation coefficient (ICC) was used to obtain the agreement rate among the 15 assessors and the agreement rate between assessors' TCT scores and DTDS values. Results : The agreement rate among the 15 assessors after training was higher than before training. The agreement rate between assessors' TCT scores and DTDS values after training was also higher than before training. Furthermore, the difference of the agreement rate between before and after training was significant (p<0.05). Conclusions : The standardization of diagnostic criteria of TCT increased the agreement rate among the assessors and the agreement rate between assessors' TCT scores and DTDS values. Therefore, the standardization of diagnostic criteria is expected to contribute to the objectification and quantification of the tongue diagnosis system.

Synthesis and Static Charactetistics of Pentacene Derivatives for Organiv Thin-Film Transistor

손지희,강인남,오세용,박종욱 한국고분자학회 2007 한국고분자학회 학술대회 연구논문 초록집 Vol.2007 No.4

다양화, 특성화, 자율화로 포장된 입시제도와 7차 선택형 수능에 대한 고찰

손지희 교육비평 2003 교육비평 Vol.14 No.-

수준별 교육과정의 본질을 일깨워준 3명의 학자

손지희 교육비평 2005 교육비평 Vol.18 No.-

토마토쥬스와 KH$_2$PO$_4$가 Botrytis Cinerea LVF12 분생포자의 토마토 감염에 미치는 영향

손지희,이재필,김철승,임은경,송주희,김현주,박현철,문병주 한국식물병리학회 2001 식물병연구 Vol.7 No.3

잿빛곰팡이병균 Botrytis cinerea LVF12 분생포자의 토마토 잎 감염에 미치는 영양원의 영향을 조사하고 병원성을 검정한 결과, 0.1M KH$_2$PO$_4$를 첨가한 20% 토마토 쥬스로 만든 분생포자 부유액이 토마토 잎에서 일정하면서도 높은 발병도를 보여 감염에 효과적인 분생포자 영양원으로 선발하였다. 또한 토마토의 생육 단계별로 병원성을 검정한 결과, 유묘보다 성숙한 식물일수록 발병도가 높았고 하위엽이 상위엽보다 발병도가 높았다. 병징은 감염 초기에 갈색의 소형 점무늬가 잎에 형성되고 병반이 잎자루와 줄기까지 진전되면서 잎이 탈락하거나 줄기 전체가 갈변하여 고사하였다. 감염된 열매는 초기에 암갈색의 원형 병반이 형성되고 점점 진전되면서 열매가 물러 썩었는데, 습도가 높을 때에는 병든 잎, 줄기 및 열매가 잿빛의 균사와 분생포자로 뒤덮혀 자연 발생된 병징과 동일한 특성을 보여 주었다. Effects of tomato-juice and KH$_2$PO$_4$ as exogenous nutrients on the infection of Botrytis cinerea LVF12 and pathogenicity to tomato were investigated. B. cinerea LVF12, which was previously reported as a casual agent of the gray mold rot of perilla, was used for pathogenesis on tomato leaves. No infection was induced, and no lesion developed on tomato leaves by the conidial suspension of LVF12 when the inoculum was prepared in sterilized water. However, when the conidial suspensions of LVF12 added with various concentrations and conditions of tomato-juice were inoculated on whole tomato plants, the disease was induced readily, Among them, 20% tomato juice with 0.1M KH$_2$PO$_4$ appeared to be the most suitable nutrient to promote high disease incidence on tomato. For the pathogenicity test according to the growing stage of tomato, the mature leaves were more susceptible than seedlings. Symptoms on the infected plants were initial small gray spots at the inoculated area. Later the whole leaves, petioles and stems became gray and eventually fell off, Under high humidity conditions, the diseased leaves and stems were covered with gray hyphae and conidia. All symptoms of infected plants were identical to those in the field conditions.

Preparation of acryl syrup via continuous photo-polymerization

손지희,이재관 한국고분자학회 2011 한국고분자학회 학술대회 연구논문 초록집 Vol.2011 No.2