저생식샘자극호르몬 생식샘저하증과 부분 성장호르몬 부분결핍에 동반된 심한 자궁 저형성 1례

민세라,추영광,조현석,이현수,김자경,이향아,안성연 대한소아내분비학회 2012 Annals of Pediatirc Endocrinology & Metabolism Vol.17 No.2

Congenital hypogonadotropic hypogonadism is one of the causes of pubertal failure and primary amenorrhea, it is related to uterine hypotrophy. If the uterus is extremely hypotrophied, it is difficult to identify in imaging studies and can be misdiagnosed as a structural anomaly of internal genitalia. We report a case of extreme uterine hypotrophy in 18-year-old girl with primary amenorrhea that was finally diagnosed as hypogonadotrophic hypogonadism. The patient was initially suspected of Müllerian agenesis owing to the invisible uterus. After 4 months of treatment with estrogen, she showed significant growth of the uterus. 사춘기 지연이 있는 여자 환자에서 영상검사에서 자궁이 관찰되지 않을 때, 자궁의 발육부전인지 뮐러관 무발생인지를감별하는 것은 쉽지 않다. 이러한 경우에는 진단을 하기 전 호르몬 검사, 염색체 검사 등의 결과를 함께 평가하여야 하며, 에스트로겐 투여 후 자궁의 변화를 관찰해보는 것도 방법중의 방법 중의 하나이다. 저자들은 초기에 뮐러관 무발생을 의심하였다가 최종적으로 저생식샘자극호르몬 생식샘저하증으로 진단하고 에스트로겐 투여 후 자기공명영상을 통하여 자궁의 발육을 확인하였던 심한 자궁 저형성 증례를 경험하였기에 보고하는 바이다.

The Effect of Mirror Therapy to Improve Upper Extremity Function in Stroke Patients: A Meta-analysis

민세라,김태훈 한국인터넷방송통신학회 2024 International Journal of Internet, Broadcasting an Vol.16 No.1

This meta-analysis systematically reviewed studies on mirror therapy focused on arm and hand function in stroke patients, aiming to comprehensively assess the efficacy of mirror therapy interventions and furnish empirical support for its potential application and future development in the context of stroke rehabilitation. A rigorous search for articles published in international journals up to the year 2022 was conducted. Various assessment tools were employed to calculate effect sizes, evaluating the impact of mirror therapy on arm and hand function in stroke patients. Utilizing a random-effects model, mean effect sizes were determined, yielding a total effect size of 0.545. The effect sizes for the Brunnstrom Recovery Stage (BRS), Box and Block Test (BBT), Modified Barthel Index (MBI), Fugl-Meyer Assessment (FMA), and grip strength test were 0.957, 0.596, 0.490, 0.488, and 0.417, respectively. In summary, we suggest that mirror therapy engenders positive changes in functional recovery among stroke patients, establishing a foundation for its tailored clinical application based on individual subject characteristics.

펄스 레이다를 이용한 플래스틱 지뢰 탐지에 관한 사전 연구

민세일(Se-il Min),김세윤(Se-Yun Kim),이상설(Sang-Seol Lee) 대한전자공학회 1997 대한전자공학회 학술대회 Vol.1997 No.6

미얀마 민주화 과정

민세리 이화여자대학교 대학원 1997 硏究論叢 Vol.32 No.-

[독일] 독일의 작업용 보조공학기기 지원제도

민세리 한국장애인고용공단 고용개발원 2023 연구자료 Vol.2023 No.-

직관적 및 체계적 자유연상기법이 개념설계과정에서 고등학생 집단의 창의성 향상에 미치는 효과

민세기,최유현 대한공업교육학회 2009 대한공업교육학회지 Vol.34 No.1

The purpose of this study was to find the effect of intuitive free association and systematic free association on the creativity of high school students group in the conceptual design process. Based on this study result, the conclusion can be summarized as follows. 1. There was meaningful relation between intuitive free association and creativity factor of high school students. Mean value of experimental group A 's creativity and it's factor originality, practicality, elaboration, and fluency which treated intuitive free association was increased. 2. There was meaningful relation between systematic free association and creativity factor of high school students. Mean value of experimental group B 's creativity and it's sub factors: originality, problem solving, elaboration, and fluency which was treated systematic free association was increased. 3. It was found that two different divergent thinking does not show any meaningful difference in creativities of two groups. However, the meaningful difference was found in post creativity test in each groups sub-factors. There was meaningful difference in practicality factor, though there was no meaningful difference in originality, elaboration, fluency factors. Using the obtained results, it was concluded that intuitive thinking and systematic thinking play different roles in practicality which is one of sub-factors of the creativity of high school students. Consequently, it can be concluded that systematic thinking which leads students to take a step to solve a given problem can elicit more scientific thinking, and helps students create more practical solution in problem solving than intuitive thinking that emphasize the quantitative aspect of ideas. 본 연구는 직관적 자유연상기법과 체계적 자유연상기법이 개념설계과정에서 고등학생 집단의 창의성에 미치는 효과를 검증하기 위한 것으로서, 첫 번째는 직관적 자유연상기법이 개념설계과정에서 고등학생 집단의 창의성에 미치는 효과를 구명하는 것이고 두 번째는 체계적 자유연상기법이 개념설계과정에서 고등학생 집단의 창의성에 미치는 효과를 구명하는 것이며 세 번째는 직관적 자유연상기법과 체계적 자유연상기법이 개념설계과정에서 고등학생 집단의 창의성에 미치는 효과의 차이를 비교하여 창의성 증진에 각 기법이 미치는 효과의 차이를 통계적으로 비교 구명하는 것이다. 실험설계는 이질통제집단 사전사후검사 설계로서 인천광역시의 ◯◯고등학교 1학년 6개 학급 172명을 대상으로 실험집단A, 실험집단B를 구성하였다. 이 연구에 사용된 ‘개념설계 문제’와 ‘창의성 표현 검사지 A’, ‘창의성 표현 검사지 B’, 그리고 ‘창의성 평가 척도’는 다양한 문헌과 전문가의 타당성을 거쳐 연구자가 개발한 것으로 평가자간 상관계수를 통하여 신뢰성을 확보하였다. 이 연구의 결과를 요약하면 다음과 같다. 첫째, 직관적 자유연상기법이 고등학생 집단의 ‘창의성’과 하위요인인 ‘독창성’, ‘유용성’, ‘정교성’, ‘유창성’을 증진시키는 매우 효과적인 기법임을 확인 할 수 있었다. 둘째, 체계적 자유연상기법이 고등학생 집단의 ‘창의성’과 하위요인인 ‘독창성’, ‘유용성’, ‘정교성’, ‘유창성’을 증진시키는 매우 효과적인 기법임을 확인 할 수 있었다. 셋째, 고등학생 집단의 개념설계에 있어서 창의성의 하위요인인 ‘유용성’의 증진에 있어서는 체계적 자유연상기법이 직관적 자유연상기법보다 더 효과적인 기법임이 증명되었다.

펄스 레이다를 이용한 플라스틱 지뢰 탐지에 관한 사전 연구 ( Perlimiary Study on the Detection of Plastic Mines by Using Pulse Radar )

민세일,이상설,김세윤 대한전자공학회 1997 대한전자공학회 학술대회 Vol.1997 No.7

초발 정신병 환자에서 기저핵 구조물 부피의 패턴분석

민세리,이태영,곽유빈,권준수,Min, Sally,Lee, Tae Young,Kwak, Yoobin,Kwon, Jun Soo 대한생물정신의학회 2018 생물정신의학 Vol.25 No.2

Objectives Dopamine dysregulation has been regarded as one of the core pathologies in patients with schizophrenia. Since dopamine synthesis capacity has found to be inconsistent in patients with schizophrenia, current classification of patients based on clinical symptoms cannot reflect the neurochemical heterogeneity of the disease. Here we performed new subtyping of patients with first-episode psychosis (FEP) through biotype-based cluster analysis. We specifically suggested basal ganglia structural changes as a biotype, which deeply involves in the dopaminergic circuit. Methods Forty FEP and 40 demographically matched healthy participants underwent 3T T1 MRI. Whole brain parcellation was conducted, and volumes of total 6 regions of basal ganglia have been extracted as features for cluster analysis. We used K-means clustering, and external validation was conducted with Positive and Negative Syndrome Scale (PANSS). Results K-means clustering divided 40 FEP subjects into 2 clusters. Cluster 1 (n = 25) showed substantial volume decrease in 4 regions of basal ganglia compared to Cluster 2 (n = 15). Cluster 1 showed higher positive scales of PANSS compared with Cluster 2 (F = 2.333, p = 0.025). Compared to healthy controls, Cluster 1 showed smaller volumes in 4 regions, whereas Cluster 2 showed larger volumes in 3 regions. Conclusions Two subgroups have been found by cluster analysis, which showed a distinct difference in volume patterns of basal ganglia structures and positive symptom severity. The result possibly reflects the neurobiological heterogeneity of schizophrenia. Thus, the current study supports the importance of paradigm shift toward biotype-based diagnosis, instead of phenotype, for future precision psychiatry.

Low Cost and Portable Parahydrogen Generator for the PHIP

권순모,민세인,채희림,남궁성건,정근홍 한국자기공명학회 2017 Journal of the Korean Magnetic Resonance Society Vol.21 No.4

In the developed NMR hyperpolarization techniques, Parahydrogen-Induced Polarization (PHIP) technique is widely utilized to overcome the low sensitivity of the NMR/MRI. Parahydrogen generator is essential to produce high spin order of parahydrogen molecule. Commercial parahydrogen generator is well developed with user-friendly systems. However, it has drawbacks of long preparation time (~ 2h including cooling down time of 1h) and high cost (~ 200 million won) for the commercial setup. We designed a simple and portable parahydrogen generating system with low cost (~ 2 million won), which produce polarization in less than 1 min. With the designed parahydrogen generator, we successfully performed the PHIP with Wilkinson’s catalyst on styrene. This study will broaden the parahydrogen based polarization transfer study on many researchers by providing the simple portable and low cost parahydrogen generator.

Comparison of Effectiveness of Nasal Continuous Positive Airway Pressure and Nasal Intermittent Positive Pressure Ventilation for the Initial Treatment of Preterm Respiratory Distress Syndrome: A Prospective Pilot Study

이현수,민세라 대한신생아학회 2014 Neonatal medicine Vol.21 No.3

Purpose: To compare respiratory and clinical outcomes between the currently used strategy of Intubation, Surfactant, Extubation (InSurE) and nasal continuous positive airway pressure (NCPAP) and the alternative strategy of InSurE and nasal intermittent positive pressure ventilation (NIPPV) for the initial treatment of respiratory distress syndrome (RDS) in preterm newborns ≤32 weeks. Methods: Twenty-six comparable preterm infants with RDS were included in the study; 13 were randomized to NCPAP and 13 to NIPPV. In both groups, the InSurE procedure consisted of intubation, surfactant instillation and 2 h positive pressure ventilation followed by extubation, after which spontaneously breathing newborns were placed on NCPAP or NIPPV. Results: There were no differences in demographic characteristics or cardiorespiratory status among preterm infants enrolled in the study. The reinutation rate was lower among the infants treated with NIPPV than among those on NCPAP (8% vs. 46%, P<0.05) and the rate of aminophylline use between 4 and 7 days of age of was lower in the NIPPV group compared to the NCPAP group (8% vs. 30%, P<0.05). In addition, “InSurE with NIPPV” significantly reduced the overall duration of endotracheal ventilation and shortened the time to first feed compared to “InSurE with NCPAP”. Conclusion: “InSurE with NIPPV” displayed therapeutic benefits as the initial treatment of preterm RDS when compared with the currently used ventilator strategy, “InSurE with NCPAP” by preventing re-intubation and shortening the duration of endotracheal ventilation.