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우리나라의 주세체계와 건강증진사업의 연계방안에 대한 연구
천성수 ( Sung Soo Chun ),노성원 ( Sung Won Roh ),이계성 ( Kye Seong Lee ),( Rubelyn E. Inot ) 대한보건협회 2010 대한보건연구 Vol.36 No.2
This study was conducted to analyse the current Liquor tax rate system and to develop the alternatives of tax system and suggest the best practices between the system and national health promotion activities. We reviewed the articles and sources from journals and official dacuments of Korean Government. The current Liquor tax rate system can`t control alcohol consumption, therefore It is necessary to change it to a system that is closer to that of other developed countries. First, it is necessary to change the current Liquor Tax Levy in Korea, which consists of a high tax rate for high priced alcohol and a low tax rate for low priced alcohol. Current Liquor tax was implemented without proper consideration of the percentage of alcoholic content in diferent beverages, and this is a loophole that leaks tax revenue and further contributes to consumption of the high percentage alcohol that increases alcohol harms. Second, alcohol has produced problems for Korean national health and its people, so a “Health Earmarked Tax” is appropriate to be levied for health promotion and harm prevention activities. And Levy Tax is one of alternatives for national health promotion. Third, it is an essential effort to increase the price of the alcoholic beverages for reducing alcohol consumption. It is necessary to do activities on the national health promotion fields such as lifestyle changing projects, alcohol research projects, treatment and rehabilitations projects for community, and so on by the health promotion funds from alcoholic beverages.
정신분열병의 감정표현 불능증과 관련된 임상 및 증상 요인
이경하,김대호,노성원,남정현,Lee, Kyung-Ha,Kim, Dae-Ho,Roh, Sung-Won,Nam, Jeong-Hyun 한국정신신체의학회 2005 정신신체의학 Vol.13 No.1
연구목적 : 이 연구는 정신분열병 입원환자를 대상으로 감정표현 불능증과 임상변인 및 정신분열병의 연관 관계를 조사하고자 시행되었다. 방법: 두 대학병원 정신과 입원 시설에서 1년간 연속적인 수집을 통해 58명의 성인 정신분열병 환자가 이 연구에 참여하였다. 환자들에게 감정표현 불능증 척도(Toronto Alexithymia Scale, TAS), 양성 및 음성 증상척도(Positive and Negative Symptom Scale, PANSS), 간이정신진단검사(Symptom Checklist-90-Revised, SCL-90-R)를 시행하였다. 결과: 그 결과 TAS 총점은 SCL-90-R의 모든 하위 척도와 정적 상관 관계를 보였으며, 기존의 연구 결과와는 달리 PANSS의 양성증상, 음성증상, 일반 정신병리 척도 점수와는 유의한 상관이 없었다. 또한 '주관적 감각과 감정 경험의 혼동' 요인과 '감정 표현의 곤란' 요인은 SCL의 증상 척도와 유의하게 정적 상관하였으나, '공상의 빈곤'은 일부 하위척도와 부정 상관, '외부 지향적 사고'는 상관관계가 없었다. 다중회귀분석 결과는 SCL-90-R의 전체심도지수(GSI)가 감정표현 불능증의 28.2%를 설명하는 것으로 나타났다. 결론: 이 결과 및 객관적, 주관적 검사의 소견의 차이는 정신분열병의 감정표현 불능증이 두 가지 구성체, 즉 '감정 표현과 소통의 장애(상태적 요인)'과 '외부 지향적 사고(특성적 요인)'로 구성됨을 시사한다. 향후 정신분열병 환자를 대상으로 한 TAS의 구성 타당도 연구가 필요하다. Objectives : This study looked at the symptoms of alexithymia in schizophrenia and their association with clinical variables and schizophrenic symptomatology. Methods Consecutive fifty eight inpatients with DSM-IV diagnoses of schizophrenia completed 26item version of Toronto Alexithymia Scale (TAS), Symptom Checklist-90-Revised(SCL-90-R), and Positive and Negative Syndrome Scale(PANSS). Results : Authors did not find any correlation between scores of PANSS and TAS. However, all the subscale scores of SCL-90-R were significantly correlated with total score of TAS. Also, 'difficulty identifying and deistinguishing between feelings and bodily sensations' and 'difficulty describing feelings' significantly correlated with SCL-90-R subscale scores. 'Reduced daydreaming' had mixed findings and 'externally oriented thinking' did not correlate. Multiple regression model included Global Severity Index of SCL-90-R accounting 28.2% of variance for TAS scores. Conclusion : These findings together with discrepancy in results between objective and subjective tests suggest that alexithymia in schizophrenia may have two constructs, 'difficulty to describe and communicate feelings(state)' and 'externally oriented thinking(trait)' Authors suggest further study needs to confirm construct validity of TAS in this population.
흰쥐 C6 신경교종 세포에서 Venlafaxine 그리고 Dexamethasone 처리가 열충격 단백질 70의 발현에 미치는 영향
유재학,이준석,양병환,최미란,채영규,김석현,노성원,오동열,최인근,Yu, Jae-Hak,Lee, Jun-Seok,Yang, Byung-Hwan,Choi, Mi-Ran,Chai, Young-Gyu,Kim, Seok-Hyeon,Roh, Sung-Won,Oh, Dong-Yul,Choi, Ihn-Geun 대한생물정신의학회 2005 생물정신의학 Vol.12 No.2
Object:The intracellular action of the antidepressant, venlafaxine, was studied in C6-gliomas using heat shock protein 70(HSP70) immunocytochemistry and HSP70 Western blots because HSP70 is associated with stress and depression. Methods:To examine how the glucocorticoid affects the expression of HSP70 in nerve cells, the rat C6 glioma cell was treated with dexamethasone for 6 hours. In addition, venlafaxine was administered to the experimental groups of C6 glioma cells for 1, 6, 24, and 72 hours each, after which the expression of HSP70 was investigated. Finally, venlafaxine and dexamethasone were simultaneously administered to the experimental groups for 1, 6, 24, and 72 hours, followed by an investigation of the expression of HSP70. Results:The short term(1 hour) venlafaxine treatment significantly increased the level of HSP70 expression. The short term treatment of venlafaxine with dexamethasone also increased the level of HSP70 expression but this reduction was not statistically significant. The long term(72 hours) venlafaxine with dexamethasone treatment significantly reduced the level of HSP70 expression. The long term treatment of venlafaxine also reduced the level of HSP70 expression but this reduction was not statistically significant. Dexamethasone(10uM, 6hours) did not affect the level of HSP70 expression compared with controls. Conclusion:Venlafaxine increases the expression of HSP70 at short term treatment, but prolonged treatment with dexamethasone suppresses the expression of HSP70.
김대호,이해원,노성원,최준호,박용천,정승아,남정현 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6
Objectives : The direct causal relationship between the experience of sexual assault and development of psychiatric disorder remains uncertain. However, studies consistently show that those with history of this horrendous event report a wide range of symptoms, higher level of distress, and various social and psychological problems. This study investigated the prevalence and associated risk factors in a cohort sample of 340 Korean psychiatric patients. Methods : Data from consecutive 340 new patients were gathered at a psychiatric department of a university affiliated hospital. Participants completed Life Events Scale, Symptom Checklist-90-R, State-Trait Anxiety Inventory, Beck Depression Inventory, and Dissociative Experiences Scale. Results : History of sexual assault was reported by 11.5% of respondents (women 18.6% ; men 2.1%). Bivariate analysis revealed that women (p<.001), divorced or widowed and never been married (p<.05), unemployed and students or housewives (p<.05), monthly income more than 2 million Won (p<.05) were associated significantly with experience of sexual assault. All the scores from the scales but Beck Depression Inventory were significantly higher for the sexually assaulted. Multiple logistic regression analysis revealed that women were 12 times more likely to be sexually assaulted (Odds ratio=12.24, 95% CI=3.51 -42.64). Other risk factors included younger age and interacdon of post-traumatic stress disorder (PTSD) and Global Severity Index. Conclusion : This study supported the risk factors of sexual assaults identified in western literature. Clinicians can be alert for any history of sexual assault when younger women with PTSD present higher level of symptomatology.