리튬 유황전지용 폴리우레탄 고분자 전해질의 전기화학적 특성

김형주,신준호,김종화,김기원,안효준,안주현,Kim, Hyeong-Ju,Shin, Joon-Ho,Kim, Jong-Hwa,Kim, Ki-Won,Ann, Hyo-Jun,Ahn, Ju-Hyun 한국전기화학회 2002 한국전기화학회지 Vol.5 No.2

본 연구에서는 높은 인장강도와 탄성력을 가지는 다공성 폴리우레탄(polyurethane, PU)을 지지체(matrix)로 이용하고, 유기 전해액 ethylene carbonate(EC), propylene carbonate(PC), tetraethylene glycol dimethylether(TG)와 1M $LiCF_3SO_3$를 부피비 1:1 비율로 혼합하여 액체 전해액을 제조하였으며, 높은 이론용량을 가지는 Li/S전지에 적용하여 전기 화학적 특성을 조사하였다. 1M $LiCF_3SO_3$에 TG를 첨가할 경우 유기 전해액의 함침량이 약 $750\%$ 증가하였으며 방전용량$(1065mAh/g{\cdot}sulfur)$ 및 사이클 특성이 가장 우수하였다. 1M $LiCF_3SO_3$에 TG/EC(v/v,1:1) 및 PC/EC(v/v,1:1)를 첨가한 경우 이온 전도도는 각각 $3.15\times10^{-3}(S/cm)$ 와 $3.18\times10^{-3}(S/cm)$로 나타났다. Polyurethane was used as matrix for polymer electrolytes with liquid electrolyte consist of organic solvent as ethylene carbonate(EC), propylene carbonate(PC), and tetraethylene glycol dimethylether(TG) and 1M $LiCF_3SO_3$, which has high mechanical strength and porosity. Electrochemical properties fur polyurethane electrolytes with various liquid electrolytes were evaluated. The amount of immersed liquid electrolyte for TG with 1M $LiCF_3SO_3$ was increased to about $750\%$ by weight, and initial discharge capacity and cycle performance was better than others. Ionic conductivity for TG/EC(v/v,1:1) and PC/EC(v/v, 1:1) with 1M $LiCF_3SO_3$ was about $3.15\times10^{-3} S/cm, \;3.18\times10^{-3}S/cm$

특성도를 이용한 결측치 대체방법

김형주,김동재,Kim, Hyungju,Kim, Dongjae 한국통계학회 2017 응용통계연구 Vol.30 No.3

임상시험에서 어떻게 결측치를 다룰 것인가 하는 것은 큰 문제이다. 주로 주분석에서 사용하는 ITT원칙은 결측치가 어떠한 메커니즘을 따른다는 가정 하에 결측치를 대체 하지만 가정에 대한 타당성이 불확실한 문제가 있다. 즉, 올바른 결측치 대체방법은 매우 중요하다. 본 연구에서는 Kang과 Kim (1997)이 제안한 일치도와 유지도의 개념을 이용하여 새로운 결측치 대체방법을 제안하였다. 또한 실제자료를 이용하여 예제를 제시하고 Monte Carlo 모의실험을 통하여 기존방법과 대체 성능을 비교하였다. How to handle missing data is a main issue in clinical trials. We impute missing data based on missing data that follows a mechanism according to the intention-to-treat rule. However, using the right imputation method for missing data is very important because this supposition is unclear. We suggest a new imputation method for missing data using agreement and maintenance introduced by Kang and Kim (1997). We give an example and adapt a Monte Carlo simulation to compare the performance between the established method and the suggested method.

미생물을 이용한 대마의 리그닌과 펙틴 분해

김형주,권길광,서규원,김민철,김형섭,고준석,Kim, Hyung-Joo,Kwon, Kil-Koang,Seo, Kyu-Won,Kim, Min-Chul,Kim, Hyung-Sup,Koh, Joon-Seok 한국섬유공학회 2009 한국섬유공학회지 Vol.46 No.6

In this study, microbial degradation of lignin and pectin in raw hemp was investigated. Using lignin and pectin containing media, various microorganisms were isolated from soil and fecal samples of ruminant. The isolates were identified using the 16s rRNA method. The isolated strains were Klebsiella sp., E. coli, Aspergillus fumigatus, and Burkholderia sp. For the degradation of hemp, a pre-cultured isolate was inoculated (5% v/v) into the medium containing raw hemp (as a sole carbon source: 1% w/v) and nitrogen sources and the mixture was incubate aerobically for 168 hours in a shaking incubator (200 rev $min^{-1}$) at $30^{\circ}C$. The hemp biodegradation activity of the identified microorganism was measured by FT-IR. The FT-IR results showed that the Klebsiella sp. has the highest lignin and pectin degradation activity. These results show that the isolates and the reaction conditions could be applied to the conventional hemp fiber refinery processes.

Siewert 분류에 의한 협의의 분문부 위암(type II)과 분문하 위암(type III)의 검토

김형주,권성준,Kim Hyoung-Ju,Kwon Sung Joon 대한위암학회 2004 대한위암학회지 Vol.4 No.3

Purpose: To determine the clinical value of the Siewert classification for gastic-cancer patients in Korea, we evaluated and compared the clinicopathologic factors of type II and type III cancer. Materials and Methods: The medical records of 89 consecutive patients who had undergone surgery for an adenocarcinoma of the gastroesophageal junction (GEJ) at the Department of Surgery, Hanyang University Hospital, between Jun. 1992 and Dec. 2003 were reviewed retrospectively. Results: There were one patient with type I, 12 pateints with type II and 77 patients with type III. During the same period, 1,341 patients underwent surgery for a gastric carcinoma, so proportion of GEJ cancer being $6.6\%$. The median followup duration was 31 months (range: $2\∼135$ months), and the follow-up rate was $100\%$. Between type II and type III cancers, there were no significant differences in the clinicopathologic variables including age, sex, gross appearance, histologic type, depth of invasion, and pathologic stage. The longest diameter of the tumor was larger in type III ($6.1\pm2.1$ cm) than in type II ($3.9\pm1.1$ cm)(P=0.001). A total gastrectomy with Roux-en-Y esophagojejunostomy was done most frequently, while jejunal interposition was done in 3 cases of type II and 2 cases of type III. More than a D2 lymphadenectomy was done all cases. The numbers of dissected lymph nodes and metastatic lymph nodes in type II were 43.8 and 5.8 respectively, while they were 49.8 and 8.1 in type III, but the difference between the two groups were not statistically significant. The mean length of the proximal resection margin was $15\pm5$ mm in type II and $21\pm13$ mm in type III, but this difference was not statistically significanct. The time to recurrence after operation was 19.3 months in type II and 16.9 months in type III. The five-year survival rates of type II and III were $68.8\%\;and\;52.7\%$ respectively, but difference was not significant. Conclusion: There were no significant differences in the clinicopathologic variables, including survival rate, between type II and type III cancers in Korean patients According to these findings, it appears to be reasonable to classify type III cancer as a cardia cancer in a broad sense.

위에 발생한 소세포암의 임상 경험

김형주,박문향,권성준,Kim, Hyoung-Ju,Park, Moon-Hyang,Kwon, Sung-Joon 대한위암학회 2005 대한위암학회지 Vol.5 No.4

위에 발생하는 원발성 소세포암은 매우 드물며 예후는 좋지 않아 초기에 발견되어도 60% 이상이 1년 이내에 사망한다. 본원 외과에서 수술치료를 받은 위소세포암 첫 번째 증례는 수술소견상 복막전이 소견 등으로 근치적 수술이 불가능하여 위공장문합술을 시행하였다. 수술 후 etoposide, cisplatin화학요법을 시행하고 6개월 뒤에 찍은 CT촬영상 복막전이, 림프절전이가 악화되어 paclitaxel, cisplatin으로 약제변경 하였으나 수술 후 14개월째 사망하였다. 두 번째 증례는 내시경 조직검사상 위선암과 소세포암의 복합 소견을 보였으며 CT 촬영상 복강동맥주위 림프절종대 및 간전이 소견이 발견되었다. TS-1과 cisplatin 선행화학요법 2차 시행 후 림프절 종대는 완전관해, 원발소 및 간전이소는 부분관해 소견을 보여 위전절제술 및 확대림프절 절제술을 시행하였다. 수술로 절제된 위 및 주변 림프절 35개의 조직검사상 암세포가 모두 사멸되었으며 위내 원 발병소는 심한 심유화변성 소견을 보여 수술 전 사용한 항암요법이 유의했다고 판단되었다. 이에 수술 후에도 동일 제제로 4차례 추가 투약을 하였다. 수술 후 6개월에 시행한 CT촬영상 간전이가 진행된 소견을 보여 간우엽 후부절제술을 시행하고 이후 ininotecan과 cisplatin을 이용한 항암화학요법을 5차례 시행하고 있으며 술 후 14개월째 생존 중이다. 세 번째 증례는 순수 소세포암으로 근치적 위아전절제술을 시행하였으며 수술 후 5차례에 걸쳐 TS-1, cisplatin 보조항암화학요법 시행하였고 수술 후 13개월째 재발 없이 생존 중이다. To clarify the clinicopathologic features of small-cell carcinomas (SCC) of the stomach, we reviewed three cases of surgically treated SCC. The first case was a pure SCC, with severe pancreatic invasion and peritoneal seeding. A gastro-jejunostomy was performed. Postoperative chemotherapy was performed with CDDP and VP-16 (8 cycles) but showed disease progression (PD); a consecutive chemotherapy with CDDP and irinotencan (2 cycles) also showed PD. A third line with CDDP, VP16, ifosfamide, and mesna was followed by a 4th line (CDDP and Taxol). The male patient died with liver metastasis and peritoneal seeding 14 months after the operation. The second case was a SCC mixed with a poorly differentiated adenocarcinoma. Profound lymphadenopathy and liver metastasis were found. Two cycles of preoperative chemotherapy with TS-1 and CDDP were performed, which showed nearly complete remission for lymphadenopathy and partial response for the primary tumor site and liver metastatic lesion. A total gastrectomy and extended lymphadenectomy was performed. There were no viable cancer cells in 35 retrieved lymph nodes. Postoperative chemotherapy using the same regimen was performed for 4 cycles. Enlarged liver metastasis was found at the follow-up CT scan, so a posterior segmentectomy of liver was performed. After liver surgery, the chemotherapy regimen was changed to irinotecan and cisplatin. This male patient has been in good health for the f4 months since gastric surgery. The third case was a pure SCC, and a subtotal gastrectomy was performed curatively. That male patient received 5 cycles of TS-1 and is still in good health 14 months after operation.

갑상선 결절의 수술적 치료에 있어서 세침흡인세포검사의 진단적 유용도

김형주,정파종,Hyoung-Ju Kim,M,D,and Pa Jong Jung,M,D 대한갑상선-내분비외과학회 2001 The Koreran journal of Endocrine Surgery Vol.1 No.1

Purpose: Fine-needle aspiration cytology (FNA) and Frozen section biopsy (FS) have been used to distinguish benign lesions from malignancies and for deciding the extent of operative procedures to be used in the management of thyroid nodules. We performed this study in order to determine the diagnostic value of FNA, the need for FS in intraoperative procedures, and their value in deciding the extent of surgery. Methods: The medical records of 365 consecutive patients who had undergone surgery for thyroid nodules at the Department of Surgery, Hanyang University Hospital, between Jan. 1996 and Dec. 1998 were reviewed retrospectively. Both FNA and FS were performed on all patients who underwent thyroid surgery during this period. Among these, 35 patients who were diagnosed as insufficient for diagnosis by FNA were excluded. Results: Definitive histopathological diagnosis revealed benign lesions in 232 patients and malignancies in 98. A borderline group consisted of patients whose specimens were interpreted as follicular neoplasms by FNA and FS. The overall results for FNA and FS were as follows: sensitivity, 98 versus 100; specificity 97 versus 99; and diagnostic accuracy, 97 versus 99%. Five patients who were diagnosed with benign lesions by FNA were rediagnosed by FS as having malignant lesions. The final diagnosis was papillary carcinoma. Of the 45 patients who were interpreted borderline by FNA, 7 patients had benign lesions and 38 were borderline by FS. Finally, 34 patients were diagnosed as having benign lesions and 11 as having malignancies. Conclusion: FNA has a high diagnostic accuracy for the differential diagnosis of thyroid nodules. FS may be unnecessary for patients whose FNA results indicate malignancy, particularly in cases of papillary carcinoma, therefore the routine use of FS for patients who have been diagnosed as having a papillary carcinoma by FNA may be omitted. If FNA results are borderline, FS may be helpful in confirming a follicular neoplasm. If FNA indicates a benign status, FS seems to be necessary to decide the extent of surgery. (Korean J Endocrine Surg 2001;1:73-77)

상류 후류의 익렬 유동에 미치는 영향에 대한 실험적 연구

김형주,조강래,주원구,Kim, Hyeong-Ju,Jo, Gang-Rae,Ju, Won-Gu 대한기계학회 2001 大韓機械學會論文集B Vol.25 No.3

This paper is concerned with the effect of cylinder wakes upstream on blade characteristics of compressor cascade(NCA 65 series). At first, it is found that the velocity defect ratio of cylinder wake varies according to the acceleration and deceleration in a flow field but, is conserved nearly constant at flow downstream the cascade, irrespective of the flow path in the cascade. When a cylinder wake flows along near the suction surface of the blade, or impinges on the leading edge, the turbulent velocities are supplied on or inside the outer edge of boundary layer near the leading edge of suction surface, and the transition to a transitional or turbulent boundary layers is induced, so that the laminar separation is prevented, but the profile loss increases. The transition of boundary layer to a transitional or turbulent one is strongly related with the strength of added turbulent velocities near the leading edge on the suction surface, which is influenced by the flow path of a cylinder wake.

사회적 기업가정신에 대한 사회적 자본의 매개효과가 사회적 성과에 미치는 영향

김형주,전인오,Kim, Hyung-Ju,Jeon, In-Oh 한국벤처창업학회 2017 벤처창업연구 Vol.12 No.5

The purpose of this study is to examine whether the social capital supported by social enterprises play a role in ensuring self-sustaining and sustainable growth, and to examine whether the mediating effect of social capital have a central effect on social performance. The results of this study are as follows: Innovation and orientation-to-social-value of social entrepreneurship have positive effects on structural capital, and positive influence on cognitive capital and relational capital, but innovation only has no effect. In addition, social entrepreneurship is partially mediated by structural capital. In the mediating effect between social entrepreneurship and cognitive capital, only the risk-taking and the orientation-to-social-value have a partial mediation effect on cognitive capital. However, only the initiative of relational capital was found to have a full mediating effect. And social capital has a positive effect on social performance as a whole. In conclusion, considering that the realization of economic purpose and other social purpose of social enterprises will help to develop and create jobs in the local community, and that they are engaged in business activities in a poor management environment, to provide policy support for inducing high value-added industries through industry-specific collaborations.

양성 라텍스를 이용한 도공층 구조의 최적화

김형주,황석우,박규재,이용규 ( Hyung Ju Kim,Seok Woo Hwang,Kyu Jae Park,Yong Kyu Lee ) 한국산림과학회 1997 한국임학회 학술발표논문집 Vol.1997 No.-

2차 Seed Grain을 사용한 ZnO 바리스터의 제조

김형주,마재평,백수현,Kim, Hyung-Joo,Mah, Jae-Pyung,Paek, Su-Hyon 대한전자공학회 1990 전자공학회논문지 Vol.27 No.3

1차와 2차 Seed grain을 제조하였다. 보다 큰 grain size를 갖는 1차 seed의 제조 조건은 2.0mol.%의 $BaCO_3$ 첨가와 10시간의 소경이었다. 가장 큰 2차 seed를 얻을 수 있는 1차 seed의 첨가량이 3wt.%로 나타나서, 전통적 방식으로 제조된 바 있는 저전압용 바리스터계에 이를 첨가하여 저전압 ZnO 바리스터를 제조하였다. 이와 같은 조건하에서 제조된 바리스터는 대개 10V/mm의 항복전압과 15~22의 비선형지수를 나타냈다. We fabricated primary and secondary seed grains. Primary seed grains having larger grain size were obtained under the conditions that were 2.0mol.% $BaCO_3$ and 10 hours sintering. The amount of primary seed grain that yield the largest secondary seed grain was chosen as 3wt.% and we fabricated the low voltage varistors which were jointed the low voltage-oriented ZnO varistor system made by conventional method with the secondary seed grains. As a result, the ZnO varistors under those conditions showed approximately 10V/mm of nonlinear resistance and 15-22 of nonlinear exponent.