19세기 京華世族의 實景山水畵後援배경과 畵壇에 미친 영향

金賢貞(Kim Hyunjung) 미술사연구회 2009 미술사연구 Vol.- No.23

Real-scenery landscape paintings (silgyeong sansuhwa, 實景山水畵) in the nineteenth century were produced in various forms such as albums, scrolls or folding screens, since patronage for the real-scenery landscape paintings by gyeonghwasejok had expanded due to travel for exploring natural beauties and their interest in collecting paintings and calligraphies. Gyeonghwasejok refers to aristocrats (yangban) living in the nation’s capital whose families’ social and economic status were guaranteed by monopolization of their government official posts. Gyeonghwasejok was a patron to painters, as well as a collector with the power of controlling the art market. Gyeonghwasejok, who dominated the painting circles in the nineteenth century, chose jabidaeryeong hwawon (painters-in-waiting) who were regarded as the best painters in their time after Kim Hong-do or local literati painters for their commissions. Gyeonghwasejok patronized real-scenery landscape paintings in the political situation of Noron (Old Doctrine)’s in-law government in the nineteenth century because of fascination over traveling for exploring the beauty of nature and their interest in collecting paintings and calligraphies, expression of consciousness of lineage and channels for political exchange, and the increased trend of treasuring Kim Hong-do’s Haesan-cheop. Gyeonghwasejok was active in producing real-scenery landscape paintings, as they were infatuated with traveling and collecting, while reading travel poems and travel diaries of their predecessors or treasuring inherited objects related to traveling for exploring the beauties. Further, Gyeonghwasejok reproduced gajeon hwacheop (painting albums preserved in one’s family) or gajeon hwabyeong (folding screens preserved in one’s family) that revealed their consciousness of lineage, or produced travel albums of paintings to get forewords or inscriptions from high-ranking officials, so they strived to secure their political positions. This is evidenced by Gosangugok sihwabyeong commissioned in 1803 by Andong Kim’s clan, a representative Noron’s family in power, and by the fact that they commissioned a painter to remake a copy of Gokwun gugok docheop in 1804. With the increased trend of treasuring Kim Hong-do’s Haesan-choep, gyeonghwasejok accompanied jabidaeryeong hwawon their journeys to produce travel albums of paintings or commissioned painters to reproduce travel albums of paintings in Kim Hong-do’s style. Real-scenery landscape paintings in the nineteenth century were patronized by two political powers; Noron’s gyeonghwasejok, who has substantial political power, and Soron(Young Doctrine)’s gyeonghwasejok, who cooperated with a family in power. Noron’s gyeonghwasejok who settled around the capital had the power not only in political circles but in art circles as well. Noron Yi Gwang-mun (1778-1838)’s Haesan docheop is a travel album of paintings executed by Kim Ha-jong (1793-1878) for his patron Yi Gwang-mun in his distinctive manner, which did not follow Kim Hong-do’s Haesan-choep, but rather reflected Yi’s idea of depicting actuality. This paper confirms that Kim ha-jong, who died in 1878, had a pen name of“Sungyanggeosa,”or was called “Yeonungongyang,”and it is presumed that Kim Jeong-hee (1786-1856), who had associated with Yi Gwang-mun, left an inscription on the cover of the album. Moreover, in the nineteenth century it was very competitive to be nominated by dodanghoegwon, so Jeong Won-yong, Yi Pung-ik, Yi Yu-won of Soron could not be appointed to high-ranking official posts without the support of Noron’s family in power. Haoedo sipgokbyeong patronized by Soron Jeong Won-yong (1783-1873) in 1828 was the gajeon hwabyeong commissioned to Yi Ui-seong, aimed to elevate the Jeong clan’s prestige, which is a reproduction of Haoesanghanakgang ildaedo, which included the poems of his ancestor Jeong Yu-gil and of the hometown of the Jeong clan. Jeong Wonyong published Dongseong gyoyeojip which compiled

동결 해동한 포배 이식에 있어서 동결시기가 임신결과에 미치는 영향

김현정,김충현,이중엽,권재희,황도영,김기철,Kim, Hyun-Jung,Kim, Chung-Hyon,Lee, Joong-Yeup,Kwon, Jae-Hee,Hwang, Do-Yeong,Kim, Ki-Chul 대한생식의학회 2010 Clinical and Experimental Reproductive Medicine Vol.37 No.1

목 적: 배양 환경과 동결 기술이 발달함에 따라 동결 포배의 해동-이식의 빈도가 증가하고 있으며, 신선 주기와 마찬가지로 해동-이식 주기에서도 질 좋은 배아를 선별하는 것은 임신 성공 여부를 결정하는 아주 중요한 과제이다. 본 연구는 동결 당시 포배로의 발달 속도가 임신 결과에 미치는 영향을 알아보기 위하여, 수정 후 5일 및 6일째 동결한 포배의 해동-이식 후 임신율을 비교 분석하였다. 연구방법: 2006년 1월부터 12월까지 5일째 또는 6일째 동결한 포배를 해동하여 2007년 6월까지 융해 이식한 87명, 93주기를 대상으로 하였다. 동결법은 ethylene glycol과 DMSO를 이용한 유리화 동결법을 이용하였으며, 팽창 포배는 인위적인 수축을 시행 후 동결하였다. 해동 과정은 이식 전날 시행하여 15~18시간 배양액에서 배양 후 재팽창 여부를 확인하였다. 결 과: 5일째 동결한 포배를 해동-이식한 52주기와 6일째 동결한 포배를 해동-이식한 41주기에서 환자의 나이, 이식한 배아의 수, 해동 배아의 생존율 등 임신 결과에 영향을 미칠만한 요인들의 차이는 없었다. 그러나 생화학적 임신율, 임상적 임신율, 진행 임신율, 착상율 등은 5일째 동결한 포배를 해동-이식한 주기에서 높게 나타났다. 결 론: 5일째 동결한 포배를 해동-이식했을 때의 임신율은 6일째 동결한 포배를 해동-이식했을 때의 임신율보다 2배 이상 높았으며, 이는 신선 주기와 마찬가지로 해동-이식 주기에서도 동결 전 배아의 발달 속도의 차이를 임신 성공 예측의 중요한 지표로 사용할 수 있음을 시사한다. Objectives: Likewise fresh cycle, it is also important to select right blastocysts for transfer in purpose of improving the pregnancy and implantation rates in frozen-thawed embryo transfer (ET) cycles. To investigate the relationship between the developmental velocity at the time of cryopreservation and pregnancy rates, we compared pregnancy rates between the day 5 cryopreservation group and the day 6 cryopreservation group. Methods: Transfers of frozen-thawed blastocysts which had been cryopreserved by vitrification on day 5 or day 6 were performed between January 2006 and June 2007. Ethylene glycol, DMSO, and pull and cut straws were used for vitrification and artificial shrinkage was done in expanded blastocysts. Thawing was performed on the day before transfer and thawed blastocysts were cultured in for 15~18 hrs in Quinn's blastocyct media. Blastocyst survival was assessed before transfer and post-thaw survival was defined as >50% of cells remaining intact and blastocoele re-expansion by the time of transfer. Results: Transfers of thawed blastocyst had been cryopreserved on day 5 were 52 cycles and 41 transfer cycles were cryopreserved on day 6. Patient characteristics, the number of transferred embryos and the survival rate of thawed blastocysts were not different in each cryopreservation day. But the biochemical pregnancy, clinical pregnancy, ongoing pregnancy, and implantation rate were significantly high in transfer of frozen-thawed blastocyst which were cryopreserved on day 5. Conclusions: The clinical pregnancy and implantation rate of day-5 blastocyst showed significantly higher than those of day-6 blastocyst in frozen-ET cycles. This result indicated that developmental rate of blastocyst at cryopreservation time in frozen-thawed cycle is discriminative marker of pregnancy outcome as like in fresh cycle.

지백지황탕(知栢地黃湯)으로 호전된 진행성 색소성 자반병의 한방치료 1례

김현정,김태연,이창원,김창환,Kim, Hyun-Jung,Kim, Tae-Yeon,Lee, Chang-Won,Kim, Chang-Hwan 대한한방안이비인후피부과학회 2013 한방안이비인후피부과학회지 Vol.26 No.2

Objective : The purpose of this report is to know the effect of Jibaekjihwang-tang(知栢地黃湯) on progressive pigmented purpuric dermatosis. Methods : We experienced one case of progressive pigmented purpuric dermatosis treated with Jibaekjihwang-tang(知栢地黃湯). We used visual analogue scale(VAS). Results : After the treatment the grade of VAS was decreased and purpuras, pruritus and dryness of skin were disappeared. Conslusion : Jibaekjihwang-tang(知栢地黃湯) can be used on the treatment of progressive pigmented purpuric dermatosis.

알코올을 처리한 HepG2 세포에서 참죽나무 잎 추출물의 세포 보호 및 항산화 효과

김현정,조수연,김정봉,김헌웅,최정숙,장환희,Kim, Hyun-Jeong,Cho, Su-Yeon,Kim, Jung-Bong,Kim, Heon-Woong,Choe, Jeong-Sook,Jang, Hwan-Hee 한국식품영양학회 2018 韓國食品營養學會誌 Vol.31 No.4

All the parts of the Cedrela sinensis A. Juss., including the seeds, roots, and leaves, have been known to exert medicinal effects. The C. sinensis and its major compound, quercetin, were previously reported to exhibit the anti-inflammatory and anti-oxidative activities. However, the hepatoprotective effects of the C. sinensis leaves against the alcohol-induced oxidative stress in the HepG2 cells have not been studied. In this study, we investigated the antioxidant activities and analyzed the flavonoid contents of the C. sinensis-leaf extract (CE). The total flavonoid contents of the CE is 1,874.5 mg/100 g dry weight (DW), while the total quercetin 3-O-rhamnoside (quercitrin) contents, which was identified as the major flavonol in the CE, is 1,456.0 mg/100 g DW. In the ethanol-stimulated HepG2 cells, the CE effectively prevented the cytotoxic effect and increased the gene expression of the antioxidant enzymes, such as the heme oxygenase-1 (HO-1) and the glutathion peroxide (GPx). The level of the reactive oxygen species (ROS) production was significantly decreased in the CE-treated HepG2 cells. In conclusion, the C. sinensis extract suppressed the alcohol-induced oxidative stress in the HepG2 cells via the induced GPx and HO-1 gene expressions. It is expected the CE positive effects will likely be attributed to the flavonoids, like the quercetin, within the CE.

미디어 퍼포먼스 「마담 프리덤」에 나타난 주인공 여성의 재현과 그 의미

김주희(연구원,조교수) ( Ju-hee Kim ),김현정(연구원,조교수) ( Hyun Jung Kim ) 대한무용학회 2016 대한무용학회논문집 Vol.74 No.3

This paper explores meanings of a main female character in Madame Freedom (2013), a media performance of Hyo-jin Kim and Hyung-su Kim. This research investigates characteristics of the heroine in its original novel and movie; and examines what the roles of dances and media workings are respectively and what the choreographer utilizes the original works in Madame Freedom. This paper argues that the media work shows a Korean housewife``s passion, sexuality & freedom; ambivalent interpretations; and strategic reconstruction of particularity and universality. These provide a way to produce diverse interpretations by exploring complex relations of novel, movie, and media performance.

우리나라 학생들의 과학 영역 성취 특성 탐색

김현정,Kim, Hyun Jung 대한화학회 2021 대한화학회지 Vol.65 No.1

This study aimed to analyze achievement characteristics of Korean students in the results of PISA 2018 science domain. To this end, the characteristics of PISA 2009 to PISA 2018 science were analyzed in terms of the percentage of each performance level and the ratio of male and female by achievement level; in addition, the percentage of correct answers by framework subscale was compared with PISA 2015. The results showed that Korea has a higher percentage of students at the lower level of achievement as compared to the high-ranking countries of PISA, and the ratio of students at the higher level of achievement was lower. On average, the difference in achievement between boys and girls was negligible; however, but at the higher achievement level, the ratio of boys continued to be higher than that of girls. In addition, in the PISA science framework, the percentage of correct answers of the questions corresponding to 'personal' of 'contexts', 'evaluate and design scientific enquiry' of 'competencies', 'epistemic' of 'knowledge', and 'high' of 'cognitive demand' increased; similarly, and achievement improved as compared to PISA 2015. Based on these results of the study, we propose a method for improving teaching and evaluation to foster Korean students' scientific competence. 본 연구의 목적은 PISA 2018에서 나타난 우리나라 학생들의 과학 영역 성취의 특징을 분석하는 것이다. 이를 위하여 PISA 2009 ~ PISA 2018 과학 영역에서 우리나라 학생들의 성취 수준별 비율과 성취 수준별 남녀 비율을 살펴보았으며, 평가틀 하위 요소별 정답률을 PISA 2015와 비교하여 살펴보았다. 연구 결과 우리나라는 PISA 주요 성취 상위국에 비하여 하위 성취 수준 학생들의 비율이 높았던 반면, 상위 성취 수준 학생들의 비율은 낮았다. 평균에서 남학생과 여학생의 성취 차이는 거의 없어졌으나, 상위 성취 수준에서 남학생의 비율은 여학생의 비율보다 높은 것이 유지되고 있었다. 또한, 평가틀에서 '맥락'의 '개인적', '역량'의 '과학 탐구의 설계 및 평가', '지식'의 '인식론적' 지식, '인지적 요구'의 '상'에 해당하는 문항의 정답률이 상승하여 PISA 2015에 비해 성취가 향상되었다. 연구 결과를 토대로, 우리나라 학생들의 과학 역량 함양을 위한 교수·학습과 평가의 개선 방안을 제안하였다.

Changes in Salivary Flow Rate and pH in Stressful Conditions

김현정,서봉직,Kim, Hyeon-Jung,Suh, Bong-Jik The Korean Academy of Orofacial Pain and Oral Medi 2001 Journal of Oral Medicine and Pain Vol.26 No.1

타액은 그 양과 조성 등에 있어 많은 인자들의 영향을 받는다. 타액분비 감소는 구강의 자정작용, 완충능, 치아우식저항성 등 타액의 고유한 기능을 변화시켜서 구강건조감, 구강작열감, 다발성 치아우식증 등의 소인이 된다. 이에 저자는 심리적 요인이 구강내 환경에 미치는 영향을 평가하고자 타액선질환을 포함한 전신질환이 없는 전북대학교 치과대학생 20명을 대상으로 일상생활시와 시험 직전의 비자극성 전타액을 5분간 추출하여, 그 유출량과 수소이온농도를 측정, 비교, 평가하였다. 타액유출량은 $25m{\ell}$의 메스실린더를 사용하였고, 수소이온농도는 pH/SEmeter(ORION, 720A model)를 이용하여 측정하였다. 평가 결과 남성의 비자극성 타액유출량과 수소이온농도는 $3.68{\pm}1.31m{\ell}/5min$와 $7.63{\pm}0.17$이었고, 여성에서는 각각 $4.93{\pm}1.47m{\ell}/5min$와 $7.43{\pm}0.29$로서 성별간 유의한 차이가 없었다. 그리고 일상생활시의 성인의 5분간 수집된 비자극성 타액유출량은 $4.18{\pm}1.48m{\ell}/5min$였고, 스트레스하에서의 양은 $2.20{\pm}0.95m{\ell}/5min$로 나타나 스트레스시 타액유출량이 감소하는 것으로 나타났다(p<0.01). 또한 일상생활시의 성인의 비자극성 타액의 수소이온농도는 $7.55{\pm}0.24$였고, 스트레스하에서의 수소이온농도는 $7.22{\pm}0.20$으로 나타나 스트레스시 수소이온농도가 감소하는 것으로 나타났다(p<0.01). 이상의 결과로 보아 스트레스는 타액유출량을 감소시키고 구강내를 보다 산성화시킨다고 사료된다.

한약재 수치에 관한 연구 (V) - 갈근의 수치전.후 Puerarin의 함량분석 및 시험관내에서 최종당화산물 생성억제 효능 -

김현정,김진숙,Kim, Hyeun-Jeong,Kim, Jin-Sook 한국한의학연구원 2003 한국한의학연구원논문집 Vol.9 No.1

Advanced glycation end products(AGEs) are largly involved in the pathogenesis of diabetic complications. It is obvious that inhibition of AGEs formation is important in preventing the occurrence and progression of diabetic complications. Therefore, to seek possible AGEs inhibitors in herbal medicines, unprocessed - und processed Puerariae Radix were tested. The inhibitory effect on AGEs formation was slightly increased through processing. Unprocessed-, processed Puerariae Radix and puerarin showed potential inhibitory action than that of positive control, amino guanidine HCI.

차잎의 초기 성장 시기 동안 lipoxygenase 활성 및 휘발성 향기성분의 변화

김현정,류성권,노진철,이상준,박승국,Kim, Hyun-Jeong,Ryu, Sung-Kwon,Roh, Jin-Chul,Lee, Sang-Jun,Park, Seung-Kook 한국응용생명화학회 2003 한국농화학회지 Vol.46 No.1

Lipoxygenase는 녹차의 전체적인 품질에 영향을 미치는 "신선하고 풋풋한 풀 향기(green odor)" 향기특성을 가지는 $C_6-alcoho$과 $C_6-aldehyde$ 등 $C_6$화합물을 생성시키는데 관여하는 효소로서 잘 알려져 있다. 본 연구에서는 녹차잎의 초기 성장기간인 4뭘 4에서 15일까지 12일 동안에 매일 채엽한 녹차잎의 lipoxygenase 활성을 측정하고, 이에 따른 $C_6$화합물 및 terpene 등 휘발성 향기성분을 분석하여 수확 날짜에 따른 효소 활성과 녹차잎의 중요한 휘발성 향기성분의 변화를 살펴보았다. 효소활성의 측정은 linoleic acid를 기질로 한 흡광도 측정방법을 사용하였고, 휘발성 향기성분은 Solid Phase MicroExtraction (SPME) 방법으로 휘발성 향기성분을 포집한 후에 GC또는 GC-MS를 이용해 분석하였다. 실험 결과, 초기 녹차 잎 성장기간 동안 lipoxygenase 활성과 $C_6$화합물의 함량은 서로 비례하여 증가 또는 감소하였고, 이러한 변화는 당일의 온도변화와 밀접한 관계가 있는 것으로 나타났다. 즉, 온도가 증가함에 따라서 향기성분의 양도 증가하였으며, 너무 이른 시기에 채엽한 시료는 향기 성분이 매우 적은 것으로 나타났다. 본 연구로부터 "신선한 풀향기"와 "향긋한 꽃향기 (floral)" 등 녹차향 품질에 중요한 영향을 미치는 향 화합물들이 녹차의 초기 채엽기간 중에 어떻게 변화하는지에 대해서 확인 할 수 있었으며, 향기품질이 우수한 녹차를 제조하기 위해서는 생엽 성장 기간동안의 향기성분변화를 이해하는 것이 중요하다는 것을 확인하였다. Lipoxygenase is the enzyme responsible for the formation of $C_6$-alcohols and $C_6$-aldehydes ($C_6$-compounds), which are well blown contributors to various types of 'green odor' In green tea. Changes in lipoxygenase activity and volatile compounds of green tea leaves were monitored daily during early growing season. The enzyme activity was spectrophotometrically measured using linoleic acid as a substrate. The volatile compounds were extracted through Solid Phase Micro-Extraction, and were subjected to GC and GC-MS analyses. Results showed that lipoxygenase activity and levels of $C_6$-compounds concomitantly increased or decreased during the early growing season, probably caused by the fluctuation in the daily temperature; increase in temperature led to the increase in enzyme activities and $C_6$-compound levels, whereas leaves plucked too early had low volatile compound levels. In this study, optimum plucking time of tea leaves for the production of high quality green tea with a wellbalanced aroma was determined.

Sulforaphane의 Human MCF-7 Mammary 종양세포 유사분열의 억제 및 Tubulin의 중합화 저해

김현정,Kim, Hyeon-Jeong 한국식품연구원 2004 食品技術 Vol.17 No.4

Sulforaphane은 브로컬리나 십자화과 채소중의 glucoraphanin의 가수분해 산물인 isothiocyanate로서 이는 detoxification 효소의 phase II를 일으키는 것으로 나타났고 설치류에서 화학적으로 발생된 유선 종양을 억제하고 최근에는 대장암 세포에서 cell cycle arrest와 apoptosis를 일으킨다고 알려져 왔다. 여기서는 SUL이 Human MammaryMCF-7 adenocarcinoma 세포의 증폭을 억제하는 역할을 제시하였다. MCF-7 cell에 15umol/L SUL을 처리하였을 때 G2/M cell cycle이 arrest를 보였고 cyclin B1 protein이 24시간 이내에 증가하였다. 15umol/L의 SUL은 in vivo 상에서 histon Hl의 인산화를 유도하고, 초기 mitosis에서 cell을block하며 mitotic microtuble의 중합화를 방해하였다. In vitro 상에서 정제된 bovine braintubulin에 대한 SUL을 고농도로 투여했을 때, tubulin의 중합율과 총 tubulin 중합도의 억제를 보였다. 덧붙여서, isothiocyanate를 함유하는 SULanalog로 처리된 정제 tubulin도 비슷하게 저해를 받았다. 본 연구는 SUL이 mitotic cell cyclearrest를 포함한 mammary cancer 억제력을 가진 것과, 이러한 기작으로 정상적인 tubulin 중합화및 microtubule dynamic에 한층 효과적인 영향을 준다는 것을 제시하였다.