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      • SCOPUSSCIEKCI등재

        모야모야병에서 염기성 섬모 세포 성장 인자의 역할

        김동석,최중언,김세혁,양국희,김현숙,Kim, Dong-Seok,Choi, Joong-Uhn,Kim, Se-Hyuk,Yang, Kook-Hee,Kim, Hyeun-Sook 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.1

        Objectives and Importance : The present study investigated the levels of basic fibroblast growth factor(bFGF) in the CSF of patients with moyamoya disease and its clinical significance. Methods : The levels of bFGF in CSF, taken from 26 hemispheres of 14 moyamoya patients and 20 patients without vascular anomaly(control group), were measured by an enzyme-linked immunosorbent assay. We analyzed the correlation between the level of bFGF and the clinical factors such as age, onset pattern, development of neovascularization, and cerebral circulation. Results : The CSF of moyamoya patients contained a high concentration of bFGF to a significant extent. The bFGF level was apparently elevated in the patients in whom neovascularization from indirect revascularization, such as modified encephalo-duro-arterio-synangiosis(EDAS) was well developed. A linear correlation between the values of bFGF and clinical progression was noted. Conclusions : The elevation of bFGF in moyamoya disease seems to be specific. Clinically, the bFGF level may be considered a useful indicator to predict the efficacy of indirect revascularization.

      • 유방암의 Imprint 표본에서 p53 단백 발현

        김동석,이은희,김기권,김미진,이수정,Kim, Dong-Sug,Lee, Eun-Hi,Kim, Ki-Kwon,Kim, Mi-Jin,Lee, Soo-Jung 대한세포병리학회 1995 대한세포병리학회지 Vol.6 No.1

        This study was carried out to determine the usefulness of imprint cytology for detecting p53 protein in breast carcinoma. NCL-DO7 (Novocastra, U.K.) was used to detect p53 protein immunocytochemically. A total of 33 cases was studied, Immunostaining of imprint cytology with NCL-DO7 was positive in 64% (21/33) and showed relatively high coincident rate (80%) with immunostaining of formalin-fixed, paraffin-embedded specimen p53 protein was related to negative estrogen receptor status, but not to the nuclear grade, lymph node metastasis, or tumor size. The fact that p53 protein expression was not related to nuclear grade might be due to predominance of nuclear grade 3. It was easier to determine the nuclear grade is one of the most important prognostic factors, in imprint cytology than in tissue specimen. p53 protein tended to be stained more strongly in imprint cytology than in tissue. It is concluded that the application of imprint cytology in p53 protein detection can be performed easily, and that it may contribute to the evaluation of prognostic factors in breast carcinoma.

      • KCI등재

        임펄스 UWB 네트워크에서의 일정진폭 다중접속 채널코딩

        김동석(Tongsok Kim),김용철(Yong Cheol Kim) 대한전자공학회 2008 電子工學會論文誌-SC (System and control) Vol.45 No.6

        이 논문은 임펄스 UWB 시스템을 위한 새로운 일정진폭 프리코딩을 제안한다. IEEE 802.15.4a 표준에 따르면 임펄스 UWB는 실내측위와 센서 데이터 전달에 사용될 수 있다. 대부분의 USN(ubiquitous sensor network)은 다중접속을 필요로 한다. 그러나 UWB 시스템은 다중접속으로 야기되는 중첩신호를 검출하는데 있어 제약성이 있다. 이를 극복하기 위하여 Wada 및 Kim의 CAMC(constant amplitude multi-code) 개념을 응용하였다. 제안하는 시스템은 체계적 일정진폭 프리코딩과 LDPC 디코딩으로 구성된다. 또한 컴퓨터 시뮬레이션을 통하여 BER 성능이 우수함을 확인하였다. In this article a novel constant amplitude precoding for impulse UWB system is proposed. According to IEEE 802.15.4a, impulse UWB can be used in indoor localization and sensor data transmission. Most USN(ubiquitous sensor networks) needs multiple access. However impulse UWB system has a limited capability to detect superpositioned signal induced by multiple access. To overcome this problem we have adopted the concept of CAMC(Constant Amplitude Multi-Code) deviced by Wada and Kim. The proposed system consists of systematic constant amplitude precoding and LDPC decoding. And this system shows a good BER performance in computer simulation.

      • KCI등재

        LNG Tank용 자기충전 콘크리트의 배합설계에 관한 연구

        김동석,박상준,원철,이상수,Kim, Dong-Seok,Park, Sang-Joon,Won, Cheol,Lee, Sang-Soo 한국건축시공학회 2003 한국건축시공학회지 Vol.3 No.4

        The purpose of this study was to design the self-compaction concrete mixture, having not only high strength but also compensation of shrinkage without thermal crack under 4 sides outer restraint of the member. In the experimental mix, replacement ratio of limestone Powder, CSA expansive additives, and unit water were selected as parameters, using portland blast-furnace slag cement. And, bleeding test, expansibility test, hydration heat analysis were performed. As a results, when 35% of limestone Powder, 6% CSA expansive additives are replaced at unit water 175kg/$\textrm{m}^3$, demanded performances of fresh and hardened self-compaction concrete are accomplished.

      • KCI등재

        스펀지에 고정한 광촉매를 이용한 안료의 탈색

        김동석,박영식,Kim, Dong-Seog,Park, Young-Seek 한국환경보건학회 2005 한국환경보건학회지 Vol.31 No.5

        The photocatalytic decolorization of Reactive Red 2B(RR2B) was studied using immobilized photocatalyst/UV System. Two pairs of 20 W UV-B and UV-C lamps were employed as the light source. Immobilization of $TiO_2$ was carried out using sponge (as the photocatalyst body) and silicone sealant(as the binder). The effects of parameters such as the thickness, pore size of sponge photocatalyst and attached material on the reactor bottom were investigated. The results showed that the optimum thickness of sponge photocatalyst was 1 cm. Decolorization of reactor which had the bottom coated $TiO_2$ was higher than that of reactor attached aluminum plate. Decolorization of photocatalyst with large pore size(mean pore size, 3.8 mm) was higher than that of the small(mean pore size, 1.75 mm). Initial decolorization of RR2B could be descrived using the Langmuir-Hinshelwood(L-H) model and gave constant values of $0.55mg/l{\cdot}min(k)\;and\;2.65{\times}10^{-2}l/mg(K)$, respectively.

      • KCI등재

        내관$(PC_6)$의 황련해독탕 약침이 EEG 변화에 미치는 효과

        김동석,이상룡,Kim, Dong-Seok,Lee, Sang-Ryong 경락경혈학회 2004 대한침구의학회지 Vol.21 No.3

        Objectives : The aim of this study was to examine the effects of Hwangryunhaedoktang Herbal acupuncture at the PC6(Naegwan) on the EEC of normal human being by using power spectral analysis. Methods : EEC power spectrum exhibit site-specific and state-related differences in specific frequency bands. In this study, power spectrum was used as a measure of complexity. 32 channel EEC study was carried out in 11 subjects (11 males; age=27.8 years). Results : In ${\alpha}(alpha)$ band, the power values at T3, TT1, CP1, T5, Po2, O1, Oz channels(p<0.05) during the PC6-acupoint treatment were increased significantly. In ${\beta}(beta)$ band, the power values at TT1, CP1, T5, P3, Po2, O1, Oz channels(p<0.05) during the PC6-acupoint treatment were increased significantly. In ${\theta}(theta)$ band, the power values at T3, TT1, CP1, Po2, O1, Oz channels(p<0.05) during the PC6-acupoint treatment were increased significantly. In ${\delta}(delta)$ band, the power values at F4, T3, CP1, O1, Oz, O2 channels(p<0.05) during the PC6-acupoint treatment were increased significantly. Conclusions : This results suggest that Hwangryunhaedoktang Herbalacupuncture at the PC6 is significantly in ${\alpha}(alpha)$ band.

      • KCI등재

        0.25 ㎛ GaAs pHEMT 공정을 이용한 X-대역 코아-칩의 설계

        김동석,이창대,이동현,염경환,Kim, Dong-Seok,Lee, Chang-Dae,Lee, Dong-Hyun,Yeom, Kyung-Whan 한국전자파학회 2018 한국전자파학회논문지 Vol.29 No.5

        We herein present the design and fabrication of a Rx core chip operating in the X-band (10.5~13 GHz) using Win's commercial $0.25-{\mu}m$ GaAs pHEMT process technology. The X-band core chip comprises a low-noise amplifier, a four-bit phase shifter, and a serial-to-parallel data converter. The size is $1.75mm{\times}1.75mm$, which is the state-of-the-art size. The gain and noise figure are more than 10 dB but less than 2 dB, and both the input and output return losses are less than 10 dB. The RMS phase error is less than $5^{\circ}$, and the P1dB is 2 dBm at 12.5 GHz, the performance of which is equivalent to other GaAs core chips. The fabricated core chip was packaged in a QFN package type with a size of $3mm{\times}3mm$ for the convenience of assembly. We confirmed that the performance of the packaged core chip was almost the same as that of the chip itself. 본 논문에서는 Win 사의 상용 $0.25{\mu}m$ GaAs pHEMT 공정 기술을 이용하여 X-대역(10.5~13 GHz)에서 동작하는 수신부 코아-칩의 설계 및 제작을 보였다. X-대역 코아-칩은 저잡음증폭기, 4-비트 위상천이기, 직렬-병렬 컨버터(SPC: Serial to parallel data converter)로 구성되며, 크기는 $1.75{\times}1.75mm^2$로 지금까지 보고된 코아-칩 중 가장 소형의 크기를 갖는다. 사용 주파수 대역에서 이득 및 잡음지수는 각각 10 dB 이상, 2 dB 미만, 입출력 반사손실은 10 dB 미만이다. RMS 위상 오차는 12.5 GHz에서 $5^{\circ}$ 미만, P1dB는 2 dBm으로 타 코아-칩과 대등한 성능을 갖는다. 제작된 코아칩은 조립의 편의를 제공하기 위해 $3{\times}3mm^2$ 크기를 갖는 QFN 패키지로 패키지되었으며, 패키지된 코아-칩의 성능은 칩-자체의 성능과 거의 같음을 확인하였다.

      • KCI등재

        응집과 균질화가 팽화슬러지의 용존공기부상과 침전에 미치는 영향

        김동석,박영식,Kim, Dong-Seog,Park, Young-Seek 한국환경보건학회 2007 한국환경보건학회지 Vol.33 No.1

        The objective of this study is to examine the effect of the coagulation and homogenization in bulking sludge thickening of paper manufacturing plant using DAF(Dissolved Air Flotation) and gravitational sedimentation. The effects of parameters such as dosage of coagulant and homogenization time were examined. The results showed that DAF and sedimentation was affected aluminum sulfate and anion polymer coagulant differently. At the optimum dosage of aluminum sulfate, thickening efficiency of DAF and sedimentation process were increase 1.25 time and 2.02 time, respectively. At the optimum dosage of anion polymer coagulant, thickening efficiency of DAF process was increase 1.35 time, but thickening efficiency at sedimentation was 1.06 time. When anion polymer coagulant of 0.5 mg/l was added in DAF process, water content of sludge was decreased from 96.6% to 90.7% in dewatering process using Buchner funnel test device. After homogenization(20500 rpm, 10 min), Sauter mean diameter of sludge floc was decreased from 631 ${\mu}m$ to 427 ${\mu}m$, however increase of flotation efficiency by DAF was only 1.09 time.

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