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김지욱,Lee A Ran,Park Eun Sun,Yun Minsu,Ryu Sung Won,Kim Uk Gwan,강동희,Kim Ju Deok 대한마취통증의학회 2022 Anesthesia and pain medicine Vol.17 No.1
Background: This study assessed the effect of a single bolus administration of lidocaine on the prevention of tourniquet-induced hypertension (TIH) and compared the effect of lidocaine to that of ketamine in patients undergoing general anesthesia.Methods: This randomized, controlled, double-blind study included 75 patients who underwent lower limb surgery using a tourniquet. The patients were administered lidocaine (1.5 mg/kg, n = 25), ketamine (0.2 mg/kg, n = 25) or placebo (n = 25). The study drugs were administered intravenously 10 min before tourniquet inflation. Systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were measured before tourniquet inflation, after tourniquet inflation for 60 min at 10 min intervals, and immediately after tourniquet deflation. The incidence of TIH, defined as an increase of 30% or more in SBP or DBP during tourniquet inflation, was also recorded.Results: SBP, DBP, and HR increased significantly over time in the control group compared to those in the lidocaine and ketamine groups for 60 min after tourniquet inflation (P < 0.001, P < 0.001, and P = 0.007, respectively). The incidence of TIH was significantly lower in the lidocaine (n = 4, 16%) and ketamine (n = 3, 12%) group than in the control group (n = 14, 56%) (P = 0.001). Conclusion: Single-bolus lidocaine effectively attenuated blood pressure increase due to tourniquet inflation, with an effect comparable to that of bolus ketamine.
ECONOMIC GROWTH AND TECHNOLOGY DIFFUSION IN DEVELOPING COUNTRIES
김지욱 한국경제학회 2008 The Korean Economic Review Vol.24 No.2
This paper aims to use the system-GMM estimation to fit an augmented Solow growth model with international technology diffusion variables. We also investigate whether the parameters of the model differ appreciably across subsamples of countries. The paper finds that foreign direct investment is a more important channel for technology transfer to developing countries than openness to international trade. Furthermore, the estimates indicate that the more rapidly technology transfer is made, the greater is the stock of human capital accumulated. This paper aims to use the system-GMM estimation to fit an augmented Solow growth model with international technology diffusion variables. We also investigate whether the parameters of the model differ appreciably across subsamples of countries. The paper finds that foreign direct investment is a more important channel for technology transfer to developing countries than openness to international trade. Furthermore, the estimates indicate that the more rapidly technology transfer is made, the greater is the stock of human capital accumulated.
김지욱,이성진 순천향대학교 순천향의학연구소 2012 Journal of Soonchunhyang Medical Science Vol.18 No.2
A 56-year-old female patient presented with decreased visual acuity in her right eye lasting for one day. During the first visit, best corrected visual acuity (BCVA) was 20/80 and 20/20, in the right and left eye, respectively. Fundus examination of the right eye revealed an elevated mass in the superior area of the optic disc and exudative retinal detachment in the macula. Choroidal metastatic tumor secondary to non-small-cell lung cancer (NSCLC) was diagnosed after systemic work up. Photodynamic therapy (PDT) and the intravitreal bevacizumab injection for choroidal metastatic carcinoma were performed. After six months, the BCVA of the right eye was improved to 20/25. Complete regression of the tumor was noticed and serous detachment was resolved. There has been no recurrence for six months. We observed that combined treatment with PDT and intravitreal bevacizumab injection is effective in BCVA improvement and tumor regression, in a patient with choroidal metastasis of NSCLC.
2P-548 The influence of β-resin content of the binder pitch on density of carbon block
김지욱,김경훈,이상민,조한주,이영석 한국공업화학회 2017 한국공업화학회 연구논문 초록집 Vol.2017 No.1
A binder pitch is important to manufacture a carbon block and a bulk graphite due to little binding ability. However, there is a lot of weight-loss during carbonization process. This results in low density of carbon block. In this paper, we prepared binder pitches from pyrolysis fuel oil with different β-resin content and with similar quinoline-insoluble content and softening point. Aromaticity of the binder pitches increased by increasing β-resin content from 0.78 to 0.81. To prepare the pitch/coke block, the binder pitches and commercial isotropic coke were mixed in a weight ratio of 2:8 at room temperature, and the mixture was compressed at 100MPa at 150°C for 15min using cylinder shaped metal mold. Then, the carbon block was prepared from the pitch/coke block through carbonization at 1,000°C. Density of the carbon block increased up to 4.6% by increasing β-resin content. It is attributed that the β-resin content affect to increase the carbon block density during heating process
김지욱,최연주,이승엽,최경식 대한안과학회 2013 Korean Journal of Ophthalmology Vol.27 No.4
Purpose: To evaluate the clinical usefulness of binocular multifocal electroretinography (mfERG) by comparing results with conventional monocular mfERG in patients with monocular macular disease. Methods: mfERG testing was conducted on 32 patients with monocular macular disease and 30 normal subjects. An initial mfERG was simultaneously recorded from both eyes with two recording electrodes under binocular stimulation. A second mfERG was subsequently recorded with conventional monocular stimulation. Amplitudes and implicit times of each ring response of the binocular and monocular recordings were compared. Ring ratios of the binocular and monocular recording were also compared. Results: In the macular disease group, there were no statistical differences in amplitude or implicit time for each of the five concentric rings between the monocular and binocular recordings. However, with binocular simulation, the ring ratios (ring 1 / ring 4, ring 1 / ring 5) were significantly reduced in the affected eye. In the normal control group, there were no statistical differences in any parameters between the monocular and binocular recordings. Conclusions: Binocular mfERG could be a good alternative to the conventional monocular test. In addition,given that the test needs stable fixation of the affected eye during the binocular test, the reliability of the test results could be improved, especially for patients with monocular macular disease
Change of inspired oxygen concentration in low flow anesthesia
김지욱,Kang Donghee,Lee Hochul,Ryu Sungwon,Ryu Siejeong,Kim Doosik 대한마취통증의학회 2020 Anesthesia and pain medicine Vol.15 No.4
Background: There are several advantages of low flow anesthesia including safety, economics, and eco-friendliness. However, oxygen concentration of fresh gas flow and inspired gas are large different in low flow anesthesia. This is a hurdle to access to low flow anesthesia. In this study, we aimed to investigate the change in inhaled oxygen concentration in low flow anesthesia using oxygen and medical air.Methods: A total of 60 patients scheduled for elective surgery with an American Society of Anesthesiologist physical status I or II were enrolled and randomly allocated into two groups. Group H: Fresh gas flow rate (FGF) 4 L/min (FiO₂ 0.5). Group L: FGF 1 L/min (FiO₂ 0.5). FGF was applied 4 L/min in initial phase (10 min) after intubation. After initial phase FGF was adjusted according to groups. FGF continued at the end of surgery. Oxygen and inhalation anesthetic gas concentration were recorded for 180 min at 15 min interval.Results: The inspired oxygen concentration decreased by 5.5% during the first 15 min in the group L. Inspired oxygen decreased by 1.5% during next 15 min. Inspired oxygen decreased by 1.4% for 30 to 60 min. The inspired oxygen of group L is 35.4 ± 4.0% in 180 min. The group H had little difference in inspired oxygen concentration over time and decreased by 1.8% for 180 min.Conclusions: The inspired oxygen concentration is maintained at 30% or more for 180 min in patients under 90 kg. Despite some technical difficulties, low flow anesthesia may be considered.