아메드 밸브 삽입술 후 장치의 노출에 대해 보존 대퇴근막 이식으로 치료한 1예

박가희,하승주 순천향대학교 순천향의학연구소 2011 Journal of Soonchunhyang Medical Science Vol.17 No.2

We report one case of implant plate exposure after Ahmed valve implantation, treated with preserved fascia lata transplantation. Exposure of implant occurred in 47-year-old patient with Ahmed glaucoma valve implantation. She was treated with preserved fascia lata graft and amniotic membrane transplantation. No recurrent implant plate exposure has been found since then. Intraocular pressure has been maintained well for 3 months of follow-up. In cases of implant plate exposure, additional preserved fascia lata graft and amniotic membrane transplantation can improve surgical success.

병원성 미생물에 대한 약산성 차아염소산수 네오록스의 살균소독력 평가

방해인,최태윤 순천향대학교 순천향의학연구소 2016 Journal of Soonchunhyang Medical Science Vol.22 No.2

Objective: Disinfection/sterilization of hospital devices prevents the occurrence of several infections; therefore, disinfectants are essential for public health. The purpose of this study was to evaluate the biocidal effect of a hypochlorous acid solution. Methods: Hypochlorous acid solution, Neolox (Neo Chemical, Paju, Korea) obtained from Purester (Morinaga Engineering, Tokyo, Japan) was used. Antimicrobial activity of the solution against bacteria, yeasts, and mycobacteria at different exposure times (0.5, 1, 2, 5, 10, 15, and 30 minutes) was evaluated. Results: All strains of bacteria and yeasts showed a 5-log10 reduction within 30 seconds of exposure to the solution, and mycobacteria showed the same reduction within 2 minutes. Conclusion: Hypochlorous acid solution has been widely used as a disinfectant in recent years. Neolox can be used as an effective intermediate- to high-level disinfectant for hospital infection control.

근육 강직 증후군의 성공적인 치료 1예

김상현,석현 순천향대학교 순천향의학연구소 2011 Journal of Soonchunhyang Medical Science Vol.17 No.2

Stiff man syndrome is a rare neurological condition characterized by progressive muscle stiffness and rigidity, painful spasm of axial and limb muscles with impairment of walking. Because its etiology is still unclear, diagnosis is based on typical clinical manifestations. Benzodiazepines are known as effective drug for the treatment of symptoms. We report a case of 39-year-old female patient who has suffered from rigidity of trunk, back pain, gait disturbance and depressive mood for 18 months. She was diagnosed as stiff man syndrome and successfully treated with medications such as diazepam, clonidine, baclofen.

벨마비 후 촉각자극과 씹기에 의해 유발되는 반대측 삼차신경통

김승주,박덕수,정두신,양광익,박형국,오형근 순천향대학교 순천향의학연구소 2013 Journal of Soonchunhyang Medical Science Vol.19 No.1

We report a 43-year old woman patient presented with contralateral trigeminal neuralgia induced by tactile stimulation and mastication after Bell’s palsy. Trigeminal neuralgia is characterized by recurrent episodes of intense lancinating pain affecting the face localized to the sensory supply areas of the trigeminal nerve. Increased excitability of facial motor neurons and bainstem interneurons which mediate trigemio-facial reflex are thought to be the cause of contralateral trigeminal neuralgia after Bell’s palsy.

생체 간이식 후에 발생한 비장동맥 스틸증후군의 성공적인 치료 1예

정재홍 순천향대학교 순천향의학연구소 2019 Journal of Soonchunhyang Medical Science Vol.25 No.2

Splenic artery steal syndrome (SASS) after orthotopic liver transplantation (OLT) has been recently described as hepatic artery hypoperfusion secondary to the portal hyperperfusion. It is an uncommon but serious complication of OLT. Left untreated, it leads to postoperative morbidity or graft loss. Herein we report the case of a 52-year-old female who suffered from SASS following living donor liver transplantation. She was diagnosed by angiography and successfully managed by splenic artery embolization. Splenic artery embolization for the treatment of SASS is a safe and effective modality.

급성 뇌경색 환자에서 심초음파 좌심방 확장소견과 입원 중 심방세동 발견의 연관성

이경복,김지선,노학재,안무영,박병원,현민수 순천향대학교 순천향의학연구소 2015 Journal of Soonchunhyang Medical Science Vol.21 No.2

Objective: Longstanding hypertension lead to left ventricular diastolic dysfunction with a development of a left atrial enlargement (LAE) which may result in vulnerability to atrial fibrillation (AF). Paroxysmal AF is usually unrevealed in the acute period of ischemic stroke, but is crucial for anticoagulation to prevent recurrent stroke. This study was aimed to investigate the frequency of LAE and the predictors of paroxysmal AF during the hospitalization of acute ischemic stroke. Methods: A total 1,643 consecutive patients with acute ischemic stroke were registered in between January 2005 and December 2014. The subjects who had AF before index stroke or at admission were excluded. The clinical and echocardiographic findings of all patients were reviewed. Paroxysmal AF were detected on electrocardiography of Holter monitoring during hospitalization. LAE were defined as LA diameter larger than 44 mm in echocardiography. We compared the frequency of LAE between the patients with or without AF. Logistic regression analysis were performed to determine the echocardiographic parameters for prediction of paroxysmal AF. Results: The mean age was 67.3 and the male was 55.6%. AF were detected in 123 (11.4%) of LAE(-) group but were detected in 102 (49.0%) in LAE(+) group. In logistic regression analysis, LAE significantly predicted for newly detected AF during hospitalization after adjusting covariates (odds ratio, 5.698; 95% confidence interval, 3.799-8.546; P<0.001). Conclusion: LAE was an independent predictor for AF during hospitalization in patients with acute ischemic stroke. Prolonged electrocardiography monitoring should be meticulously indicated for acute ischemic stroke with LAE to detect paroxysmal AF.

Uterine Cervix Metastasis in Lung Adenocarcinoma with Anaplastic Lymphoma Kinase Rearrangement

Sooa Choi,Chan Kwon Park,Shin Young Kim,Hyoung Kyu Yoon,Sang Mi Ro,Yunju Nam 순천향대학교 순천향의학연구소 2015 Journal of Soonchunhyang Medical Science Vol.21 No.2

The importance of anaplastic lymphoma kinase (ALK) as an oncogene in non-small cell lung cancer (NSCLC) has emerged as a major concern due to a dramatic clinical effect of targeted therapy. As compared with the research for targeted therapy, the study about clinicopathological characteristics for ALK positive NSCLC hasn’t been worked enough. Here, we describe a 35-year-old woman diagnosed with stage IVb NSCLC with ALK rearrangement. During evaluating her disease, a metastatic lesion to uterine cervix was found. Although lung cancer metastasis to female genital tract is rare, we also present case series that show a metastasis to the female genital tract in NSCLC with ALK rearrangement. These case series could suggest that ALK positive NSCLC has distinct metastatic pattern.

Two Cases of Complications during Percutaneous Coronary Intervention for Myocardial Infarction in Patients with Concurrent Chronic Total Occlusion in an Emergency Setting

Donghoon Han,Sehun Kim,Sang Jun Park,Jae Hyuk Choi 순천향대학교 순천향의학연구소 2018 Journal of Soonchunhyang Medical Science Vol.24 No.2

Morbidity and mortality rates associated with acute myocardial infarction accompanying chronic total occlusion are comparatively high. European guidelines recommend primary intervention for the causative lesion in patient with acute myocardial infarction. Therefore, it is important to identify the culprit lesion. We report two cases of myocardial infarction with concurrent chronic total occlusion in an emergency setting.

Evans Syndome 환자의 제왕절개술 시 마취 경험

조아나 순천향대학교 순천향의학연구소 2019 Journal of Soonchunhyang Medical Science Vol.25 No.2

Evans syndrome is an uncommon condition defined by the combination of immune thrombocytopenia and autoimmune hemolytic anemia in the absence of known underlying cause. Association of Evans syndrome with pregnancy is very rare, and only a few cases have been published in the medical literature. We experienced a case of Evans syndrome in pregnancy. Cesarean section was performed under general anesthesia without hemorrhagic complications at the 37th week of pregnancy following treatment with steroid, intravenous immunoglobulin, and transfusion of platelet concentrates. We have also briefly discussed the pathophysiology, the possible treatment options during pregnancy and prenatal outcome of Evans syndrome.

전립선 특이항원과 체질량지수 및 허리둘레의 연관성

이 진,신황식,조용진,오정은 순천향대학교 순천향의학연구소 2021 Journal of Soonchunhyang Medical Science Vol.27 No.2

Objective Prostate-specific antigen (PSA) is widely used as a screening tool of prostate cancer, although there has been a controversy about efficacy. In Korea, rapid growth of obesity prevalence in adult men is a one of the biggest health problems. The objective of this study was to evaluate the potential association between body mass index (BMI), waist circumference (WC) and PSA. Methods We calculated BMI and WC of a total of 25,603 males who visited the Soonchunhyang University Cheonan Hospital Health Promotion Center from January 2016 to December 2020. This was categorized as follows: BMI < 23 kg/m2 (normal), 23 kg/m2 ≤ BMI < 25 kg/m2 (overweight), BMI ≥ 25 kg/m2 (obesity) and WC < 90 cm (normal), WC ≥ 90 cm (abdominal obesity). We analyzed the association between BMI, WC and PSA. Results The mean PSA value was 1.08 ng/mL, 1.03 ng/mL, and 0.97 ng/mL at normal, overweight, and obesity group, respectively. The mean PSA value was 1.04 ng/mL and 0.96 ng/mL at normal and abdominal obesity group. Thus, the mean PSA value decreased with an increase in BMI and WC category (P < 0.001). The correlation coefficient between BMI, WC and PSA was -0.055, -0.044 and they were statistically significant (P < 0.001). Conclusion We observed a significant negative correlation between BMI, WC and PSA value. Therefore, PSA value should be considered in relation to BMI and WC.