방사선조사가 백서 법량질형성 과정에 미치는 영향에 관한 연구

최순철,유동수,최현배,박태원 大韓口腔顎顔面 放射線學會 1997 Imaging Science in Dentistry Vol.27 No.1

The purpose of this study was to investigate the radiation effect on the stages of amelogenesis. Twenty 11-day-old rats which were irradiated by 4Gy of gamma radiation on the 19th prenatal day were used for the experimental group and twenty 11-day-old rats which were not irradiated were used for the control group. The length of each zone of amelogenesis were measured on the sagittal section using a light microscopic enlargement at 400 x the normal view while the morphologic changes of ameloblasts of each zone were observed electron-microscopically. The obtained results were as followed: 1. The length of the region of facing pulp and facing dentin of the zone of presecretion were increased by 11.5%(p<0.05) and 17.7%(p<0.01), respectively. 2. The length of the zone of secretion was increased by 17.3%(p<0.01), but the zone of maturation was decreased by 15.3%(p<0.01). 3. The total length of the zone of amelogenesis was not changed significantly(p>0.05). 4. Electron-microscopically, enlargement of the cell membrane, rER, mitochondria, and nuclear membrane were observed. These changes were mostly severe in the zone of maturation.

한국인의 한방의료이용에 대한 인식과 행태 요인 분석

박성순,남철현 대한보건협회 1999 대한보건연구 Vol.25 No.2

본 논문은 국민들의 한방의료요구와 이용실태를 파악하여 보다 효율적인 한방정책수립에 기여할수 있도록 기초자료 제공에 목적을 두고, 1998년 3월 2일부터 5월 31까지 3개월간 대도시와 중소도시 지역주민 1,116명을 조사한 결과 주요 요약과 결론은 다음과 같다. 1) 지금까지 질병별 한방의료이용을 한 응답자는 75.8%였으며, 1~4회가 36.2%로 가장 높았고, 이상은 l5.4%였다. 민간요법경험자는 27.8%였고 앞으로 사용해 보겠다가 44.3%였다. 2) 한방진료후 만족도는, 만족한다가 53.2%, 보통이 39.6%, 불만족이 7.2%였으며, 만족한다는 군은 남자에서, 60세 이상에서. 고등학교 졸업자에서, 무직자에서, 불교신자에서, 대도시 거주자에서 각각 타군보다 높았다. 3) 한방에 대한 기본지식은 14점 만점에 5.43±2.52점으로 낮은 수준이다. 4) 한방의료이용에 영향을 미치는 요인은 연령, 한방진료만족도, 불건강시 한방진료에 대한 대처태도, 결혼상태, 교육정도, 직업 등의 변수들이었다. 이상에서와 같이 한방의료이용에 대한 국민들의 기대와 신뢰감이 높아서 이용율은 높아는 가고 있지만, 한방의료에 대한 지식수준은 너무 낮아서 한방의료관련 당국이나 단체, 그리고 한의계 종사자들이 TV, 라디오, 신문 등의 매체를 통한 대국민 홍보, 교육용 프로그램등을 개발하여 국민들이 올바른 지식을 가지고 한방의료를 적절히 이용하도록 함으로써, 건강증진에 기여해야 할 것이다. 또한 한방의료비가 비싸다는 의견과 복용하기가 불편하다, 가리는 것이 많다, 한약의 과학성이 적다는 응답율이 높은 비율을 보이고 있어서, 이에 대한 대책으로 한방의료기술의 현대화와 한방의료보험·확산적용, 한약재의 표준화, 규격화, 의료비의 적정화 등, 획기적인 한방의료정책이 조속히 수립되어야만 될 것이라고 생각한다. The purpose of this study was to investigate actual status of oriental health care utilization and its determinants. Data were collected by trained college students through questionnaire during a period of 3 months from March 2nd to May 31st, 1998. The subjects served for this study consisted of 1,116 persons who had resided in big cities and small and medium sized cities in Korea. The results were summarized as follows: 1. In regard to patient's utilization of Oriental medicine, most of respondents(75.8%) had utilized oriental medicine, 32.6% among them reported 1-4 times of Oriental institution utilization and 15.4% in over 10 times. 2. The reasons for the utilization of Oriental medical care were 31.3% of 'for preservation of one's own health', 20.7% of 'without side-effect'. Especially, the highest preference in preservation of one's own health showed in female, small and medium sized city dweller, medical insured, high socio-economic class, under thirties and fifties, over the college graduates, unmarried, simple labourer and technical expert. 3. In regard to patient's satisfaction toward Oriental medical care. 53.2% among respondents answered as satisfactory, 39.6% as a moderate, 7.2% as a unsatisfactory. Especially male, the person over 60 years old, high school graduates, sales-service man, married person and big city dweller expressed the more satisfactory toward outcome of Oriental medical care than the other person who was not. 4. Total scores(5.43±2.52) of the recognition level of basic knowledge about Oriental medicine was relatively low level, while appeared as th higher score in person in female, college graduates, administrators, dweller in Eup and Myoun. low socio-economic class. The main sources of basic information about Oriental medicine were mass media such as TV and radio (59.2%). 5. The contributing factors to use of Oriental medical care were level of age, satisfaction toward treatment, coping attitude as taking Oriental medicine whenever being unhealthy, marital state, educational level and one's own occupation. Especially, the use of Oriental medicine showed the positive correlation to level of age, religion. while the negative correlation to educational level and one's own health status. On the basis of these results, it suggested that the person's expectation toward oriental medical care is higher gradually, but basic knowledge information on Oriental medicine was relatively low level. Therefore, the author recommended that the development of educational program on Oriental medicine and policy making for should be needed cover wide area and the authorities and social groups of oriental medical care should consider the improvement of oriental medical care policies such as modernization of skills, standardization of hers medicine, lower cost of treatment.

의원성 사고로 발생한 타액선염 : 증례보고

김현우,허경회,이원진,허민석,이삼선,최순철 대한구강악안면방사선학회 2004 Imaging Science in Dentistry Vol.34 No.2

A case of sialadenitis is presented in a patient with painful swelling of the right mouth floor. The condition was caused by trauma on the right mouth floor during dental treatment, which had happened 15 days before admission. On aspiration, mucous secretion was found and ultrasonography showed obstruction of duct. Histopathological studies and surgical investigation established a definite diagnosis of obstructive sialadenitis caused by ductal laceration. As surgical treatment sialodochoplasty was selected. The case and relevant considerations are discussed.

일부지역 중·고등학생들의 흡연실태 조사연구

신옥순,남철현,김복용,최연희,박선희,박경옥,구재희 慶山大學校 保健福祉硏究所 2002 保健福祉硏究 Vol.7 No.-

This study was conducted to examine aspects of middle and high school students' drinking and smoking with analysis of related factors. The subjects of this study was 540 students in Kyungbuk Province. Data were collected from July, 2002 to September, 2002. The results of this study can be summarized as follows. 1. 43.6% of the boy students experienced smoking, while 12.2% of the girl students experienced it. 5.3% of the students at academy schools experienced smoking, while 44.7% of the students at vocational schools experienced it. 11.4% of the middle school students experienced smoking, while 33.9% of the high school students experienced it. 15.5% of them who lived in towns or villages experienced smoking and 38.3% of them who lived in small or medium sized cities experienced it.37.5% of the students who belonged to the lower economic class experienced smoking and 20.7% of the students who belonged to the upper economic class experienced it. 24.0% of the students who belonged to the middle economic class experienced it. It appears that the respondents showed significantly different smoking experience rates by gender, school types, grades, the number of family members, residences, and economic classes. 2. 14.5% of the respondents who lived with grandparents and parents experienced smoking and 26.5% of them who lived with parents experienced it. The smoking rate was significantly high in the groups of having one-parent, being unsatisfied with family life, making poor grades in studies, and having the father or the mother working as a salesperson. 3. 45.3% of the respondents who were unsatisfied with family life experienced smoking. The smoking rate of the respondents who were unsatisfied with it was significantly higher than that of the other groups. On the other hand, the smoking rates were not significantly different by daily life, schoolmate relation, health condition, and feeling stress. 4. According to smoking rate by frequency of drinking, 16.4% of the respondents who drank less than once a month smoked and 54.8% of them who drank more than twice a month smoked. The more frequently they drank, the higher their smoking rate was. Those who did exercise displayed significantly higher smoking rate than those who did not do exercise. Among the rates of the respondents' agonies, family disharmony was 50.5% and love problem was 39.2%. Economic condition preblem was 34.6%. It appeared that smoking was most influenced by the family disharmony. 5. The factors significantly influencing smoking experience were gender, school grade, schoolmate relation, score in studies, and exercise. From above results, it can be concluded that the students' smoking is a serious problems which can be resolved by simple approaches because it is interrelated complicatedly with gender, grade, family, school, etc. Schools, related organizations, and the government must closely work together to maximize the effectiveness of policy implementation concerning the smoking and drinking problem of the middle and high school students.

30% Minocycline 국소 약물송달제제의 생체내, 외방출역학, 세포독성 및 세포활성도 측정

최현순,이상철,김강주,장원규,정서영,정종평 대한구강생물학회 1992 International Journal of Oral Biology Vol.16 No.1

Present study was performed to examine in vitro and in vivo release kinetics, cell cytotoxicity and cellular growth survival of local 30% Minocycline delivery. The purpose of this study was to determine the possibility of clinical use of 30% Minocycline load polycaprolactone film(Mino-Strip). The size of Mino-strip is 6.5㎜×2.5㎜×0.3㎜, Mwt: 5.7㎎). In vitro releasing test, each film showed a large initial burst effect within first one and two hours and more than 84% of Minocycline was releasing test, each film showed a large burst effect within first two and three hours. A steady state kinetics was observed for 8 days both in vivo and in vitro releasing test. In cytotoxicity test, there was no significant cytotoxic effect in Mino-strip to human gingival fibroblast. In cellular growth survival test, there was no significant cellular growth survival effect in Mino-strip to human gingival fibroblast.

SM 45C강과 SS 41강의 미세조직과 파괴인성

최기순,김현철,임병수 成均館大學校 科學技術硏究所 1997 論文集 Vol.48 No.1

The effect of microstructure on fracture toughness of SM 45C steel and SS 41 steel has been investigated. Values of fracture toughness were measured in, each specimen of different microstructure and the investigation was carried out to find out the relationship between fracture toughness and microstructure. Fracture toughness increases with increasing grain size and spacing of the second phase(Fe_3C) particles in SM 45C. Strength ratio and toughness increased with increasing grain size and spacing of the second phase(Fe_3C) particles in SS 41 steel.

Mycobacterium fortuitum-chelonei complex 균체항원의 민감성과 특이성

이현우,최철순,정상인,양용태 중앙대학교 의과대학 의과학연구소 1985 中央醫大誌 Vol.10 No.1

Antigenic preparations were made from seven strains of Mycobacterium fortuitum-chelonei complex(MFCC) extracted with phosphate buffered saline(PBS extracts), with 10%, trichloroacetic acid solution (TCA extracts) and with veronal buffered saline solution containing 0.1% Triton X-100(Triton extracts). Serologic reactivities of the antigenic preparations were assayed for immune precipitation by Ouchterlony double diffusion in-gel technique against antisera of rabbits immunized with M. fortuitum TMC 1529 and M. chelonei TMC 1544. Antigenic relationships between Triton extracts of M. fortuitum and M. chelonei were analyzed by two-dimensional immunoelectrophoresis(2D-IE) and fused rocket immunoelectrophoresis(FRIE). The results obtained are summarized as follows: 1. Of antigenic preparations of PBS extracts, TCA extracts and Triton extracts, the Triton extracts and the PBS extracts proved to be active for immune precipitation, but the TCA extracts was inactive. The precipitation reaction of Triton extracts was more sensitive than PBS extracts, and the precipitation reaction of Triton extracts was enhanced by disintegration of cells with sonification, but the cross reaction was also increased. 2.' The Triton extracts of 5 strains of M. fortuitum exhibited 9 common precipitinogens with reference serum against TMC 1529 and one common precipitinogen with reference serum against TMC 1544. but the antigens of TMC 1544 with or without disintegration of cells gave a specific precipitinogen with reference serum against TMC 1544 in addition to a common precipitinogen. 3. Although the electrophoretic patterns of Triton extracts obtained from different strains and species were not demonstrated, 7 strains of the MFCC could be divided into four groups by the relative electrophoretic mobilities(REM) of the antigens with respect to bovine serum albumin(REM value); group Ⅰ(REM =0.18) 2 strains, group Ⅱ(REM = 0.27) 2 strains, group Ⅲ (REM = 0.38) 2 strains and group Ⅳ(REM = 0.49) 1 strain, but the existence of any significant relationship between the REM value and species was not recognized. 4. By means of FRIE, the presence of 3 to 5 common precipitinogens and 1 to 2 species-specific precipitinogens were observed in the Triton extracts of M. fortuitum and M. chelonei. 5. By the use of the reference antisera with a titre of at least 1 : 80 against M. fortuitum TMC 1529 and M. chelonei TMC 1544, the strains of M. fortuitum and M. chelonei could be differentiated by FRIE. In conclusion, this study established that the Triton extracts of the MFCC proved to be active for immune precipitation and contained species-specific procipitinogens, and reproducible amounts of such an antigen for immunodiffusion test could be easily prepared with one plate of heavy cultures.

Boxing 競技中의 Energy消費量과 運動强度에 關한 硏究

趙顯喆,宋淳天,鄭正眞 龍仁大學校 1989 용인대학교 논문집 Vol.5 No.-

The purpose of this study is to analyse energy cost by HR-VO2 regression equation and exercise intensity by %HRmax.during the boxing game.The subject were six elite boxing players and five ordinary boxing players. The results obtained from the above research can be summarized follows. 1.Mean energy cost of elite boxing players and ordinary boxing players during the boxing game were 13.54, 11.32㎉/min in 1round, 15.12, 12.86㎉/min in 2round and 15, 50,13.06㎉/min in 3round, respectively. 2.Total energy cost of elite boxing players and ordinary boxing players during the boxing game were 159.84㎉/11min and 136.40㎉/11min, respectively. 3.The exercise intensity of elite boxing players and ordinary boxing players during the boxing game was 93.1, 88.4 %HRmax.in 1round, 97.9, 95.6 %HRmax.in 2round and 97.9, 95.8%HRmax.in 3round, respectively. 4.To perform the boxing game effectively, players will have to elevate their cardio respiratory performance.

상악동의 점막비후에 대한 WATERS방사선사진과 파노라마방사선사진 및 전산화단층사진의 진단능 비교

최순철,이삼선,현영민 大韓口腔顎顔面 放射線學會 1998 Imaging Science in Dentistry Vol.28 No.1

With the CT findings as gold standard, the sensitivity, the specificity, and the diagnostic accuracy of Water's radiography and Waters' radiography with panoramic radiography were compared in the diagnoses of antral mucosal thickening of 16 patients. Three oral radiologists and three non-oral radiologists interpreted the Waters' radiographs and after 4 weeks, interpreted the Waters' radiographs and panoramic radiographs simultaneously. The interpretation point was the existence or the non-existence of the mucosal thickening on the medial, the posterolateral, the floor, and the roof of maxillary sinus. The obtained results were as followed: 1. In oral radiologist group, the sensitivity, specificity and diagnostic accuracy of Waters' film were 0.7250, 0.8489 and 0.7578 respectively. 2. The sensitivity and the diagnostic accuracy in oral radiologist group were higher than those of non-oral radiologist group (P<0.05), but there was no significant difference between two groups in the specificity (P>0.05). 3. There was no significant difference of the diagnostic abilities except the specificity in oral radiologist group between Waters' radiography and Waters' radiography with panoramic radiography (P>0.05). 4. The sensitivity and the diagnostic accuracy were the highest in the case of medial wall interpretation, the specificity was the highest in the posterolateral wall. 5. In the posterolateral wall and the floor, the sensitivity and the diagnostic accuracy of oral radiologist group were higher than those of non-oral radiologist group (P<0.05).

몇가지 β-lactam 항생제의 약효평가를 위한 Minimum Inhibitory Concentration(MIC)의 비교

洪淳德,金鐘國,李東善,河相哲,李相瀚,李載蘭,安賢淑 慶北大學校 1991 論文集 Vol.51 No.-

In order to screen the new β-lactam antibiotics for clinical use. we were compared MIC values of various β-lactam antibiotics. We also tested the influence of pH, inoculum size, stability of antibiotics in medium and some kinds of media on MIC value. As a result, cefotaxime, cefoperazone, piperacillin, cefamandole, cephaloridine, cephapirin, cefazolin, cephalothin, cephaioylycn were scored in antimicrobial activity of MIC data.