Gender-related Differences in Management of Nonvalvular Atrial Fibrillation in an Asian Population

Lee, Jung Myung,Kim, Tae-Hoon,Cha, Myung-Jin,Park, Junbeom,Park, Jin-Kyu,Kang, Ki-Woon,Shim, Jaemin,Uhm, Jae-Sun,Kim, Jun,Park, Hyung Wook,Lee, Young Soo,Choi, Eue-Keun,Kim, Chang-Soo,Joung, Boyoung,K The Korean Society of Cardiology 2018 Korean Circulation Journal Vol.48 No.6

<P><B>Background and Objectives</B></P><P>Gender-related differences in health care utilization for atrial fibrillation (AF) are increasingly recognized. However, large cohort data for examining gender-related differences in AF are lacking in Asian populations.</P><P><B>Methods</B></P><P>The Registry for Comparison Study of Drugs for Symptom Control and Complication Prevention of AF (CODE-AF Registry) is a prospective observational cohort-study that enrolled participants at 10 tertiary hospitals in South Korea. Baseline characteristics retrieved from the CODE-AF Registry were analyzed.</P><P><B>Results</B></P><P>A total of 6,274 patients were recruited (mean age 67±11 years, mean CHA<SUB>2</SUB>DS<SUB>2</SUB>-VASc score 2.7±1.7, 63% male, 65% paroxysmal AF) from June 2016 to April 2017. Women underwent less electric cardioversion (12.3% vs. 19.6%, p<0.001), less radiofrequency ablation (12.4% vs. 17.9%, p<0.001), and less antiarrhythmic drug therapy (44.7% vs. 49.5%, p<0.001), despite having more severe symptoms (symptom class III or IV, 45.8% vs. 37.5%, p<0.001). Among patients with a CHA<SUB>2</SUB>DS<SUB>2</SUB>-VA score of 2 or more, a slightly higher proportion of women were taking oral anticoagulants than men (85.7% vs. 81.9%, p=0.002), and non-vitamin K antagonist oral anticoagulant (NOAC) use was more prevalent in women than men (70.4% vs. 62.3%, p<0.001). Insufficient NOAC dosing was very common, more so in women than men (61.5% vs. 56.3%, p<0.001).</P><P><B>Conclusions</B></P><P>Female patients with AF were treated more conservatively and rhythm control strategies were used less frequently than in males, even though the female patients with AF had more severe symptoms. While insufficient NOAC dosing was common in both sex, it was significantly more frequent in women.</P>

당뇨병 환자에서 혈장 Thrombin-Antithrombin Ⅲ 및 Plasmin-α_2-Plasmin Inhibitor 복합체의 임상적 의의

김경욱,김은숙,정상수,윤수지,박우일,이준희,남수연,안철우,문병수,김경래,차봉수,송영득,임승길,이현철,허갑범 대한당뇨병학회 2002 Diabetes and Metabolism Journal Vol.25 No.5

연구배경:당뇨병 환자에서 혈액응고 및 섬유소용해 체계의 이상경향이 있어 그 결과로 여러 혈관합병증의 발생위험이 높다는 사실은 널리 알려져 있다. 그 기전은 아직 확실히 밝혀지지 않았으나, 고혈당으로 인한 혈장 단백질들의 비효소성 당화작용이나 산화성 스트레스로 인한 유리 라티칼 작용으로 응고항진이나 섬유소용해 활성의 저하를 유발하는 것으로 생각되고 있다. 최근 응고 및 용해인자와 그 억제자의 복합체들의 증가가 이 상태를 비교적 예민하게 반영한다고 알려져 있다. 방법:본 연구에서는 당뇨병 환자 101명과 정상 대조군 20명에서 혈장내 thrombin­antithrombin complex(TAT)와 plasmin­α₂­plasmin inhibitor complex(PIC)를 측정하여 비교하고, 당뇨병 환자에서 미세혈관 합병증과 대혈관합병증의 유무에 따른 차이와, 이미 혈관 질환의 위험인자로 알려져 있는 인자들간의 상관성을 알아보고자 하였다. 결과:1. 환자의 분포를 살펴보면 혈관합병증이 있는 군은 85명, 혈관합병증이 없는 군은 16명이었고, 평균연령은 각각 57.9±14.1세, 49.9±16.6세로 혈관 합병증이 있는 군에서 더 나이가 많았고, 체질량지수는 23.2±3.4㎏/㎡, 24.1±3.4㎏/㎡로 두 군간 유의한 차이는 없었다. 또 두 군간의 혈압 및 HbA1c, 공복혈당 및 인슐린과 C­peptide, 총 콜레스테롤, 중성지방, HDL­콜레스테롤, Lp⒜는 유의한 차이가 없었고, 미세혈관합병증이 있는 군에서 당뇨병의 유병기간이 길었다. 2. TAT 및 PIC의 농도는 정상 대조군에서는 2.8±1.2 ng/mL, 240.4±69.7 ng/mL이었고, 당뇨병 환자군에서는 9.5±22.6 ng/mL, 472.2±258.7 ng/mL이었다. TAT와 PIC 모두 당뇨병 환자군에서 정상 대조군에 비해 유의하게 증가되어 있었고(p<0.001), TAT/PIC ratio는 두 군간 차이가 없었다. 3. 당뇨병 환자의 혈관합병증에 따른 TAT 및 PIC, fibrinogen 농도는 합병증이 없는 군은 각각 4.1±2.4ng/mL, 362.2±272.0ng/mL, 322.7±102.4mg/mL으로 PIC와 fibrinogen의 증가를 보였으나, 연령을 보정한 후에는 통계학적 유의성은 없었다. 또 대혈관 합병증군에서는 각각 6.0±4.9 ng/mL, 507.4±321.6 ng/mL, 427.1±194.7 mg/dL이었으며 미세·대혈관 합병증군에서는 10.4±6.4 ng/mL, 484.8±269.7 ng/mL, 388.4±132.4 mg/dL으로 TAT의 증가를 보였으나 역시 연령을 보정한 후에는 통계학적 유의성은 없었다. 4. 미세혈관합병증군에서 HbA1c(>8%)가 높은 군의 PIC 농도가 유의하게 높았고(p=0.049), 대혈관합병증군에서 HbA1c(>8%)가 높은 군의 총 콜레스테롤 농도가 유의하게 높았다(p=0.042). 5. 총 당뇨병 환자군에서 PIC는 fibrinogen과 HbA1c와 양의 상관관계를, BMI와 음의 상관관계를 보였으며(r=0.47, 0.31,-0.25), 혈관 합병증이 없는 당뇨병 환자군에서만 TAT는 HbA1c와 양의 상관관계를 보였다(r=0.67). 결론:이상의 결과에서 혈장 TAT 및 PIC 농도는 당뇨병 환자에서 정상 대조군에 비해 의미있게 증가되어 있었고, 당뇨병 환자군에서는 연령의 증가와 유병기간이 혈액응고항진 및 용해의 장애에 큰 역할을 함을 알 수 있었으며, 총 당뇨병 환자군에 PIC와 HbA1c와 양의 상관관계를, BMI와 음의 상관관계를 보였으며 혈관 합병증이 없는 당뇨병 환자군에서만 TAT는 HbA1c와 양의 상관관계를 보였다. 따라서 당뇨병 환자에서 혈액응고 및 용해의 장애가 동반되어 있다고 볼 수 있으며, 혈장 TAT 및 PIC는 혈관합병증으로의 진행을 예측하는 지표로서 유용하리라 생각된다. 또 혈당조절정도와 상관성이 있으므로 혈당조절후에 추적검사를 시행하여 합병증의 예방이 가능한지 추후 연구가 필요하리라 생각된다. Background : Abnormality of coagulation and fibrinolystic system is known as a predisposing factor of vascular complication in diabetes. Although the pathogenesis is not well known, non-enzymatic glycation reaction and the increase in production of free radicals due to an increased oxidative stress may be linked to the hypercoagulibility and hypofibrinolytic activity. As indices of abnormality in coagulation and firinolysis in peripheral blood, plasma thrombin-antithrombin Ⅲ complex (TAT) and plasmin-α_2-plasmin inhibitor complex (PIC) were measured. The purpose of this study was to clarify whether hypercoagulability exists in diabetic patients with or without vascular complication. Methods : In our study, we measured plasma thrombin-antithrombin Ⅲ compelx (TAT) and plasmin-α_2-plasmin inhibit or complex (PIC) in 101 diabetic subjects and 20 controls. Comparing TAT and PIC levels in diabetic microvascular complication group, diabetic macrovascular complication group and controls, we examined correlation between risk factors associated with diabetic vascular complication. Results : 1. The group with diabetic vascular complication was older than group without complication. There was no significant difference in BMI, blood pressure, HbA_ic, blood sugar level, insulin, C-peptide, serum creatinine, total cholesterol, triglyceride, HDL-cholesterol, Lp (a) between two groups. The group with diabetic microvascular complication had longer duration of diabetes. 2. Concentration of TAT and PIC were 2.8±1.2 ng/ mL, 240.4±69.7 ng/ mL in controls and 9.5±22.6 ng/ mL, 472.2±258.7 ng/ mL in diabetic patients, respectively. TAT and PIC were significantly higher in diabetic patients than in control (p<0.001). But TAT/PIC ratio was no significant difference between two groups. 3. In diabetic patients, concentration of TAT and PIC and fibrinogen were respectively 4.1±2.4 ng/ mL, 362.2±272.0 ng/ mL, 322.7±102.4 mg/ dL in group without vascular complication and 5.3±4.1 ng/ mL, 529.5±258.7 ng/ mL, 374.9±106.2 mg/ dL in group with microvascular complication, which group had increase in PIC and Fibrinogen but no significance after correction of age. Concentration of TAT and PIC and Fibrinogen were 60.±4.9 ng/ mL, 507.4±321.6 ng/ mL, 427.1±194.7 mg/ dL in macrovascular complication, and 10.4±6.7 mg/ mL, 484.8±269.7 ng/ mL, 388.4±132.4 mg/ dL in combined vascular complication which group showed increase of TAT but also had no significant increase after correction of age. 4. In diabetic microvascular complication patients, group of high HbA_1c (>8%) (p=0.049) had significant high PIC concentration. In diabetic macrovascular complication patients, group of high HbA_1c (>8%) (p=0.042) had significant high total cholesterol concentration. 5. In all diabetic patients, PIC was positively correlated with fibrinogen and HbA_1c and negatively correlated BMI (r=0.47, 0.31, -0.25). Only in daibetic patients without angiopathy, TAT was positively correlated with HbA_1c (r=0.67). Conclusion : In this study, plasma TAT and PIC concentration significantly increased in diabetic patients compared with controls, and PIC was increased in group with microvascular complication, TAT were increased in group with combined micro macrovascular complication. However, there was no significance relationship existed when correctinf for age. PIC was correlated with HbA_1c. TAT was correlated with HbA_1c only in the group without angiopathy. Abnormality of coagulation and fibrinolysis were combined in diabetes, plasma TAT and PIC can be used as an index of vascular complication. Also we found the correlation with the degree of the blood glucose control. Therefore we need follow up study for the possibility of prevention of vascular complication after controlling the blood glucose to age-matched patients (J Kor Diaabetes Asso 25:354~363, 2001).

품행장애 청소년을 위한 외래집단정신치료 치료요인

이후경,김선재,차정화,봉수연,안현주 대한신경정신의학회 2000 신경정신의학 Vol.39 No.2

연구목적: 집단정신치료는 또래집단을 중요시하는 품행장애 청소년의 치료로서 매우 효과적인 것으로 알려져 있으나 한국에서는 아직 활성화되지 못하고 있다. 이에 따라 저자들은 품행장애 청소년에게 효과적으로 적용될 수 있는 폐쇄형, 동질적인, 시간제한(10회), 외래집단정신치료를 주 1회 실시하였다. 본 연구의 목적은 ①품행장애 청소년을 대상으로 집단정신치료를 시행하여 효과성을 평가하고, ②치료요인을 조사하여, ③ 집단정신치료를 품행장애 청소년에게 효과적이면서 효율적으로 적용될 수 있는 치료방법으로 정착시키는 데 있다. 대상 및방법: 본 연구는 1998년 10월붜 12월까지, 1999년 4월부터 6월까지 두차례에 걸쳐 실시하였다. 대상군은 품행장애 범주에 해당하는 H고교 2학년 여학생 총 18명(4명 도중 탈락), 대조군은 같은 범주에 해당하는 H고교 2학년 여학생 중 치료에 참여하지 않은 총 18명(4명 도중 탈락)이었다. 평가도구로는 프로그램 실시 전후에 자기보고식 비행척도, 공격성척도, 충동성척도을 시행하였고, 매 회기가 끝난 직후 Yalom의 13가지 치료요인척도, 집단치료 만족도 설문지를 시행하였으며, 종결모임시 총평가 설문지를 시행하였다. 결과: 치료요인의 변화를 집단발단단계에 따라 전후반기로 나누어 비교하였을 때, 전반기(1∼5회)에 상위를 차지한 치료요인은 순서대로 실존적인자, 보편성, 카타르시스, 리더와의 동일시, 구성원과의 동일시이었으며, 후반기(6∼10회)에 상위를 차지한 치료요인은 카타르시스, 실존적인자, 리더와의 동일시, 구성원과의 동일시, 구성원의 조언이었다. 전반기에 비해 후반기에 상대적으로 카타르시스, 구성원의 조언이 상승하였고 보편성은 하락하였다. 이타주의와 일차가족집단의 교정적 반복발달은 전후반기 모두 최하위를 기록하였다. 집단치료 만족도 설문에서 전반기는 45.7%, 후반기에는 83.3%가 도움받는 것으로 나타났고, 총평가 설문에서 85.7%가 기회가 있다면 다음에도 참여하고 싶다고 보고하였다. 결론: 시간제한 외래집단정신치료가 품행장애 청소년 에게 적용할 때 매우 효과적이면서도 만족도가 높은 것으로 나타났다. 청소년을 대상으로 외래집단정신치료를 시행하는 것은 구성상의 어려움, 동기부족, 기금부족 등, 여러 제반 문제가 있으나 확대 시행되어야 할 것으로 생각된다. Objectives: Group psychotherapy is known to be an dffective treatment program for adolescents who attach importance to peer relationship, but it is not activated in Korea. Therefore, researchers performed weekly the closed, homogeneous, time-limited(10 sessions), outpatient group psychotherapy for adolescents with conduct disorder. Objectives of this study were as follows ; first, we practiced the group psychotherapy for adolescents with conduct disorder and evaluated its effectiveness ; second, we examined the therapeutic factors which were used by participants ; third, we intended to settlee down the group psychotherapy for adolescents with CD as an effective and efficient treatment modality. Methods: This study was performed two times from October to December in 1998 and from April to June in 1999. It was sponsored by Youth Counselling Center in H city. The case group were composed of 15 female students who were second grade in H high school, and 4 students were dropped out. The control group were composed of 18 female students who were same grade in H high school and 3 students were dropped out. Before and after this program, self-report delinquency scale, aggression scale and impulsivity scale were asked to them. And just after each session, Yalom 13 therapeutic factors scale and satisfaction questionnaire for group psychotherapy were asked to them. And at last meeting, total assessment questionnaire was asked to them. Results: We compared the change of therapeutic factors between the former half sessions (1-5) and the later half session(6-10), and the results were as follows ; in the former half, the upper ranks of therapeutic factors were existential factor, universality, catharsis, identi- fication with leader, and identification with members in order. And in the later half, the upper ranks of therapeutic factors were catharsis, existential factor, identification with leader, identi - fication with members, and guidance of members in order. The rank of catharsis and guidance of members went upward and the rank of universality went downward when we compared the ranks in the former half to those in the later half. Altruism and family enactment were the lowest ranked in both half. The satisfaction questionnair for group psychotherapy showed to be helped by participants at the rate of 45.7% in former half, 83.3% in later half. The total assessment questionnaire showed the willingness of re-participation at the rate of 85.7% if future opportunity of group psychotherapy is given for them. Conclusions: The time-limited group psychotherapy for adolescents diagnosed by conduct disorder was very effectively practiced and the participants reported high level of the satisfaction. The outpatient group psychotherapy for adolescents would be expanded and practiced though there are several accompanied problems including the difficulty of structuring, the deficit of motivation, and financial problem.

고농후사료에 대한 목탄 및 활성탄의 첨가 수준이 인공위내 소화율, 휘발성 지방산 및 개스 생산량에 미치는 영향

이수기,차상우,김선균 충남대학교 농업과학연구소 2002 농업과학연구 Vol.29 No.2

본 시험은 목탄 및 활성탄의 첨가가 사료의 반추위내 pH·발효성상·건물 및 영양소 소실율·가스 생산량에 미치는 영향을 조사하기 위하여 in vitro 조건에서 실시되었다. 활성탄과 목탄의 첨가수준은 0.50% 및 1.0%의 수준이었으며, 사료의 조농비율은 오차드 건초와 농후사료 비율은 2:8로 하였다. 그리고 처리간 유의성은 5% 수준에서 검정하였다. 시험 결과를 요약하면, 위액의 pH는 활성탄의 첨가로 유의하게 높아졌다. 그리고 암모니아태 질소는 활성탄 첨가에 의하여 유의하게 높아졌으며, 목탄첨가구는 모첨가구와 비교할 때 유의한 차이가 인정되지 않았다. 또한 VFA molar ratio에서는 전구간에 유의한 차이가 인정되지 않았으며, C2/C3 비율은 유의한 차이는 아니지만 활성탄구가 다소 낮아지는 경향을 나타내었다. 그러나 목탄첨가구에서는 대조구와 유의한 차이가 인정되지 않았다. 건물·조단백질·조지방·NDF·ADF 및 hemicellulose의 소실율은 활성탄 첨가에 의하여 유의하게 증가되는 경향을 나타냈다. 목탄첨가구에 있어서는 0.5%구보다는 1.0%구가 유의하게 높은 성적을 나타내었다. 그러나 hemicellulose의 소실율은 전구간에 유의한 차이가 없었다. 가스 생산량에 미치는 영향은 활성탄 및 목탄 첨가구가 대조구에 비하여 유의하게 많은 양을 나타내었으며, 활성탄 첨가구와 목탄 첨가구를 비교하면 유의한 차이는 아니지만 활성탄 첨가구가 높은 경향을 나타내었다. 위 결과에서 보듯이 활성탄은 가축의 생산성 향상에 유리한 조건을 제공하는 경향이 있지만, 이것을 좀 더 명확히 밝히기 위해서는 활성탄의 흡착능력·위내의 세균층에 대한 연구 및 많은 생체실험도 병행되어야 할 것으로 생각된다. This study was conducted to investigate the effects of the addition of activated charcoal (AC) and oak charcoal on in vitro ruminal fermentation characteristics, nutrient disappearance, and ruminal gas production. AC and oak charcoal were added at the levels of 0.50, and 1.00 % to experimental diet (roughage/concentrate ratio ; 2/8). Ruminal pH and ammonia-N tended to increase by adding AC(P<0.05). But oak charcoal did not affect the ruminal pH and ammonia-N. Although not significant, ruminal total VFA and molar percentage of butyric acid tended to decrease in AC diets, but molar percentage of acetate and propionate were not affected by adding AC. Ruminal degradation of dry matter, crude protein NDF, and ADF in AC diets tended to increase than in non-AC diet, however, no tendency in ruminal degradation of hemicellulose was observed. Ruminal gas production tended to increase in the AC and oak charcoal diets(P<0.05). Although there appeared some beneficial effects in adding AC to ruminant diets in this study, more works should be done with AC before we can make clear conclusion on the use of AC in the ruminant diets.

활성탄 및 목탄의 첨가가 산양의 영양소 이용율 및 반추위내 발효성상에 미치는 영향

차상우,이수기 충남대학교 농업과학연구소 2005 농업과학연구 Vol.32 No.2

This study was conducted to investigate the effects of the addition of activated charcoal (AC) and oak charcoal on the ruminal fermentation characteristics, nutrient utilization in Korean native goats. Compared to reference diet, digestibility of dry matter, and crude protein in AC and charcoal diets tended to incraese. However, any tendency in ruminal degradation of crude fat was not observed. Ruminal degradation of NDF in AC diets tended to be more increased than that in non-AC diet. Although it was not significant, ADF tended to be increased in AC and charcoal diets. AC and charcoal did not affect the ruminal pH and ammonia-N. Concentration of total VFA and butyrate tended to be increased by adding AC and charcoal(p<0.05). Although it was not significant, acetate/propionate ratio tended to decreased in AC and charcoal diets. Although there appeared some beneficial effects in adding AC and charcoal to ruminant diets in this study, more works could be needed with AC before we can make clear conclusion on use of AC and charcoal in the ruminant diets.

불소함유 지문방지제 합성

차미선,범정철,하종욱,박인준,소원욱,이수복 한국공업화학회 2004 응용화학 Vol.8 No.2

The anti-fingerprint coating agents, consist of a fluorinated macromer(F-macromer) were prepared by marcromonomer technique and hydrosilation reaction. The products were characterized by ¹H-NMR, differential scanning calorimetry. The surface properties of the anti-fingerprint coating agents were investigated by the contact and sliding angle measurement. The modified surface with the anti-fingerprint coating agents showed the extremely low surface free energy of a 10.09 dyn/cm and the sliding angle was smaller than that of commercial products. That is, The synthesised coating agents can be the good candidate for the water and oil repellent, soil release and anti -fingerprint application coating agent.

음성분석에 입각한 자동코드화 방식의 신경외과계 환자관리 시스템

차은종,김영규,이태수,채수일,김동호,이무섭 충복대학교 의과대학 충북대학교 의학연구소 1994 忠北醫大學術誌 Vol.4 No.1

신경외과계 입원환자의 퇴원요약기록을 전산관리하는 시스템을 개발하였다. 주기억장치 4MB와 보조기억장치 120MB HDD를 장착한 PC-386DX시스템을 기반으로 개발하였고 소프트웨어로는 FoxPro V2.0을 사용하였다. 퇴원 요약기록의 관리시 중요한 항목인 진단명은 통상 사용하는 진단명 그 자체를 입력한 후 해당코드를 자동으로 색출해내는 자동코드화 방식을 사용하였다. 그러나 오류 코드가 발생하기 쉬운 패턴분류 방식을 지양하고 입력오류 발생시 입력진단명을 음성분석하여 음원이 동일한 유사코드를 찾는 음성분석 방식을 취하였다. 두개이상의 유사코드중 사용자가 정확한 코드를 선택하도록 하여 오류코드를 방지하였다. 논리연산조건식을 사용한 검색을 실현함으로써 다양하고 융통성있는 검색기능을 보장하였고 편리한 자료관리 방식이 가능하여 비전문가라 할지라도 손쉽고 편리하게 사용할 수 있었다. 신경외과계 입원환자를 대상으로 사용한 결과 그 실용성을 입증할 수 있었다. A discharge summary data management system was developed for neurosurgical patients. The system, written in FoxPro V2.0, ran on a PC-386DX system equipped with 4MB main memory and 120MB HDD. Automated coding was implemented by comparing the input diagnosis onto the description of the possible code list. However, any alphabet pattern classification techniques were prevented, instead sound analysis was performed on each word of the input diagnosis using the internal sound function of FoxPro software. On an input typing error, the diagnosis codes of similar sound characteristics were presented on screen so that the user selects the accurate diagnosis. This eliminated coding error inevitable for any pattern classification techniques. Data search function of the present system was very powerful and flexible, since the system performs the data search based on the user defined logical equation. In addition, the database management was easy for any inexperienced users to apply, minimizing accidental data loss. The system was tested in the neurosurgery ward and evaluated to be practical and useful.

AMDF를 이용한 화자위치 추정에 관한 연구

차경환,박수홍,송도훈,이채봉 東西大學校 1999 동서논문집 Vol.5 No.-

본 연구에서는 원격 화상회의 시스템 등에서 Camera를 자동적으로 제어하기 위해 화자의 음성신호를 4개의 마이크폰 배열(Microphone Array)로 수음하여 그 신호에 의해 화자의 위치를 추정한다. 마이크로폰으로 수음한 음성신호의 TDE(Time Delay Estimation)를 계산할때 그 연산량을 감소시키기 위해 AMDF알고리즘을 사용한다. 각 마이크로폰 출력신호에 대해 amdf 알고리즘으로 시가니연을 구하고 DOA(Direction of Arrival)를 계산한다. 다양한 조건하에서 음성신호로 실험한 결과, AMDF 알고리즘을 이용한 화자위치 추정의 정확도가 기존의 cross-correlation 방법에 비해서 우수한 성능을 나타내었다. This paper decribes the estimation of speech source using four microphones array singnal for the automatic control caramera position in the teleconference system. To reduce the calculation rate, AMDF algorithm is empoloyed for the TDE(Time delay Estimation) of the speech signal with microphone. The time delay is calculated using AMDF algorithm of each microphone output signal and DOA is obatained. According to the estimation of speech source in speech signal/아/under various conditions. AMDF-technique-based method yields superier performance to the one with cross-correlation method.

국내벤쳐기업의 성과영향요인에 관한 연구

차수련,이정수 동국대학교 경제경영연구원 1998 經濟經營硏究 Vol.22 No.1

The purpose of this study is to identify the influencing factor of venture business performance in Korea. For this purpose the previous study was reviewed and empirically examined the relationship between influencing factors and venture business performance. In this study, the data are collected from the number of 97 venture busineses that received assistance from the venture capital on the basis of a cluster sampling method. Influencing factors are selected as follows; internal locus of entrepreneur, marketing experience of entrepreneur, product innovativeness, process innovativeness, marketing assistance and technical assistance. As analyses methodology, simple regression analyses and reliability test are employed. The major findings of this study are as follows; Firstly, The higher the degree of internal locus of control of entrepreneur, The better venture business performance. But marketing experience of entrepreneur not significantly correlated with venture business performance. Secondly, The higher the degree of product innovativeness and process innovativeness, The better venture business performance. Thirdly, Both of marketing assistance and techinical assistance not significantly correlated with venture business performance. These findings can contribute to decision-making of potential entrepreneur, policy maker, and venturecapitalist. those may have some implication for researcher. This study have several limitation such as operationalization of influencing factor, methodology of single model, and sampling method. Further research with adding influencing factors and random sampling will be needed to improve this study.

鋼의 酸洗廢液을 利用한 Mn-ferrite 磁性잉크 製造에 관한 연구

車東德,徐利洙,金營三 동아대학교 공과대학 부설 한국자원개발연구소 1990 硏究報告 Vol.14 No.2

This papper describes the results on formation of Mn-ferrite particles to be used in making magnetic ink from the picking liquor of steel which contain 8.9wt% of Fe ion (in which ㏖ ratio of Fe^(2+)/Fe^(3+)=1) and 1.5-5.0 ㏖ ratio of Fe/Mn^(2+) under conditions of pH 11, temperature of 80℃, air blowing rate of 100cc/sec. 1) Mn-ferrite particles at Fe/Mn^(2+) ㏖ ratio if 1.5-5.0 were of ultra fine sizes less than 180 angstrom. 2) It was possible to produce magnetic ink by coating the oleic and sodium dodecyl benzene sulfonate on the surface of the Mn-ferrite particles made from the waste pickling liquor of steel and dispersing them into water. 3) As the result of filtering from the picking liquor of steel, the residue concentrates of the filterate solution were conformed to be mainly of Cl, Cr^(3+), Cr^(6+), and Zn with their conncentrations of 2690, 0.021, 0.084 and 0.021 ppm respectively. Accorddingly, it may not be a problem as a foul water of urban.