여수국가산업단지 인근 지역 대기오염물질 농도에 영향을 미치는 요인분석

김민영,변정훈,이영훈,이건영,한지은,이예림,임지현,장봉기 순천향대학교 기초과학연구소 2022 순천향자연과학연구 논문집 Vol.28 No.1,2

Eight monitoring stations in the Yeosu National Industrial Complex will determine the concentration of air pollutants measured every hour in 2019, analyze what factors affect them, and how they correlate with the air pollutant measurements. Six air pollutants (SO2, NO2, O3, CO, PM-10 and PM-2.5) measured at eight monitoring stations around Yeosu National Industrial Complex (Seogang-dong, Wolnae-dong, Munsu-dong, Yeocheon-dong, Deokchung-dong, Hwayang-myeon, Yulchon-myeon, Samil-dong) the measurement data for each hour of the year were downloaded to analyze the concentration by weather condition, time zone, season, separation distance from Yeosu Industrial Complex, and separation distance from Gwangyang Industrial Complex. SO2, NO2, and CO concentrations were significantly higher in winter, significantly lower in summer, and O3, PM-10, and PM-2.5 concentrations were significantly higher in spring. SO2, CO, PM-10, and PM-2.5 concentrations were significantly higher between 10 a.m. and 12 p.m., NO2 concentrations were significantly higher between 7 a.m. and 9 a.m., and O3 concentrations were significantly higher between 13 p.m. and 15 p.m.(p<0.001). The concentration of air pollutants (SO2, NO2, CO, PM-10, PM-2.5) excluding O3 was found to have a negative (-) correlation with weather condition, and in the case of O3, it was found to have a positive (+) correlation with PM-10, PM-2.5, temperature and wind speed. It was confirmed that the concentration of air pollutants emitted from the Yeosu National Industrial Complex differs depending on the season, time and distance to the industrial complex. This study aims to establish measures to minimize health damage to residents living relatively close to the industrial complex and contribute to the establishment of management and response measures according to the properties of substances to reduce the concentration of air pollutants in the future.

Efficacy and Safety of Blood Stasis Based Herbal Medicine for Patients with Traffic Accident : A Prospective Observational Study

Bong, Sung Min,Jo, Hyo Rim,Jang, Woo Seok,Choi, Seong Kyeong,Sung, Won Suk,Jung, Chan Yung,Lee, Seung Deok,Kim, Kyung Ho,Kim, Eun Jung Korean AcupunctureMoxibustion Medicine Society 2020 대한침구의학회지 Vol.26 No.5

Background: Blood stasis (BS) is commonly used for pattern identification in traumatic injuries, including traffic accidents (TAs). Various studies have identified the efficacy of Korean medicine treatments for TA patients, but studies focusing on the BS-based herbal medicine (BSHM), including Tongdo-san (TDS), are rare. Methods: This was a single-center, prospective observational study, conducted from August 24^th, 2018 to December 27^th, 2018, which included 40 TA patients. Participants underwent routine Korean medicine treatments including acupuncture, electronic moxibustion, cupping, physical therapy, and herbal medicine. In the herbal medicine treatment, participants took BSHM with more than 3 days including taking TDS. The primary outcome measures were the scores from a 100 mm visual analogue scale (VAS) and numerical rating scale (NRS). Secondary outcome measures included scores from EuroQol-5 dimension (EQ-5D) and EQ-VAS questionnaires, the BS and cold/heat indices, and safety assessments. Results: There were significant improvements in the VAS, NRS, EQ-5D, EQ-VAS scores, and BS index after treatment. In the sub-analysis, VAS, NRS, EQ-5D, and EQ-VAS scores were higher in groups with a higher BS index. The moderate and severe BS index groups showed more improvement than the minor BS index group, and there was a significant difference in the EQ-5D scores. There was no significant differences observed in cold/heat index groups scores. Conclusion: BS is associated with TA-related symptoms. BSHM, including TDS, may significantly reduce BS, pain, and discomfort.

지하철 환승역의 공간이용행태와 공간구조 사례연구 - 신도림역과 사당역을 대상으로 -

지봉근(Ji, Bong-Geun),김채은(Kim, Chae-Eun),이예승(Lee, Ye-Seung),장석윤(Jang, Seok-Yoon),장세림(Jang, Se-Rim),김영욱(Kim, Young-Ook) 대한건축학회 2019 대한건축학회 학술발표대회 논문집 Vol.39 No.2

Lipoteichoic Acid Isolated from Lactobacillus plantarum Inhibits Melanogenesis in B16F10 Mouse Melanoma Cells

Kim, Hye Rim,Kim, Hangeun,Jung, Bong Jun,You, Ga Eun,Jang, Soojin,Chung, Dae Kyun Korean Society for Molecular and Cellular Biology 2015 Molecules and cells Vol.38 No.2

Lipoteichoic acid (LTA) is a major component of the cell wall of Gram-positive bacteria. Its effects on living organisms are different from those of lipopolysaccharide (LPS) found in Gram-negative bacteria. LTA contributes to immune regulatory effects including anti-aging. In this study, we showed that LTA isolated from Lactobacillus plantarum (pLTA) inhibited melanogenesis in B16F10 mouse melanoma cells. pLTA reduced the cellular activity of tyrosinase and the expression of tyrosinase family members in a dose-dependent manner. The expression of microphthalmia- associated transcription factor (MITF), a key factor in the synthesis of melanin, was also decreased by pLTA. Further, we showed that pLTA activated melanogenesis signaling, such as extracellular signal-regulated kinase (ERK) and phosphatidylinositol 3-kinse (PI3K)/AKT. In addition, the expression of heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) and HuR, which are important RNA-binding proteins (RBPs), was reduced. pLTA likely degrades MITF via regulation of melanogenic signaling and RNA stability of melanogenic proteins, resulting in the reduction of melanin. Thus, our data suggest that pLTA has therapeutic potential for treating hyperpigmentation disorders and can also be used as a cosmetic whitening agent.

Variants of Canine Urinary Bladder Tumors: Papillary Carcinoma and Pagetoid Carcinoma

Hae Kyoung Lim,Hye Rim Lee,Bong Hwan Jang,Sang Joon Park,Sun Hee Do 대한수의학회 2009 대한수의학회 학술대회발표집 Vol.2009 No.-

자궁내 악성 혼합성 중배엽종양 1예

박영한,유혜리,민봉식,장봉림 대한부인종양 콜포스코피학회 2002 Journal of Gynecologic Oncology Vol.13 No.2

난소종양에서 Cyclooxygenase - 2 의 발현

손우석(Woo Seok Sohn),민봉식(Bong Sik Min),김창모(Chang Mo Kim),김성주(Sung Joo Kim),강정배(Jung Bae Kang),박혜림(Hye Rim Park),장봉림(Pong Rheem Jang) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.7

Objective: A large body of evidence suggests that cyclooxygenase-2 (COX-2) is important in tumorigenesis of gastrointestinal and other cancers. This was the study to determine whether COX-2 was also expressed in benign and malignant ovarian tumors. Methods: We studied the expression of COX-2 in various ovarian tumors [ Benign epithelial tumors (n=10), borderline epithelial tumors (n=12), malignant epithelial tumor (n=12), nonepithelial tumors(n=10) ] by immunohistochemistry. Results of immunoreactivity was classified semiquantitatively based on the proportion and intensity of tumor cell immunostaining. Results: In the epithelial ovarian tumors, the intensity of immunostaining was stronger in the malignant tumors than the benign and borderline tumors (p<0.001). Especially all serous and mucinous malignant tumors (n=9) showed weak and strong immunoreactivity, with 66.7% strong reactivity. None of the nonepithelial ovarian tumors expressed COX-2 immunoreactivity. Conclusion: These preliminary data indicate that COX-2 may have a role in carcinogenesis of epithelial ovarian tums, especially in the serous and mucinous types. COX-2 maybe a target for future research in the tumorigenesis of the epithelial ovarian malignancies.

Phenotypic characteristics of<i>Streptococcus iniae</i>and<i>Streptococcus parauberis</i>isolated from olive flounder (<i>Paralichthys olivaceus</i>)

Nho, Seong-Won,Shin, Gee-Wook,Park, Seong-Bin,Jang, Ho-Bin,Cha, In-Seok,Ha, Mi-Ae,Kim, Young-Rim,Park, Yon-Kyoung,Dalvi, Rishikesh S.,Kang, Bong-Jo,Joh, Seong-Joon,Jung, Tae-Sung Oxford University Press 2009 FEMS microbiology letters Vol.293 No.1

<P>The etiological agents of streptococcosis were isolated from diseased olive flounder collected on the Jeju island of Korea. A total of 151 bacterial isolates were collected between 2003 and 2006. The isolates were examined using various phenotypic and proteomic analyses, including sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), immunoblotting, and glycoprotein assays. In addition, isolates were grown on blood agar to assess hemolytic activity, and biochemical assays were performed using the API20 Strep kit. Our results revealed that all isolates were nonmotile, Gram-positive cocci that displayed negative catalase and oxidase activities. Multiplex PCR assays revealed that 43% and 57% of the isolates were Streptococcus iniae and Streptococcus parauberis, respectively. These results were consistent with those of the SDS-PAGE and immunoblot analyses using whole-cell lysates of bacterial isolates. Significant differences were observed with respect to the Voges-Proskauer, pyrrodonyl arylamidase, alkaline phosphatase, and hemolytic activities of the S. iniae and S. parauberis isolates. Isolates of S. iniae displayed uniform profiles in the immunoblot and glycoprotein assays; however, immunoblot assays of S. parauberis isolates (using a chicken IgY antibody raised against a homologous isolate) revealed three distinct antigenic profiles. Our findings suggest that S. parauberis and S. iniae are endemic pathogens responsible for the development of streptococcosis in olive flounder.</P>

A malignant ovarian steroid cell tumor in a postmenopausal woman, managed with laparoscopic surgical staging: A case report

( Tae Yeem Lee ),( Ye Hyon Park ),( Hye Yon Cho ),( Jung Bae Kang ),( Bong Rim Jang ),( Min Sun Kyung ) 대한산부인과학회 2015 대한산부인과학회 학술대회 Vol.101 No.-

당뇨병환자의 자기조절교육 프로그램 효과와 지속에 관한 연구

홍명희 ( Myeong Hee Hong ),유주화 ( Joo Wha Yoo ),구미옥 ( Mee Ock Gu ),김순애 ( Soon Ai Kim ),이정림 ( Jeong Rim Lee ),구민정 ( Min Jeong Gu ),강양교 ( Yang Gyo Kang ),장숙희 ( Sook Hee Jang ),박봉숙 ( Bong Suk Park ),심강희 ( Ka 대한당뇨병학회 2009 임상당뇨병 Vol.10 No.3

연구배경: 당뇨병 치료의 성공여부는 환자 자신의 자기간호행위에 달려있으므로 환자교육이 매우 중요하다. 그러나 일회적인 교육은 단기적으로 관련 지식과 행위를 변화시키는데 효과적이나 장기적인 행동변화나 일상활동의 조절에는 제한점을 갖는다. 따라서 행위 조절을 유도하는 다른 중재 방법을 포함시킨 장기적이고 포괄적인 교육 프로그램이 보다 지속적인 행위 변화 효과를 기대하게 하므로 본 연구는 일반적인 당뇨병교육을 이수한 사람들 가운데 인슐린 주사요법으로 치료받고 있는 당뇨병환자를 대상으로 4주간의 자기조절교육 프로그램에 참여하게 하여 당뇨병 관리에 대한 자기효능을 높이고, 자기간호행위를 증진시킴으로써 혈당조절을 개선하고, 그 효과가 얼마간 지속되는지 여부를 확인하기 위하여 시도되었다. 방법: 본 연구는 제2형 당뇨병환자들로 6개월 이상 인슐린 치료를 받고 있고, 당화혈색소 7.5% 이상인 자로 실험군 46명, 대조군 37명을 대상으로 하였다. 실험군은 자기조절 교육을 받은 군이고, 대조군은 교육을 받지 않은 군이며, 독립변수는 자기조절교육 유무이며, 자료 수집은 교육을 시행하기 전, 4주간의 자기조절교육을 실시한 직후, 교육 후 2개월, 교육 후 6개월로 정하여 자기효능, 자기간호행위, 자기조절에 관한 설문지를 이용하여 총 4회에 걸쳐 수집하였고 혈당조절 측정은 교육 전, 교육 후 2개월, 6개월에 실시하였다. 결과: 1) 자기간호행위정도는 실험군과 대조군 간에 유의한 차이를 보였다(F=5.286, P=0.025). 자기간호행위는 시기에 따른 차이(F=5.336, P=0.005)가 두 군 간에 유의하였고, 시간 경과와 집단 간의 상호작용(F=5.514, P=0.004) 또한 두 군 간의 유의한 차이가 있는 것으로 나타났다. 2) 자기효능은 실험군과 대조군 간에 유의한 차이를 보이는 것으로 나타났다(F=29.409, P=0.000). 그러나 시기에 따른 차이(F=0.945, P=0.392) 및 시간 경과와 집단 간의 상호작용(F=1.442, P=0.241)은 두 군 간에 유의하지 않은 것으로 나타났다. 3) 혈당조절은 실험군과 대조군 간에 유의한 차이를 보이지 않았으나(F=0.627, P=0.432), 시기에 따른 차이(F=4.641, P=0.013)가 유의하게 나타났으며, 시간 경과와 집단 간의 상호작용(F=0.843, P=0.430)은 유의하지 않은 것으로 나타났다. 결론: 4주간의 자기조절교육 프로그램은 자기효능이나 자기간호행위는 증가시켰지만, 혈당조절에서는 유의한 차이가 없었다. 본 연구가 6개월 이상 장기적인 연구인 까닭에 대조군의 탈락자가 많이 발생한 점, 환자나 의료진 모두 인슐린 용량 증감에 대한 적극적인 개입이 어려웠다는 점, 또한 10년 이상 당뇨병을 가지고 살아가는 환자들의 생활습관의 변화를 유도하기는 쉽지 않다는 점을 고려할 때 당뇨병관리에 필요한 자기효능 및 자기간호행위를 강화시키기 위해서는 보다 효과적인 교육 프로그램의 개발과 반복적 연구가 필요하다. Background: This research was conducted to confirm whether 4-weeks self-regulation education program makes the diabetic patients, who are treated with injection of insulin, to improve their glucose adjustment and how long this effect will be persisted by self-care and improvement of self-efficacy. Methods: This research is object for 46 persons of test group and 37 persons of control group in type2 diabetics who are under the medical care more than 6 months and above HbA1c 7.5%. Test group is defined as self-regulation educated group and control group is not. Independent variables are defined whether self control education is trained or not. We compared self care score and self efficacy score with pre-education, post-education, at the point of 2 month later and 6 month later. Results: 1) The extent of self-care shows considerable difference between test group and control group (F=5.286, P=0.025). Self care indicates that it is connected to difference of period (F=5.336, P=0.005), lapse and interaction among the groups. 2) Self-efficacy appears to have shown the considerable difference between test group and control group (F=29.409, P=0.000). However, self efficacy does not seems to be connected with the gap of period (F=0.945, P=0.392), lapse, and interaction among the groups (F=1.442 P=0.241). 3) Blood glucose adjustment dose not show the considerable differences between test group and control group (F=0.627, P=0.432), However, the gap of period (F=0.627, P=0.432) has an effect to connect with blood glucose adjustment. Meanwhile, that is not seemed to connect with lapse and interaction among the groups (F=0.843, P=0.430).