Success and Failure of Surgical Endodontic Treatment in Molar Teeth

Geum, Yun-Seon,Lee, Jang-Ryeol,Kim, Hyeon-Cheol,Lee, Sang-Cheol,Kim, Yeong-Uk Korean Academy of Dental Science 2010 Journal of korean dental science Vol.3 No.2

Despite the latest advancement made in its techniques and devices/apparatuses and the resulting rising expectation in the field of dental surgery, apicoectomy performed in the molar teeth remains a technical challenge and lacks evidence substantiated by long-term follow-up studies. This study sought to investigate the treatment outcomes and post-operative success rate in the root-end resected molar teeth accompanied by a high level of surgical risks due to their close proximity to the mandibular canal and maxillary sinus. A total of 68 patients who received treatment at Livingwell Dental Hospital between 2004 and 2010 and underwent apical surgery in the maxillary or mandibular molar area were enrolled in this study. A total of 160 roots collected from 75 molar teeth were subjected to surgical endodontic treatment and subsequently evaluated clinically as well as radiographically. Based on the results of the study, the clinical success rate was found to be 78.8% in cases involving radiological healing. Likewise, 90.7% of the roots recorded a robust clinical survival rate, but with incomplete healing as shown by radiography. The results indicate that the apical procedure involving molar teeth is a prognosis-friendly method that promises positive outcomes and higher success rate based on long-term follow-up observations.

Success and Failure of Surgical Endodontic Treatment in Molar Teeth

Yun-Seon Geum,Jang-Ryeol Lee,Hyeon-Cheol Kim,Sang-Cheol Lee,Yeong-Uk Kim 대한치의학회 2010 Journal of korean dental science Vol.3 No.2

19세기 초 재미 한인의 국어교육 : 《신한민보》를 중심으로

윤금선 ( Yun Geum Seon ) 한국어교육학회 2004 국어교육 Vol.- No.113

GO-23 : Chemosensitivity testing based on gene expression profiling in patients with ovarian cancer

( Geum Seon Sohn ),( Hyeong Ju Kim ),( Ji Yun Lee ),( Jinkyoung Kong ),( Ji Hee Choi ),( Hanbyoul Cho ),( Eun Ji Nam ),( Sang Wun Kim ),( Sunghoon Kim ),( Jae Hoon Kim ),( Young Tae Kim ),( Doo Byung 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-

목적: To evaluate the association between clinical response of treatment agents and results of chemosensitivity testing in ovarian cancer. 방법: Tissue was obtained from 21 ovarian cancer patients and gene expression was evaluated by quantitative real-time polymerase chain reaction (PCR). Selected gene panel with expression of specific genes in the pathways that are related to drug responses in ovarian cancer were analyzed( AKT, Aurora A, BCRP, CD31, ERCC1, GSTpi, HER2, MDR1, Mitosin, PI3 Kinase, RRM1, Survivin, TOP1, TOP2A, TS, VEGF, VEGFR2, XIAP, P73). Gene expression were matched with therapeutic agent including Platinum, Taxanes, Bevacizumab, Gemcitabine, Topoisomerase I Inhibitors, Topoisomerase II Inhibitors, Cyclophosphamide, Herceptin, and 5-fluorouracil for chemosensitivity. 결과: Chemosensitivity testing revealed sensitivity rate of 66%, 81%, 96%, 56% and 61% for Platinum, Taxanes, Topoisomerase I Inhibitors, Topoisomerase II Inhibitors, and Bevacizumab, respectively. Treatment response rate was 70% (Complete Response: 40%, Partial Response: 30%). Treatment response was not significantly increased in the platinum sensitive patients (p=0.613), and overall response rate did not significantly differ according to the chemosensitivity test. 결론: This study may provide useful information in optimizing individual chemotherapy in the treatment of ovarian cancer.

Stress related activities of Sun-ginseng in SD Rats and ICR Mice

( Geum Seon Lee ),( Blendyl Saguan Tan Lee ),( Mi Kang Kim ),( Kyung Uoo Dong ),( Joo Yun Kim ),( Gu Young Yu ),( Jeong Sup Han ),( Hong Sook Ko ),( Il Ho Park ),( Jae Hoon Cheong ) 한국응용약물학회 2004 Biomolecules & Therapeutics(구 응용약물학회지) Vol.12 No.4

KARYOTYPES OF SIXTEEN SPECIES OF GOBIID FISHES FROM KOREA

YUN, MYEONG-JA,LEE, GEUM-YEONG,JANG, SEON-IL,SO, JUNE-NO 全北大學校 基礎科學硏究所 1987 基礎科學 Vol.10 No.1

A karyological analysis was carried out on different Korean species of the family Gobiidae (10 genera, 3 subfamies). The preparations were made according to the flame drying method, and the karyotypes were analyzed by conventional Giemsa staining. Diploid chromosome number ranged between 40 and 50 (Acanthogobius hasta, 44;A. sp., 42;A. lactipes, 40;A. flavimanus, 44;Acentrogobius pflaumi, 50; Rhinogobius brunneus, 44; Chasmichthys dolichognathus, 44; C. gulosus, 44; Chaenogobius abei, 46; Favonigobius gymnauchen, 48; Odontobutis platycephala, 44; Tridentiger obscurus, 44; T. sp., 44), and arm number was in the range of 40-96. Some detected chromosomal characteristics permitted establishing some karyotypic relationships among the different species investigated.

한국산 Gobiid fish 16 종의 핵형

이금영,소준노,장선일,윤명자 한국유전학회 1987 Genes & Genomics Vol.9 No.2

A karyological analysis was carried out on different Korean species of the family Gobiidae (10 genera, 3 subfamies). The preparations were made according to the flame drying method, and the karyotypes were analyzed by conventional Giemsa staining. Diploid chromosome number ranged between 40 and 50 (Acantho-gobius hasta, 44; A. sp., 42; A, lactipes, 40; A. flavimanus, 44; Acentro-gobius pflaumi, 50; Rhinogobius brunneus, 44; Chasmichthys dolichognathus, 44; C. gulosus, 44; Chaenogobius annularis, 44; C. castaneus, 42; C. mororanus, 42; Mugilogobius abei, 46; Favonigobius gymnauchen, 48; Odontobutis platycephala, 44; Tridentiger obscures, 44; T, sp., 44), and arm number was in the range of 40-96. Some detected chromosomal characteristics permitted establishing some karyotypic relationships among the different species investigated.

음주차수 증가에 따른 장소별 음주량과 알코올 의존

이금선(Geum-Seon Lee),윤미은(Mi-Eun Yun) 한국콘텐츠학회 2021 한국콘텐츠학회논문지 Vol.21 No.2

본 연구의 목적은 다회차 음주에 따른 장소별 음주량과 알코올의존을 분석하는 것이다. 국제 알코올 통제연구의 일환으로 2012년에 수집된 단면 데이터를 사용하였으며, 만19-64세 음주자 1,789명 중 855명을 대상으로 하였다. 다회차 음주자 비율은 남성(χ²=37.607, p<.001), 학생(χ²=52.466, p<.001), 미혼자(χ²=34.205, p<.001), 흡연경험이 있거나 스트레스가 있는 군(χ²=40,09, p<.001, χ²=21.66, p<.001)에서 유의적으로 높았다. 특히, 미혼자, 흡연자, 스트레스군의 알코올 섭취량이 기혼자, 비흡연자, 비스트레스군보다 유의적으로 더 높았다. 다회차에 걸쳐 알코올 섭취량이 가장 높은 장소는 주류 판매 업종인 술집으로 나타났다(F=67.8g, p<0.001). 음주자의 음주차수가 증가할수록 총 알코올 섭취량이 증가하였으며(F=209.993, p<0.001) 알코올의존도 검사인 RAPS4와 DSM-IV에서 양성 반응을 나타낸 음주자의 수(%)가 각각 (F=129.836, p<0.001; F=94.669, p<0.001) 증가하였다. 음주자 중 알코올의존 교차비는 남성이 여성보다 2.3(95% CI: 1.745-3.057)배, 무직자는 직장인보다 3차에서 3.2(95% CI: 1.053-9.838)배, 흡연자는 비흡연자보다 3차에서 3.9(95% CI: 1.230-12.292)배, 그리고 스트레스군도 비스트레스군보다 2.1(95% CI:1.561-2.768)배 높았다. 결론적으로 음주차수가 증가할수록 흡연여부나 스트레스와의 관련성과 알코올 의존도가 높아져 알코올에 더 취약할 수 있음을 시사한다. The purpose of this study was to analyze the alcohol volume consumed and alcohol dependancy according to multiple rounds of drinking. Sectional data collected in 2012 as part of an International Alcohol Control Study were used, and 855 of 1,789 drinker aged 19 to 64 were conducted. The proportion of multiple rounds drinking were significantly higher in males(χ²=37.607, p<.001), students(χ²=52.466, p<.001), single(χ²=34.205, p<.001), smoking experience and stressed(χ²=40,09, p<.001; χ² =21.66, p<.001) among drinkers. In particular, the alcohol volume consumed of unmarried people, smokers, and stress groups were significantly higher than married people, non-smokers and no-stress group. The highest alcohol intake in the first, 2nd and third rounds was found in bars in the liquor trade (F=67.8g, p<0.001). The total alcohol intake increased as the number of rounds increased (F=209.993, p=0.001) and the number of drinkers who tested positive for alcohol dependency increased, using the tests RAPS4 and DSM-IV(F=129.836, p<0.001; F=94.669, p<0.001). The OR of alcohol dependancy in males was 2.3(95% CI: 1.745-3.057), unemployed was 3.2(95% CI: 1.053-9.838), smokers was 3.9(95% CI: 1.230-12.292), and stress group was 2.1(95% CI: 1.561-2.768) compared to females, employed, non-smokers, and no-stress group respectively. In conclusion, it suggests that those consuming multiple rounds drinking can become more vulnerable to alcohol harms due to its relation to smoking, stress and increased dependence on alcohol.

수경재배 인삼의 부위별 진세노사이드 분석

김금숙(Geum-Soog Kim),현동윤(Dong Yun Hyun),김영옥(Young Ock Kim),이승은(Seung Eun Lee),권혁(Hyuck Kwon),차선우(Seon Woo Cha),박충범(Chung Berm Park),김용범(Young Bum Kim) 한국원예학회 2010 원예과학기술지 Vol.28 No.2

인삼은 일반적으로 약용으로 사용하기 위해 4-6년근을 재배하여 백삼 또는 홍삼으로 사용한다. 본 연구에서는 인삼을 기능성 채소로서의 가능성을 평가하기 위해 120일 동안 여러 종류의 혼합배지에서 단기 수경재배한 후 인삼의 뿌리, 잎, 줄기 등 부위별 ginsenoside 함량과 조성을 분석하였다. 뿌리와 잎에서는 모든 혼합배지 종류에서 total ginsenoside 함량이 1월 정식재배 조건보다는 3월 정식재배 조건에서 더 높았다. 특히 뿌리와 잎은 각각 T5(황토:펄라이트:팽화왕겨=4:3:3), T6(모래:원예상토=4:6) 혼합배지에서 그 함량이 1.47, 16.06%로서 가장 높았다. 반면에 줄기는 1월 정식재배 조건에서 그 함량이 더 높았으며, 특히 T5 혼합배지에서 그 함량이 1.39%로서 가장 높았다. 수경재배 인삼의 잎에는 다년근 수삼에서는 거의 검출이 되지 않는 Rh1 성분이 0.15-0.25%(T5, T6 배지) 함유되어 있고, 인삼 뿌리와는 다른 조성비를 나타내어 Rd 성분이 Rg1 다음으로 다량 함유되어 있었다. 인삼 뿌리, 잎, 줄기의 PD/PT 비율은 각각 0.5-0.6, 0.5-0.7, 0.1-0.2(1월 및 3월 정식재배 T5, T6 배지) 정도로서 일반 다년근 재배인삼의 뿌리보다 낮았다. 결론적으로, 인삼의 ginsenoside 성분이 우수한 수경재배 조건은 3월 정식재배의 T5, T6 혼합배지 조건이었으며, 이 수경재배 조건에서 인삼 잎은 뿌리와 줄기에서보다 total ginsenoside 함량이 높았다. 이것은 수경재배 인삼이 뿌리 단독보다는 뿌리와 잎, 줄기를 모두 활용하는 기능성 채소로서 우수한 소재임을 시사하였다. It has been known that 4-6 years old roots of Panax ginseng are used traditionally for medicinal purpose as white ginseng or steamed red ginseng. In this research, the contents and composition of ginsenoside in different parts such as root, leaf, and stem of Panax gingeng were investigated after short term hydroponics in several kinds of mixed culture media for 120 days to evaluate Panax ginseng as new functional vegetables. Total ginsenoside contents of root and leaf were higher on the ginsengs cultured after planting on March 25, 2008 (PMar) than planting on January 20, 2008 (PJan), regardless of the kinds of mixed culture media. Especially, total ginsenoside contents in root and leaf were the highest as 1.47 (T5 culture medium; Loess:Perlite:Expanded rice hull mixed 4:3:3) and 16.06% (T6 culture medium; Sand:Horticultural substrate mixed 4:6), respectively. On the other hand, the content of total ginsenoside in stem was higher in PJan, and the content was the highest as 1.39% in T5 culture medium. Rh1 that is hardly detected in 4-6 years old ginseng root was contained in leaf of hydroponics ginseng as 0.15-0.25% (T5, T6). Leaf of hydroponics ginseng showed that Rd was second ingredient next to Rg1, differently from ginseng root. The ratio of protopanaxdiol (PD) and protopanaxatriol saponins (PT) in root, leaf, and stem of Panax ginseng were lower than root of 4-6 years old ginseng as 0.5-0.6, 0.5-0.7, and 0.1-0.2 (PJan, PMar; T5, T6), respectively. Conclusively, T5 and T6 culture media of PMar condition were the most excellent hydroponics condition due to high ginsenoside content, and the content of total ginsenoside in leaf was significantly higher than in root and stem, which suggested that the whole ginseng plant including root, leaf, and stem might be an excellent source as new functional vegetables.

검정콩 섭취여부에 따른 일부 대학생의 영양소 섭취상태

이금선 ( Geum-seon Lee ),윤미은 ( Mi-eun Yun ) 대한영양사협회 2021 대한영양사협회 학술지 Vol.27 No.1

This study analyzed the intake of calories and nutrients based on the consumption of black beans. The survey was conducted on 124 college students (male: 42, female: 82), of whom 63.7% (79 students) were consumers of black beans. The calorie intake of the black bean intake group (1599.81±555.48 kcal) was significantly higher than that of the non-black bean intake group (1259.99±507.58 kcal) (P<0.01). The black bean intake group also showed a significantly higher intake of crude protein (P<0.05), plant protein (P<0.01), animal protein (P<0.05), crude fiber (P<0.001), plant calcium (P<0.001), plant iron (P<0.001), zinc (P<0.01), vitamin B₂ (P<0.01), vitamin C (P<0.01), vitamin E (P<0.01) and folic acid (P<0.001) compared to the non-black bean intake group. There was a positive correlation between the frequency of black bean intake and crude fiber (P<0.05), plant calcium (P<0.05), plant iron (P<0.05), and folic acid (P<0.05). Overall, the black bean intake group was more likely to eat black sesame 13.82 times (95% CI=5.37, 35.55), white beans 10.79 times (95% CI=3.53, 33.02), mung beans 7.22 times (95% CI=2.58, 20.23), and brown rice 4.72 times (95% CI=1.88, 11.84), than the non-black bean intake group. In conclusion, we believe that black beans constitute a vital food ingredient that is necessary to provide Korean college students with a well-balanced diet.